Clinical trials: AI Chatbot
Peri-Implant Mucositis, Peri-implantitis
Impact of an AI-Based Chatbot on Implant Patient Management: RCT
Background: Dental implant therapy is a well-established and predictable procedure for replacing missing teeth, with high long-term survival rates.
- Conditions
- Peri-Implant Mucositis, Peri-implantitis, Peri-Implant Health, Peri-implant Inflammation
- Trial name
- NCT07300657
- Testing
- AI Chatbot, Standard Oral Hygiene Education
- Where
- Italy
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Catania
Normal Labor
Generative AI-Powered Intrapartum Clinical Decision Support Among Healthcare Providers
Pregnancy and childbirth are uniquely important events in women's lives because they are accompanied by major physical, emotional, and psychological changes.
- Trial name
- NCT07720531
- Testing
- Generative AI-Powered Intrapartum Chatbot
- Where
- Egypt
- Volunteers
- 427 people, healthy volunteers welcome
- Sponsor
- Delta University for Science and Technology
Control Condition, Intervention
Effectiveness of AI Chatbots in Improving Students' General Wellbeing
The goal of this randomised controlled trial is to evaluate the effectiveness of an AI mental health chatbot in promoting emotional wellbeing and perceived empathy among university students in Singapore with mild or subclinical…
- Trial name
- NCT06965439
- Testing
- AI-delivered emotional wellbeing support, Neutral writing tasks
- Where
- Singapore
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Patient Health Information Seeking Behavior, Trust
Patient AI Trust Dynamics Before and After Orthopedic Consultation (ORTHO-OP-GPT)
Patients increasingly consult artificial intelligence (AI) chatbots such as ChatGPT for health information before clinical visits, yet the impact of an actual orthopedic consultation on patient trust in AI-derived information…
- Conditions
- Patient Health Information Seeking Behavior, Trust, Health Literacy, Orthopedics
- Trial name
- ORTHO-OP-GPT (NCT07631585)
- Where
- 2 sites in Cyprus
- Volunteers
- 350 people
- Sponsor
- Utku Gürhan
Cardiovascular-kidney-metabolic Syndrome
AI Chatbot-Enabled ePRO Monitoring and Nurse-Led Self-Management for Early-Stage Cardiovascular-Kidney-Metabolic Syndrome
This randomized controlled trial will evaluate the effectiveness of an AI chatbot-enabled electronic patient-reported outcome (ePRO) monitoring and nurse-led self-management intervention for adults with early-stage…
- Trial name
- NCT07577284
- Testing
- AI chatbot-enabled nurse-led program., Usual Care
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taipei Medical University
Type 2 Diabetes, Type 2 Diabetes Mellitus (T2DM)
Fitbit and AI Chatbot in Sedentary Primary Care Patients With T2D
The goal of this observational study is to evaluate the feasibility and acceptability of a 12-week intervention utilizing a Fitbit and artificial intelligence (AI)-delivered diabetes self-management education and support (DSMES)…
- Conditions
- Type 2 Diabetes, Type 2 Diabetes Mellitus (T2DM), T2DM (Type 2 Diabetes Mellitus), T2D
- Trial name
- FIT T2D (NCT07005362)
- Testing
- Fitbit and AI Chatbot, Routine Care
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Colorado, Denver
Physical Activity
Self-directed Use of Resources for Physical Activity
This is a pilot RCT examining physical activity outcomes at 3 months across 3 conditions: use of large language model (LLM) fully self-directed; use of LLM with guidance; and use of online tools to help with sleep.
- Trial name
- CHARGE (NCT07654868)
- Testing
- LLM alone, LLM enhanced, Sleep promotion
- Volunteers
- 39 people
- Sponsor
- University of Florida
Healthy Lifestyle
A Pilot Randomized Controlled Trial of Chatbot Use in Older Adults for Lifestyle Change
The purpose of this study is to evaluate the acceptability and preliminary effectiveness of a smartphone-delivered AI-based chatbot in promoting healthy dietary behavior and physical activity participation among older adults.
- Trial name
- NCT06901037
- Testing
- A chatbot-based intervention
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Osteoporosis, Sarcopenia
Osteoporosis and Sarcopenia Prevention in Middle-Aged Population
This initiative is designed to yield substantial and multi-level benefits for the Hong Kong community by pioneering a transformative model of preventive healthcare.
- Trial name
- FORTIFY (NCT07611097)
- Testing
- Intervention Group, Control Group
- Where
- Hong Kong
- Volunteers
- 8,336 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Depressive Disorder, Depressive Symptoms
AI Mental Health Tool vs. Psychoeducation Control
The goal of this clinical trial is to learn if Ash, an AI chat tool for mental health, works better than static psychoedcuation in reducing mental health symptoms.
- Trial name
- NCT07841483
- Testing
- Ash, Psychoeducation
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Slingshot AI
Smoking Cessation
Gen AI Powered Behavioral Support Plus Chewing Gum Intervention for Construction Workers Who Smoke
The goal of this pilot trial is to learn if 1-week NRT sampling, 3-week chewing gum, and 12-week chatbot-delivered instant messaging support works to help smoking cessation in construction workers who smoke.
