Clinical trials: CPAP
Premature Birth
A Study to Evaluate the Efficacy of Seattle-PAP for the Respiratory Support of Premature Infants
This study is designed to test the hypothesis that among infants born at less than 30 weeks, weighing less than 1500 g at delivery, and receiving initial respiratory support non-invasively or on invasive respiratory support and…
- Trial name
- NCT03085329
- Testing
- Seattle-PAP, Conventional bubble nasal CPAP
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Seattle Children's Hospital
RDS of Prematurity
NIV Strategies for RDS in Preterm Infants. NIV (Non Invasive Ventilation), RDS (Respiratory Distress Syndrome)
The purpose of this study is to determine whether two different strategies of Non Invasive Ventilation (NIV) have different effect on length and failure of NIV support in preterm infants with respiratory distress syndrome (RDS).
- Trial name
- NIV (NCT02259400)
- Testing
- NSIPPV, BiPAP
- Volunteers
- 280 people
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico "G. Martino"
Pompe Disease
CPAP for Infantile Pompe Disease
Patients with infantile onset Pompe disease will be trained with continuous positive airway pressure to see if hypernasality can be improved.
- Trial name
- NCT02405624
- Testing
- continuous positive airway pressure
- Where
- Taiwan
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Infant, Premature, Diseases, Respiratory Distress Syndrome
Functional Residual Capacity During Different Levels of High-flow in Preterm Infants
Although there is a widespread use of HighFlow therapy around the world, there is still uncertainty about the most appropriate initial HighFlow level after nasal continuous positive airway pressure therapy.
- Trial name
- FunkFlow (NCT05237622)
- Testing
- High Flow
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- University of Zurich
Down Syndrome
Role of Sleep Apnea in the Neuropsychological Function in Down Syndrome People
This is the first study about Neuropsychological function and OSAS in Taiwan. Although the correlation between OSAS and neuropsychological abnormalities had been reported, it is worth to understand more about the detailed domains…
- Trial name
- NCT03267602
- Testing
- CPAP
- Volunteers
- 45 people
- Sponsor
- National Taiwan University Hospital
Pneumonia, Ventilator-Associated, Pneumonia, Bacterial
CTTI Risk Factors for HABP/VABP Study
The purpose of this study is to better define the intensive care unit population at highest risk for developing Hospital-Acquired and Ventilator-Associated Bacterial Pneumonia (HABP/VABP).
- Conditions
- Pneumonia, Ventilator-Associated, Pneumonia, Bacterial, Pneumonia, Hospital-Acquired
- Trial name
- PROPHETIC (NCT02689531)
- Where
- 15 sites in United States
- Volunteers
- 7,530 people
- Sponsor
- Duke University
Neonatal, Premature Birth
Extending CPAP Therapy in Stable Preterm Infants to Increase Lung Growth and Function
This is a study to see if an extra 2 weeks of continuous positive airway pressure (CPAP) in stable preterm infants in the neonatal intensive care unit (NICU) can cause increased lung growth and lung function in the infants as…
- Conditions
- Neonatal, Premature Birth, Respiratory Distress Syndrome
- Trial name
- NCT04295564
- Testing
- Additional 2 weeks of CPAP
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Cynthia McEvoy
Respiratory Distress Syndrome
n-CPAP Versus n-BiPAP and NIPPV for Postextubation in RDS in Preterms
non-invasive ventilation in preterms complaining from RDS a randomized, controlled trial to compare between capap, n-bipap and NIPPV
- Trial name
- NCT01770925
- Testing
- N-CPAP, n-BiPAP, NIPPV
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Anesthesia
Lung Recruitment and Postoperative CPAP
General anesthesia lowers FRC thereby promoting airway closure and absorption atelectasis. Alveolar recruitment manoeuvers recruit collapsed alveoli, increase gas exchange, and improve arterial oxygenation.
- Trial name
- LRvsCPAP (NCT02502279)
- Testing
- Engström Datex-Ohmeda ICU Ventilator, Postoperative CPAP mask
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Hypovolemia
Lung Recruitment Maneuver for Predicting Fluid Responsiveness in Children
Lung recruitment maneuver induces a decrease in stroke volume, which is more pronounced in hypovolemic patients. The authors hypothesized that the changes of dynamic variables through lung recruitment maneuver could predict…
- Trial name
- NCT03184961
- Testing
- lung recruitment maneuver
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Preterm Birth, Respiratory Distress Syndrome
Sustained Lung Inflation and Pulmonary Mechanics in Preterm Infant
Lung protection should start in the delivery room where, from the first breaths, the preterm infant can be helped to clear the lung fluid and to recruit alveolar spaces and establish the functional residual capacity (FRC).
