Clinical trials: ACL Reconstruction
ACL Injury
ADC in Assessing Femoral Tunnel Position
To examine the consistency between postoperative CT scan and intraoperative arthroscopic measurement in evaluating femoral tunnel position for anterior cruciate ligament （ACL）reconstruction，both using the apex of the deep…
- Trial name
- NCT04937517
- Where
- China
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Tear
Magnetic Resonance Imaging and Functional Performance Outcome After ACL Repair With Internal Brace Technique
The purpose of the study is a clinical evaluation with special regard to magnetic resonance imaging and functional performance at least one year after injury / surgery in all three groups (subjects who underwent InternalBrace…
- Trial name
- NCT02760589
- Where
- Austria
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- AUVA
ACL Injury, Stiffness of Knee, Not Elsewhere Classified
Hamstring Stiffness After Anterior Cruciate Ligament Reconstruction
The role of hamstring has been studied in anterior cruciate ligament (ACL) injury prevention, mainly to counteract the anterior tibial translation , especially when contracting eccentrically, but also with passive stiffness.
- Conditions
- ACL Injury, Stiffness of Knee, Not Elsewhere Classified, Sport Injury
- Trial name
- ACLSTIFF (NCT05264597)
- Where
- France
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Anterior Cruciate Ligament Injury
Maximum Oxygen Uptake in ACL-injured Professional Soccer Players
Our purpose is to evaluate maximum oxygen uptake (VO2max) in ACL-injured professional soccer players and after a six-month period of post-operative rehabilitation, compared to a control group of healthy professional soccer…
- Trial name
- NCT02674282
- Testing
- ACL reconstruction
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
ACL
LIVing Donor Allograft for Anterior Cruciate Ligament Reconstruction Study
The Anterior Cruciate Ligament (ACL) is a major stabiliser of the knee. ACL rupture is being increasingly identified in children and skeletally immature patients.
- Trial name
- LivD_ACLR (NCT05395767)
- Testing
- Endoscopic Anterior Cruciate Ligament reconstruction using living donor hamstring allograft from a parent donor
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Maidstone & Tunbridge Wells NHS Trust
Anterior Cruciate Ligament Injuries
Ultrasound Evaluation of Hamstring Tendon Regeneration After ACL Reconstruction and Its Influence
High incidence rate of knee osteoarthritis and gait analysis are important for early assessment of biomechanics. ACL injury is an ideal clinical model for studying knee osteoarthritis.
- Trial name
- NCT04961736
- Testing
- no intervention
- Where
- China
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Anterior Cruciate Ligament Injuries
All-Inside Single-Bundle for Anterior Cruciate Ligament Reconstruction With Full Thickness of the Peroneus Longus Tendon Compared to the Six-strand-hamstring Autograft (ACL)
Anterior cruciate ligament reconstruction is the current gold standard for restoring knee stability. Hamstring tendon (HT) autograft is the most popular graft choice for ACL reconstruction worldwide.
- Trial name
- ACL (NCT05580133)
- Testing
- anterior cruciate ligament reconstruction
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Mongi Slim Hospital
Anterior Cruciate Ligament Rupture
Evaluation of Tibial and Femoral Tunnel Position After Arthroscopic Reconstruction of the Anterior Cruciate Ligament
The purpose of this study is to evaluate the accuracy of tunnel positions in anterior cruciate ligament reconstruction
- Trial name
- NCT01267435
- Testing
- Anterior cruciate ligament reconstruction
- Where
- Iran
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Knee Injuries
Full Vs Partial Weightbearing During the First Six Weeks of Rehab. After Fibular Collateral Ligament Reconstruction
This is a prospective randomized controlled trial with the purpose to determine if patients undergoing fibular collateral ligament (FCL) reconstruction alone or combined FCL and anterior cruciate ligament (ACL) reconstructions…
- Trial name
- NCT05073263
- Testing
- Physical Therapy
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Twin Cities Orthopedics
Injury of the Anterior Cruciate Ligament (ACL)
Clinical and Functional Outcomes 2 Years After ACL Repair and InternalBrace Ligament Augmentation in Comparison With ACL Reconstruction
The aim of this study is to assess the clinical, biomechanical and functional outcome 2 years after anterior cruciate ligament (ACL) repair and InternalBraceTM augmentation now in direct comparison to ACL reconstruction and to…
- Trial name
- RetroBRACE II (NCT04429165)
- Testing
- collection of Patient Reported Outcome (PRO) data, collection of anthropometric and clinical functional data, gait analysis
- Where
- Switzerland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Anterior Cruciate Ligament Reconstruction
Neurophysiologic Correlates of Movement Planning During Complex Jump Landing Tasks and the Role of Cognitive Function
To examine the long-term effects of anterior cruciate ligament injuries and reconstructions (after successful rehabilitation) on cortical processes of motor planning during complex jump landing tasks and the relevance of…
- Trial name
- NCT03336060
- Testing
- Cortical Correlates of Jump Landing Task
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Goethe University
ACL Injury
Effects of HMB Supplementation on Recovery Following ACL Surgery
The anterior cruciate ligament (ACL) is a primary stabilizer of the knee, and thus when ACL injury occurs participation in physical activity is compromised.