- Trial name
- NCT07649018
- Testing
- AWARD advice, Brief leaflet on health warning and smoking cessation, Referral card
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- The University of Hong Kong
Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Reflects the Intervention (AI Chatbot)
The goal of this clinical trial is to investigate the impact of an AI-powered chatbot intervention on improving knowledge, attitudes, and empowerment in breast cancer patients.
- Trial name
- BC-CHAT (NCT06943911)
- Testing
- AI Chatbot for Breast Cancer Patient Education and Empowerment
- Where
- Egypt
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Mostafa Shaban
Healthy
Building Cognitive Resilience to Vaccine Misinformation Using AI: Evidence From a Randomised Trial
This study aims to understand how parents and caregivers in the United Kingdom engage with information about childhood vaccination (routine vaccines for children and adolescents, excluding tetanus or international travel-related…
- Trial name
- NCT07488962
- Testing
- AI-driven chatbot, Social media infographic
- Where
- United Kingdom
- Volunteers
- 1,008 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Pelvic Floor Disorder, Loneliness
Postpartum Education Via Artificial Intelligence for Recovery and Loneliness: A Randomized Controlled Trial
The goal of this clinical trial is to learn whether a postpartum chatbot powered by generative artificial intelligence (genAI) can help new mothers get better pelvic floor health information and feel less lonely after childbirth.
- Conditions
- Pelvic Floor Disorder, Loneliness, Postpartum, Mental Health
- Trial name
- PEARL (NCT07223736)
- Testing
- Generative artificial intelligence (genAI) postpartum chatbot, Standard of Care (SOC)
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- University of California, San Diego
Caregivers
Feasibility and Acceptability of an LLM-based Chatbot for Family Caregivers: Evaluation Study
This study evaluates the feasibility and acceptability of using the artificial intelligence (AI) chatbot mobile application (an LLM-based Chatbot) to support the well-being of informal care partners of individuals with traumatic…
- Trial name
- NCT07280650
- Testing
- LLM-based Chatbot
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Michigan
Healthy
Building Cognitive Resilience to Vaccine Misinformation Using AI in Europe
This multi-country trial evaluates an AI chatbot designed to counter cognitive biases and inoculate parents against vaccine misinformation, embedded within a large survey across five European countries (n=5,000).
- Trial name
- NCT07551986
- Testing
- AI-driven chatbot, Social media infographic
- Where
- United Kingdom
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Psychological Stress, Perceived Stress
A Persian AI-Based CBT Chatbot and Voice Analysis System for Managing Perceived Stress
This pilot randomized controlled trial aims to evaluate a Persian-language artificial intelligence (AI)-based cognitive behavioral therapy (CBT) chatbot designed to support adults in managing perceived stress.
- Trial name
- PersianAI-CBT (NCT07840469)
- Testing
- Persian AI-Based CBT Chatbot, Active Mental Health Content
- Where
- Iran
- Volunteers
- 120 people
- Sponsor
- Hamid Reza Marateb
Social Needs Status, Unmet Health-Related Social Needs and Access to Community Resources
AI-Based Personalized Health and Self-Care
The goal of this clinical trial is to learn if the DAPHNE chatbot can improve caregiver engagement, usability, and integration of social care support tools into clinical workflows in caregivers of pediatric patients receiving…
- Conditions
- Social Needs Status, Unmet Health-Related Social Needs and Access to Community Resources, Primary Health Care and Access to Primary Care, Technology Use to Support Caregivers
- Trial name
- NCT07168382
- Testing
- DAPHNE Chatbot Intervention, Standard HRSN Screening and Referral (Usual Care)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Emre Sezgin
Hyperglycaemia, Hypertension
Developing an AI Pharmacy Chatbot for the Population of Hong Kong
The primary objective of this study is to is to develop a conversational AI service (chatbot) in Hong Kong to assist patients and caregivers with inquires related to Hospital Authority (HA)-prescribed medications, and to evaluate…
- Conditions
- Hyperglycaemia, Hypertension, Hyperlipidaemia, Artificial Intelligence (AI)
- Trial name
- NCT07037563
- Testing
- An AI pharmacy chatbot offering information related to HA-prescribed medication for hyperglycaemia, hypertension, and hyperlipidaemia
- Where
- 2 sites in Hong Kong
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
AI Chatbot, Cardiovascular (CV) Risk
Effect of a Web-based Application With Integrated AI Chat for Cardiovascular Risk Support
To determine the effect of a web-based application with an integrated AI chat module on 10-year cardiovascular risk score (intervention) versus usual clinic care (control) after 3 months from baseline score.
- Trial name
- NCT07917000
- Testing
- web application with AI chat, usual clinic care follows the national prevention and management guidelines for major cardiovascular risk factors
- Volunteers
- 116 people
- Sponsor
- Cairo University