Clinical trials: completed
Ventriculitis, Infectious
Effect of Probiotic and Zinc Supplementations on the Clinical Outcome in Pediatric Patients With Ventriculitis
The aim of the study is to evaluate the effect of non-antibiotic-based supplemental interventions in the management of ventriculitis among pediatric patients.
- Trial name
- NCT06151392
- Testing
- Probiotic Formula, Zinc
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Ain Shams University
Anesthesia, Conduction
Infrared Thermography for Assessment of Caudal Block in Children
Regional analgesia via caudal neuraxial blockade provides pain relief for pediatric patients following urological and lower extremity procedures.
- Trial name
- NCT02907957
- Testing
- FLIR ONE, Regional Anesthesia - Caudal Nerve Block
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Motor Development
Motor Development of Normal Children
The goal of this type of study: observational study is to compare motor development between urban and rural regions in pre-school age children.
- Trial name
- NCT05948176
- Testing
- The Bruininks-Oseretsky Test of Motor Proficiency, Second Edition
- Where
- 2 sites in Egypt
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Cairo University
Unilateral Cerebral Palsy
Evolution of Gait Parameters in Toddlers With Unilateral Cerebral Palsy
This study goal was to assess the evolution of spatio-temporal and kinematic gait parameters in toddlers with unilateral cerebral palsy (UCP) receiving standard rehabilitation during the first 18 months after gait acquisition and…
- Trial name
- NCT07906223
- Testing
- gait analysis
- Where
- Romania
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- National Clinical Center for Neuropsychomotor Recovery for Children Dr. Nicolae Robanescu
Lumbar Degenerative Disease, Lumbar Spondylolisthesis
Perioperative Nutrition Management in Patients Undergoing Open Posterior Lumbar Surgery
Patients undergoing open posterior lumbar fusion surgery often experience postoperative gastrointestinal problems, such as bloating, constipation, and delayed passage of gas and stool, and may be at nutritional risk.
- Conditions
- Lumbar Degenerative Disease, Lumbar Spondylolisthesis, Lumbar Disc Herniation
- Trial name
- NCT07893938
- Testing
- Oral nutritional supplements (ONS), Carbohydrate loading (OCL), 'Probiotics (Bifidobacterium and Lactobacillus triple live capsules)'
- Where
- China
- Volunteers
- 90 people
- Sponsor
- First Affiliated Hospital of Kunming Medical University
Oral Leukoplakia (OL), Oral Squamous Cell Carcinoma (OSCC)
FENDRR and CRNDE With DUSP1 and DMBT1 in Oral Leukoplakia and Oral Squamous Cell Carcinoma
Oral squamous cell carcinoma (OSCC) is the most common cancer of the mouth and is often preceded by oral leukoplakia (OL), a white patch of the oral lining that can turn into cancer.
- Trial name
- NCT07906795
- Where
- Egypt
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Amina Fouad Farag
Becker Muscular Dystrophy, Muscular Dystrophies
Defining Endpoints in Becker Muscular Dystrophy
This is a 24-month, observational study of 50 participants with Becker muscular dystrophy (BMD)
- Conditions
- Becker Muscular Dystrophy, Muscular Dystrophies, Muscular Dystrophy in Children, Muscular Dystrophy, Becker
- Trial name
- GRASP-01-002 (NCT05257473)
- Where
- 11 sites in United States, New Zealand and 1 more
- Volunteers
- 59 people
- Sponsor
- Virginia Commonwealth University
Epidermolysis Bullosa (EB), Chronic Wounds
Topical Insulin Versus Irradiated Amniotic Fluid Gel for Wound Healing in Epidermolysis Bullosa
This study aims to evaluate and compare the safety and efficacy of topical insulin and topical irradiated amniotic fluid gel in promoting wound healing in patients with epidermolysis bullosa (EB).
- Conditions
- Epidermolysis Bullosa (EB), Chronic Wounds, Wound Healing
- Trial name
- EB-INS-AFG (NCT07907523)
- Testing
- Topical Insulin (Actrapid®), Topical Irradiated Amniotic Fluid Gel, No active study treatment
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Hepatitis C,Chronic Children, Only
Twelve Weeks Sofosbuvir/Daclatasvir in HCV Infected Children Aged 6-18 Years
Recently the era of direct-acting antiviral drugs for hepatitis C treatment has changed the world map of HCV. Results in adults are promising. FDA approved only two drugs in the pediatric age group 12 to 17 years.
- Trial name
- NCT07905989
- Testing
- Sofosbuvir/Daclatasvir
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- National Liver Institute, Egypt
Healthy Eating, Nutrition Literacy
Screen-Based Simulation for Adolescents' Healthy Eating Attitudes and Nutrition Literacy
This randomized controlled trial aimed to evaluate the effect of healthy eating education delivered through screen-based simulation on healthy eating attitudes and nutrition literacy in adolescents attending a high school.
