Clinical trials: sponsored by Tang-Du Hospital
Healthy Volunteers
Multi-Field-Strength MRI Brain Atlas Construction in Healthy Chinese Population
This prospective imaging study aims to construct a multi-field-strength magnetic resonance imaging (MRI) brain atlas for healthy Chinese adults.
- Trial name
- NCT07786233
- Testing
- Multi-Field-Strength Brain MRI
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Knee Joint
Feature Analysis of Knee Joint Magnetic Resonance Imaging Based on Artificial Intelligence
This retrospective observational study aims to investigate imaging features of the knee joint on magnetic resonance imaging (MRI) using artificial intelligence (AI)-based image analysis.
- Trial name
- NCT07784686
- Where
- China
- Volunteers
- 9,500 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Intracerebral Hemorrhage, Stroke-Associated Pneumonia (SAP)
An Open-Label, Dose-Escalation Study on the Safety, Tolerability and Preliminary Efficacy for Preventing SAP by Intravenous Pump-Delivered Propranolol in Patients With ICH
This is an open-label, dose-escalation study on the safety, tolerability and preliminary efficacy for preventing stroke-associated pneumonia of propranolol in patients with intracerebral hemorrhage.
- Trial name
- PROCHASE-DoE (NCT07528235)
- Testing
- Intravenous Pump-Delivered Propranolol
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Tang-Du Hospital
Patients With Suspected Non-small Cell Lung Cancer (NSCLC) at Clinical Stage T1
Anesthesia Comparison in Early-stage Small NSCLC: A Multicenter RCT
This study is a prospective, randomized, controlled study, which intends to enroll patients with suspected early-stage NSCLC (non-small cell lung cancer) with a diameter of ≤ 3 cm as research subjects.
- Trial name
- NCT07327736
- Testing
- Non-intubated video-assisted thoracic surgery with spontaneous breathing (NIVATS)
- Volunteers
- 410 people
- Sponsor
- Tang-Du Hospital
Non-small Cell Lung Cancer
A Study to Prospectively Validate Blood Markers Associated With Differences in Efficacy of Neoadjuvant Therapy for NSCLC
This study utilized a prospective cohort design. It is proposed to analyze the serum of NSCLC patients treated with chemotherapy combined with immunotherapy, and chemotherapy alone, starting from liquid biopsy technique and…
- Trial name
- NCT06503042
- Testing
- Chemotherapy combined with immunotherapy, Chemotherapy only
- Volunteers
- 100 people
- Sponsor
- Tang-Du Hospital
Glioma
Development and Validation of a Deep Learning-Based Survival Prediction Model for Pediatric Glioma Patients: A Retrospective Study Using the SEER Database and Chinese Data
Accurately predicting the survival of pediatric glioma patients is crucial for informed clinical decision-making and selecting appropriate treatment strategies.
- Trial name
- NCT06199388
- Testing
- Survival state
- Where
- China
- Volunteers
- 9,532 people
- Sponsor
- Tang-Du Hospital
Postoperative Complications, Morality
Postoperative Complications and Mortality With In-Hospital COVID-19 Omicron Infection After Surgery
Postoperative complications and mortality in patients with COVID-19 Omicron infection who have undergone specialized thoracic surgery are scarce.
- Trial name
- NCT06040606
- Testing
- In-Hospital COVID-19 Omicron Infection after surgery
- Where
- China
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Social Media, Mental Health Disorder
The Impact of Shallow Reading in Social Media
Social media is pervasively used in our life. There is a research hypothesis that the information in social media is "shallow" and the long-term use of it will cause readers' addiction, insomnia, and inability to pay attention…
- Conditions
- Social Media, Mental Health Disorder, Brain Imaging
- Trial name
- NCT05097807
- Testing
- smartphone related behaviors
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Cerebrovascular Disease
Assess the Risk of Cerebrovascular Disease
Intracranial artery stenosis is an important cause of ischemic stroke, but the degree of intracranial artery stenosis is not completely matched with the symptoms of ischemic stroke.
