Clinical trials: 65 Years Older
Tetanus
Antitetanus Vaccination for People Older Than 65 Years.
In the last ten years, more than one hundred generalized tetanus cases were declared in France. Most of them were affecting people older than 70 years with an important mortality (around 28%).
- Trial name
- VAT65 (NCT03266211)
- Testing
- Questionnaire Patients, Questionnaire General practitioner
- Where
- France
- Volunteers
- 261 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Influenza
Safety, Tolerability, and Immunogenicity of Different Combinations of Trivalent Influenza Vaccine Varying Influenza Antigen Dose, Adjuvant Dose, and Route of Administration in Healthy Elderly Individuals Ages 65 Years and Older
The study will evaluate the safety, tolerability and immunogenicity of different doses and types of Influenza Vaccine in healthy elderly subjects.
- Trial name
- NCT00848848
- Testing
- Trivalent Influenza Vaccine, Trivalent Influenza Vaccine + high A, Trivalent Influenza Vaccine + ¼ dose adjuvant
- Where
- Belgium
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Seqirus
Invasive Extraintestinal Pathogenic Escherichia Coli Disease (IED) Prevention
A Study of 9-valent Extraintestinal Pathogenic Escherichia Coli Vaccine (ExPEC9V) and High-dose Quadrivalent Influenza Vaccine, With and Without Co-administration, in Adults Aged 65 Years or Older
The purpose of this study is to show that high-dose quadrivalent seasonal influenza vaccine (HD QIV) given together with 9-valent extraintestinal pathogenic Escherichia coli vaccine (ExPEC9V) does not induce lower antibody…
- Trial name
- Engage (NCT06134804)
- Testing
- ExPEC9V, HD quadrivalent influenza vaccine
- Where
- 41 sites in United States, Belgium and 2 more
- Volunteers
- 959 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Flu Vaccine
Senescent Immunity in Elders and Vaccine Responses (SILVER)
To study the effects of age on the immune system's response to flu vaccine and to study the connection between the immune system and physical and cognitive changes associated with aging.
- Trial name
- NCT04077424
- Testing
- Fluzone-High Dose Quadrivalent, Fluad, Flublock
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Prophylaxis of A/H3N2v Influenza
Safety and Immunogenicity of Three Dosage Levels of Swine Influenza Vaccine in Children Ages 3 to <9 Years, Adolescents 9 to <18 Years, Adults 18 to <65 Years and Elderly 65 Years and Older.
Evaluate the safety and immunogenicity of three dosage levels of swine influenza vaccine in children ages 3 to <9 years, adolescents 9 to <18 years, adults 18 to <65 years and elderly 65 years and older.
- Trial name
- NCT01855945
- Testing
- Swine Influenza
- Where
- 11 sites in United States
- Volunteers
- 627 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Influenza
Clinical Study of the Immunogenicity of GSK Biologicals' Influenza Vaccine GSK2186877A in People Aged 65 Years or Older
This clinical trial aims to study the immunogenicity of GSK Biologicals' influenza vaccine GSK2186877A in people aged 65 years or older.
- Trial name
- NCT00765076
- Testing
- GSK Biologicals' influenza vaccine GSK2186877A, GSK Biologicals' Fluarix
- Where
- 4 sites in United States, Spain
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy
A Study to Evaluate a Range of Dose Levels and Vaccination Intervals of Ad26.COV2.S in Healthy Adults and Adolescents
The primary purpose of this study is to assess humoral immune responses of 3 dose levels of Ad26.COV2.S administered intramuscularly (IM) as a 2-dose schedule (56 days apart); Ad26.COV2.S administered IM as a single vaccination…
- Trial name
- NCT04535453
- Testing
- Ad26.COV2.S
- Where
- 13 sites in Germany, Netherlands and 2 more
- Volunteers
- 635 people, healthy volunteers welcome
- Sponsor
- Janssen Vaccines & Prevention B.V.
Individuals Over 65 Years of Age
Breath Meditation on the Older People
A decrease in physical activity during old age leads to a decline in quality of life and life satisfaction. Increased stress and anxiety levels during this period negatively affect individuals' mood and reduce their quality of…
- Trial name
- MEDITATION (NCT07263828)
- Testing
- breathing meditation
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Older Adults, Older Adults (65 Years and Older)
SOC-based Behavioral Intervention to Promote Walking
Drawing on the Selection, Optimization, and Compensation (SOC) model of adaptive development, this study tested whether a structured behavioral intervention could enhance walking activity and well-being through improvements in…
- Trial name
- SOCWalk (NCT07312331)
- Testing
- SOC-based walking intervention, general health education program
- Where
- China
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Ling Yang
Sleep Quality, Older Adults (65 Years and Older)
Effect of Health Promotion Model-Based Oculomotor Exercise Program on Sleep Quality in Older Adults
The goal of this clinical trial is to investigate the effect of a Health Promotion Model-based oculomotor exercise program on sleep quality among older adults living in a nursing home.
