Clinical trials: 28 Day Mortality
Covid19, Critically Ill
Risk Factors for Mortality for COVID-19 Admitted to an Intensive Care Unit
Studying clinical characterization of critically ill COVID-19 patients in a single center Studying Risk factors for Day 28 Mortality in COVID-19 patients admitted to intensive care unit
- Trial name
- ICUCOVID-KK (NCT04805645)
- Testing
- No intervention (Retrospective Cohort Observational)
- Where
- Malaysia
- Volunteers
- 50 people
- Sponsor
- Clinical Research Centre, Malaysia
Septic Shock
A Prediction Model of 28-day Mortality in Septic Shock
This clinical study adopts the design of cohort research, selects the sepsis shock patients admitted to our hospital ICU as the research object, takes the 28-day mortality rate as the outcome index, collects the baseline data of…
- Trial name
- NCT04915625
- Where
- China
- Volunteers
- 530 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Sepsis, Septic Shock
Comparing Blood-Based Ratios for Predicting Outcomes in Sepsis and Septic Shock
Sepsis and septic shock are serious conditions associated with a high risk of organ dysfunction and death. Simple laboratory-based markers may help identify critically ill patients who are at greater risk of poor outcomes.
- Trial name
- NCT07819708
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Benha University
All Conditions Requiring Non-cardiac Surgery
Impact of Training on the Use of Software and Digital Monitoring Tools During General Anesthesia for Intermediate/Major-risk Surgery on Morbidity and Mortality at 28 Days
Tools such as surgical plethysmographic index, state entropy, train-of-four monitors exist to optimize the conduct of general anesthesia in intermediate and major risk surgery as defined by the 2022 European Society of Cardiology…
- Trial name
- AoA QUALITY (NCT06111248)
- Testing
- Training
- Where
- France
- Volunteers
- 1,028 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Sars-CoV2
LILLE COVID RESEARCH NETWORK (Covid-19)
The Lille University Hospital developped a research objective common to all the services which took care of patients, "suspected patient", "possible case", "probable case" or "confirmed case" infected with SARS-CoV-2 by…
- Trial name
- LICORNE (NCT04475211)
- Where
- France
- Volunteers
- 757 people
- Sponsor
- University Hospital, Lille
Subarachnoid Hemorrhage, Aneurysmal
Predictive Role of f-QRST Angle in Subarachnoid Hemorrhage
The investigators investigated the association between the frontal QRS/T angle measured on admission ECG and 28-day mortality, as well as neurological outcome in patients with non-traumatic aneurysmal SAH.
- Trial name
- f-QRST in SAH (NCT07196891)
- Testing
- frontal-QRST angle, Hunt-Hess scale, modified Fisher scale
- Where
- Turkey (Türkiye)
- Volunteers
- 354 people
- Sponsor
- Haseki Training and Research Hospital
28 Day Mortality
Thromboelastography Guides a Multicentre Cluster Controlled Study of Plasma Exchange for Hepatitis B Associated Acute-on-chronic Liver Failure
In the past ten years, the extracorporeal liver support system has been widely used in clinical practice as a first-line treatment of liver failure.
- Trial name
- NCT04747106
- Testing
- plasma exchange
- Where
- China
- Volunteers
- 390 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Mechanically Ventilated Patients
Mechanical Ventilation Practices in Uganda's Intensive Care Units
A prospective cohort study carried out in four ICUs in Uganda. All patients, 18 years and above initiated on mechanical ventilation will be recruited.
- Trial name
- NCT03800849
- Where
- Uganda
- Volunteers
- 214 people
- Sponsor
- Makerere University
28-day Mortality
Albumin Infusion Targets on Mortality in Patients With Abdominal Sepsis
Hypoalbuminemia has been shown to be significantly associated with increased mortality from abdominal sepsis, and early albumin infusion to maintain high serum albumin concentrations may be beneficial for the recovery of patients…
- Trial name
- NCT06874634
- Testing
- Human serum albumin injection
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Nanfang Hospital, Southern Medical University
28 Day Mortality
Co-inhibitory Molecules on Treg and miR-155-5p in Patients With Sepsis
there is high mortality rate of sepsis, 36% in 90-days of sepsis in China, and there is no effective treatment. Immunosuppression mediated by sepsis is an important cause of death in patients.