- Trial name
- NCT04443439
- Testing
- GE Discovery MR750 3.0t superconducting MRI
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Tang-Du Hospital
Breast Cancer, Chemo-brain
Assessment of Brain Cognitive Impairment in Breast Cancer
To explore the cognitive impairment caused by chemotherapy and endocrine therapy in premenopausal breast cancer patients and to find biomarkers with early predictive effect on this cognitive impairment by using multimodal…
- Conditions
- Breast Cancer, Chemo-brain, Endocrine Therapy
- Trial name
- NCT05305092
- Testing
- PET/MRI, psychobehavioral tests and questionnaires, serum biomarkers and stool sample
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Neuromyelitis Optica Spectrum Disorder
Rituximab at Low dosE for neuromyelitiS optiCa spectrUm disordEr (RESCUE)
In this research, a prospective, multicenter(Tangdu Hospital of Fourth Military Medical University, Xi'an Gaoxin Hospital of Xi'an Medical College, Xianyang Central Hospital, Baoji Central Hospital, Xi'an Central Hospital, The…
- Trial name
- NCT04256252
- Testing
- Rituximab
- Volunteers
- 108 people
- Sponsor
- Tang-Du Hospital
Brown Fat and Muscle Metabolic, Differential Diagnosis
PET/MRI Study on Changes of Fat and Muscle Metabolism.
False positives for Brown Fat \& Muscle（F\&M） always affect the evaluation of metabolic disease treatment. Recently, using PET/CT，international journals such as Journal of Nuclear Medicine reported that the amount of active brown…
- Trial name
- NCT04334720
- Testing
- Comprehensive treatment of tumor
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Non Small Cell Lung Cancer
A Study to Explore Prognoses of NSCLC Patients Complicated With Oligometastases
An observational study to explore prognoses and clinical treatments of the patients with non-small cell lung cancer complicated with oligometastases
- Trial name
- NCT03427541
- Testing
- Surgeries
- Where
- 10 sites in China
- Volunteers
- 1,000 people
- Sponsor
- Tang-Du Hospital
Non-small Cell Lung Cancer Metastatic
A Study to Evaluate Effectiveness and Safety of Tyrosine Kinase Inhibitors
This is a real-world non-interventional observational study. The study was designed to evaluate the effectiveness and safety of clinical treatments in the patients with advanced non-small cell lung cancer (NSCLC) complicated with…
- Trial name
- NCT03424980
- Testing
- Tyrosine kinase inhibitors
- Where
- 5 sites in China
- Volunteers
- 200 people
- Sponsor
- Tang-Du Hospital
Narcolepsy, REM Sleep Behavior Disorder
Investigation of Clinical Feature and Brain Function in Narcoleptic Patients
This study evaluates the PSG and cerebral metabolism and functions in narcolepsy with/without RBD
- Trial name
- NCT03376568
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Thymic Epithelial Tumor
Preoperative Prediction of of Thymic Epithelial Tumors by Diffusion-Weighted MR Imaging
The aim of this study is to analyze aquaporins expression of thymic epithelial tumors and to compare them with apparent diffusion coefficient(ADC) from ultra-high b-values, and to test a possibility of use of ADCuh to identify…
- Trial name
- NCT03212027
- Volunteers
- 60 people
- Sponsor
- Tang-Du Hospital
Aneurysm, Intracranial, Natural History
The Natural Course of Unruptured Intracranial Aneurysms in a Chinese Cohort
This is a registry study of the natural course of unruptured intracranial aneurysms (UIA). In addition, the investigators will analyze the risk factors for the rupture of the UIA and their joint effect.
- Trial name
- NCT03117803
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Tang-Du Hospital
Subarachnoid Hemorrhage, Aneurysmal
Trial of Prophylactic Decompressive Craniectomy for Poor-grade Aneurysmal Subarachnoid Hemorrhage
Decompressive craniectomy has been reported for the treatment of patients with aneurysmal subarachnoid hemorrhage (aSAH). But no prospective randomised controlled trials have yet been undertaken to confirm its effect.The purpose…
- Trial name
- NCT02995928
- Testing
- Decompressive craniectomy, Best medical treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Tang-Du Hospital
Glioma of Brain
Noninvasively Predicting Gene Status of Glioma
Malignant gliomas are the most common and deadly primary brain tumors in adults. The clinical outcome of patients with glioblastoma depends on key molecular genetic alteration.
- Trial name
- NPGSOG (NCT03102112)
- Testing
- MRI examination
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Tang-Du Hospital
Subarachnoid Hemorrhage, Aneurysmal
Predictive Values of Serum Adiponectin Levels in Aneurysmal Subarachnoid Hemorrhage.
The purpose of this study is to evaluate the predictive value of serum adiponectin levels in aneurysmal subarachnoid hemorrhage patients.
- Trial name
- NCT02814162
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital