Clinical trials: ACL Injuries
Anterior Cruciate Ligament Rupture
Intra-articular Administration of 3.0g Tranexamic Acid Has no Effect on Reducing Intra-articular Hemarthrosis and Postoperative Pain After Primary Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial
The purpose of this study was to investigate whether intraarticular administration of tranexamic acid could reduce hemarthrosis and postoperative pain in patients following anterior cruciate ligament reconstruction.
- Trial name
- NCT04042688
- Testing
- intraarticular administration of tranexamic acid
- Where
- South Korea
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
Injury Prevention, Postural Balance
Effects of FIFA 11+ With Dynamic Core Stability Training on Balance and Dynamic Knee Valgus in Amateur Soccer Players
The incidence of soccer-related injuries is reported to have the highest rate amongst all sports. To reduce the incidence of soccer injuries in youth and amateur soccer players, an injury prevention framework namely FIFA 11+ was…
- Trial name
- NCT04958837
- Testing
- FIFA 11+ protocol with additional Core training exercises, FIFA 11+ protocol
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Knee Ligament Injury
TEL and Clam Shell Exercises Affect After ACL
The purpose of this study to determine the effects of the addition of isolated hip strengthening exercises to traditional rehabilitation after Anterior cruciate ligament reconstruction (ACLR).
- Trial name
- NCT05856071
- Testing
- goniometer, clamshells exercises, traditional physical therapy
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Anterior Cruciate Ligament Injuries, Sports Injury
Neuromusculoskeletal Alterations After ACL Injury
This study investigated how anterior cruciate ligament (ACL) injuries affect not only the knee joint but also brain activity, reaction speed, and psychological readiness to return to sports.
- Conditions
- Anterior Cruciate Ligament Injuries, Sports Injury, Neurocognitive Function
- Trial name
- NEURO-ACL (NCT07163468)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Duzce University
ACL - Anterior Cruciate Ligament Rupture
BioACL Reconstruction With Amnion Collagen Matrix Wrap and Stem Cells Case Series
The objective of this study is to evaluate the use of wrapping an ACL graft with a collagen matrix tissue wrap and injecting autologous bone marrow aspirate concentrate under the wrapping and into the graft.
- Trial name
- BioACL(CS) (NCT03294720)
- Testing
- Bio-ACL, amnion wrap and BMAC
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Andrews Research & Education Foundation
Scarring
Medipore Tape Study
This is a prospective, single-blinded, two-arm, randomized, parallel, pragmatic, effectiveness trial that will enroll patients undergoing arthroscopic anterior cruciate ligament reconstruction in order to evaluate the efficacy of…
- Trial name
- NCT02676115
- Testing
- Standard Post Operative Skin Care, Medipore Tape
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
ACL Injury
ADC in Assessing Femoral Tunnel Position
To examine the consistency between postoperative CT scan and intraoperative arthroscopic measurement in evaluating femoral tunnel position for anterior cruciate ligament （ACL）reconstruction，both using the apex of the deep…
- Trial name
- NCT04937517
- Where
- China
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Tear
Magnetic Resonance Imaging and Functional Performance Outcome After ACL Repair With Internal Brace Technique
The purpose of the study is a clinical evaluation with special regard to magnetic resonance imaging and functional performance at least one year after injury / surgery in all three groups (subjects who underwent InternalBrace…
- Trial name
- NCT02760589
- Where
- Austria
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- AUVA
Anterior Cruciate Ligament Injuries, Injuries, Knee
Effects Provided by a Physiotherapy Treatment Preventing Lower Extremity Injuries in Female Football Players
Background and justification: Women's football has a percentage of knee injury of 31.8%, and the anterior cruciate ligament lesion is between 2 and 4 times higher than the male.
- Conditions
- Anterior Cruciate Ligament Injuries, Injuries, Knee, Prevention & Control
- Trial name
- NCT04062578
- Testing
- Physiotherapy program of lumbopelvic stabilization and strengthening of the hip region musculature
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Knee Surgeries, Total Ankle Arthroplasty
Adductor Canal Block With IPACK Versus 4-in-1 Block for Postoperative Analgesia in Knee Surgery
This randomized interventional study compares the analgesic efficacy of Adductor Canal Block combined with Infiltration of the Posterior Capsule of the Knee (IPCAK) versus the 4-in-1 block technique in patients undergoing knee…
- Conditions
- Knee Surgeries, Total Ankle Arthroplasty, Anterior Cruciate Ligament (ACL) Tear, Posterior Cruciate Ligament Tear
- Trial name
- NCT07700797
- Testing
- Adductor canal block with IPACK, 4 in 1 block
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Zagazig University
ACL Injury, Stiffness of Knee, Not Elsewhere Classified
Hamstring Stiffness After Anterior Cruciate Ligament Reconstruction
The role of hamstring has been studied in anterior cruciate ligament (ACL) injury prevention, mainly to counteract the anterior tibial translation , especially when contracting eccentrically, but also with passive stiffness.
