Clinical trials: AI
Lung Disease
Spirometry Interpretation Performance of Primary Care Clinicians With/Without AI Software
To evaluate whether an artificial intelligence decision support software (ArtiQ.Spiro) improves the diagnostic accuracy of spirometry interpreted by primary care clinicians, as measured by Clinician Diagnostic Accuracy (vs…
- Trial name
- SPIRO-AID (NCT05933694)
- Testing
- Artificial Intelligence-powered Spirometry Interpretation Report
- Where
- United Kingdom
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Physical Inactivity, Aging
Motivating Activity Through Text Communications - Helping Adults Increase Movement
The goal of this clinical trial is to compare the effect of different types of text messages on physical activity levels of middle-aged and older adults and to determine whether these messages are effective in adults age 40 and…
- Conditions
- Physical Inactivity, Aging, Cognitive Ability, Behavior Change
- Trial name
- MATCH AIM (NCT07593677)
- Testing
- Text Messaging Intervention
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Michigan
AI-Assisted Diagnosis, Large Language Models
Improving AI-Assisted Medical Diagnosis and Triage by the General Public
This study is a randomized controlled trial (RCT) investigating whether access to a new LLM interface can improve medical triage and diagnostic accuracy for laypeople compared to access to a standard LLM interface.
- Trial name
- NCT07728513
- Testing
- new GPT-4o Interface, Control
- Where
- Pakistan
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Lahore University of Management Sciences
Healthcare Provider Well-being
Ambient AI for Provider Well-Being
The goal of this clinical trial is to learn whether using Ambient Artificial Intelligence for provider documentation will enhance provider well-being and improve documentation quality.
- Trial name
- NCT06517082
- Testing
- Artificial Intelligence
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Healthy Volunteer
A Study to Evaluate the Bioequivalence of Tocilizumab Following Subcutaneous Administration Via an Autoinjector (AI 1000-G2) Versus a Pre-Filled Syringe in Healthy Volunteers
The study consists of an eligibility screening period, two study periods involving single doses of tocilizumab (TCZ) according to an open-label, randomized, two-period crossover design with an interval of 6 weeks between periods…
- Trial name
- NCT02678988
- Testing
- AI-1000 G2, PFS-NSD, Tocilizumab
- Where
- 3 sites in United States
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Congenital Anomalies, Neonatal Complications
AI-Powered Neonatal Risk Assessment for Improved Perinatal Outcomes
This study aims to develop advanced artificial intelligence (AI) models that predict neonatal risks and complications based on historical multimodal health data, including ultrasound and MRI scans.
- Conditions
- Congenital Anomalies, Neonatal Complications, Perinatal Outcomes, Perinatal Outcomes of the Mother and Fetus
- Trial name
- NCT07064356
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- FetalFirst Limited
Intensive Care Unit-acquired Weakness, Artifical Intelligence
AI Based Muscular Ultrasound to Assess Intensive Care Unit-acquired Weakness
The aim of this observational case-control study is to investigate, whether artificial intelligence can detect ultrasound-derived imaging characteristics typical for intensive care unit-acquired weakness.
- Conditions
- Intensive Care Unit-acquired Weakness, Artifical Intelligence, Ultrasound
- Trial name
- ACTIVATE (NCT06765551)
- Testing
- Neuromuscular Ultrasound
- Where
- Germany
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Jena University Hospital
Depressive Symptoms, Mental Health (Depression)
Using a School-Based Depression Literacy Psychoeducation Program With AI Chatbot to Improve Depression Literacy and Help-Seeking Among High School Students
The primary purpose of this randomized controlled trial is to evaluate the effectiveness of an AI chatbot enhanced school-based depression literacy psychoeducational program, combined with a resource navigation booklet, on high…
- Trial name
- NCT07790731
- Testing
- school-based depression literacy program
- Where
- Taiwan
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Chang Hsiu-Ju
Lung Cancer
AI-Driven Precision Diagnostic System for Lung Cancer Based on Liquid Biopsy
The investigators aim to develop an AI-powered precision medicine system based on liquid biopsy that can comprehensively provide lung cancer patients with information on disease stage, histologic subtype, and presence of genetic…
- Trial name
- NCT07009769
- Where
- South Korea
- Volunteers
- 865 people, healthy volunteers welcome
- Sponsor
- Korea University Guro Hospital
Systemic Health Risk
AI-Assisted Systemic Health Risk Assessment in General Ophthalmology
This study will evaluate whether providing ophthalmologists with additional artificial intelligence (AI)-assisted health risk information derived from routine retinal images affects subsequent clinical care in adults attending…
- Trial name
- LifeEye-RCT (NCT07890922)
- Testing
- AI-Assisted Health Risk Information
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Artificial Intelligence, Qualitative Research
Qualitative Research Among Physicians and Junior Doctors Into the Preconditions for Implementing a CDSS Based on AI in the ICU
The goal of this study is to explore the different attitudes and preconditions of potential end-users (doctors \& physicians in training) required to achieve successful clinical implementation of models based on artificial…
- Conditions
- Artificial Intelligence, Qualitative Research, Decision Support Systems, Clinical
- Trial name
- KATRINA (NCT05303025)
- Testing
- Survey, Semi-structured group discussion
- Where
- 3 sites in Belgium
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University Ghent
Dental Education, Artificial Intelligence (AI)
AI Virtual Patient Training for Dental Student History Taking
This randomized study evaluated whether an artificial intelligence-assisted virtual patient could support third-year dental students in practicing medical and dental history taking.
