Clinical trials: 18F- Fluorocholine
Carcinoma, Hepatocellular
Multimetabolic 18F-Fluorodeoxyglucose (FDG) and 18F-Fluorocholine (FCH) Positron Emission Tomography (PET) as an Early Predictive Factor of Overall Survival in Patients With Advanced Hepatocellular Carcinoma Treated With Sorafenib
Hepatocellular carcinoma (HCC) is the third cause of death by cancer. For patients with inoperable advanced HCC, systematic therapy with Sorafenib, a multikinase inhibitor that has both antiangiogenic and antiproliferative…
- Trial name
- PREMETHEP (NCT02847468)
- Testing
- FDG Positron Emission Tomography, FCH Positron Emission Tomography
- Where
- France
- Volunteers
- 61 people
- Sponsor
- Centre Georges Francois Leclerc
Prostate Cancer
Functional Medical Imaging Quantization in Prostate Cancer
Prostate cancer is the most common cancer in men over 50 years old and the third leading cause of cancer death. Because of the variety of prostate cancers, different treatments exist.
- Trial name
- QUIP (NCT03376360)
- Where
- France
- Volunteers
- 61 people
- Sponsor
- University Hospital, Brest
Prostate Cancer
PET/MRI for Men Being Considered for Radiotherapy for Suspected Prostate Cancer Recurrence Post-Prostatectomy
The PROPS trial is for men being considered for radiotherapy due to the suspicion that their prostate cancer has recurred following the surgical removal of their prostate (prostatectomy).
- Trial name
- PROPS (NCT02131649)
- Testing
- 18F-FCH PET/MRI Scan
- Where
- 10 sites in Australia, Canada and 1 more
- Volunteers
- 99 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hyperparathyroidism, Primary
18F-Fluorocholine for the Detection of Parathyroid Adenomas
The investigators are studying the ability of F18 labeled fluorocholine PET to localize parathyroid adenomas in patients with hyperparathyroidism prior to surgery.
- Trial name
- NCT03764007
- Testing
- 18F-Fluorocholine, Positron Emission Tomography (PET)
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Thomas Hope
Prostate Cancer
11C- and 18F-Choline PET/MR Imaging for Prostate Cancer
This phase II trial studies how well 11C-choline (carbon C 11 choline) and 18F-choline (fluorine F 18 choline) positron emission tomography/magnetic resonance (PET/MR) imaging works in diagnosing patients with unfavorable…
- Trial name
- NCT02397408
- Testing
- Carbon C 11 Choline, Fluorine F 18 Choline, Positron Emission Tomography (PET) / Magnetic Resonance Imaging (MRI)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of California, San Francisco
Prostate Cancer
[18F] Fluorocholine FCH Positron Emission Tomography (PET)/Computed Tomography (CT) for Detection of Prostate Cancer Lymph Nodes Metastases
The objective of this trial is to assess the value of 18F-choline PET/CT for the detection of regional lymph node metastases from prostate cancer.
- Trial name
- PROPET (NCT00670527)
- Testing
- [18F] Fluorocholine PET/CT
- Where
- Denmark
- Volunteers
- 205 people
- Sponsor
- Odense University Hospital
Multiple Myeloma
FCH vs FDG PET/CT in Detection of Lesions in Patients With Multiple Myeloma (MIM)
Hybrid positron emission tomography/computed tomography (PET/CT) has now become available to detect tumors in patients with multiple myeloma.
- Trial name
- MIM (NCT04349358)
- Testing
- FDG and FCH PET/CT
- Where
- 3 sites in France
- Volunteers
- 38 people
- Sponsor
- Centre Georges Francois Leclerc
Plaque, Atherosclerotic
Molecular Imaging of Plaque Vulnerability
Accumulating data in the literature suggests that radiolabeled-choline (18F-choline) is a sensitive molecular tracer for PET imaging that is taken up in activated cells and, as such, is able to identify active inflammatory sites.
- Trial name
- PARISK (NCT02640313)
- Testing
- 18F-choline PET-MR imaging
- Where
- Netherlands
- Volunteers
- 14 people
- Sponsor
- Maastricht University Medical Center
Glioma
Multimodal Diagnostic Assessment of Cerebral Gliomas With FET & FCH PET/CT, and Magnetic Resonance Imaging/Spectroscopy
The aim of this study is to establish the diagnostic value of O-(2-[18F]-fluoroethyl)-L-tyrosine (FET) PET-CT, [18F]-fluorocholine (FCH) and magnetic resonance imaging (MRI) combined with magnetic resonance spectroscopy (MRS) in…
- Trial name
- Gliomes-FLP (NCT00939315)
- Where
- Switzerland
- Volunteers
- 51 people
- Sponsor
- University of Lausanne Hospitals
Prostate Cancer
Whole Body Bone Scan vs 18F-Choline PET/CT in Prostate Cancer
Prostate cancer is currently the leading newly diagnosed cancer in the industrialized world. Treatment of prostate cancer is highly dependent on the stage of the disease. Current methods for staging are known to be inaccurate.
