Clinical trials: sponsored by Université de Sherbrooke
Diagnosis, Inflammation
Diagnosing Asthma With Clinically Accessible, Non-invasive, and Efficient Tests: a Child-inclusive Translational Investigation
Asthma is a common inflammatory respiratory disease affecting 11% of Canadians, but its diagnosis remains challenging, leading to delays in treatment or overtreatment.
- Conditions
- Diagnosis, Inflammation, Asthma in Children, Asthma
- Trial name
- DIVE 2 (NCT07011394)
- Testing
- FeNO, Blood eosinophil count
- Where
- 3 sites in Canada
- Volunteers
- 123 people
- Sponsor
- Université de Sherbrooke
Fragile X Syndrome
Effect of CANnabidiol on Anxiety and GABAergic Function in Individuals With Fragile-X Syndrome
This study focuses on the therapeutic relevance of the endocannabinoid (eCB) system for the treatment of Fragile-X syndrome (FXS), the primary hereditary cause of autism spectrum disorder (ASD).
- Trial name
- CANAX (NCT06261502)
- Testing
- CBD Oral Solution
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Université de Sherbrooke
Developmental Dysplasia of the Hip (DDH), Congenital Hip Dysplasia
Manual Intervention and Congenital Hip Dysplasia in Infants
Developmental dysplasia of the hip (DDH) is a developmental abnormality of the infant hip in which the acetabulum does not adequately cover the femoral head. Standard conservative treatment commonly includes a Pavlik harness.
- Trial name
- NCT07756814
- Testing
- Manual therapy
- Volunteers
- 30 people
- Sponsor
- Université de Sherbrooke
Developmental Coordination Disorder (DCD)
Therapeutic Climbing for Children With DCD
This study looks at whether therapeutic climbing - indoor climbing activities guided by therapists - can help children with Developmental Coordination Disorder (DCD).
- Trial name
- Climbing TDC (NCT07609563)
- Testing
- CO-OP-based group therapeutic climbing intervention
- Volunteers
- 16 people
- Sponsor
- Université de Sherbrooke
Obesity, Childhood, Lifestyle Intervention
Obesity-fertility Cohort Study: Protocol for the Assessment of Children Aged 6-12 Years and Their Mothers
Maternal preconception obesity and adverse gestational metabolic health increase the risk of childhood obesity in offspring. A group of investigators from Université de Sherbrooke therefore developed a lifestyle intervention…
- Conditions
- Obesity, Childhood, Lifestyle Intervention, Preconception Care
- Trial name
- NCT06402825
- Testing
- Fit-for-Fertility program
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Asthma, Inflammation
PROPULSION SANTE: Inflammometry to Improve the Diagnostic Trajectory in Situations of Suspected Asthma in Children and Adults
The objective of this observational study is to assess the relevance of inflammometry (based on the measurement of fractional exhaled nitric oxide (FeNO) and blood eosinophil count (BEC)) as a tool for prioritizing respiratory…
- Conditions
- Asthma, Inflammation, Asthma in Children
- Trial name
- PROPULSION (NCT06981169)
- Testing
- FeNO, blood sample
- Where
- 3 sites in Canada
- Volunteers
- 1,500 people
- Sponsor
- Université de Sherbrooke
Public Health
Cohort as Part of Undergraduate Medical Studies at the University of Sherbrooke
The main goals of this project are to support the research training of undergraduate medical students at the University de Sherbrooke and promote planning of health services a better knowledge of the prevalence, social, and…
- Trial name
- NCT03928509
- Testing
- No intervention
- Where
- Canada
- Volunteers
- 6,000 people
- Sponsor
- Université de Sherbrooke
Healthy Children
Outdoor Science Education and Child Well-being in Primary Schools: Protocol for a Cluster Randomized Controlled Trial on Learning, Connection to Nature, Eco-anxiety, and Stress
The goal of this randomized controlled trial is to learn if an outdoor science education intervention can improve primary school students' learning and well-being when compared to an indoor classroom-based science education…
- Trial name
- Bio-Explo (NCT07147634)
- Testing
- Outdoor science education, Indoor classroom-based science education
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Anxiety, Pain
Colposcopy Anxiety and the Role of Pre-procedure Nursing Intervention
Colposcopy is essential for the diagnosis and prevention of cervical cancer. However, receiving screening results and being informed of the need to undergo a colposcopic examination are significant sources of anxiety for…
- Trial name
- NCT07092189
- Testing
- Pre-colposcopy counseling by a clinical nurse, Treatment as usual: regular call to schedule the appointment without pre-procedure conseilling
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- Université de Sherbrooke
Patellar Instability
French Version of the Banff Patellar Instability Instrument 2.0
There are several treatment options for patellofemoral instability, but no established guidelines currently exist. An important step toward developing a consensus is to examine the influence of each intervention through the…
- Trial name
- NCT06932900
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- Université de Sherbrooke
Fragile X Syndrome
Effect of CBD on the Brain
This proposal focuses on the therapeutic relevance of the endocannabinoid (eCB) system for the treatment of Fragile-X syndrome (FXS), the primary hereditary cause of autism spectrum disorder (ASD).
- Trial name
- NCT06261450
- Testing
- CBD Oral Solution (eCBD system Target)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Mobile App Use in Resuscitation
A Mobile App For Drug Dosage Calculation In The Context Of Pediatric And Adult Resuscitation: A Cross-Over Randomized Controlled Trial
The purpose of this study is to investigate whether the use of the EZResus app by physicians and nurses reduces medication errors in simulated adult and pediatric resuscitation scenarios compared to the use of standard protocols.
- Trial name
- NCT06804915
- Testing
- simulation
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Université de Sherbrooke
Asthma
Phenotyping Responses to Systemic Corticosteroids in the Management of Asthma Attacks
This observational study compares the phenotypic variability (clinical and biological) in treatment response to systemic corticosteroids according to the blood eosinophil count and FeNO in physician-diagnosed ≥12-year-old…
- Trial name
- PRISMA (NCT05870215)
- Testing
- Visit 1: Clinical exam and questionnaires, Visit 1: Respiratory physiology, Visit 1: Inflammometry
- Where
- Canada
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Premature Birth, Neonatal Hypoxic Conditions
Effects of Vanilla on Hypoxic Intermittent Events in Premature Infants
The purpose of this study is to evaluate the effect of vanilla odor on hypoxic intermittent events in premature infants born between 32.0 and 33.6 weeks of gestational age.
- Trial name
- Vanilla (NCT02630147)
- Testing
- Vanilla scent
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Université de Sherbrooke
End-stage Renal Disease
Usefulness and Acceptability of a Connected Ergocycle for the Elderly in a Clinical Setting
Hospitalizations are harmful to patients. Without a proper intervention, it will lead to a permanent decline in physical function, especially among frail individuals.
- Trial name
- NCT05404633
- Testing
- Ergogycle prototype testing for acceptability
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Anaphylaxis, Biphasic Anaphylactic Reaction
SHARED Study (Saguenay Hospitals Anaphylaxis Rule for Early Discharge)
Anaphylaxis is a potentially fatal condition with a prevalence between 0.05 and 2% in the general population. This is therefore a frequent reason for emergency visits.
- Conditions
- Anaphylaxis, Biphasic Anaphylactic Reaction, Rebound Anaphylactic Reaction
- Trial name
- SHARED (NCT04755881)
- Testing
- Occurence of biphasic reaction following anaphylaxis
- Where
- Canada
- Volunteers
- 191 people
- Sponsor
- Université de Sherbrooke
Attention Deficit Disorder With Hyperactivity, Placebo Effect
Attention and Pain in Children With and Without Attention Deficit and/or Hyperactivity Disorder
In Quebec, there has been an important increase of Attention Deficit Hyperactivity Disorder (ADHD) diagnosis since 2015. ADHD symptoms, related to behavioural and/or concentration difficulties, are very similar to other disorders…
- Conditions
- Attention Deficit Disorder With Hyperactivity, Placebo Effect, Nocebo Effect, Pain
- Trial name
- ADE (NCT04766580)
- Where
- Canada
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Covid19
Minimizing the Effects of COVID-19 Hospitalization With the COVID Rehabilitation Program for the Elderly
Although evidence from the management of other viral respiratory infections suggest that early multidisciplinary rehabilitation could mitigate the adverse effects of the severe form of the illness, and reduce the length of…
- Trial name
- CORE (NCT04771052)
- Testing
- COVID Rehabilitation Program for the Elderly (CORE)
- Where
- 2 sites in Canada
- Volunteers
- 124 people
- Sponsor
- Université de Sherbrooke
Motor Disorders
Using Telerehabilitation to Support Families of Children With Motor Difficulties Aged 3-8 Years Old
Background: Many children (about 1 child out of 20) have motor delays that are sometimes seen as "minor" and are not immediately explained by a specific diagnosis.
- Trial name
- WeCare (NCT04254302)
- Testing
- WECARE web platform
- Where
- Canada
- Volunteers
- 118 people
- Sponsor
- Université de Sherbrooke
Fragile X Syndrome
Metformin in Children and Adults With Fragile X Syndrome
Fragile X Syndrome (FXS) is caused by loss of FMR1 expression on the X chromosome that leads to increased mRNA translation, which results in hyperactivation of ERK (extracellular signal-regulated kinase) and mTORC1 (mechanistic…
- Trial name
- NCT03722290
- Testing
- Metformin
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Université de Sherbrooke