Clinical trials: ADD
Total Knee Anthroplasty, Knee Osteoarthritis
IPACK vs Adductor Magnus Plane Block Added to Adductor Canal Block for Total Knee Arthroplasty
Total knee arthroplasty (TKA) is among the most frequently performed surgical procedures for degenerative joint diseases, including advanced knee osteoarthritis, rheumatoid arthritis, and post-traumatic arthritis.
- Conditions
- Total Knee Anthroplasty, Knee Osteoarthritis, Postoperative Pain Management
- Trial name
- NCT07643883
- Testing
- ACB+IPACK, ACB+AMM
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Post-traumatic Stress Disorder, Depression
Randomized Control Trial of Group Intervention With Former War-affected Boys in the Democratic Republic of Congo
The purpose of this study is to evaluate, in a randomised control trial (RCT), the effectiveness of group-based, trauma-focused Cognitive Behaviour Therapy (TF-CBT) in reducing psychological distress in former child soldiers and…
- Conditions
- Post-traumatic Stress Disorder, Depression, Conduct Disorder
- Trial name
- NCT01494831
- Testing
- TF-CBT
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Hypercholesterolemia, Coronary Heart Disease
Addition of Phytosterols to a Low Phytosterol Diet
Studies have shown that phytosterols will lower LDL cholesterol. Typical diets can contain between 250 to 500 mg of naturally-occurring phytosterols.
- Trial name
- phyteaux-I (NCT00860054)
- Testing
- Different amount of phytosterols are added into diets
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Iron Deficiency Anemia
Iron Deficiency Anemia and Psychosocial Stimulation
In developing countries, poor nutrition, high morbidity, poverty, poor parental education and stimulation in the home, all detrimentally affect children's development.
- Trial name
- IDA (NCT00668694)
- Testing
- Stimulation
- Where
- Bangladesh
- Volunteers
- 434 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Attention-Deficit Hyperactivity Disorder
Johnston County ADHD Study: Environmental, Reporductive, and Familial Risk Factors for Attention-Deficit Hyperactivity Disorder (ADHD)
We propose a population-based case-control study among 7000 elementary school children in semi-rural Johnston County, NC. Teachers will complete a screening form on each child. Controls will be randomly selected.
- Trial name
- NCT00339729
- Where
- United States
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Obesity and Obesity-related Medical Conditions
Effect of Betaine and Choline on Metabolic Health
The purpose of this research is to determine whether extra betaine and choline influence metabolic health in adults with overweight and obesity.
- Trial name
- NCT06758856
- Testing
- Trimethylglycine, Eggs, Cellulose
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Guelph
Bowel Preparation Quality
The Impact of Additional Oral Preparation on the Quality of Bowel Preparation for Colonoscopy
Although adequate bowel preparation is essential for successful colonoscopy, the 23% of patients had shown inadequate bowel preparation.
- Trial name
- NCT02540031
- Testing
- Additional oral preparation (3L of PEG+Asc, "Coolprep®"), Standard oral preparation (2L of PEG+Asc, "Coolprep®")
- Where
- South Korea
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Kyungpook National University Hospital
Attention-deficit/Hyperactivity Disorder
Language-based Learning Skills and Attention Deficit Hyperactivity Disorder (ADHD): Impact of Treatment With Sustained-release Guanfacine
This study is investigating the effect of sustained-release guanfacine (Intuniv) on language-based learning skills in children age 6-12 who are diagnosed with attention deficit hyperactivity disorder (ADHD).
- Trial name
- NCT01146002
- Testing
- Guanfacine (sustained release)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Neurology Group of Bergen County, P.A.
Obesity
The Reinforcing Value of Added Sugars
The purpose of this study is to determine how daily diet relates to eating choices.
- Trial name
- NCT02744001
- Testing
- Low Added Sugar Diet
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- USDA Grand Forks Human Nutrition Research Center
Anesthesia
Effects of Low Dose Neuromuscular Blocker Usage on Laryngeal Mask Application
Cystoscopy is a simple, effective and reliable method in current urological practice. Anesthesia may be required in cystoscopy for therapeutic purpose, however it may not be necessary for diagnostic cystoscopy.
