Clinical trials: 25-Hydroxyvitamin D Concentration
25-hydroxyvitamin D Concentration (Vitamin D Status)
D-Light Intervention
Vitamin D insufficiency has become a global concern, with low vitamin D status associated with bone disorders, cardiovascular disease and certain cancers.
- Trial name
- D-Light (NCT02495584)
- Testing
- Fortified milk (10µg vitamin D3), 10µg vitamin D3 supplement
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Infant, Premature, Diseases
Calcium (ca),Phosphorus( P) and 25-hydroxyvitamin D(25OHD)] in Infants Born ≤ 32 PMA Gestational Weeks (GA)
It has not yet been established the optimal dose of vit. D for preterm infants in Poland. It is not known what dose of vit. D will provide the correct concentration of vit.
- Trial name
- Ca-P (NCT03691896)
- Testing
- Cholecalciferol 400, Cholecalciferol 800, Cholecalciferol 1200
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Centre of Postgraduate Medical Education
Inflammation
Effect of a One Time Dose of Cholecalciferol on Serum Concentration of 25-Hydroxyvitamin D and Macrophages
Optimal Vitamin D dosing to obtain adequate serum concentrations of 25-hydroxyvitamin D (25OHD) is controversial. The optimal dose and dosing interval is unknown, and the tendency over the last few years is to give higher, less…
- Trial name
- NCT02920502
- Testing
- Arm 2: cholecalciferol 50,000 IU, Arm 3: cholecalciferol 100,000 IU, Arm 4: cholecalciferol 200,000 IU
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Serum 25-hydroxyvitamin D Concentrations (25OHD)
Dietary Requirement for Vitamin D in Adolescents Aged 14-18 Years
It is known that low vitamin D status is a very common problem in the UK. It is also known that a lack of vitamin D availability has potentially serious health implications, especially with respect to bone and muscle function.
- Trial name
- NCT02150122
- Testing
- Vitamin D3
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Vitamin D Receptor Target Gene Expression, Serum 25(OH)D Concentration
The Effect of a High-dose Oral Vitamin D3 Bolus on Serum 25(OH)D3 and Vitamin D Receptor Target Gene Expression
The purpose of the study is to investigate whether a high-dose vitamin D3 oral bolus (2000 micrograms) produces marked vitamin D receptor target gene expression response and whether there is large inter-individual variation.
- Trial name
- VitDbol (NCT02063334)
- Testing
- Vitamin D3
- Where
- Finland
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Serum 25-hydroxyvitamin D Concentrations (25OHD)
Marwo-D Research -Need for Vitamin D in Different Population Groups
Insufficient intake of vitamin D is a public health problem, affecting about 40% of the Finnish population in the winter. Vitamin D has a wide range of health effects: in addition to its effect on bone, it is known to affect…
- Trial name
- ODIN (NCT02212223)
- Testing
- Vitamin D3
- Where
- Finland
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Vitamin D Receptor Target Gene Expression, Serum 25(OH)D Concentration
Efficiency of Vitamin D3 and 25-hydroxyvitamin D3 on Transcriptomic Changes of Low Vitamin D Responders
The purpose of the study is to investigate in vivo whether a high-dose vitamin D3 oral bolus (2000 micrograms) produces marked vitamin D receptor target gene expression response and whether there is large inter-individual…
- Trial name
- VitDHiD (NCT03537027)
- Testing
- Vitamin D3
- Where
- Finland
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Eastern Finland
Vitamin D Deficiency, Musculoskeletal Diseases
Vitamin D in School Children
The primary purpose of this study it to investigate total circulating 25-hydroxyvitamin D (25(OH)D) in school children (aged 4-11years) in Northern Ireland; thereby establishing the prevalence of vitamin D status (deficiency…
- Conditions
- Vitamin D Deficiency, Musculoskeletal Diseases, Cognitive Delay, Mild
- Trial name
- DVinCHI (NCT05018988)
- Testing
- Oral vitamin D spray
- Where
- United Kingdom
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- University of Ulster
Serum 25-hydroxyvitamin D Concentrations (25OHD)
The BreaD Study - Bio-availability of D2 Vitamin Present in Bread
Vitamin D3 is synthesized in skin exposed to ultraviolet-B-irradiation of sunlight. However, in Northern Europe, including Finland, exposure to sunlight is limited or non-existent in winter.
- Trial name
- BreaD_ODIN (NCT02525003)
- Testing
- Vitamin D2, Vitamin D3, Vitamin D2 fortified bread
- Where
- Finland
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
25-hydroxyvitamin D Serum Concentrations
Trial of Vitamin D Fortified Milk
Prevalence of VDD is high worldwide, even in sunbathed equatorial regions where it had not been suspected before. The most cost-effective method for reducing population-wide VDD is through fortification of commonly consumed…
- Trial name
- NCT01909622
- Testing
- Vitamin D, No vitamin D
- Where
- 2 sites in Colombia
- Volunteers
- 80 people
- Sponsor
- University of Michigan
Low 25-hydroxyvitamin D Concentrations
A Pilot Study to Examine the Effects of Vitamin D Supplementation on Mitochondrial Bioenergetics in Older Adults
This pilot study is a 4-month open label trial in 15 older (65-89 yrs) men and women with initial 25(OH)D concentrations of 12-<18 ng/mL to explore the effect of increasing 25(OH)D concentrations to ≥30 ng/mL through vitamin D3…
- Trial name
- NCT02445066
- Testing
- Vitamin D3
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Wake Forest University Health Sciences
Vitamin D Deficiency, 25-Hydroxyvitamin D Concentration
Is Vitamin D2 Treatment-associated Decrease in 25(OH)D3 Level a Reciprocal Phenomena?
Several studies have demonstrated that D2 treatment is associated with a decrease in 25(OH)D3 level and therefore have proposed that D3 would be preferable in term of raising total 25(OH)D level.
- Trial name
- NCT03035084
- Testing
- Vitamin D3, Vitamin D2
- Where
- Saudi Arabia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Faisal Specialist Hospital & Research Center
Vitamin D Deficiency, Cardiometabolic Risk Factors
Comparison of Sunlight Exposure and Vitamin D Supplementation on Serum 25-hydroxyvitamin D Levels
This study aimed to compare the effects between sunlight exposure and oral vitamin D supplementation on serum 25-hydroxyvitamin D concentration and metabolic markers in Korean young adults.
- Trial name
- NCT03310242
- Testing
- Sunlight Exposure, Vitamin D Supplementation
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital