Clinical trials: Pemetrexed, completed
Vital Pulp Therapy in Primary Teeth
Evaluation of Pulpotomy, Partial Pulpotomy, and Direct Pulp Capping Using Mineral Trioxide Aggregate.
A comparative evaluation for three vital pulp therapy techniques in primary molars using the same material (MTA)
- Trial name
- NCT07333872
- Testing
- pulp capping with MTA
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Delta University for Science and Technology
Patients With Deep Carious Lesions
Comparative Study Between Biodentine and Mineral Trioxide Aggregate in Direct Pulp Capping
Comparative study between Biodentine and MTA in direct pulp capping of deeply carious teeth.
- Trial name
- NCT02803528
- Testing
- Biodentine, MTA
- Where
- Syria
- Volunteers
- 30 people
- Sponsor
- Damascus University
Malignant (Pleural) Mesothelioma
Dendritic Cell-based Immunotherapy Combined With Low-dose Cyclophosphamide in Patients With Malignant Mesothelioma
Earlier the investigators determined the safety and feasibility of tumor lysate-pulsed dendritic cells as therapeutic adjuvants in mesothelioma patients.
- Trial name
- PMR-MM-002 (NCT01241682)
- Testing
- DC + CTX
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Erasmus Medical Center
Pulpitis - Irreversible, Tooth Decay
Efficacy of PRF and MTA as Compared to Calcium Hydroxide for Pulpotomy in Human Irreversibly Inflamed Permanent Teeth
Of all the various pulpotomy medicaments that have been studied till to date, three agents have been selected for this study to compare their efficacy.
- Trial name
- NCT05266859
- Testing
- Calcium hydroxide, MTA, PRF
- Where
- Pakistan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Liaquat College of Medicine and Dentistry
Periapical Periodontitis
Biodentine as an Apical Plug in Immature Permanent Molars
Following the randomization procedure, patients will be divided into 2 groups (12 immature molars in each group): Group I will be treated with MTA as apical plug, whereas group II will be treated with Biodentine as apical plug.
- Trial name
- NCT05719987
- Testing
- Biodentine, MTA
- Where
- Syria
- Volunteers
- 24 people
- Sponsor
- Damascus University
Pulp Necrosis
Evaluation of Biodentine and Mineral Trioxide Aggregate in Revascularization of Non Vital Immature Anterior Teeth
the object of this study is to evaluate clinically and radiographically the effect of using Biodentine and Mineral Trioxide Aggregate as coronal plug materials in revascularization of non-vital immature teeth
- Trial name
- NCT03589560
- Testing
- Biodentine, Mineral Trioxide Aggregate
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Acne
Use of Mobile Teledermatology in the Care of Acne Patients
The purpose of the present study is to determine whether a mobile teledermatology care model can achieve better clinical outcomes as compared to conventional, outpatient care for the management of severe acne treated with…
- Trial name
- Teleacne (NCT01399970)
- Testing
- Mobile Teleconsultation Arm (MTA), Outpatient Consultation Arm (OCA)
- Where
- Austria
- Volunteers
- 69 people
- Sponsor
- Medical University of Graz
Unspecified Childhood Solid Tumor, Protocol Specific
Pemetrexed Disodium in Treating Young Patients With Recurrent Solid Tumors
RATIONALE: Drugs used in chemotherapy, such as pemetrexed disodium, use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00070473
- Testing
- pemetrexed disodium
- Where
- 20 sites in United States, Canada
- Volunteers
- 33 people
- Sponsor
- Children's Oncology Group
Symptomatic Irreversible Pulpitis (SIP)
Clinical and Radiographic Evaluation of Laser Assisted Pulpotomy in Immature Permanent Molars With Symptoms Indicative of Irreversible Pulpitis
The goal of this clinical trial is to assess the clinical and radiographic success rate of Laser pulpotomy procedure done in immature permanent molars with symptoms indicative of irreversible pulpitis..
- Trial name
- NCT07704463
- Testing
- Application of 660 nm diode laser, Application of 970 nm diode laser + MTA, Conventional MTA pulpotomy (control group)
- Where
- Egypt
- Volunteers
- 57 people
- Sponsor
- Alexandria University
Vital Pulp Therapy
Vital Pulp Therapy With Different Materials for Young Permanent Teeth
This study will be conducted to: Evaluate clinically and radiographically apexogenesis in immature permanent molars using: 1. Calcium Hydroxide. 2. MTA. 3. Laser. 4. Laser combined with MTA.
