Clinical trials: sponsored by Brown University
Problematic Phone Use Behavior, Depression
The Mindful Smartphone Use Study
The goal of this clinical trial is to understand the feasibility and acceptability on a mindfulness-based intervention to address co-existing smartphone addiction and psychological distress among adolescents ages 13-19…
- Conditions
- Problematic Phone Use Behavior, Depression, Anxiety
- Trial name
- NCT07892807
- Testing
- Mindwire
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Brown University
Suicide, Attempted
Skills to Enhance Positivity in Suicidal Youth
This is a Hybrid Type I Effectiveness-Implementation design. Specifically, this study proposes to test the effectiveness of STEP in reducing suicidal events and ideation in 216 adolescents, admitted to inpatient psychiatric care…
- Trial name
- STEP (NCT04994873)
- Testing
- STEP, Enhanced TAU
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- Brown University
Health Behavior, Wellness, Psychological
Teen Health Choices & Wellness
The goal of this observational study is to learn more about changes in health, wellness, and substance-use behaviors as teenagers get older.
- Conditions
- Health Behavior, Wellness, Psychological, Substance Use
- Trial name
- THC&W (NCT06822569)
- Testing
- Cue reactivity paradigm
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Brown University
Sickle Cell Anemia in Children, Sickle Cell Disease
Promoting Utilization and Safety of Hydroxyurea Using Precision in Africa
Sickle cell anemia (SCA) is among the world's most common and devastating blood disorders, affecting more than 300,000 newborns per year.
- Trial name
- PUSHUP (NCT05285917)
- Testing
- Hydroxyurea
- Where
- Angola
- Volunteers
- 400 people
- Sponsor
- Brown University
Maternal Depression
Improving Preschool Outcomes by Addressing Maternal Depression in Head Start
Within a research network of Head Start centers in Massachusetts, an efficacy trial of a stepped-care intervention (SCI) to address maternal depression, using intervention components that both prevent depression and help those in…
- Trial name
- NCT04092010
- Testing
- Problem-solving education (PSE), Engagement sessions, Usual care
- Where
- United States
- Volunteers
- 388 people
- Sponsor
- Brown University
Substance Use Disorders
Substance Use Prevention for Youth With Parents in Recovery
Risk for substance use disorder (SUD) begins early in the life course. Although preventing and decreasing illicit and nonmedical drug use among youth is an urgent public health priority, there are currently few evidence-based…
- Trial name
- NCT05397691
- Testing
- Modified Family Talk, Control-like parameter estimation
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Brown University
Pain, Postoperative, Substance Use
iPAWS: Improving Pain Management After Wisdom Tooth Extraction Surgery
This is a clinical trial that will evaluate the feasibility and acceptability of a virtual brief program for adolescents and young adults undergoing wisdom tooth extraction and their parents.
- Trial name
- iPAWS (NCT07731295)
- Testing
- iPAWS, Educational Materials
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Brown University
Suicide, Suicide Awareness
Hand in Hand, We Rise (Xie Shou Gong Jin)
This study aims to conduct a cluster randomized controlled trial to assess the feasibility of implementing the "Hand in Hand, We Rise" (Xie Shou Gong Jin) multi-stakeholder collaborative school-based suicide prevention program in…
- Conditions
- Suicide, Suicide Awareness, Mental Health, Suicide Prevention
- Trial name
- NCT07722455
- Testing
- Xie Shou Gong Jin, Regular psychoeducation class
- Where
- China
- Volunteers
- 1,680 people, healthy volunteers welcome
- Sponsor
- Brown University
Alcohol Use Disorder
Supporting Adolescent Alcohol Treatment With Computer-Based ('Path180') Skills Training
This 8-week clinical trial will test a computer-based skills training program called Path180 with 112 adolescents aged 13 to 19 who are receiving mental health counseling or outpatient substance use treatment.
- Trial name
- NCT07713251
- Testing
- Path180
- Where
- United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Brown University
Suicidal Ideations, Suicidal Behaviors
Technology-assisted Methods to Advance Suicide Prevention Among Youth in Colombia
This study will investigate a multi-level approach that applies technology-assisted methods to reduce suicidal thoughts and behaviors (SIB) and promote mental health among Colombian youth: (a) digital platform for youth; (b)…
- Conditions
- Suicidal Ideations, Suicidal Behaviors, Depression, Anxiety, Well-being
- Trial name
- NCT06651554
- Testing
- Digital Platform Intervention
- Where
- Colombia
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Brown University
Prenatal Exposure Delayed Effects
Nutrition and Inflammation in Pregnancy: Impacts on Early Human Brain Development in Ethiopia
The goal of this observational child follow-up study is to examine the effects of prenatal nutrition and infection management interventions on long-term child neurodevelopment.