- Conditions
- Preterm Birth, Respiratory Distress Syndrome, Lung Diseases
- Trial name
- NCT02493920
- Testing
- Sustained lung inflation, mask using a T-piece system (Fabian,Acutronic Medical Systems AG, Switzerland).
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Preterm Infants, Nasal Continuous Positive Airway Pressure
Effect of Therapeutic Touch and Mother's Voice on Pain and Comfort Level During Nasal CPAP Application
Aim: This study was conducted to evaluate the effects of Therapeutic Touch and Mother's Voice on pain and comfort levels of preterm infants during nasal CPAP application.
- Conditions
- Preterm Infants, Nasal Continuous Positive Airway Pressure, Pain Management
- Trial name
- CPAP (NCT05577793)
- Testing
- Mother's Voice, Therapeutic Touch, Mother's Voice +Therapeutic Touch
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Ayşe Belpınar
Asthma
Modulation Of Airway Reactivity With Chronic Mechanical Strain
The purpose of this study is to see if the use of a machine called CPAP will help children with asthma breathe better. CPAP is a machine that produces airflow to help people with breathing problems.
- Trial name
- NCT02396849
- Testing
- Continuous Positive Airway Pressure (CPAP)
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Indiana University
Community Acquired Pneumonia, Bronchiolitis
HVNI vs CPAP in Children With Acute Respiratory Distress
Acute breathing problems are a common reason for children to be admitted to the pediatric intensive care unit, and many of these children need breathing support without a breathing tube.
- Trial name
- P-HVNI-CPAP (NCT07336121)
- Testing
- High Velocity Nasal Insufflation (HVNI), Nasal Continuous Positive Airway Pressure (Nasal CPAP)
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Obstructive Sleep Apnea of Adult
Assessment of Pulmonary Artery Pressure and Right Sided Hemodynamics in Patients With OSA Before and After CPAP TTT
Obstructive sleep apnea (OSA) is a frequent sleep-related breathing disorder with an incidence of 5-20% in the middle-aged population in Europe and Northern America .
- Trial name
- NCT03276611
- Testing
- echocardiograghy
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Intraventricular Hemorrhage
Neonatal Resuscitation With Intact Cord
The purpose of this study is to examine whether providing ventilation during delayed umbilical cord clamping provides greater placental transfusion and improved hemodynamic transition at birth.
- Trial name
- NRIC (NCT02231411)
- Testing
- V-DCC, Delayed cord clamping, Dry and and if apneic initially can stimulate by gently rubbing the back for approximately 30 seconds with warm sterile towels
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Sharp HealthCare
Sleep Apnea, Obstructive, Sleep Apnea Syndromes
Continuous Positive Airway Pressure (CPAP) After Adenotonsillectomy in Children
Obstructive sleep-disordered breathing (SDB) affects 2-3% of children and may lead to problems with nighttime sleep and daytime behavior, learning, sleepiness, and mood.
- Conditions
- Sleep Apnea, Obstructive, Sleep Apnea Syndromes, Child Behavior Disorders, Attention Deficit Disorder With Hyperactivity
- Trial name
- NCT01554527
- Testing
- CPAP treatment, No CPAP treatment
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Michigan
Atelectasis
Continuous Positive Airway Pressure Decreased Lung Collapse During General Anesthesia Induction in Pediatric Patients
Anesthesia-induced atelectasis is a well-known entity observed in approximately 68-100% of pediatric patients undergoing general anesthesia.
- Trial name
- NCT03461770
- Testing
- CPAP
- Where
- Argentina
- Volunteers
- 42 people
- Sponsor
- Hospital Privado de Comunidad de Mar del Plata
Feeding Behavior, Chronic Lung Disease
Pilot Study Comparing Different Modes of Non-invasive Ventilation for the Oral Feeding of Preterm Infants
Preterm infants born before 28 weeks gestation are at risk for lung disease and require oxygen and pressure to keep their lungs open. This usually involves a device called nasal continuous positive airway pressure (nCPAP).
- Trial name
- CHOMP (NCT02055339)
- Testing
- Fisher & Paykel heated humidified high flow nasal cannula, InfantFlow/RAM nasal continuous positive airway pressure
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Mount Sinai Hospital, Canada
Neonatal Respiratory Distress Related Conditions
Oscillatory Versus Non-oscillatory Nasal Continuous Airway Pressure Neonatal Respiratory Support
Controlled randomized trial looking at Standard nasal continuous airway pressure (CPAP) respiratory support versus High Frequency CPAP in neonates who require respiratory support or who are being extubated and require support…
- Trial name
- NCT03711565
- Testing
- Regular Nasal CPAP using a conventional ventilator, High Frequency Nasal CPAP
- Where
- United States
- Sponsor
- University of California, Davis