Clinical trials: a Randomized Controlled Trial
Surgery, Anxiety
Pediatric Preoperative Virtual Reality Program
Does the introduction of a preparatory virtual reality (VR) program that is used in the home environment, have an effect on the anxiety level of children immediately before surgery, prior to administration of preoperative…
- Trial name
- PPVRP (NCT03957525)
- Testing
- Pre-Operative Preparatory Virtual Reality Program
- Where
- Switzerland
- Volunteers
- 11 people
- Sponsor
- Thoralf Liebs
Laceration
Virtual Reality vs. Standard-of-Care for Comfort During Laceration Repair
Lacerations are a common reason for presentation to the Emergency Department and children needing laceration repair with sutures are experiencing pain and anxiety.
- Trial name
- NCT03681717
- Testing
- Virtual Reality
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- University of British Columbia
Pits and Fissure Sealants
A Comparative Evaluation of the Role of Self-Adhesive Flowable Composite in Enhancing Sealant Retention Versus Conventional Pits and Fissure Sealant With and Without Fissurotomy in Permanent Molars
This RCT study aims to establish evidence-based decision comparing between self-adhering flowable composite Vertise™ Flow (Kerr, Orange, CA, USA) and conventional resin-based pits \& fissure sealant Helioseal-F sealant (Ivoclar…
- Trial name
- NCT07399340
- Testing
- Self adhering flowable composite Vertise™ Flow (Kerr, Orange, CA, USA) with fissurotomy., Self adhering flowable composite Vertise™ Flow (Kerr, Orange, CA, USA) without fissurotomy., Conventional resin-based pits and fissure sealant Helioseal-F with fissurotomy.
- Where
- 2 sites in Egypt
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Cairo University
Type 1 Diabetes, Motivational Interviewing
The Impact of Motivational Interviews Conducted Through Tele-Nursing on Diabetes Management
The deterioration of glycemic control in adolescents with Type 1 diabetes (T1DM) is a genuine cause for concern. Possible reasons for worsening glycemic control in youth include lack of monitoring, inadequate self-care…
- Trial name
- NCT06208618
- Testing
- Education and Motivational Interviews
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Eskisehir Osmangazi University
Pain, Postoperative
Analgesic Efficacy of Bilateral US Guided TTPB vs ESPB in Pediatric Patients Undergoing Corrective Cardiac Surgeries
Corrective cardiac surgeries include a bundle of major surgeries that take place in pediatric patients and require imperative perioperative pain control; hence, the art of healing starts from trying to diminish or abolish pain.
- Trial name
- NCT05559684
- Testing
- Erector spinae plane block, Transversus thoracis plane block
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Stress, Emotional
Resilience Curriculum for Novice Physicians-in-training
To determine the feasibility of delivering a structured resilience curriculum to novice physicians-in-training, we propose a pilot study to evaluate recruitment rates, course attendance and compliance with follow-up surveys.
- Trial name
- NCT04977726
- Testing
- STRIVE curriculum
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Intubation
Head Position on Pediatric Nasotracheal Intubation
The aim of study is to evaluate whether the head position facilitates pediatric nasotracheal intubation when using a video-laryngoscope.
- Trial name
- NCT05164276
- Testing
- Head position
- Where
- South Korea
- Volunteers
- 108 people
- Sponsor
- Ajou University School of Medicine
Neurologic Deficits
NeuroVision vs Standard Neuromonitoring
The purpose of this study is to perform a prospective, randomized, controlled clinical trial to assess the utility of IONM in patients undergoing primary, single or multilevel lateral spinal procedures.
- Trial name
- NCT04639297
- Testing
- NeuroVision® IONM, Hospital Based IONM
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Type 1 Diabetes Mellitus
Examining the Influence of Guided Meditation on Diabetes-related Distress and Glycemic Control
The study aims to investigate the effects of Guided Meditation on diabetes-related distress and glycemic control in hospitalized Type 1 adolescent diabetic patients.
- Trial name
- NCT06151821
- Testing
- Guided meditation
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Shifa International Hospital
Depression, Social Anxiety
Effectiveness and Cost Effectiveness of OkeyMind for Social Anxiety Among Youth
This randomized controlled trial aims to evaluate the effectiveness and cost-effectiveness of a mobile-based psychoeducation program (OkeyMind) in mitigating symptoms associated with social anxiety among youth.
- Trial name
- NCT06490315
- Testing
- OkeyMind intervention, Wait-list control
- Where
- Hong Kong
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Hong Kong Shue Yan University
Critical Illness
Topical Application of Silver Nanoparticles and Oral Pathogens in Ill Patients
The purpose of this study is to determine whether oral topic silver nanoparticles are effective to reduce potential pathogen microbial loads in mechanical ventilation patients.