- Conditions
- ACL Injury, Stiffness of Knee, Not Elsewhere Classified, Sport Injury
- Trial name
- ACLSTIFF (NCT05264597)
- Where
- France
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Blood Flow Restriction Training, Eccentric Training
BFR Training on Muscle Morphology
This randomized clinical trial study compares high-load eccentric training (HL-Et), sham LL-BFRt, and low-load blood flow restriction (LL-BFRt) in sportsmen.
- Conditions
- Blood Flow Restriction Training, Eccentric Training, Muscle Morphology, Patellofemoral Pain Syndrome
- Trial name
- NCT06566950
- Testing
- Low load-BFRt, High load-Eccentric training
- Where
- Indonesia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Udayana University
Anterior Cruciate Ligament Injuries, Post-Traumatic Osteoarthritis of Knee
Post-Traumatic Knee Osteoarthritis Following Anterior Cruciate Ligament Reconstruction
The purpose of this trial is to define knee joint pathomechanics (KJPM) in the first 2 years after ACL reconstruction (ACLR) and relate these KJPM with changes in articular cartilage morphology and quality.
- Trial name
- NCT06201442
- Testing
- Imaging - magnetic resonance imaging (MRI), Blood sampling, Assessment of functionality and strength
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
ACL Injury
Evaluation of Clinical and Biomechanical Correlation During Return to Sport After Anterior Cruciate Ligament Injury
Comparison of two groups of subjets (ACL injury who return to sport) and control group non-injured about clinical and biomechanical data : clinical test functional test motion analysis of 2 sport exercises tibial translation…
- Trial name
- REPILOG (NCT02686723)
- Testing
- Clinical and biomechanical evaluations
- Where
- France
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Anterior Cruciate Ligament Injury
Maximum Oxygen Uptake in ACL-injured Professional Soccer Players
Our purpose is to evaluate maximum oxygen uptake (VO2max) in ACL-injured professional soccer players and after a six-month period of post-operative rehabilitation, compared to a control group of healthy professional soccer…
- Trial name
- NCT02674282
- Testing
- ACL reconstruction
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Anterior Cruciate Ligament Injuries
Ultrasound Evaluation of Hamstring Tendon Regeneration After ACL Reconstruction and Its Influence
High incidence rate of knee osteoarthritis and gait analysis are important for early assessment of biomechanics. ACL injury is an ideal clinical model for studying knee osteoarthritis.
- Trial name
- NCT04961736
- Testing
- no intervention
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Injuries
Influence of Proprioceptive Reweighting Ability on Lower-limb Biomechanics During Functional Tasks
Anterior cruciate ligament (ACL) injuries are frequent in handball especially among young players. Recent investigations highlighted the implication of the central nervous system as a potential risk factor for ACL rupture.
- Trial name
- NEURIBIO (NCT04736511)
- Testing
- Star Excursion Balance Test, Single leg Drop Vertical Jump, Unplanned sidestep cutting manoeuvre
- Where
- France
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Anterior Cruciate Ligament Injuries, Lower Extremity Problem
Knowledge Translation Intervention for ACL Injury Prevention Program in Youth Soccer
Anterior cruciate ligament (ACL) injuries of the knee are common in youth soccer players, and show an even higher prevalence in female soccer players.
- Trial name
- NCT05442879
- Testing
- Knowledge Translation Intervention, Educational handout
- Where
- United States
- Volunteers
- 671 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Anterior Cruciate Ligament Injury
Nonopioid Analgesia After Anterior Cruciate Ligament Reconstruction
This is a randomized, single blinded, standard of care controlled clinical trial. This project aims to compare postoperative pain control in patients in two treatment arms of anterior cruciate ligament reconstruction: a treatment…
- Trial name
- NCT03818932
- Testing
- Celecoxib, Hydrocodone-Acetaminophen, Ketorolac
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
ACL Injury, Anterior Cruciate Ligament Injuries
Baseline ACL Injury Risk Screening and Normative Data
This is a prospective, observational cohort study aimed at establishing a database of normative biomechanics for healthy athletes and surveying these athletes for 12 months following baseline testing for the occurrence of new…
- Conditions
- ACL Injury, Anterior Cruciate Ligament Injuries, Musculoskeletal Injury
- Trial name
- NCT06635668
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Sanford Health