Clinical trials: Young
Neonatal Diabetes, Monogenic Diabetes
China Monogenic Diabetes Registry
This observational study aims to establish a digital registry, screening platform for patients with monogenic diabetes using internet-based and mobile application technologies.
- Conditions
- Neonatal Diabetes, Monogenic Diabetes, Maturity Onset Diabetes of the Young
- Trial name
- CMDR (NCT07492004)
- Testing
- No Interventions
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Tianjin Medical University General Hospital
Complex Care, Medical Complexity
Complexity in Health, Education, and Social Support for Children and Young People With Life-limiting Conditions.
Children and young people (CYP) with life-limiting conditions represent a growing population with complex care needs that span health, education, and social care systems.
- Conditions
- Complex Care, Medical Complexity, Pediatrics, Life-limiting Illness
- Trial name
- CHESS (NCT07102433)
- Testing
- Children and young people with life-limiting conditions, their parents/carers, and professionals across healthcare, education, and social care sectors.
- Where
- 5 sites in United Kingdom
- Volunteers
- 170 people
- Sponsor
- King's College London
Healthy, Family Research
Pediatric Parenting Support in Flint
Public health disasters have disproportionate impacts on low income communities, through pathways that add to those of poverty and associated stressors, and act over extended periods.
- Trial name
- NCT03945552
- Testing
- Video Interaction Project
- Where
- 2 sites in United States
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Leukemia
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00558519
- Testing
- cyclophosphamide, cytarabine, daunorubicin hydrochloride
- Volunteers
- 318 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Solid Tumors
Topotecan, Ifosfamide and Carboplatin in Children and Young Adults With Solid Tumors
Primary Objectives: To determine the maximum tolerated dose (MTD) of Topotecan when added to a fixed dose regimen of Ifosfamide and Carboplatin in children and young adults with solid tumors.
- Trial name
- NCT00502892
- Testing
- Topotecan, Ifosfamide, Carboplatin
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- M.D. Anderson Cancer Center
Cognitive Function
The Cognitive Functioning of Young Athletes Including Bioelectrical Brain Function
The project focuses on two central issues: 1. The impact of intensity of sport on the cognitive functioning and brain waves of children in late childhood (10-12 years old); 2.
- Trial name
- NCT04753047
- Testing
- No intervention
- Where
- 2 sites in Poland
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- University of Gdansk
Anaerobic Performance, Athletic Performance
Warm-Up Music Tempo and Time-of-Day Effects on Anaerobic Performance in Young Female Volleyball Players
This study examined whether listening to music of different tempo during warm-up is associated with differences in acute jump performance, perceived exertion and handgrip strength in young female volleyball players, and whether…
- Conditions
- Anaerobic Performance, Athletic Performance, Warm-Up Music Tempo, Time-of-Day Effects
- Trial name
- NCT07891858
- Testing
- No Music Warm-Up, Low-Tempo Music Warm-Up, Moderate-Tempo Music Warm-Up
- Where
- Turkey (Türkiye)
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Inonu University
Aortic Aneurysm and Dissection
Young Patient With Aortic Dissection or Aneurysm: A Prospective Observational Cohort Study
Aortic dissection or aneurysm is unusual in young patients, and frequently associated with unusual presentations. However studies about this area is scarce. Besides, the treatment option is not clare.
- Trial name
- NCT04431336
- Testing
- movement
- Volunteers
- 100 people
- Sponsor
- Chinese Medical Association
Gonorrhea Female, Chlamydia Females
The Integrated Female Sexually Transmitted Infection Testing for HIV Epidemic Control Through PrEP (IN-STEP) Study
Globally, new HIV infections are concentrated in eastern and southern Africa where the infections are largely acquired by women outside of known key populations.
- Conditions
- Gonorrhea Female, Chlamydia Females, Syphilis Female, Trichomonas Vaginalis
- Trial name
- IN-STEP (NCT06743204)
- Testing
- Self-Reported Risk Screening for PrEP and Diagnostic STI testing, Self-reported risk screening for PrEP and syndromic management for STIs
- Where
- Uganda
- Volunteers
- 5,560 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Depression, Anxiety
Effectiveness of Enhanced Mental Health Support for Young People
The aim of the research project is to measure the effectiveness of an early and rapid psychiatric nurse intervention at schools in improving the emotional well-being and functioning of adolescents.
- Conditions
- Depression, Anxiety, Emotional Stress
- Trial name
- Nopsatuki (NCT05356949)
- Testing
- Intervention
- Where
- Finland
- Volunteers
- 124 people
- Sponsor
- Turku University Hospital
Diabetes (Insulin-requiring, Type 1 or Type 2), Pediatric Diabetes
A Novel Miniature Equine-Assisted Diabetes Education Program for Youth: Evaluating the Diabetes Equine Empowerment Program (DEEP).
