Clinical trials: sponsored by Menoufia University
Bilateral Inguinal Hernia Repair, Open Upper Abdominal Surgeries
Ultrasound-guided Quadratus Lumborum Block Versus Erector Spinae Plane Block for Postoperative Analgesia in Children Undergoing Elective Open Lower Abdominal Surgeries
To compare the postoperative analgesic efficacy of ultrasound-guided Quadratus Lumborum Block (anterior approach) versus Erector Spinae Plane Block (T10-T12 level), both performed bilaterally with 0.25% bupivacaine (0.5 mL/kg per…
- Trial name
- NCT07853586
- Testing
- ultrasound guided anterior oudratus lumborum block, Ultrasound guided erector spinae plane block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University
Autoimmune Encephalitis (AE)
Plasma Exchange in Pediatric Autoimmune Encephalitis
The aim of the study will be to compare the efficacy of daily plasma exchange (PLEX) versus alternate-day PLEX in achieving a favorable functional outcome in children with autoimmune encephalitis.
- Trial name
- PE/AIE (NCT07707739)
- Testing
- Plasma exchange (PE)
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Menoufia University
Treatment of Non-monosymptomatic Nocturnal Enuresis
Efficacy of Mirabegron for Treatment of Non-monosymptomatic Nocturnal Enuresis in Children
This phase 3 clinical trial will compare use of individual treatment with mirabegron or desmopressin and their combination for treatment of non-monosymptomatic nocturnal enuresis in children
- Trial name
- NCT07398261
- Testing
- Mirabegron 25 MG
- Where
- Egypt
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Prophylactic, Anticoagulation
Prophylactic Anticoagulation for Central Venous Line Insertion in Critically Ill Children
This will be a Prospective, randomized, open- label, parallel-group, center trial, which will include 80 of Children which will be admitted at Pediatric Intensive Care Unit (PICU) of Menoufia university Hospital from August 2026…
- Trial name
- NCT07710482
- Testing
- Enoxaparin
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Severe Sepsis
Plasma Exchange in Children With Severe Sepsis and Septic Shock
The aim of the study will be to to evaluate whether therapeutic plasma exchange (TPE) reduces mortality in critically ill children with severe sepsis or septic shock compared to the standard care of sepsis alone.
- Trial name
- PE/Sepsis (NCT07706413)
- Testing
- Plasma exchange (PE)
- Where
- Egypt
- Volunteers
- 22 people
- Sponsor
- Menoufia University
Urethral Stricture, Anterior, Urethral Stricture Disease
Outcomes of Double-face Augmentation Urethroplasty
Combined dorsal and ventral onlay augmentation for bul¬bar urethral reconstruction. Nontraumatic near-obliterative bulbar urethral strictures (BUS) of <2 cm in length can be managed with non-transecting anastomotic bulbar…
- Trial name
- BMG (NCT07436819)
- Testing
- Double-face augmentation urethroplasty
- Where
- 2 sites in Egypt
- Volunteers
- 30 people
- Sponsor
- Menoufia University
Quadratus Lumborum Block, Transversus Abdominis Plane Block
Quadratus Lumborum Block, Transversus Abdominis Plane Block, and Erector Spinae Block in Pediatric Abdominal Surgery
The aim of this study is to compare the analgesic efficacy and safety of Quadratus Lumborum (QL), Transversus Abdominis Plane (TAP), and Erector Spinae Plane (ESP) blocks in pediatric abdominal surgery.
- Conditions
- Quadratus Lumborum Block, Transversus Abdominis Plane Block, Erector Spinae Plane Block, Pediatric
- Trial name
- NCT07850596
- Testing
- Quadratus lumborum (QL) block, Transversus abdominis plane (TAP) block, Erector spinae plane (ESP) block
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University
Congenital Hypothyroidism
Levothyroxine Dosing in Neonatal Congenital Hypothyroidism
This randomized controlled trial compared high-dose and moderate-dose levothyroxine as initial therapy for neonates with primary congenital hypothyroidism.
- Trial name
- CH-LT4 (NCT07754370)
- Testing
- Levothyroxine
- Where
- Egypt
- Volunteers
- 101 people
- Sponsor
- Menoufia University
Hip Osteoarthritis, Hip Arthroplasty Replacement
Virtual Reality for Intraoperative Anxiolysis and Postoperative Agitation in Elderely Hip Arthroplasty Patients
This study evaluates the effectiveness of Virtual Reality (VR) as a non-pharmacological intervention to reduce intraoperative anxiety and postoperative agitation in elderly patients undergoing elective hip arthroplasty under…
- Conditions
- Hip Osteoarthritis, Hip Arthroplasty Replacement, Emergence Delirium, Anesthesia, Emergence Agitation
- Trial name
- VR (NCT07705451)
- Testing
- immersive virtual reality, standard sedation
- Volunteers
- 40 people
- Sponsor
- Menoufia University
Denture, CAD/CAM
Effect of Certain Denture Disinfectants on Surface Topography, Microhardness and Dimensional Stability of CAD/CAM Milled Polymethyl Methacrylate and Polyether Ether Ketone Denture Base Materials
This study aims to evaluate and compare the influence of different denture cleansing methods using 1% sodium hypochlorite solution, 0.2% chlorhexidine solution and effervescent alkaline peroxide tablet solution -according to…
- Conditions
- Denture, CAD/CAM, Stability, PEEK
- Trial name
- NCT07672847
- Testing
- M0 group, M1 group : PMMA+ Sodium hypochlorite, M2 group: PMMA+ Chlorhexidine
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Menoufia University
Nonfunctioning Kidney, Renal Cell Carcinoma (RCC)
Laparoscopic Versus Open Nephrectomy : Clinical Effectivness and Cost Analysis
To evaluate and compare clinical effectiveness (operative time, blood loss, hospital stay, complications and etc) and cost analysis' between laparoscopic nephrectomy and open nephrectomy .
