Clinical trials: A-PRF
Partial Edentulism, Dental Implant Placement
Effect of Advanced PRF and Hyaluronic Acid on Dental Implant Healing
This randomized parallel-group clinical trial aimed to evaluate the clinical efficacy of advanced platelet-rich fibrin (A-PRF) combined with hyaluronic acid (HA) in enhancing peri-implant bone formation in patients undergoing…
- Trial name
- NCT07792720
- Testing
- Delayed Dental Implant Placement, Advanced Platelet-Rich Fibrin (A-PRF), Hyaluronic Acid 1.5%
- Where
- Yemen
- Volunteers
- 30 people
- Sponsor
- Samar Ali Abdu Salamah
TMJ Disc Displacement With Reduction
Hyaluronic Acid and I-PRF Mixture for TMJ Disc Displacement Management
The aim of this study is to evaluate the efficacy of hyaluronic acid and I-PRF mixture for intra-articular injection following arthrocentesis in the management of TMJ reducible disc displacement.
- Trial name
- NCT07683650
- Testing
- 18 joints that receive arthrocentesis using 100 ml of ringer lactate solution, Arthrocentesis followed by hyaluronic acid injection, Arthrocentesis followed by injection of hyaluronic acid and betamethasone mixture
- Where
- Egypt
- Volunteers
- 72 people
- Sponsor
- Mansoura University
Palatal Donor Site Wound Healing, Platelet Rich Fibrin
Characterizing the Effects of Platelet-Rich Fibrin (PRF) as a Palatal Wound Dressing on Quality of Life and Sleep Following Mucogingival Surgery. Study Was Conducted at the Air Force Post Graduate Dental School. All HIPPA Consents and Research Informed Consents Are Located at JBSA-Lackland.
The goal of this clinical trial (2-arm) is to determine if the application of platelet rich fibrin (PRF) to palatal donor sites influence patients quality of life, sleep efficiency, and healing following mucogingival surgery.
- Conditions
- Palatal Donor Site Wound Healing, Platelet Rich Fibrin, Sleep Quality, Pain
- Trial name
- NCT07637838
- Testing
- Platelet rich fibrin, Control Group: collagen matrices or oxidized cellulose membrane
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- 59th Medical Wing
Periodontal Diseases
Treatment of Periodontal Intrabony Defects With A-PRF+ or EMD
The aim of this randomized clinical trial was to clinically evaluate and compare the healing of intrabony defects after treatment with advanced platelet-rich fibrin (A-PRF+) to enamel matrix derivatives (EMD) in periodontitis…
- Trial name
- NCT04404374
- Testing
- A-PRF/EMD
- Where
- Hungary
- Volunteers
- 30 people
- Sponsor
- Semmelweis University
Third Molar Surgery
A-PRF AND HA AFTER IMPACTED THIRD MOLAR SURGERY
This randomized controlled clinical trial evaluated the effects of advanced platelet-rich fibrin (A-PRF) and hyaluronic acid (HA) on healing after surgical removal of impacted mandibular third molars.
- Trial name
- NCT07835373
- Testing
- Advanced Platelet-Rich Fibrin, Sodium hyaluronate
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Inonu University
Distal Hypospadias, Hypospadias
Fibrin-Enhanced TIP Versus Grafted TIP Urethroplasty in Distal Hypospadias
Hypospadias is a common congenital condition in boys in which the opening of the urethra is located on the underside of the penis.
- Trial name
- FTIP-RCT (NCT07319780)
- Testing
- Fibrin-Enhanced TIP Urethroplasty, Grafted TIP Urethroplasty
- Where
- 2 sites in Indonesia, Uzbekistan
- Volunteers
- 100 people
- Sponsor
- National Children's Medical Center, Uzbekistan
Periodontitis, Periodontal Attachment Loss
T-PRF Provides Advantages on Periodontal Healing: A Split Mouth Clinical Study
It was aimed to evaluate the contributions of T-PRF treatment combined with open flap debridement on biological markers in GCF and periodontal outcomes in chronic periodontitis patients.
- Trial name
- NCT03027050
- Testing
- T-PRF, Open Flap Debridement alone
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Intrabony Periodontal Defect
Injectable Platelet Rich Fibrin With Demineralized Freeze-dried Bone Allograft in Treatment of Intraosseous Defects
Clinical and radiographic evaluation of injectable platelet rich fibrin (i-PRF) and demineralized freeze-dried bone allograft (DFDBA) compared to demineralized freeze-dried bone allograft (DFDBA) alone in management of…
- Trial name
- NCT03900013
- Testing
- Injectable platelet rich fibrin combined with DFDBA, Demineralized Freeze Dried Bone Allograft
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Neuropathic Pain, Chronic Postsurgical Pain
Efficacy of an Intraoperative Periradicular Application of Platelet Rich Fibrin (PRF) on the Intensity of Residual Post-surgical Neuropathic Pain After a Surgery for Disc Herniation
The prevalence of post-surgical lumbar neuropathic radiculopathy is approximately 30%. Poor response to the treatments recommended for neuropathic pain, namely antidepressants and/or gabapentinoids, requires the development of…
- Trial name
- NeuroPRF (NCT05196503)
- Testing
- Treatment
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Nasal Septum; Deviation, Nasal Septal Srur
Outcomes of PRF on Septoplasty in Patient With Nasal Septal Deviation
The aim of this study is to assess the effectiveness of Platelet-Rich Fibrin (PRF) in improving postoperative healing, reducing complications, and enhancing functional outcomes in patients undergoing septoplasty
- Trial name
- NCT06996106
- Testing
- Effect of Platelet Rich Fibrin on Septoplasty
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Sinus Floor Augmentation, Graftless Sinus Elevation
Fibrin Glue Versus Titanium Platelet-rich Fibrin in Lateral Sinus Lifting
Graftless sinus lift with simultaneous implant placement is one of the new techniques, this new technique is presented based on the physiology of intrasinus bone repair.
- Trial name
- NCT05831267
- Testing
- Fibrin Glue, T-PRF, Negative control
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Hams Hamed Abdelrahman
PRF, Hypospadias
A Multicenter Randomized Controlled Trial Comparing Platelet-Rich Fibrin and Ventral Dartos Flap as Intermediate Layers in Tabularized Incised Plate (TIP) Urethroplasty for Distal Hypospadias With Mild Penile Curvature
Distal hypospadias is the most common form of hypospadias. The Tubularized Incised Plate (TIP) repair is the standard surgical technique for this condition; however, complications such as fistula formation and meatal stenosis…
- Conditions
- PRF, Hypospadias, Distal Hypospadias, Hypospadias Repair
- Trial name
- PRF (NCT07045545)
- Testing
- - Group A: Platelet-rich fibrin membrane prepared intraoperatively and applied over neourethra, Group B: Ventral dartos flap rotated over neourethra
- Where
- Uzbekistan
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- National Children's Medical Center, Uzbekistan
Mucosal Ulceration
Platelet-Rich Fibrin in Intraoral Soft Tissue Regeneration
Determine if the use of platelet rich fibrin (PRF) improves the rate and quality of healing for intraoral mucosal and epithelial soft tissue defects.
- Trial name
- NCT04022720
- Testing
- Platelet Rich Fibrin Application
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Rotator Cuff Tear
Effectiveness of the Ivivi Torino II, Pulsed Radio Frequency Device, on Narcotic Use, Pain and Quality of Life Following Shoulder Arthroscopic Rotator Cuff Repair.
To determine the effectiveness of non-thermal PRF delivered with the Ivivi Torino II on narcotic use, pain, and health-related quality of life following shoulder arthroscopic rotator cuff surgery comparing: Active treatment…
- Trial name
- NCT01507818
- Testing
- Ivivi Torino II
- Where
- 3 sites in United States
- Volunteers
- 37 people
- Sponsor
- Amp Orthopedics, Inc.
Reconstructive Surgery
PRF and Connective Tissue Graft in Interdental Papilla Reconstruction
Interdental papilla deficiency leads to food impaction, problems with phonetics and an unaesthetic appearance. Reconstruction of the deficient papilla is therefore, important.
- Trial name
- NCT03899051
- Testing
- interdental papilla reconstructive surgery with PRF, interdental papilla reconstructive surgery with subepithelial connective tissue graft
- Where
- India
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Edentulous Alveolar Ridge
Implant Placement in Mandibular Molar Xenograft Versus PRF
20 recruited patients indicated for immediate implant placement in mandibular molar patients are divided into 2 groups each group contain 15 patients, one group assigned for placement of bovine bone after molar extraction and…
- Trial name
- NCT03177356
- Testing
- extraction,implant placement,PRF, Exctraction,Implant placement,Bone graft
- Volunteers
- 20 people
- Sponsor
- Cairo University
Wound Healing, Tooth Extraction Site Healing
Effect of Injectable Platelet Rich Fibrin (i-PRF) on Extraction Socket Healing: A Split-Mouth Randomized Study.
The aim of this study is to compare extraction socket healing (SH) following surgical extraction of lower third molars (LTMs) with and without the application of injectable platelet rich fibrine (i-PRF).
- Trial name
- (i-PRF) (NCT07257328)
- Testing
- Surgical extraction of lower third molars.
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Hypospadias
Efficacy of PRF in Hypospadias Repair
Hypospadias is an anomaly characterized by an ectopic ventral urethral meatus, and an incomplete or hooded prepuce. Its incidence is estimated at 1 in 200-300 live male births, with variations across populations and severity…
- Trial name
- NCT07757828
- Testing
- Tubularized Incised Plate urethroplasty with intraoperative placement of autologous PRF onto the urethral plate., standard Tubularized Incised Plate urethroplasty
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Alveolar Cleft
Evaluation of Secondary Alveolar Cleft Reconstruction
The rehabilitation of the disorganized maxilla is the primary objective of secondary alveolar bone grafting (SABG) for alveolar clefts, as the bony reconstruction of the discontinued maxillary arch would permit proper anterior…
- Trial name
- NCT06621719
- Testing
- Alveolar Cleft Reconstruction
- Where
- Egypt
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Periapical Periodontitis, Tooth Diseases
Regenerative Endodontic Procedure of Immature Permanent Teeth With Apical Periodontitis Using PRF
This study evaluates the clinical effect of regenerative endodontic procedure using PRF in immature permanent teeth with apical periodontitis.
- Conditions
- Periapical Periodontitis, Tooth Diseases, Stomatognathic Diseases
- Trial name
- NCT02801552
- Testing
- PRF
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University