- Trial name
- NCT02232685
- Testing
- 18F-Choline PET/CT
- Where
- Denmark
- Volunteers
- 143 people
- Sponsor
- Odense University Hospital
Prostate Cancer
The Safety and Efficacy of 18F-Fluoromethylcholine (18F-FCH) PET/CT in Prostate Cancer
The objectives of this study are to confirm the safety and efficacy of FCH-PET/CT and to establish our ability to reproduce results from the literature using FCH-PET/CT as a diagnostic and decision making tool in the management…
- Trial name
- NCT02840552
- Testing
- 18F-Fluoromethylcholine (18F-FCH)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Prostatic Neoplasm, Positron-Emission Tomography
Trimodal (18)F-choline-PET/mpMRI/TRUS Targeted Prostate Biopsies
Prostate cancer is the first cancer in humans (25%). The most widely used tracer in oncology, the 18-Fluoro DeoxyGlucose does not allow the study of prostatic neoplasia.
- Conditions
- Prostatic Neoplasm, Positron-Emission Tomography, Fluorocholine
- Trial name
- PROSTEPIRM (NCT02971995)
- Testing
- PET Scan ou TEP-TDM, mpMRI
- Volunteers
- 31 people
- Sponsor
- Lille Catholic University
Prostate Cancer
Multi-modality Prostate Cancer Image Guided Interventions
This is a non-randomized, prospective trial of men who are scheduled for radical prostatectomy for treatment of prostate cancer, or repeat biopsy for localized prostate cancer as standard of care and who will undergo a series of…
- Trial name
- IGPC-2 (NCT04009174)
- Testing
- Imaging Panel
- Where
- Canada
- Volunteers
- 52 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hyperparathyroidism
18F-fluorocholine PET/CT for Hyperparathyroidism
Hyperparathyroidism is a common endocrine disorder which can result in many severe complications. For patients with hyperparathyroidism, Tc-99m sestamibi imaging is the major imaging tool for pre-operative localization of the…
- Trial name
- NCT04316845
- Testing
- 18F-fluorocholine PET/CT
- Where
- Taiwan
- Volunteers
- 38 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Prostate Cancer
F-18-Fluorocholine PET/CT and MR Imaging/ Spectroscopy in the Management of Primary and Recurrent Prostate Cancer
The purpose of this study is to demonstrate that realization of guided biopsies by multimodal imaging with 18F-fluorocholine PET / CT and MR Imaging/spectroscopy would allow to increase the rate of detection prostate cancer…
- Trial name
- NCT00963755
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University of Lausanne Hospitals
Prostate Cancer
Choline PET/CT and MRI for Targeted Prostate Biopsy
This research study will access the using of a radiotracer, 18F-choline PET/CT and MRI for prostate cancer in patients undergoing diagnostic prostate biopsy.
- Trial name
- NCT01751737
- Testing
- Prostate Cancer Imaging
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Michigan
Primary Hyperthyroidism
Localization of Parathyroid Adenoma by Fluorocholine PET/MRI (Positron Emission Tomography -MRI)
A comparative prospective study to evaluate different imaging modalities (pet-ct and pet-mr) prior to surgery in parathyroid tumor patients.
- Trial name
- NCT02843542
- Testing
- PET-MR, PET-CT
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Assuta Medical Center
Hepatocellular Carcinoma, Liver Disease
To Evaluate the Efficacy and Safety of (18F-FCH) Comparing With (18F-FDG) for Detecting Hepatocellular Carcinoma
Liver cancer is a major cause of death among patients of east or southeast asian descent, as well as other population groups, notably in central and west Africa.
- Trial name
- NCT02074202
- Testing
- 18F- fluorocholine, 18F- fluorodeoxyglucose
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- National Taiwan University Hospital
Breast Neoplasms, Female
Fluorocholine PET/MR in Breast Cancer
Objectives: Our study is conducted to use the pre-treatment Fluorocholine (FCH) Positron emission tomography/magnetic resonance (PET/MR) imaging in breast cancer patients, to investigate whether the conventional PET/MR imaging…
- Trial name
- NCT07587086
- Testing
- PET-MRI (PET/MR)
- Where
- Taiwan
- Volunteers
- 195 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Hyperparathyroidism, Parathyroid Adenoma
The Utility of 18F-fluorocholine PET/CT in the Imaging of Parathyroid Adenomas
We assessed sensitivity of 18F-FCH PET/CT in preoperative localisation of hyperfunctioning parathyroid tissue in patients with primary hyperparathyroidism (PHPT).
- Trial name
- NCT04570033
- Testing
- We assessed sensitivity of 18F-FCH PET/CT in preoperative localisation of hyperfunctioning parathyroid tissue in patients with primary hyperparathyroidism
- Volunteers
- 65 people
- Sponsor
- Military Institute od Medicine National Research Institute