- Trial name
- NCT05498337
- Testing
- calcium hydroxide, MTA, Diode Laser
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Pulp Exposure, Dental
Pulpotomy Technique Preserving Vitality of Traumatized Anterior Permanent Immature Teeth
Aim of the study: To compare the clinical and radiographic outcomes of mineral trioxide aggregate (MTA) and Biodentine as vital pulp therapy materials (pulpotomy) preserving the vitality of traumatized immature anterior permanent…
- Trial name
- NCT03838068
- Testing
- Biodentine, mineral trioxide aggregate, cervical pulpotomy
- Where
- Egypt
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Gihan M Abuelniel ,PhD
Extensively Decayed Primary Molars
Efficacy of Totalfill® and ProRoot MTA® as Pulpotomy Agent in Primary Molars
An experimental prospective double-blind, randomized clinical trial (RCT) with parallel design. To evaluate the outcome of using 2 pulpotomy agents: Totalfill® as study group and mineral trioxide aggregate (MTA®) as a control.
- Trial name
- NCT05149651
- Testing
- Totalfill, MTA
- Where
- Belgium
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Ghent
Pulp Necrosis, Apexification
Evaluation the Effect of Using of Apical Matrix With Apexification Procedure on Apical Healing of Necrotic Immature Teeth
This study was conducted to evaluate the effect of the use of apical matrix, with Mineral Trioxide Aggregate (MTA) or calcium hydroxide Ca(OH)2 Apexification on apical healing and calcific barrier formation of immature teeth with…
- Trial name
- NCT03849222
- Testing
- Apexification, MTA, Ca(OH)2
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Direct Pulp Capping in Primary Teeth
DPC in Primary Molars.
To evaluate clinical and radiographical outcomes of direct pulp capping using calcium hydroxide (CH), mineral trioxide aggregate (MTA), and premedicated direct pulp capping (PDPC) with formocresol (FC) in primary teeth.
- Trial name
- NCT05222243
- Testing
- Direct pulp capping with calcium hydroxide, Direct pulp capping with MTA, Direct pulp capping with Formocresol
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Decayed Primary Molars
Partial Versus Complete Pulpotomy Using Three Different Materials in Primary Molars: a Clinical Study
The purposes of the study to compare partial pulpotomy versus complete pulpotomy in primary molars using three different materials (Formocresol, MTA, Theracal LC) .
- Trial name
- NCT05190783
- Testing
- Formocresol, MTA, TheraCal
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Endometrial Cancer
Pemetrexed Disodium in Treating Patients With Persistent or Recurrent Endometrial Cancer
RATIONALE: Drugs used in chemotherapy such as pemetrexed disodium work in different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00087100
- Testing
- pemetrexed disodium
- Where
- 23 sites in United States
- Volunteers
- 51 people
- Sponsor
- Gynecologic Oncology Group
Malignant Mesothelioma
Pemetrexed Disodium and Cisplatin Followed By Surgery and Radiation Therapy in Treating Patients With Malignant Pleural Mesothelioma
RATIONALE: Drugs used in chemotherapy, such as pemetrexed disodium and cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00227630
- Testing
- cisplatin, pemetrexed disodium, adjuvant therapy
- Where
- 8 sites in Belgium, Italy and 2 more
- Volunteers
- 59 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Osteosarcoma, Medulloblastoma
A Study of Pemetrexed in Children With Recurrent Cancer
To determine the response rate of pemetrexed given every 21 days for the treatment of children with relapsed or refractory osteosarcoma, Ewing's sarcoma/peripheral primitive neuroectodermal tumors (PNET), rhabdomyosarcoma…
- Conditions
- Osteosarcoma, Medulloblastoma, Sarcoma, Ewing's, Neuroblastoma (Measurable Disease)
- Trial name
- NCT00520936
- Testing
- pemetrexed
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Eli Lilly and Company
Cervical Intraepithelial Neoplasia, Uterine Neoplasms
A Trial for Patients With Advanced/Recurrent Cervical Cancer
This phase II trial is studying the antitumor activity of single agent pemetrexed 900mg/m2 IV over 10 minutes in patients with recurrent cervical cancer.
- Conditions
- Cervical Intraepithelial Neoplasia, Uterine Neoplasms, Genital Neoplasms, Female
- Trial name
- NCT00190983
- Testing
- Pemetrexed
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Eli Lilly and Company
Advanced Solid Tumors
An Extension Protocol for Subjects Who Were Previously Enrolled in Other Tivantinib (ARQ 197) Protocols
This is an extension study that will allow participants to continue to receive study therapy when the original studies into which they were enrolled have reached their designated end-dates.
- Trial name
- NCT01178411
- Testing
- Tivantinib, Anti-Cancer Combination Therapy
- Volunteers
- 60 people
- Sponsor
- ArQule, Inc., a subsidiary of Merck Sharp & Dohme LLC, a subsidiary of Merck & Co., Inc. (Rahway, NJ USA)