- Conditions
- Dental Education, Artificial Intelligence (AI), Virtual Patient, History Taking
- Trial name
- NCT07688668
- Testing
- Gemini-Based AI Virtual-Patient Training, Conventional Role-Play Training
- Where
- Vietnam
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Hue University of Medicine and Pharmacy
Medical Student
AI-Assisted Learning in Medicine
This multi-center retrospective cohort study investigates the real-world impact of integrating MetaGP-Edu, a proprietary AI tool fine-tuned for medical education, into the undergraduate Internal Medicine curriculum.
- Trial name
- NCT06945159
- Where
- 2 sites in China
- Volunteers
- 1,632 people, healthy volunteers welcome
- Sponsor
- Kang Zhang
Healthy Participants
A Study Comparing Two Subcutaneous Formulations: Vial and Autoinjector (AI) With Olezarsen, at Two Dose Levels, in Healthy Adult Participants
The purpose of the study is to assess the bioequivalence of olezarsen between 2 subcutaneous (SC) formulations [(autoinjector (AI) and vial] at 2 dose levels in healthy adult participants.
- Trial name
- NCT05579860
- Testing
- Olezarsen
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Ionis Pharmaceuticals, Inc.
Artificial Intelligence, Endoscopy
AI-assisted Endoscopy Report System In Improving Reporting Quality
In this study, we proposed a prospective study about the effectiveness of artificial intelligence system for endoscopy report quality in endoscopists. The subjects would be divided into two groups.
- Trial name
- NCT05479253
- Testing
- Artificial intelligence assistant system
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Renmin Hospital of Wuhan University
Cardiopulmonary Exercise Test Interpretation
AI-Assisted Anaerobic Threshold Interpretation in Cardiopulmonary Exercise Testing
This prospective randomized two-period crossover reader study will evaluate whether assistance from a frozen artificial intelligence model improves physicians' interpretation of the anaerobic threshold (AT) in cardiopulmonary…
- Trial name
- PACE-Reader (NCT07833137)
- Testing
- AI-Assisted Anaerobic Threshold Interpretation, Unassisted Cardiopulmonary Exercise Test Interpretation
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Diabetes
AI-Based Lifestyle Guidance Study
The X Life model is an innovative AI-based lifestyle guidance system designed to provide tailored health management recommendations for individuals with T2DM or prediabetes, leveraging continuous glucose monitoring (CGM) data…
- Trial name
- NCT07160972
- Testing
- Lifestyle Management
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Li Huating
Ultrasound Imaging of Anatomical Structures
Data Collection for the Validation of an Artificial Intelligence Software to Support Musculoskeletal Ultrasound Examination
This study conducted at three locations, aiming to collect ultrasound images from volunteers and assess the performance of an AI software, MSK Go, using these images.
- Trial name
- NCT07336407
- Testing
- Ultrasound Scans
- Where
- 3 sites in United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Smart Alfa Teknoloji San. ve Tic. A.S.
MASLD, Pediatric
Ultrasound-Based Estimation of Hepatic Steatosis in Pediatric MASLD
The purpose of this study is to validate an artificial intelligence (AI)-based algorithm that estimates hepatic steatosis using ultrasound (US) B-mode images in pediatric participants with metabolic dysfunction-associated…
- Trial name
- NCT07265011
- Testing
- Ultrasound and MRI
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Jae Won Choi
Hyperlipidemia, Medication Nonadherence
AdLip: Human Coach-supported Digital/AI Personal Health Assistant to Improve Adherence to Lipid-Lowering Medication
Investigators hypothesize that the use of a human coach-supported digital/AI personal health assistant (app) will improve adherence to cholesterol-lowering medications (statins with or without ezetimibe) among patients with…
- Trial name
- AdLip (NCT06614049)
- Testing
- Human Coach-supported Digital/AI Personal Health Assistant to Improve Adherence to Lipid-Lowering Medications
- Where
- 2 sites in Singapore
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- National University of Singapore