Clinical trials: Vitamin D Insufficiency
Chronic Kidney Diseases, Osteodystrophy
Effect of Allopurinol on Markers of Mineral and Bone Metabolism
Hyperuricemia is a common condition in patients with chronic kidney disease (CKD) in the glomerular filtration rate. Recently, it has been suggested that uric acid is related to a mineral and bone disease of CKD (CKD-MBD) since…
- Conditions
- Chronic Kidney Diseases, Osteodystrophy, Uric Acid Concentration, Serum, Quantitative Trait Locus 7
- Trial name
- NCT05601271
- Testing
- Allopurinol
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- University of Sao Paulo General Hospital
Chronic Kidney Diseases, Hypertension
Integrated Diagnosis and Treatment of CKD on Outcomes
Objective: To establish a study cohort and follow up of patients with CKD in our hospital, and evaluate the status of integrated CKD diagnosis and treatment according to guidelines in the real world, as well as the clinical…
- Conditions
- Chronic Kidney Diseases, Hypertension, Hyperglycemia, Hyperlipidemias
- Trial name
- NCT05242055
- Testing
- Integrated diagnosis and treatment for CKD
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Capital Medical University
Vitamin D Deficiency
The Effect of Vitamin D on Bone Accretion and Turn-Over in Young Girls
Objectives To evaluate the effect of increased vitamin D intake on vitamin D status, bone mass and bone turnover in young girls aged 12-13.
- Trial name
- NCT00267540
- Testing
- cholecalciferol (D3) (vitamin)
- Where
- Denmark
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Chronic Kidney Disease
Vitamin D Supplementation and Cardiac Hypertrophy in Chronic Kidney Disease (CKD)
Patients with Chronic Kidney Disease (CKD) are upto 3.5 times more likely to die from diseases of heart and blood vessels (Cardiovascular Disease-CVD). Vitamin D insufficiency is very common in CKD and associated with CVD.
- Trial name
- 5C (NCT01323712)
- Testing
- Vitamin D Cholecalciferol
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- St George's, University of London
Cardiovascular Disease, Chronic Kidney Disease
Vascular Risk After Kidney Transplantation
Hypothesis: Nontraditional risk factors, such as inflammation, vitamin D deficiency, elevated PTH, insulin resistance, homocysteine, or uric acid, contribute to cardiovascular disease progression after kidney transplant.
- Conditions
- Cardiovascular Disease, Chronic Kidney Disease, Diabetes, Vitamin D Deficiency
- Trial name
- NCT00374595
- Where
- United States
- Volunteers
- 338 people
- Sponsor
- University of Nebraska
Chronic Kidney Disease, Endothelial Dysfunction
Study of Protective Effects of Paricalcitol on Inner Layer of Vessels and Its Protective Effect on Inflammation
The study is about possible protective effects of paricalcitol (Zemplar) upon inflammation, blood pressure and kidney function. Kidney Inflammation occurs when white blood cells become abnormally stimulated and accumulate in the…
- Conditions
- Chronic Kidney Disease, Endothelial Dysfunction, Inflammation, Hypertension
- Trial name
- NCT00428246
- Testing
- paricalcitol
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Indiana University
Hyperphosphatemia
The Effect of Oral Niacinamide on Serum Phosphorus Levels in Hemodialysis Patients
Elevated phosphorus levels are a common problem in dialysis patients. However, it is associated with an increase in death and hospitalizations.
- Trial name
- NCT00316472
- Testing
- Niacinamide
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Washington University School of Medicine
Healthy
Defining Vitamin D Insufficiency in School Age Children: A Randomized Placebo Controlled Trial of Vitamin D3
The study objective is to characterize the threshold levels of serum 25-hydroxyvitamin D for the definition of vitamin D insufficiency in 8-14 year old African American and Caucasian children.
- Trial name
- Vitamin D RCT (NCT00732758)
- Testing
- Vitamin D3 1000 IU
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Cardiorenal Syndrome, Chronic Allograft Nephropathy
Paricalcitol Versus Calcitriol for the Management of Renocardiac Syndrome in Renal Transplant Patients
We hypothesize that paricalcitol and calcitriol in dose-dependent manner are effective for the management of chronic allograft dysfunction (CAD), protection and repair of kidney and heart, management of chronic renocardiac…
- Trial name
- NCT01265615
- Testing
- Paricalcitol, Calcitriol, Cholecalciferol
- Where
- 2 sites in Netherlands, Russia
- Volunteers
- 109 people
- Sponsor
- Ural State Medical University
Vitamin D Deficiency, Polytrauma
Vitamin D and Bone Homeostasis in Ortho Polytrauma Patients
Although vitamin D is known to play a major role in multiple organ functions in healthy adults, including bone homeostasis, its role in the unique population of orthopaedic polytrauma patients has not been well described.
