Clinical trials: AI Chatbot, open to volunteers
Hereditary Cancer Syndromes
Feasibility Study of a Chatbot AI-Driven Preliminary Screening System for Hereditary Cancer Syndromes
This study aims to assess the feasibility of implementing an AI-based hereditary cancer preliminary screening system that has already been developed.
- Trial name
- NCT07901543
- Testing
- Hereditary cancer preliminary screening chatbot
- Where
- Singapore
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Cancer Centre, Singapore
Chronic Low-back Pain (cLBP), Non-specific Low Back Pain (NSLBP)
Hybrid mHealth for Low Back Pain
The goal of this clinical trial is to evaluate whether adding a WhatsApp-based AI chatbot to standard physiotherapy and psychological care can improve self-management and outcomes in adults aged 18-65 with chronic low back pain…
- Trial name
- NCT07902778
- Testing
- Face-to-face physiotherapy and psychological care (for hybrid arm), WhatsApp-based AI chatbot for self-management (for hybrid and WhatsApp-only arms), Face-to-face physiotherapy and psychological care (No Digital Support) (for control arm)
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The Hong Kong Polytechnic University
Therapeutic Communication
Culturally-Tailored AI Chatbot Simulation for Therapeutic Communication and Empathy in Psychiatric Nursing Students
Therapeutic communication and empathy are core competencies in psychiatric nursing, yet students often have limited opportunities to practise them safely with culturally realistic patients and families.
- Trial name
- AI-CHAT-PSY (NCT07905469)
- Testing
- Culturally-Tailored AI Chatbot Simulation, Instructor-Facilitated Peer Role-Play
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Sarcoma
Information-providing Chatbot
This study aims to develop and examine the feasibility and preliminary effectiveness of an AI-based sarcoma chatbot building on ChatGPT (ASCC) to address the information needs of sarcoma patients.
- Trial name
- NCT07505732
- Testing
- ASCC (sarcoma-specific AI chatbot), Routine Clinical Care
- Volunteers
- 78 people
- Sponsor
- The Hong Kong Polytechnic University
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
An Artificial Intelligence-Powered Supportive Care Chatbot to Address the Supportive Care Needs of Young Adult Cancer Survivors
This clinical trial studies whether an artificial intelligence (AI)-powered supportive care chatbot is helpful for addressing the supportive care needs of young adult cancer survivors.
- Trial name
- NCT07772596
- Testing
- Artificial Intelligence-based Intervention, Interview, Survey Administration
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan Rogel Cancer Center
Aged, Exercise
Development of a Chatbot-supported Personalized Exercise Program for Older Adults and Evaluation of Its Effects on Cognitive Functions
The purpose of this study is to develop an artificial intelligence-based chatbot application to support exercise behavior in individuals aged 60 and over who do not regularly exercise, and to evaluate its effectiveness.
- Conditions
- Aged, Exercise, Cognition, Artificial Intelligence (AI)
- Trial name
- NCT07596082
- Testing
- Artificial intelligence-supported chatbot
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dokuz Eylul University
Prostate Cancer Patients
AI Chatbot for Prostate Radiation Therapy Patient Education
This study will evaluate whether an artificial intelligence chatbot can help patients better understand radiation therapy for localized prostate cancer.
- Trial name
- NCT07719062
- Testing
- AI Educational Chatbot
- Volunteers
- 50 people
- Sponsor
- Brigham and Women's Hospital
Digital Health Literacy, AI Chatbot
Artificial Intelligence and Digital Health Literacies Among Older Adults: A Mixed-method Pilot Intervention Study
The goal of this pilot study is to determine the feasibility and to learn if a training program called E2NGAGE-Literacy (Empowering Elders in Navigating Generative AI for Greater E-health Literacy) can potentially help older…
- Conditions
- Digital Health Literacy, AI Chatbot, Aged 60 Years or Older
- Trial name
- NCT07881510
- Testing
- AI and digital health literacy program (E2NGAGE-Literacy)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Depressive Symptoms, Mental Health (Depression)
Using a School-Based Depression Literacy Psychoeducation Program With AI Chatbot to Improve Depression Literacy and Help-Seeking Among High School Students
The primary purpose of this randomized controlled trial is to evaluate the effectiveness of an AI chatbot enhanced school-based depression literacy psychoeducational program, combined with a resource navigation booklet, on high…
- Trial name
- NCT07790731
- Testing
- school-based depression literacy program
- Where
- Taiwan
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Chang Hsiu-Ju
Stress (Psychology)
Effectiveness of A Mindfulness-centered Stress Management AI Chatbot to Reduce Stress and Enhance Mental Health Among Men Who Have Sex With Men in China
The goal of this randomized controlled trial is to evaluate the effectiveness of a mindfulness-centered stress management AI chatbot in reducing perceived stress and enhancing mental health among Chinese men who have sex with men…
- Trial name
- MSM (NCT07732621)
- Testing
- Mindfulness-centered stress management AI chatbot, Psychoeducation
- Where
- Hong Kong
- Volunteers
- 76 people
- Sponsor
- The University of Hong Kong
Diabetes, Gestational, Pre-eclampsia
Usability Evaluation of Gen AI-based Nutrition Chatbot for Pregnant Women
Background: Pregnancy imposes significant physical demands, with complications like gestational diabetes (GDM) and pre-eclampsia posing serious risks.