- Trial name
- NCT06296238
- Where
- Ethiopia
- Volunteers
- 463 people, healthy volunteers welcome
- Sponsor
- Brown University
Mental Health
Advancing mHealth-supported Adoption and Sustainment of an Evidence-based Mental Health Intervention in Sierra Leone
This study will examine a new implementation strategy for the Youth Readiness Intervention (YRI), an evidence-based mental health intervention.
- Trial name
- NCT05737667
- Testing
- Youth Readiness Intervention (YRI)
- Where
- Sierra Leone
- Volunteers
- 1,454 people, healthy volunteers welcome
- Sponsor
- Brown University
Intervention, Control
Testing the Efficacy of Safe South Africa
In this study, investigators will examine the efficacy of Safe South Africa, a behavioral intervention that is developmentally- and gender-tailored to prevent human immunodeficiency virus (HIV) and intimate partner violence (IPV)…
- Trial name
- NCT06750107
- Testing
- Safe South Africa
- Where
- South Africa
- Volunteers
- 836 people, healthy volunteers welcome
- Sponsor
- Brown University
Alzheimer Disease or Associated Disorder
Coordinated Emergency Department Transitions
The goal of this observational study is to learn the feasibility, acceptability, appropriateness, and adherence to a case management intervention.
- Trial name
- NCT06933849
- Testing
- Structured case management
- Where
- United States
- Volunteers
- 1,376 people
- Sponsor
- Brown University
Diet, Healthy
Using Family-Based Approaches to Improve Healthy Eating for Southeast Asian Children
This small scale healthy eating study provides Southeast Asian families with children ages 6 to 11 with a family-based nutrition education, one-on-one interviews to help with motivation to eat health, text messaging, and coupons…
- Trial name
- NCT05817838
- Testing
- Financial Incentives, Financial Incentives and Multilevel Multicomponent, School Engagement
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Brown University
Opioid Overdose, Drug Overdose
Preventing Overdose Using Information and Data From the Environment
The objectives of this project are to leverage surveillance data to predict future overdose outbreaks, and to evaluate the impact of a randomized, statewide, community-level intervention trial to target overdose prevention…
- Trial name
- PROVIDENT (NCT05096429)
- Testing
- PROVIDENT
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Brown University
Dementia
Effect of an Advance Care Planning Intervention
The intervention being studied is an advance care planning intervention. The trial has two arms: usual care and information arm.
- Trial name
- NCT04852055
- Testing
- Advance Care Planning Video
- Where
- United States
- Volunteers
- 2,364 people
- Sponsor
- Brown University
Neurophysiologic Maturation
Neurophysiologic Maturation Index for Late Preterm Infants
Late preterm infants contribute to significant neonatal intensive care unit health care resource utilization because of their sheer numbers. Determinants of the length of hospitalization (LOH) in this population are understudied.
- Trial name
- NEMO Project (NCT02156817)
- Testing
- Amplitude integrated electroencephalogram, Cardiorespiratory signal acquisition
- Where
- 3 sites in United States, Canada
- Volunteers
- 26 people
- Sponsor
- Brown University
Sexual Behavior, Depression
Our Family Our Future: Acceptability and Feasibility Study of a Family Prevention Program for HIV Risk and Depression
The purpose of this study is to assess the feasibility and acceptability of a family-based preventive intervention designed to reduce sexual risk behaviors and depressive symptoms among South African adolescents and their…
- Trial name
- NCT02432352
- Testing
- Our Family Our Future
- Where
- South Africa
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Brown University
Sexual Behavior, Intimate Partner Violence
Integrated Prevention of HIV Risk and Intimate Partner Violence Among Adolescents in South Africa
The purpose of this study is to test the feasibility and acceptability of Safe South Africa, an integrated intervention for preventing HIV and Intimate Partner Violence perpetration for male adolescents 15-17 years of age.
- Trial name
- NCT03179982
- Testing
- Safe South Africa
- Where
- South Africa
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brown University