- Conditions
- Vitamin D Deficiency, Polytrauma, Orthopedic Disorder
- Trial name
- NCT03066817
- Testing
- Ergocalciferol 8000 IU/ML Oral Liquid [DRISDOL], Propylene Glycol
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- New York City Health and Hospitals Corporation
Healthy Adult Participants, Vitamin D Insufficiency
Supplementation of Cholecalciferol and Related Active Metabolites Through Bioenhancing Layer's Eggs
The purpose of this research is to evaluate if 1) consumption of vitamin D3- or 25(OH)D3-biofortified eggs will increase vitamin D and 25(OH)D status in young adults who consume these bioenhanced eggs, 2) to determine if the gut…
- Trial name
- SCRAMBLE (NCT07859280)
- Testing
- Vitamin D3 bioenhanced eggs, 25(OH)D3 bioenhanced eggs
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cornell University
Chronic Kidney Disease
The Effect of Paricalcitol on Creatinine Filtration, Secretion and Glomerular Filtration Rate
The purpose of this study is to study the effects of Paricalcitol (Zemplar) on kidney functioning. The investigators hypothesize that the increase in serum creatinine observed in recent paricalcitol trials is a function of…
- Trial name
- Paricalcitol (NCT01163162)
- Testing
- Paricalcitol
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Indiana University
Vitamin D Deficiency, Dental Implant Failure Nos
Vitamin D and Serum Calcium Level Insufficiency and Early Dental Implant Failure
In this study there is a trial to investigate whether there is a correlation between early implant failure and low serum levels of vitamin D.
- Trial name
- NCT04906161
- Testing
- Vitamin D and calcium levels
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Hypertensive Disorders of Pregnancy
Vitamin D and Hypertensive Disorders of Pregnancy
The purpose of this study is to further investigate the association between vitamin D deficiency/insufficiency and hypertensive disorders of pregnancy by studying the impact of screening for vitamin D deficiency and…
- Trial name
- NCT07017920
- Testing
- Vitamin D Levels measurement
- Volunteers
- 594 people
- Sponsor
- TriHealth Inc.
Secondary Hyperparathyroidism, Chronic Kidney Disease
Paricalcitol Versus Calcitriol for Efficacy and Safety in Stage 3/4 Chronic Kidney Disease (CKD) With Secondary Hyperparathyroidism (SHPT)
Secondary Hyperparathyroidism (SHPT) occurs in many patients with kidney disease and leads to bone disease. Active forms of vitamin D, calcitriol and paricalcitol, treat SHPT, but may have different effects on blood calcium.
- Trial name
- PACE (NCT00823303)
- Testing
- Paricalcitol, Calcitriol
- Where
- 4 sites in United States
- Volunteers
- 110 people
- Sponsor
- Washington University School of Medicine
Vitamin D Deficiency
Effects of Vitamin D Insufficiency in Man
We would like to determine if vitamin D insufficiency exists in different ethnic groups, if it has an effect on bone mass and muscle function, if it has an impact on the function of the cells of the immune system, and if the…
- Trial name
- NCT01848236
- Testing
- Vitamin D2, Vitamin D3
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Chronic Kidney Disease
Vitamin D Repletion in Chronic Kidney Disease
The reason for doing this research is that people with kidney disease often suffer from heart disease. Why this happens is not fully known.
- Trial name
- NCT00772772
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
COVID
Cholecalciferol to Improve the Outcomes of COVID-19 Patients
The recent inception of the coronavirus SARS-CoV-2, responsible for the coronavirus disease (COVID-19), has caused thousands of deaths globally.
- Trial name
- CARED (NCT04411446)
- Testing
- Vitamin D
- Where
- Argentina
- Volunteers
- 218 people
- Sponsor
- Vitamin D Study Group
Chronic Kidney Diseases
Pilot Study- Treat to Target Vitamin D in End Stage Renal Disease
Feasibility of dose adjustment to reach a 6 month 25-hydroxy vitamin D level of 35-50 ng/ml in end stage renal disease patients
- Trial name
- NCT04167111
- Testing
- Cholecalciferol
- Sponsor
- University of Nebraska
Kidney Failure, Chronic, Anemia
Cholecalciferol Supplementation for Anemia and Mineral and Bone Disorder in Hemodialysis Patients
The purpose of this study is to determine whether cholecalciferol supplementation decrease the blood concentrations of hepcidin-25 in hemodialysis patients.
- Conditions
- Kidney Failure, Chronic, Anemia, Vitamin D Deficiency, Bone Diseases, Metabolic
- Trial name
- CHAMBER (NCT02214563)
- Testing
- Cholecalciferol, Olive oil
- Where
- 7 sites in Japan
- Volunteers
- 90 people
- Sponsor
- Takayuki Hamano