- Conditions
- Healthy Eating, Nutrition Literacy, Adolescent Nutrition
- Trial name
- NCT07901361
- Testing
- Screen-Based Simulation Healthy Eating Education, Slide Presentation Healthy Eating Education
- Where
- Turkey (Türkiye)
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Balikesir University
Behavioral Insomnia of Childhood
Development of Sleep Intervention for Parent and Child
This study aims to develop and test the intervention program to help manage parental thoughts in parents with child sleep problems.
- Trial name
- NCT05806450
- Testing
- Intervention, Active control condition
- Where
- South Korea
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Sungshin Women's University
Acne Vulgaris
Efficacy and Safety of Adapalene Gel and Hyaluronic Acid Versus Adapalene Gel Alone in Mild to Moderate Acne Vulgaris
Acne vulgaris affects around 85% of adolescents and young adults. Adapalene, a topical retinoid, is a common treatment but often causes irritation, leading to poor adherence.
- Trial name
- NCT07102186
- Testing
- use of adapalene gel 0.1% and hyaluronic acid at bedtime, use of adapalene gel 0.1% once daily at bedtime
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Badr University
Childhood Absence Epilepsy, Juvenile Absence Epilepsy
A Study to Evaluate the Efficacy, Safety, and Tolerability of Brivaracetam as Monotherapy in Patients 2 to 25 Years of Age With Childhood Absence Epilepsy or Juvenile Absence Epilepsy
The purpose of the study is to test the efficacy, safety and tolerability of brivaracetam monotherapy in study participants 2 to 25 years of age inclusive with childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE).
- Trial name
- EXPAND (NCT04666610)
- Testing
- Brivaracetam
- Where
- 35 sites in United States, Georgia and 5 more
- Volunteers
- 154 people
- Sponsor
- UCB Biopharma SRL
Kidney Failure, Chronic, End-Stage Renal Disease
Clazakizumab in Highly-HLA Sensitized Patients Awaiting Renal Transplant
Patients who have had a previous allograft failure represent a major problem for transplant centers as they are highly-human leukocyte antigen (HLA) sensitized and unlikely to receive another transplant without significant…
- Conditions
- Kidney Failure, Chronic, End-Stage Renal Disease, Transplant Glomerulopathy, Transplant;Failure,Kidney
- Trial name
- NCT03380962
- Testing
- Clazakizumab
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stanley Jordan, MD
Asthma in Children
Evaluation of the Asthma Management Program to Promote Activity for Students in Schools (Asthma-PASS)
Physical activity (PA) is an important component of asthma management in children. Studies show that PA is associated with decreased severity of asthma symptoms, as well as improved disease control and quality of life.
- Trial name
- NCT04576442
- Testing
- Asthma-PASS, Basic Asthma Management (AM), Child/Caregiver Education session
- Where
- United States
- Volunteers
- 452 people
- Sponsor
- Montefiore Medical Center
Mind Mapping, Nursing Students
Mind Mapping: Impact on Critical Thinking and Problem-Solving Skills
This randomized controlled trial aims to evaluate the effectiveness of the mind mapping method in enhancing critical thinking and problem-solving skills among nursing students.
- Conditions
- Mind Mapping, Nursing Students, Critical Thinking
- Trial name
- Mind mapping (NCT07548658)
- Testing
- Mind mapping
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Gazi University
Orthodontic Aligners
The Efficiency of Clear Aligners in Maxillary Molar Distalization: A Randomized Clinical Trial.
The aim of this study is to evaluate the accuracy of clear aligners on the amount of the maxillary molar distalization.
- Trial name
- Aligner (NCT06330571)
- Testing
- Molar distalization by aligners with attachment
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Muscular Dystrophies, Muscle Myopathies
Genetic and Physical Study of Childhood Nerve and Muscle Disorders
Background: Some nerve and muscle disorders that start early in life (before age 25), like some forms of muscular dystrophy, can run in families. However, the genetic causes of these disorders are not known.
- Conditions
- Muscular Dystrophies, Muscle Myopathies, Hereditary Spastic Paraplegias, Inherited Neuropathies
- Trial name
- NCT01568658
- Where
- United States
- Volunteers
- 2,586 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Muscular Atrophy, Spinal
A Study to Learn About the Effect of Nusinersen (BIIB058) Given as Injections to Children With Spinal Muscular Atrophy (SMA) Who Were Previously Treated With Onasemnogene Abeparvovec (RESPOND)
In this study, researchers will learn more about the use of nusinersen (BIIB058) in participants with spinal muscular atrophy (SMA).
- Trial name
- RESPOND (NCT04488133)
- Testing
- Nusinersen
- Where
- 15 sites in United States, Germany and 3 more
- Volunteers
- 46 people
- Sponsor
- Biogen
Cerebral Palsy (CP)
Association Between Extremity Muscle Strength and Functional Outcomes in Children With Cerebral Palsy
The aim of this study was to evaluate whether upper and lower extremity muscle strength is a factor in activity, participation and quality of life parameters in school-age children with CP and to reveal the difference in upper…
- Trial name
- NCT07448207
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
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