- Trial name
- NCT07461090
- Testing
- open or laparoscopic nephrectomy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Major Depressive Disorder (MDD), SCHIZOPHRENIA 1 (Disorder)
Transcranial Direct Current Stimulation (tDCS) in Different Psychiatric Disorders
The goal of this clinical trial is to evaluate the efficacy and safety of transcranial direct current stimulation (tDCS) in reducing core symptoms of different psychiatric disorders using validated clinical scales.
- Conditions
- Major Depressive Disorder (MDD), SCHIZOPHRENIA 1 (Disorder), Obsessive-Compulsive Disorder, Generalized Anxiety Disorder
- Trial name
- Transcranial (NCT07452835)
- Testing
- tDCS Parameters
- Where
- Egypt
- Volunteers
- 320 people
- Sponsor
- Menoufia University
Edentulous Jaw
Monolithic Zirconia Full-Arch Rehabilitation Using Digital Technology
20 edentulous patients presented for full-arch rehabilitation and was managed using a motion-integrated, fully digital workflow that combined the M-4 protocol in the maxilla with the All-on-4 concept in the mandible.
- Trial name
- NCT07369583
- Testing
- Motion-Integrated, Fully Digital Full-Arch Implant Rehabilitation Combining Maxillary M-4 and Mandibular All-on-4 Protocols with Monolithic Zirconia Prostheses
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Nocturnal Enuresis in Children, Desmopressin
Ginkgo Biloba vs Desmopressin in Treatment of Children With Monosymptomatic Nocturnal Enuresis
the efficacy of Ginkgo Biloba versus desmopressin in treatment of children with monosymptomatic nocturnal enuresis
- Conditions
- Nocturnal Enuresis in Children, Desmopressin, Monosymptomatic Nocturnal Enuresis
- Trial name
- NCT06771128
- Testing
- Ginkgo Biloba oral tablet, Desmopressin Acetate 0.2 mg Tablets
- Where
- Egypt
- Volunteers
- 398 people
- Sponsor
- Menoufia University
Prostate Cancer
Cognitive and Fusion Prostatic Biopsy
The goal of this study is to compare two different prostate biopsy techniques used to detect prostate cancer. These techniques are cognitive-targeted biopsy (CTB) and magnetic resonance imaging-ultrasound fusion-targeted…
- Trial name
- CTB-FTB (NCT07306741)
- Testing
- Cognitive-targeted prostate biopsy
- Where
- 2 sites in Egypt
- Volunteers
- 80 people
- Sponsor
- Menoufia University
Erector Spinae Plane Block, Children
Erector Spinae Plane Block for Children Undergoing Thoracoscopic Sympathectomy
This study aims to evaluate the influence of ultrasound-guided erector spinae plane block on postoperative pain and diaphragmatic dysfunction in pediatric patients undergoing thoracoscopic sympathectomy.
- Conditions
- Erector Spinae Plane Block, Children, Thoracoscopic Sympathectomy
- Trial name
- NCT06984874
- Testing
- Erector spinae plane block, General anesthesia
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Menoufia University
TURP(Transurethral Resection of Prostate), BPH (Benign Prostatic Hyperplasia)
Corkscrew Technique: A Novel Modification in Transurethral Resection of Large Prostate (60-100 g) Optimizing Resection Efficacy and Safety: A Double-blind Randomized Controlled Trial
Transurethral resection of the prostate (TURP) is still the gold standard for surgical management of enlarged prostate. However, many techniques and minimally invasive procedures are now in the comparative track with Bipolar…
- Conditions
- TURP(Transurethral Resection of Prostate), BPH (Benign Prostatic Hyperplasia), Prostate
- Trial name
- NCT06901115
- Testing
- Nesbit technique, Corkscrew technique
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Menoufia University
Prostatic Cancer
Fusion Versus Cognitive MRI Targeted Prostatic Biopsy
The aim of the present study is to compare the accuracy of Magnetic resonance imaging targeted (fusion) versus cognitive prostatic biopsy in biopsy-naïve suspected cancer prostate patient
- Trial name
- NCT05969704
- Testing
- MRI fusion targeted prostatic biopsy, MRI cognitive targeted prostatic biopsy
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Menoufia University
Enuresis, Nocturnal
Ginko Biloba Versus Desmopressin in Treatment of Children With Monosymptomatic Nocturnal Enuresis
Bedwetting among children is a common disorder, affecting 30% at age 4, 10% at age 6, 3% at age 12, and 1% at age.Untreated, the spontaneous cure rate is about 15% a year.
- Trial name
- NCT06772584
- Testing
- Desmopressin Acetate 0.2 mg Tablets, Ginkgobiloba
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Ureteric Stone
Ideal Time of Stenting Prior to Ureteral Access Sheath for Stone Disease
The miniaturization of endourological instruments and improvements in laser lithotripsy have revolutionized the approach to renal stones .
- Trial name
- NCT06761378
- Testing
- Renal stent, Flexible uretroscopy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Menoufia University