- Trial name
- NCT05126537
- Testing
- no intervention
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Southeast University, China
Mechanical Ventilation Complication, Ventilator Induced Lung Injury
Mechanical Power and Mortality in Mechanically Ventilated Adults
This prospective observational cohort study aims to investigate the relationship between mechanical power during the first 72 hours of invasive mechanical ventilation and 28-day mortality in mechanically ventilated adult patients…
- Conditions
- Mechanical Ventilation Complication, Ventilator Induced Lung Injury, ARDS, ICU Mortality (Survival Rate)
- Trial name
- NCT07836153
- Where
- Egypt
- Volunteers
- 116 people
- Sponsor
- Zagazig University
Sarcopenia, Cancer
CT-Determined Sarcopenia and Mortality in Critically Ill Cancer Patients
The goal of this observational study is to evaluate the association between computed tomography-determined sarcopenia and muscle quality impairment with 28-day mortality in adult patients (aged 18 and older) with solid or…
- Conditions
- Sarcopenia, Cancer, Critical Illness, Malnutrition
- Trial name
- NCT07761481
- Testing
- Computed Tomography Muscle Assessment (HUAC)
- Where
- Mexico
- Volunteers
- 23 people
- Sponsor
- Hospital H+ Queretaro
Acute Pancreatitis, Pancreatitis
CBC-Derived Inflammatory Indices in Acute Pancreatitis
This prospective observational study aims to evaluate the prognostic value of complete blood count (CBC)-derived inflammatory indices, including neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and…
- Trial name
- NCT07793734
- Volunteers
- 109 people
- Sponsor
- Assiut University
Fluid and Electrolyte Imbalance, Anesthesia
BIA-Guided vs. Conventional Fluid Resuscitation in ICU Patients
In this study aimed to compare bioelectrical impedance analysis (BIA)-guided fluid resuscitation with conventional fluid management strategies in patients admitted to the intensive care unit (ICU) following major surgery.
- Trial name
- BIA-FLUID (NCT07142083)
- Testing
- Bioelectrical Impedance Analysis (BCM), Conventional Fluid Management
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ondokuz Mayıs University
Mortality, Clinical Deterioration
EWSs and 28-Day Mortality in Geriatric ED Patients
This prospective observational cohort study evaluated the prognostic performance of commonly used early warning scores for predicting 28-day all-cause mortality among geriatric patients presenting to the emergency department with…
- Conditions
- Mortality, Clinical Deterioration, Geriatric Patients, Frailty
- Trial name
- EWSsGer (NCT07577349)
- Testing
- Demographic Characteristics, Comorbidities, Vital Signs
- Where
- Turkey (Türkiye)
- Volunteers
- 2,744 people
- Sponsor
- Haseki Training and Research Hospital
Subarachnoid Hemorrhage, Aneurysmal
Predicting 28-Day Mortality in Subarachnoid Hemorrhage
The investigators investigated the predictive ability of clinical and radiological scores, including the Glasgow coma scale (GCS), Hunt-Hess, World Federation of Neurological Surgeons (WFNS), and modified Fisher scales, as well…
- Trial name
- SAHstdy (NCT06563219)
- Testing
- Glasgow coma scale, Hunt-Hess scale, World Federation of Neurological Surgeons (WFNS) scale
- Where
- Turkey (Türkiye)
- Volunteers
- 451 people
- Sponsor
- Haseki Training and Research Hospital
Covid-19, Thromboembolic Events
Anticoagulant Therapy and 28-days Mortality in Critically Ill COVID-19 Patients
The aims of the study are to to associate anticoagulation (AC) regime with outcome in critically ill patients with Covid-19. This will be done by describe baseline characteristics and comorbidities before hospital admission…
- Conditions
- Covid-19, Thromboembolic Events, Bleeding
- Trial name
- NCT04412304
- Testing
- Dose of Tinzaparin or Dalteparin
- Where
- Sweden
- Volunteers
- 166 people
- Sponsor
- Karolinska Institutet
Sepsis
Safety and Efficacy of Recombinant Human Platelet-Activating Factor Acetylhydrolase for the Treatment of Severe Sepsis
The objective of this study is to demonstrate that rPAF-AH is safe and reduces 28 day all cause mortality in patients with severe sepsis.
- Trial name
- NCT00037687
- Testing
- rPAF-AH
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- ICOS Corporation
Sepsis
Differential Clinical Phenotypes Of Early CD4+ And CD8+ T-Cell Recovery And Association With 28-Day Mortality In Sepsis Patients
This is a retrospective non-interventional cohort study. Medical records of adult patients with sepsis admitted to the intensive care unit will be retrospectively reviewed.
- Trial name
- NCT07787780
- Testing
- CD4+/CD8+ T-cell dynamic recovery status
- Where
- China
- Volunteers
- 303 people
- Sponsor
- Sichuan Provincial People's Hospital
Septic Shock, Nonchemotherapy Drug-induced Neutropenia
Russian Clinical Trial of Mesenchymal Cells in Patients With Septic Shock and Severe Neutropenia
Septic shock remains a significant clinical problem associated with high rates of mortality among neutropenic patient despite antimicrobial therapy and supportive care.
- Conditions
- Septic Shock, Nonchemotherapy Drug-induced Neutropenia, Neutropenia After Chemotherapy in Oncohematological Patients, Neutropenia in Patients With Aplastic Anemia
- Trial name
- NCT01849237
- Testing
- Mesenchymal stromal cells, Standard therapy of septic shock
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- National Research Center for Hematology, Russia