Clinical trials: A Single-blind Randomized Controlled Trial
Cicatrix, Scar Prevention
A Study of Single Ascending Dose of LEM-S401 in Healthy Participants
The primary objective of the study is to assess the safety and tolerability of single dose of LEM-S401 in healthy adult subjects.
- Trial name
- NCT04707131
- Testing
- LEM-S401
- Where
- South Korea
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Lemonex Inc.
Parkinson's Disease
A Clinical Trial of LY3962681 in Healthy Volunteers and in Patients With Parkinson's Disease
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics/pharmacodynamics (PK/PD) of LY3962681 in healthy volunteers and patients with Parkinson's disease.
- Trial name
- PROSPECT-PD (NCT06565195)
- Testing
- LY3962681
- Where
- 16 sites in United States, Germany and 3 more
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Prevail Therapeutics
Healthy Subjects
Evaluation of Safety, Tolerability & Pharmacokinetics of JYP0061 in Healthy Adults.
The goal of this clinical trial is to evaluate the safety, tolerability and pharmacokinetic characteristics of JYP0061 in healthy adult subjects.
- Trial name
- NCT06137911
- Testing
- JYP0061
- Where
- China
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Guangzhou JOYO Pharma Co., Ltd
Immunogenicity, Safety
mRNA Booster Vaccine(SW-BIC-213) Compared With Pfizer andSinopharm Against Emerging VOCs
Primary#Objectives #Immunogenicity:To demonstrate the non-inferiority of binding antibody response in terms of geometric mean titers (GMT) of mRNA vaccine compare with mRNA COVID-19 vaccine(Pfizer) 14 days post dose.
- Conditions
- Immunogenicity, Safety, Efficacy
- Trial name
- NCT05686161
- Testing
- SW-BIC-213;SARS-Cov-2., Sinopharm (BIBP);SARS-Cov-2., Pfizer(BNT162b2);SARS-Cov-2.
- Where
- Laos
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Stemirna Therapeutics
Osteoporosis, Cardiovascular Disease
Epimedium Prenylflavonoid (EP) Extract for Osteoporosis and Cardiovascular Disease
The primary objective of the trial is to develop Epimedium Prenylflavonoid (EP) extract as a pharmaceutical-quality intervention for post-menopausal osteoporosis and cardiovascular disease.
- Trial name
- NCT02931305
- Testing
- Epimedium Prenylflavonoids Extract
- Where
- Singapore
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Glabellar Frown Lines
A Comparative Study of Botulinum Neurotoxin Type A in Treatment of Moderate to Severe Glabellar Frown Lines
Efficacy and safety of the investigational product, ATGC-110, was evaluated in comparison with Botox for a total of 12 weeks after the administration in treatment of glabellar frown lines.
- Trial name
- NCT04281095
- Testing
- Botulinum toxin type A
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ATGC Co., Ltd.
Healthy Volunteers
Immunogenicity and Safety of Diphtheria, Tetanus, Pertussis (DTaP) Vaccine in 3-month-old Infants
The purpose of this study is to evaluate the safety and immunogenicity of the DTaP in 3-month-old infants.
- Trial name
- NCT06344065
- Testing
- Diphtheria, tetanus and acellular pertussis (component) combined vaccine (adsorbed), Diphtheria, tetanus and acellular pertussis combined vaccine (adsorbed), Diphtheria, tetanus, pertussis (acellular, component), poliomyelitis (inactivated) vaccine (adsorbed) and Haemophilus influenzae type b conjugate vaccine
- Where
- China
- Volunteers
- 1,584 people, healthy volunteers welcome
- Sponsor
- Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd
Autoimmune Diseases
Phase 1 Clinical Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of DWP212525 in Healthy Volunteers
The safety and tolerability of single and multiple administration of DWP212525
- Trial name
- NCT06736587
- Testing
- DWP212525 XXmg
- Where
- South Korea
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Daewoong Pharmaceutical Co. LTD.
HIV Infections
PEPI-TiDP23-C104 is a First in Human Study With a Single Dose Escalation Part and a Multiple Dosing Part for Compounds TMC589337 and TMC589354.
The purpose of the study is to determine the safety, tolerability, and plasma pharmacokinetics (i.e., the levels of TMC589337 and TMC589354 circulating in your blood over time) of increasing single oral doses of TMC589337 and…
- Trial name
- NCT00908414
- Testing
- TMC589337 40 mg, TMC589337 100 mg, TMC589337 200 mg
- Where
- Netherlands
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tibotec Pharmaceuticals, Ireland
Drug Safety, Respiratory Syncytial Virus Infections
A Trial to Assess the Safety, Tolerability, and Pharmacokinetics of MDT-637 in Healthy Volunteers
The purpose of this study is to determine the range of single inhaled doses of a new dry powder product, MDT-637, that are safe and well-tolerated.
- Trial name
- NCT01355016
- Testing
- MDT-637
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- MicroDose Therapeutx, Inc
Screen Time, Performance Enhancing
The Effect of Aerobic Exercise Training on Collegiate eSport Team Players
E-sports, which is called video games that are played in a competitive and organized way in a virtual environment, individually or in like teams, continues to increase its popularity by reaching individuals of all ages with the…
- Conditions
- Screen Time, Performance Enhancing, Injury Prevention, Executive Function
- Trial name
- NCT05317104
- Testing
- Aerobic exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
PechaKucha Method
The Effect of Stoma Care Training Using the PechaKucha Method on Stoma Care Skills and Anxiety in Nursing Studen
Aim: This study aimed to evaluate the effects of stoma care training delivered using PechaKucha (PK) on the stoma care skills and anxiety of nursing students.
- Trial name
- NCT06478966
- Testing
- Experimental
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Obesity
To Evaluate the Safety, Tolerability, PK, PK-PD Relation of KD101 in the Fed State in Obese or Overweight Subjects
To Evaluate the safety, tolerability and pharmacokinetic property after KD101 multiple oral dosing in the fed state in obese or overweight subjects.
- Trial name
- NCT02462031
- Testing
- KD101
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Kwang Dong Pharmaceutical co., ltd.
Systemic Juvenile Idiopathic Arthritis, Periodic Fever Syndrome
Safety, Tolerability and Pharmacokinetic of Recombinant Anti-IL-1β Humanized Monoclonal Antibody Injection
This study is Safety, Tolerability and Pharmacokinetic of Recombinant anti-IL-1β Humanized Monoclonal Antibody injection in Healthy Subjects.
- Trial name
- NCT05027373
- Testing
- SSGJ-613
- Where
- China
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.
Healthy Subjects, Cold Urticaria
A Phase 1 Study of GTX-B001 in Healthy Subjects and Patients With Chronic Inducible Urticaria
This is a first-in-human study aimed at determining the safety of a single dose of GTX-B001 in healthy participants and in people with chronic inducible urticaria.
- Conditions
- Healthy Subjects, Cold Urticaria, Symptomatic Dermographism, Chronic Inducible Urticaria
- Trial name
- CHILL-MC (NCT07181369)
- Testing
- GTX-B001, Normal Saline
- Where
- 5 sites in Germany
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Granular Therapeutics Limited
Cesarean Section Complications, Pain
Obstetric Liposomal Bupivacaine Via Surgical Transversus Abdominis Plane Block for Post Cesarean Pain Control
This study seeks to identify whether the addition of liposomal bupivacaine to regular bupivacaine and saline administered via surgical transversus abdominis plane (TAP) block will reduce the cumulative opioid dose in the first 48…
- Conditions
- Cesarean Section Complications, Pain, Opioid Use
- Trial name
- OBLiBupi (NCT04897841)
- Testing
- Liposomal bupivacaine, Bupivacaine Hydrochloride, saline
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Nonalcoholic Steatohepatitis
A Trial to Evaluate the Safety Tolerability and Pharmacokinetics of B1344 by Subcutaneous Injection in Healthy Subjects
To evaluate the safety, tolerability, and immunogenicity of B1344 by single subcutaneous (s.c.) injection in healthy subjects
- Trial name
- NCT05655221
- Testing
- B1344
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Tasly Biopharmaceuticals Co., Ltd.
Pain
A Trial to Evaluate the Safety and PK Profile of HRS4800 in Healthy Subjects
The study will be conducted to evaluate the safety and PK profile of HRS4800 tablets after single oral administration in different dose levels compared to placebo.
- Trial name
- NCT04862884
- Testing
- HRS4800 tablets
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Healthy
A Phase I Clinical Study Trial of Felbinac Trometamol Injection in China
1. To evaluate the tolerances of healthy subjects treated with Felbinac Trometamol Injection on multiple dose and single dose 2.
- Trial name
- NCT03235778
- Testing
- Felbinac Trometamol Injection
- Where
- China
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Yiling Pharmaceutical Inc.
Myofascial Pain Syndrome, Pain
Treatment of Myofascial Pain Syndrome With Lidocaine Injection and Physical Therapy.
Background: Myofascial pain syndrome (MPS) of the shoulder girdle and cervical region is a common musculoskeletal problem that is often chronic or recurrent.
- Conditions
- Myofascial Pain Syndrome, Pain, Myofascial Trigger Point Pain, Musculoskeletal Pain
- Trial name
- NCT01250184
- Testing
- Physical therapy, Lidocaine injection, Lidocaine injection + physical therapy
- Where
- 2 sites in Colombia
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Grupo Rehabilitacion en Salud