- Trial name
- NCT03424356
- Testing
- Rocuronium Bromide, Saline Solution, Fentanyl
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Attention Deficit/Hyperactivity Disorder (ADHD)
Treatments for Fathers With ADHD and Their At-Risk Children (Fathers Too)
In contrast to mothers with Attention Deficit/Hyperactivity Disorder (ADHD), the impact of paternal ADHD in families and children with ADHD symptoms has not been studied, despite the prevalence of ADHD in males.
- Trial name
- NCT02675400
- Testing
- Vyvanse, Behavioral Parent Training, Methylphenidate
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Seattle Children's Hospital
Presbyopia
Clinical Assessment of a Customized Free-form Progressive Addition Lens Spectacle
The purpose of this study was to compare objective clinical measures of visual performance and subjective measures of satisfaction and preference between standard progressive addition lens (PAL) spectacles and a new type of…
- Trial name
- CZV_PAL1 (NCT01234207)
- Testing
- Standard, non-free-form, non-customized PAL spectacles, Individually customized free-form surfaced PAL spectacles
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Anesthesia; Functional
Effects of Analgesics in Cesarean Section Elective
Two approved treatments for spinal anesthesia will be compared in women undergoing cesarean section. It is usual to perform cesarean sections using spinal anesthesia with a local anesthetic (bupivacaine) plus some opioid, such as…
- Trial name
- CES (NCT03386630)
- Testing
- Hyperbaric bupivacaine+Sufentanil, Hyperbaric bupivacaine+Morphine
- Where
- Spain
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Fundación Pública Andaluza Progreso y Salud
Cardiovascular Disease, Diabetes
Diet and Activity Promotion Among Older Working Adults
The trial will test whether the Alive email-delivered health behavior program can improve subjects' physical activity, fruits and vegetables and saturated/trans fats and added sugars.
- Conditions
- Cardiovascular Disease, Diabetes, Obesity, Aging
- Trial name
- ALIVE (NCT01233063)
- Testing
- Physical Activity and Diet Intervention via Alive2
- Where
- United States
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- Berkeley Analytics, Inc.
Attention Deficit Hyperactivity Disorder
Disturbed Structural Connectivity of Frontostriatal and Frontoparietal Networks in Adults With ADHD
Attention deficit/hyperactivity disorder (ADHD) is a common, impairing, childhood onset neuropsychiatric disorder with executive dysfunctions. The ADHD symptoms and executive deficits may last to adulthood.
- Trial name
- NCT02232464
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Iron Absorption
Iron Absorption From an Iron-fortified Follow-up Formula With Added Synbiotic or Human Milk Oligosaccharides
The co-primary objectives of this study are: 1) to investigate the effect adding a synbiotic (combination of a pre-and probiotic) to iron-fortified follow-up formula (FUF) on iron bioavailability, and 2) to investigate the effect…
- Trial name
- NCT04774016
- Testing
- Test formula A without added pre- and pro-biotic, Test formula B with synbiotic, Test formula C with HMOs
- Where
- Thailand
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Attention Deficit Hyperactivity Disorder
Neurocognitive Exercise Program for Children With Attention Deficit and Hyperactivity Disorder
The effects of Neurocognitive Exercise Program (NEP) on ADHD symptoms and executive functions in children with Attention Deficit and Hyperactivity Disorder (ADHD) will be investigated using The Conners parent rating scale-revised…
- Trial name
- NCT04707040
- Testing
- Neurocognitive Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Hypothyroidism
The Yield of Postnatal Thyroid Function Test in the Well Baby Nursery
Thyroid function test are performed in the well baby nursery to newborn infants of mothers with hypothyroidism, or as part of neonatal jaundice investigation.
- Trial name
- NCT05033496
- Testing
- Thyroid function test
- Where
- Israel
- Volunteers
- 40,601 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Fragile X Syndrome
Add-on Pilot Trial of Minocycline to Treat Fragile X Syndrome
Fragile X Syndrome (FXS) is the most common known inherited form of mental impairment, developmental disability and autism. Minocycline is an antibiotic that has recently been used to treat the mouse model for Fragile X, and was…
- Trial name
- NCT00858689
- Testing
- Minocycline
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- FRAXA Research Foundation
Bipolar Depression
Treatment Resistant Bipolar Depression
To determine if adding Escitalopram to current mood stabilizer (MS) or atypical antipsychotic (AA) will improve in rates similar to or better than adding a placebo (inactive pill)in resistant bipolar patients.
- Trial name
- NCT00272025
- Testing
- Escitalopram
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Queen's University
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