The Diabetes \& Equine Empowerment Program (DEEP) is a research study evaluating a novel diabetes education program that combines hands-on interactions with miniature horses and evidence-based diabetes self-management education…
- Conditions
- Diabetes (Insulin-requiring, Type 1 or Type 2), Pediatric Diabetes, Diabetes (DM)
- Trial name
- DEEP (NCT07822555)
- Testing
- Diabetes & Equine Empowerment Program (DEEP)
- Volunteers
- 50 people
- Sponsor
- Nemours Children's Clinic
Amblyopia
Prospective Evaluation of a Smartphone Application, GoCheckKids™, to Detect Amblyopia Risk Factors in Young Children
The objective is evaluation of GoCheck Kids, a smartphone application ('App'), for use as a photo screening device in a pediatric population to detect amblyopia risk factors (ARFs).
- Trial name
- NCT03447171
- Testing
- App Vision Screening
- Where
- United States
- Volunteers
- 207 people
- Sponsor
- Gobiquity Mobile Health
Behavior, Health, Behavior, Smoking
Evaluation of The Stanford Tobacco Prevention Toolkit
The Stanford Tobacco Prevention Toolkit is a free online curriculum developed for use by educators and health professionals in providing tobacco-specific prevention education to middle and high school students.
- Trial name
- NCT04467034
- Testing
- Stanford Tobacco Prevention Toolkit curriculum
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stanford University
Sports Physical Therapy
Effects of Post Isometric Relaxation and Post Facilitation Stretching on Young Fast Bowlers
The quadratus lumborum muscle exhibited the highest degree of asymmetry in fast bowlers with low back pain, the identification and correction of this asymmetry is always of interest.
- Trial name
- (PIR)(PFS) (NCT06479538)
- Testing
- Post isometric relaxation, Post facilitation stretching
- Where
- Pakistan
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Acute Lymphoblastic Leukemia
Whole Genome Sequencing (ChromoSeq®) for Acute Lymphoblastic Leukemia (ALL) Patients
This is a prospective data collection study evaluating the feasibility of using the ChromoSeq® assay for upfront classification in a real-time clinical setting of pediatric and young patients suspected of having ALL.
- Trial name
- NCT07313592
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Washington University School of Medicine
Adolescent - Emotional Problem, Parent Child Relationship
Randomized Controlled Trial of a Family-focused Intervention for Caregivers and Young Adolescents (Phase 3 of FLOURISH)
The aim of this study is to conduct a multi-country randomized waitlist controlled trial to evaluate the effectiveness, cost-effectiveness, and scalability of the optimized Parenting for Lifelong Health (PLH) for Parents and…
- Conditions
- Adolescent - Emotional Problem, Parent Child Relationship, Family Functioning, Well-Being, Psychological
- Trial name
- FLOURISH (NCT07240571)
- Testing
- Optimized Parenting for Lifelong Health (PLH) for Parents and Teens
- Where
- 2 sites in Moldova, North Macedonia
- Volunteers
- 1,280 people, healthy volunteers welcome
- Sponsor
- University of Klagenfurt
Acute Otitis Media
Efficacy of Short-Course Antimicrobial Treatment for Children With Acute Otitis Media and Impact on Resistance
The investigators will study whether, in young children with acute otitis media (AOM), shortening length of antibiotic treatment as a strategy for reducing antimicrobial resistance provides satisfactory clinical outcome.
- Trial name
- NCT01511107
- Testing
- Amoxicillin-Clavulanate, 10 days, Amoxicillin-Clavulanate, 5 days
- Where
- 2 sites in United States
- Volunteers
- 520 people
- Sponsor
- Alejandro Hoberman
Dental Plaque (Diagnosis), Deep Learning
Microbial Dental Plaque Analysis in Young Permanent Teeth Using Deep Learning
Background: Dental plaque contributes to a number of common oral conditions such as caries, gingivitis, and periodontitis. As a result, detection and management of plaque is of great importance for the oral health of individuals.
- Trial name
- NCT06603233
- Testing
- The Difference Between The AI Model and Dentists Group, Deep Learning Models
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Ankara Medipol University
Leukemia, Acute Lymphoblastic
Effect of Fish Oil on Hyperlipidemia and Toxicities in Children and Young Adults With Acute Lymphoblastic Leukemia
Acute lymphoblastic leukemia (ALL) is the most common malignant disease among children. Treatment results have improved over time due to intensive risk-adapted therapy and the 5-year survival rate is now above 90%.
- Trial name
- NCT04209244
- Testing
- Eskimo-3 Pure Fish Oil, Rapeseed Oil
- Where
- 4 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Constitutional Mismatch Repair Deficiency Syndrome, Hematopoietic and Lymphoid Cell Neoplasm
Testing the Combination of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) in Children, Adolescent, and Young Adult Patients With Relapsed/Refractory Cancers That Have an Increased Number of Genetic Changes, The 3CI Study
This phase Ib trial investigates the side effects of the combination of nivolumab and ipilimumab, and to see how well they work in treating patients with cancers that have come back (relapsed) or does not respond to treatment…
- Conditions
- Constitutional Mismatch Repair Deficiency Syndrome, Hematopoietic and Lymphoid Cell Neoplasm, Lynch Syndrome, Recurrent Lymphoma
- Trial name
- NCT04500548
- Testing
- Biospecimen Collection, Ipilimumab, Nivolumab
- Where
- 9 sites in United States, Canada
- Sponsor
- National Cancer Institute (NCI)
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