- Trial name
- NCT02761525
- Testing
- silver nanoparticles
- Volunteers
- 50 people
- Sponsor
- Universidad Autonoma de San Luis Potosí
Procedural Pain
Intranasal Versus Intravenous Fentanyl For Procedural Analgesia in Preterm Neonates
Pain in neonatal life has profound long-term developmental impacts, so pain control is crucial. The intranasal (IN) route is a minimally invasive method for rapidly delivering fentanyl to provide short-term analgesia and sedation…
- Trial name
- NCT07190625
- Testing
- fentanyl intravenous, Fentanyl intranasal using atomizer, fentanyl intranasal direct
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Healthy Subjects
Trial Evaluating a 13-valent Pneumococcal Conjugate Vaccine Given With Diphtheria, Tetanus, and Acellular Pertussis Vaccine (DTaP) in Healthy Japanese Infants
Subjects will be randomly assigned to 1 of 3 groups to receive the following vaccines: Group 1: 13-valent pneumococcal conjugate vaccine (13vPnC) and diphtheria, tetanus, and acellular pertussis vaccine (DTaP), Group 2: 7-valent…
- Trial name
- NCT01200368
- Testing
- 13-valent pneumococcal conjugate vaccine (13vPnC), diphtheria, tetanus, and acellular pertussis vaccine (DTaP), 7-valent pneumococcal conjugate vaccine (7vPnC)
- Where
- 32 sites in Japan
- Volunteers
- 551 people
- Sponsor
- Pfizer
Type 1 Diabetes Mellitus
A Phase III Study to Investigate if the Study Drug Diamyd Can Preserve Insulin Production and Improve Glycemic Control in Patients Newly Diagnosed With Type 1 Diabetes
The objective of DIAGNODE-3 is to evaluate the efficacy and safety of three intranodal injections of 4 μg of Diamyd also known as retogatein compared to placebo, along with oral Vitamin D supplementation, to preserve endogenous…
- Trial name
- DIAGNODE-3 (NCT05018585)
- Testing
- Recombinant human glutamic acid decarboxylase (rhGAD65) formulated in Alhydrogel®, Colecalciferol 2000 IU
- Where
- 60 sites in United States, Czechia and 7 more
- Volunteers
- 321 people
- Sponsor
- Diamyd Medical AB
Dental Caries
Retention and Caries Prevention of Giomer Sealant With or Without Diode Laser Pre-treatment: A Randomized Controlled Trial
This randomized controlled trial evaluates the effect of diode laser pre-treatment on the retention and caries prevention of giomer-based fissure sealants in young adults aged 17-22 years.
- Trial name
- NCT07612540
- Testing
- phosphoric acid pretreatment
- Where
- 3 sites in Egypt
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Cairo University
Scoliosis Idiopathic
Effect of Hippotherapy and Schroth Exercise on Pulmonary Function and Aerobic Capacity in Idiopathic Scoliosis
BACKGROUND: Idiopathic scoliosis has been identified as a common spinal malalignment that negatively impacts the respiratory system and physical conditioning in adolescents.
- Trial name
- NCT04833868
- Testing
- hippotherapy and schroth exercise, schroth exercise
- Where
- Saudi Arabia
- Volunteers
- 45 people
- Sponsor
- Batterjee Medical College
Family Witnessed Resuscitation, Empathy Education
VIDEO LEARNING FOR EMPATHY, ETHICS AND FAMILY WITNESSED RESUSCITATION
This clinical trial (randomized controlled experimental study) aims to learn about the effects of presenting the family-witnessed CPR process from a patient's perspective through 360° virtual reality and 2D video within…
- Conditions
- Family Witnessed Resuscitation, Empathy Education, Ethics Nursing, Education Nursing
- Trial name
- NCT07692568
- Testing
- 360 Degree Virtual Reality Video, 2D Standard Video
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Kocaeli Sağlık ve Teknoloji Üniversitesi
Dental Caries, Insufficient Dental Filling
A Clinical Trial to Compare the Safety and Performance of Two Different Curing Modes in the Direct Filling Therapy in Deciduous Teeth
The overall aim of this clinical investigation is to assess the clinical performance and safety of composite restorations cured with fast curing mode (5 seconds with 2000 mW/cm²) in primary molars.
- Trial name
- NCT07212660
- Testing
- Fast curing mode, Conventional curing mode
- Where
- 2 sites in Switzerland
- Volunteers
- 70 people
- Sponsor
- Ivoclar Vivadent AG
Congenital Heart Disease
Subcostal Transverse Abdominis Plane Block for Epigastric Cardiac Pacemaker Operation
This prospective randomized controlled trial aims to examine the effect of subcostal transverse abdominis plane block on the postoperative pain and opioid consumption in patients (12y≤ age) who will undergo epigastric cardiac…
- Trial name
- NCT04570878
- Testing
- SC TAP, Control
- Where
- South Korea
- Volunteers
- 22 people
- Sponsor
- Seoul National University Hospital
Acne Vulgaris
Effectiveness of Zinc Supplementation With Topical Retinoids in Acne Vulgaris Patients
The study was 8 weeks, randomized, double-blind, placebo-controlled trial to assess the effect of zinc sulphate on symptoms of mild and moderate acne vulgaris in 122 patients. Participants was assessed at baseline, and 8 weeks.
- Trial name
- NCT04899843
- Testing
- Zinc sulphate tablet 20 mg
- Where
- Bangladesh
- Volunteers
- 122 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh