Clinical trials: ACL Injuries
ACL Injury
Motor Imagery-Enhanced Rehabilitation Modulates Cortical Plasticity and Functional Recovery After ACL Reconstruction
Part 1: Neural Correlates of Motor Imagery in ACLR Patients This cross-sectional study aims to systematically compare differences in electroencephalographic (EEG) activity between patients who have returned to sport one year…
- Trial name
- NCT07833189
- Testing
- Motor Imagery Therapy (i.e., "mentally practicing movement"), conventional rehabilitation"
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
ACL Tear
Anterior Cruciate Ligament (ACL) Reconstruction With Bone Tendon Bone Autograft With Versus Without Internal Bracing
There is no consensus regarding the best surgical management of primary ACL tears. Recent evidence suggests that internal brace augmentation may increase load failure and therefore stabilize the graft in-situ at the time of ACL…
- Trial name
- NCT05532189
- Testing
- ACL reconstruction with BTB autograft with internal brace augmentation (suture tape), ACL reconstruction with BTB autograft without internal brace augmentation (suture tape), Standardized Rehabilitation Protocol
- Volunteers
- healthy volunteers welcome
- Sponsor
- Columbia University
ACL Injury, Hemodynamics
A Paradigm Shift in Musculoskeletal Rehabilitation Assessment After ACL Reconstruction Using Near-Infrared Spectroscopy
This study aims to establish and compare muscle haemodynamic response patterns in physically active subjects with anterior cruciate ligament (ACL) reconstruction, at different time points after surgery, against healthy controls…
- Conditions
- ACL Injury, Hemodynamics, Oxygen Consumption Based Assessment of Hemodynamics, Exercise
- Trial name
- HemoNIRS-LCA (NCT06621355)
- Testing
- Incremental Interval Test on a Cycle Ergometer
- Where
- Spain
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Universitat de Lleida
Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction
Clinical and Functional Outcomes After ACL Reconstruction Versus Primary Repair
The anterior cruciate ligament (ACL) is the primary structure responsible for controlling anterior-posterior translation and rotational stability of the knee joint.
- Conditions
- Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction, Isokinetic Test
- Trial name
- NCT07318272
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Gazi University
ACL Injuries
Menstrual Cycle-Synced Neuromuscular Training
This is a research study of female athletes participating in at least one running/cutting sport, who have no current conditions that would limit ability to perform sport-like movement tasks (such as running or jumping), and have…
- Trial name
- NCT06983184
- Testing
- MC-synced NTP, Blinded NTP
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Sophia Ulman
ACL - Anterior Cruciate Ligament Rupture
Assessment of NEURO-K-STARTS Following Primary Anterior Cruciate Ligament (ACL) Reconstruction
Anterior cruciate ligament (ACL) reconstruction is the major treatment option for ACL injuries. Despite this, recurrence rates are high.
- Trial name
- NEURO-K-STARTS (NCT07659613)
- Testing
- NEURO-K-STARTS
- Where
- France
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
ACL Injury, ACL Tear
The Pediatric ALL Evaluation and Trial
The overall aim of this multicenter RCT is to determine whether concomitant ALL reconstruction in children undergoing and ACL reconstruction will longitudinally result in a lower rate of graft failure than ACL reconstruction…
- Trial name
- PALLET (NCT04825587)
- Testing
- Patients will be randomized into one of two study arms: (1) concomitant ACL and ALL reconstruction or (2) ACL reconstruction alone.
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
ACL Injury, ACL Reconstruction
Comparative Effectiveness of Blood Flow Restriction With or Without Total Motion Release in ACL Rehabilitation
The aim of this clinical trial is to compare the effectiveness of combined Blood Flow Restriction (BFR) and Total Motion Release (TMR) versus BFR alone in the restoration of muscular strength, balance and knee functionality in…
- Trial name
- BFR-TMR-ACL (NCT07589309)
- Testing
- Blood Flow Restriction, Total Motion Release
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Green International University
ACL Tear, ACL-injury
Do Patients With ACL Tears Demonstrate Weakness of the Soleus Muscle?
The goal of this prospective, cross-sectional study is to test the strength of the soleus muscle in participants who have a ACL tear confirmed by MRI.
- Conditions
- ACL Tear, ACL-injury, ACL - Anterior Cruciate Ligament Rupture
- Trial name
- ACL (NCT06235736)
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
ACL Injury, Anterior Cruciate Ligament Injuries
Baseline ACL Injury Risk Screening and Normative Data
This is a prospective, observational cohort study aimed at establishing a database of normative biomechanics for healthy athletes and surveying these athletes for 12 months following baseline testing for the occurrence of new…
- Conditions
- ACL Injury, Anterior Cruciate Ligament Injuries, Musculoskeletal Injury
- Trial name
- NCT06635668
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Sanford Health
ACL Injury, Hip Injuries
Muscle O2 Saturation and Hemoglobin Levels During Rehabilitation From Arthroscopic Surgery
This study will utilize the Moxy wearable sensor to measure muscle oxygen saturation levels in athletes following lower extremity surgery (ACL or Hip arthroscopy) to evaluate their Return-to-Play.
- Trial name
- NCT05488054
- Testing
- Physical Therapy, Monitored Work-out, Moxy Oxygen Sensor Device
- Where
- 2 sites in United States
- Volunteers
- 226 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
ACL Injury, Kinesiotape
Kinesio Taping for the Knee and Ankle: Acute Impact on Balance, Proprioception, and ACL Risk
This study aims to evaluate and compare the acute effects of Kinesio taping applied to the knee and ankle on balance, proprioception, and anterior cruciate ligament (ACL) injury risk using the Landing Error Scoring System (LESS).
- Conditions
- ACL Injury, Kinesiotape, Balance, Proprioception
- Trial name
- ACL (NCT07138573)
- Testing
- Kinesio Taping (KT) applied to the knee then ankle, Kinesio Taping (KT) applied to the ankle then knee
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
ACL Injury, Stiffness of Knee, Not Elsewhere Classified
Hamstring Stiffness After Anterior Cruciate Ligament Reconstruction
The role of hamstring has been studied in anterior cruciate ligament (ACL) injury prevention, mainly to counteract the anterior tibial translation , especially when contracting eccentrically, but also with passive stiffness.
- Conditions
- ACL Injury, Stiffness of Knee, Not Elsewhere Classified, Sport Injury
- Trial name
- ACLSTIFF (NCT05264597)
- Where
- France
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Anterior Cruciate Ligament (ACL) Injury
The Influence of Demographic Parameters and ACL Injury on the Association Among Clinical, Functional and Biomechanical Parameters
This retrospective study aims at analysing demographics and clinical, functional and biomechanical outcomes in patients after ACL injury (conservative therapy and/or surgery) in patients of different ages and healthy controls.
- Trial name
- MechBRACE (NCT05644275)
- Testing
- Data collection (demographic, clinical, functional and biomechanical outcomes in patients after ACL injury (conservative therapy and/or surgery) in patients of different ages and healthy controls)
- Where
- Switzerland
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
ACL Injuries
Exercise Program for Knee Recovery in Football Players with ACL Injuries
This study aims to evaluate the effectiveness of a structured exercise program in improving knee function, muscle strength, and range of motion in football players recovering from anterior cruciate ligament (ACL) injuries.
- Trial name
- NCT06808763
- Testing
- Knee Rehabilitation Exercise Program
- Where
- Saudi Arabia
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- King Saud University
ACL - Anterior Cruciate Ligament Rupture, Activation Failure
Activation Failure of Knee Extensors After Anterior Cruciate Ligament Rupture Depending on the Contraction Mode
The primary objective of the study is to evaluate the impact of ACL injury and ACL reconstruction on voluntary activation during maximal voluntary contraction (measured by neurophysiological parameters) according to the…
- Conditions
- ACL - Anterior Cruciate Ligament Rupture, Activation Failure, Contraction Mode
- Trial name
- QUADFAIL (NCT06783062)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- La Tour Hospital
ACL, ACL Injury
Acupuncture ACL (Anterior Cruciate Ligament)
Acupuncture research in regards to PONV has been fairly well established, however, studies about perioperative pain control and acupuncture are a little more murky.
- Conditions
- ACL, ACL Injury, Anterior Cruciate Ligament Injury, Anterior Cruciate Ligament Rupture
- Trial name
- NCT03711734
- Testing
- Acupuncture + Standard of Care
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
ACL Injury
MRI Morphology of Femoral Notch in ACL Injury
This study aims to investigate the association between femoral notch morphology, as assessed by MRI, and the risk of ACL injury
- Trial name
- NCT06707285
- Testing
- MRI
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Assiut University
ACL Tear
Effects of Blood Flow Restriction Rehabilitation After Anterior Cruciate Ligament Reconstruction
The study is a prospective randomized control trial consisting of subjects requiring ACL reconstruction with BTB autograft. Subjects were randomly divided into two groups following their inclusion in the study.
- Trial name
- NCT04484961
- Testing
- Blood flow restriction (BFR)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Sports Physical Therapy, Multi-Tasking Behavior
A New Dual Task Test Method for Football Players
Multitasking (Dual Task) is a measurement method to evaluate cognitive ability to execute multiple functions at the same time. To perform this test, while participant/patient performing a main skill (for example, walking), a…
- Conditions
- Sports Physical Therapy, Multi-Tasking Behavior, ACL Injury, Kinesiophobia
- Trial name
- NCT05218993
- Testing
- A new dual-task measurement method with images, A new dual-task measurement method with cards
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University