- Trial name
- NCT07261124
- Testing
- Oculomotor Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Walking, Older Adults (65 Years and Older)
Promoting Walking Among Older Adults Through Affective Communication and Step-Monitoring
Physical inactivity increases substantially after age 60 and represents a major public health challenge in older adults, as it is linked to increased risk of functional and cognitive decline and aging problems.
- Conditions
- Walking, Older Adults (65 Years and Older), Messaging, Mobile Applications
- Trial name
- NOSTEP (NCT07570303)
- Testing
- Self-continuity prompts, Step-monitoring reminders, Water intake messages
- Where
- Italy
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Catholic University, Italy
Influenza
Safety, Tolerability and Immunogenicity of Fluzone® With and Without JVRS-100 in Elderly Subjects
This study is designed to determine the optimal dose of JVRS-100 and assess safety, tolerability and immunogenicity of Fluzone® vaccine administered with JVRS-100 adjuvant at one of three dose levels compared to Fluzone® vaccine…
- Trial name
- NCT00936468
- Testing
- Fluzone® vaccine with JVRS-100 adjuvant or Fluzone alone
- Volunteers
- 472 people, healthy volunteers welcome
- Sponsor
- Colby Pharmaceutical Company
Influenza
Immunogenicity and Safety Study of Different Formulations of GlaxoSmithKline (GSK) Biologicals H7N1 Influenza Vaccine Administered to Adults 65 Years of Age and Older
The purpose of this placebo controlled study is to evaluate the safety and immunogenicity of different formulations of GSK Biologicals H7N1 influenza vaccine in subjects 65 years of age and older.
- Trial name
- NCT01949090
- Testing
- Investigational H7N1 vaccine GSK2789869A
- Where
- 8 sites in United States, Canada
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Influenza Vaccination, Older Adults (65 Years and Older)
Influenza Vaccine Immunogenicity in Repeatedly Vaccinated Older Adults
The goal of this clinical trial is to compare immune responses to different influenza vaccine formulations in older adults and to understand how immune aging and repeated annual influenza vaccination affect these responses.
- Conditions
- Influenza Vaccination, Older Adults (65 Years and Older), Immunosenescence, Immunogenicity
- Trial name
- NCT07838298
- Testing
- Standard dose influenza vaccine, MF59 adjuvanted influenza vaccine, High dose influenza vaccine
- Where
- South Korea
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
Appetite, Food Intake
Effect of Sumac on Appetite and Food Intake
Sumac, is a spice that is widely used in Turkish, Iranian and Middle Eastern foods. In these regions, the fruit of sumac is used for seasoning or flavouring, as an appetizer and for souring food.
- Trial name
- NCT05534152
- Testing
- sumac
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Oxford Brookes University
Influenza A, Influenza B, Influenza Vaccination
Phase 2/3 Clinical Trial to Evaluate the Immunogenicity and Safety of GC3114B in Adults Aged 65 Years or Older
This is a multicenter, randomized, double-blind, active-controlled, parallel-group clinical trial in adults aged 65 years or older.
- Trial name
- GC3114B (NCT07883928)
- Testing
- vaccination of GC3114B, Vaccination of Efluelda
- Where
- South Korea
- Volunteers
- 1,806 people, healthy volunteers welcome
- Sponsor
- GC Biopharma Corp
Health Promotion, Older Adults (65 Years and Older)
SCT-Based Health Promotion in Older Adults
This study will be conducted to compare the effects of Peer- and Nurse-Led Health Protection and Promotion Training Programs Based on Social Cognitive Theory (SCT) on the health behaviors of older adults.
- Trial name
- NCT06419465
- Testing
- Peer-Led Health Protection and Promotion Training Program, Health Protection and Promotion Training Program under the Leadership of a Public Health Nurse
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Influenza, Influenza Vaccine
Clinical Trial of Quadrivalent Subunit Influenza Vaccine (Adjuvant) in Chinese Population Aged 65 Years and Older
The objective of this study was to evaluate the safety of quadrivalent subunit influenza vaccine (adjuvant) in people aged 65 years and older.
- Trial name
- NCT07421037
- Testing
- Quadrivalent Subunit Influenza Vaccine (Adjuvant), MF59, 0.9% sodium chloride injection (normal saline)
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ab&B Bio-tech Co., Ltd.JS
Influenza
Safety of Synbiotics as Adjuvant to Influenza Vaccine in Elderly
Probiotics are viable commensal microorganisms that promote the establishment of beneficial microflora. Animal and human studies demonstrate that probiotics can enhance body's immune response to stimuli.
- Trial name
- NCT01304771
- Testing
- Synbiotic AKSB
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Older Adults (65 Years and Older), Older Adults Without Any Specific Clinical Condition
The Effect of Virtual Reality in Older Adults
This research will be conducted to examine the effects of virtual reality on sleep quality and comfort in older adults. This research will be conducted as a single-blind, randomized controlled experimental study with a…
- Trial name
- NCT07499245
- Testing
- using virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kafkas University