- Trial name
- NCT02602561
- Testing
- HMB
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Metabolic Technologies Inc.
Anterior Cruciate Ligament Rupture
Hamstring Muscle Strength After ACL Hamstring Reconstruction
Anterior Cruciate Ligament (ACL) reconstructions using hamstring grafts can be performed using one or two hamstring grafts, the semitendinosus (ST) tendon only, or both the semitendinosus and gracilis (ST/G) tendon.
- Trial name
- HAMSTRING (NCT05464485)
- Testing
- ACL hamstring reconstructions using semitendinosus (ST) tendon only, ACL hamstring reconstructions using semitendinosus and gracilis (ST/G) tendon
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Isala
Pain, Postoperative, ACL
Post Operative Pain Management Through Adductor Canal Block With Bupivacaine for ACL Reconstruction
Liposomal bupivacaine injectable suspension (Exparel), manufactured by Pacira Pharmaceuticals, is an FDA-approved, long-lasting nonopioid analgesic that is indicated for single-dose infiltration in adults to produce postsurgical…
- Trial name
- NCT05161221
- Testing
- OxyCODONE 5 mg Oral Tablet, Naproxen 500 Mg, Tylenol Pill
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
ACL Injury, Meniscus Lesion
Meniscal Lesions in Return to Sport After Anterior Cruciate Ligament Reconstruction
Most athletes who undergo Anterior Cruciate Ligament Reconstruction (ACLR) plan to return to some level of sporting (RTS) activity.
- Conditions
- ACL Injury, Meniscus Lesion, Sport Injury
- Trial name
- LCA-40 (NCT04129827)
- Testing
- Clinical, self-reported psychological and biomechanical assessments
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Bari
Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction
Clinical and Functional Outcomes After ACL Reconstruction Versus Primary Repair
The anterior cruciate ligament (ACL) is the primary structure responsible for controlling anterior-posterior translation and rotational stability of the knee joint.
- Conditions
- Anterior Cruciate Ligament (ACL) Tear, Anterior Cruciate Ligament Reconstruction, Isokinetic Test
- Trial name
- NCT07318272
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Gazi University
Anterior Cruciate Ligament (ACL), Reconstruction
Study of the Isometry of the Anterior Cruciate Ligament From the Center of the Native MRI Insertion Reported on Dynamic Scanner
In anterior cruciate ligament (ACL) reconstruction, navigation and robotic assistance now provide the possibility of precise positioning of the tunnels.
- Conditions
- Anterior Cruciate Ligament (ACL), Reconstruction, Software
- Trial name
- PLANISOLCA (NCT06996145)
- Testing
- dynamic 4D scanner
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
ACL - Anterior Cruciate Ligament Rupture
Prospective Evaluation of Osseous Integration in ACL Reconstruction Comparing Tightrope vs Interference Screw Fixation
The purpose of our study was to compare osseous integration of the bone block in Achilles tendon allograft ACL reconstruction using a cortical button versus biocomposite interference screw fixation.
- Trial name
- NCT03841500
- Testing
- Biocomposite intereference screw femoral tunnel fixation, Endobutton (Tightrope) femoral tunnel fixation
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Kelsey-Seybold Clinic
Osteoarthritis, Knee
MOON Onsite MRI 10 Years After ACL Reconstruction
In this study, a total of 219 subjects from the MOON nested cohort will be studied at CCF, Vanderbilt and OSU, Table 1. Among them, some will have added MRI during their 10-year visit for the MOON study.
- Trial name
- MRI (NCT04660955)
- Testing
- No Intervention - Observational study with MRI
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
ACL Injury, ACL Reconstruction
Comparative Effectiveness of Blood Flow Restriction With or Without Total Motion Release in ACL Rehabilitation
The aim of this clinical trial is to compare the effectiveness of combined Blood Flow Restriction (BFR) and Total Motion Release (TMR) versus BFR alone in the restoration of muscular strength, balance and knee functionality in…
- Trial name
- BFR-TMR-ACL (NCT07589309)
- Testing
- Blood Flow Restriction, Total Motion Release
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Green International University