- Conditions
- Diabetes, Gestational, Pre-eclampsia, AI Chatbot for Prenatal Nutrition Guidance
- Trial name
- NCT07458997
- Testing
- a culturally tailored nutrition AI chatbot for pregnant women
- Where
- Hong Kong
- Volunteers
- 100 people
- Sponsor
- Hong Kong Metropolitan University
Caregivers
Feasibility and Acceptability of an LLM-based Chatbot for Family Caregivers: Evaluation Study
This study evaluates the feasibility and acceptability of using the artificial intelligence (AI) chatbot mobile application (an LLM-based Chatbot) to support the well-being of informal care partners of individuals with traumatic…
- Trial name
- NCT07280650
- Testing
- LLM-based Chatbot
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Michigan
Mild Cognitive Impairment (MCI), Social Isolation
AI-CONECT: A Conversational AI for Early Dementia Prevention in Socially-Isolated Older Adults
This randomized controlled trial examines the mechanisms of conversational AI-based interventions for early dementia prevention in socially isolated older adults.
- Trial name
- AI-CONECT (NCT07701668)
- Testing
- AI-based conversational intervention
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Massachusetts General Hospital
Physical Activity
Self-directed Use of Resources for Physical Activity
This is a pilot RCT examining physical activity outcomes at 3 months across 3 conditions: use of large language model (LLM) fully self-directed; use of LLM with guidance; and use of online tools to help with sleep.
- Trial name
- CHARGE (NCT07654868)
- Testing
- LLM alone, LLM enhanced, Sleep promotion
- Volunteers
- 39 people
- Sponsor
- University of Florida
Smoking Cessation
Gen AI Powered Behavioral Support Plus Chewing Gum Intervention for Construction Workers Who Smoke
The goal of this pilot trial is to learn if 1-week NRT sampling, 3-week chewing gum, and 12-week chatbot-delivered instant messaging support works to help smoking cessation in construction workers who smoke.
- Trial name
- NCT07649018
- Testing
- AWARD advice, Brief leaflet on health warning and smoking cessation, Referral card
- Where
- Hong Kong
- Volunteers
- 200 people
- Sponsor
- The University of Hong Kong
Healthy
Chatbot Intervention Effects on Social and Monetary Incentive Processing in Anhedonia
The main aim of the present study is to investigate the effects of a Motivational Interviewing-based artificial intelligence chatbot on social incentive processing in college students with elevated levels of depression and…
- Trial name
- NCT07665242
- Testing
- MI Chatbot Interaction, Active Control Chatbot Interaction
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Oral Cancer, Chatbot
Enhancing Oral Cancer Awareness
To evaluate the impact of AI-powered chatbot interactions versus traditional educational handouts on increasing participants' knowledge of oral cancer and its prevention
- Conditions
- Oral Cancer, Chatbot, Patient Education, Prevention
- Trial name
- NCT06682494
- Testing
- Traditional Education, AI-powered Chatbox
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Medical History Taking, Artificial Intelligence in Clinical Workflow
Augmenting Clinical Workflow With a Structured Chatbot for Patient History Collection and Diagnostic Support
Doctors spend much of each visit collecting the patient's medical history, and incomplete histories can delay diagnosis. This study tests an AI chatbot that interviews patients before their appointment and produces a structured…
- Conditions
- Medical History Taking, Artificial Intelligence in Clinical Workflow, Outpatient Clinical Encounter
- Trial name
- CHAT-HX (NCT07860762)
- Testing
- AI-Based Structured History-Taking Chatbot
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Psychological Stress, Perceived Stress
A Persian AI-Based CBT Chatbot and Voice Analysis System for Managing Perceived Stress
This pilot randomized controlled trial aims to evaluate a Persian-language artificial intelligence (AI)-based cognitive behavioral therapy (CBT) chatbot designed to support adults in managing perceived stress.
- Trial name
- PersianAI-CBT (NCT07840469)
- Testing
- Persian AI-Based CBT Chatbot, Active Mental Health Content
- Where
- Iran
- Volunteers
- 120 people
- Sponsor
- Hamid Reza Marateb
Healthy
Chatbot Intervention Effects on Emotional Arousal in Anhedonia
The main aim of the present study is to investigate the effects of a Motivational Interviewing-based artificial intelligence chatbot on affective arousal in college students with elevated levels of depression and anhedonia by…
- Trial name
- NCT07671131
- Testing
- MI Chatbot Interaction, Active Control Chatbot Interaction
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China