Clinical trials: Abdomen Disease
Non-Alcoholic Fatty Liver Disease, Central Obesity
12-Month Once-a-week HIIT Improves Body Adiposity and Liver Fat
Obesity and non-alcoholic fatty liver disease (NAFLD) are two related growing epidemics that are becoming pressing public health concerns.
- Trial name
- NCT03912272
- Testing
- High-intensity Interval Training, Usual Care Control
- Where
- Hong Kong
- Volunteers
- 160 people
- Sponsor
- The University of Hong Kong
Appendicitis
Restricted or Liberal Antibiotics After Appendectomy - Denver Health
The purpose of this study is to see if decreasing the amount of antibiotics after appendicitis surgery can decrease the risk of adverse effects associated with antibiotics while at the same time ensuring participant safety.
- Trial name
- CASARELAX (NCT05002829)
- Testing
- Restricted Duration of SOC Antibiotic Use, Liberal Duration of SOC Antibiotic Use
- Where
- United States
- Volunteers
- 657 people
- Sponsor
- Denver Health and Hospital Authority
Breast Cancer
TAP vs QL for Postoperative Analgesia After DIEP Free Flap Breast Reconstruction
The purpose of this study is to compare the efficacy of Transversus abdominus plane (TAP) block and Quadratus Lumborum (QL) block on the quality of recovery after breast reconstruction with deep inferior epigastric perforator…
- Trial name
- NCT05301595
- Testing
- TAP block, QL Block
- Where
- Canada
- Sponsor
- Ottawa Hospital Research Institute
Appendicitis Acute, Appendicitis
Safety & Feasibility of PERIsign System in Demonstrating Involuntary Muscle Defense as a Sign of Peritonitis in Subjects With Appendicitis
This will be an explorative, proof-of-principle, open, multi-center investigation. The investigation aims to investigate the safety of the PERIsign system and the ability of physicians to differentiate between healthy individuals…
- Conditions
- Appendicitis Acute, Appendicitis, Abdominal Pain, Peritonitis
- Trial name
- PeriSaFe01 (NCT06296953)
- Testing
- PERIsign examination
- Where
- 2 sites in Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- STB INN AB
Laparoscopic Abdominal Surgery
Pre-operative Carbohydrate Drink to Preserve Peri-operative Insulin Sensitivity
Enhanced Recovery after Surgery (ERAS) pathways include multiple evidence-based interventions delivered throughout the peri-operative period that aim to attenuate the surgical stress response and support rapid physiologic and…
- Trial name
- NCT02673502
- Testing
- simple carbohydrate drink, complex carbohydrate drink
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Transcutaneous Electrical Acupoint Stimulation, Postoperative Sleep Disturbances
TEAS on Sleep Quality and POCD in Elderly Patients
Elderly patients are often considered as a high-risk population for major abdominal surgery due to reduced functional reserve and increased comorbidities.
- Conditions
- Transcutaneous Electrical Acupoint Stimulation, Postoperative Sleep Disturbances, Postoperative Cognitive Dysfunction, Elderly Patients
- Trial name
- NCT04850196
- Testing
- TEAS, control group
- Volunteers
- 100 people
- Sponsor
- Shengjing Hospital
Thoracoabdominal Aortic Aneurysm
Thoracoabdominal Aortic Aneurysms
Evaluation of the effectiveness of the different modalities for treatment of thoracoabdominal aortic aneurysms. FEVAR and BEVAR devices are widely used now due to its feasability and wide range of use .
- Trial name
- NCT06267573
- Testing
- Fenestrated and branched endovascular devices for TAAA
- Volunteers
- 100 people
- Sponsor
- Assiut University
Gastric Foreign Body, Nos, Disorder of Abdomen (Disorder)
Transluminal Flexible Endoscopic Procedure in Foregut and Urologic Surgery
NOTES access is safe and feasible in the controlled human setting and comparable to standard-of-care surgical techniques. NOTES exploration of the abdomen provides adequate visualization comparable to laparoscopy.
- Conditions
- Gastric Foreign Body, Nos, Disorder of Abdomen (Disorder), Foreign Body in Esophagus, Prostatic Diseases
- Trial name
- NOTES (NCT00484783)
- Testing
- Natural Orifice Transluminal Endoscopic Surgery (NOTES), Natural Orifice Translumenal Endoscopic Surgery (NOTES)
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University Hospitals Cleveland Medical Center
Umbilical Hernia, Ventral Hernia
Duramesh Versus Minimally Invasive IPOM for High-Risk Umbilical Hernia Repairs
Umbilical hernias are common, and repair with mesh lowers the risk of the hernia coming back compared with stitches alone. Most evidence comes from lower-risk patients.
- Trial name
- NCT07881354
- Testing
- Duramesh, Mesh
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Northwestern University
Postoperative Delirium (POD), Abdominal Neoplasms
Perioperative Biomarkers and Postoperative Delirium in Older Adults Undergoing Abdominal Cancer Surgery
This prospective observational cohort study aims to investigate the relationship between perioperative endogenous melatonin levels and postoperative delirium in patients aged 65 years or older undergoing elective abdominal cancer…
- Trial name
- NCT07859488
- Testing
- Perioperative Biomarker Assessment, Confusion Assessment Method (CAM)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Fatma Cigdem Ozakin
Aortic Aneurysm, Abdominal
Enhanced Guidance for Endovascular Repair of Abdominal Aortic Aneurysm
An increasing incidence of abdominal aortic aneurysms (AAA) is observed in our ageing population. Since it is less invasive, endovascular repair (EVAR) by stent-graft (SG) insertion is frequently indicated in patients with…
- Trial name
- AAA 2D/3D II (NCT01824654)
- Testing
- Validation of the new rigid registration software, Validation of the new elastic registration software
- Where
- 2 sites in Canada
- Volunteers
- 25 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Delirium, AAA
Abdominal Aortic Aneurysm Patients Remain at Risk for Delirium on the Surgical Ward After Intensive Care Unit Dismissal
The incidence of delirium following open abdominal aortic aneurysm (AAA) surgery is significant, with incidence rates ranging from 12 to 33%.
- Conditions
- Delirium, AAA, Intensive Care Unit Delirium, Surgery--Complications
- Trial name
- NCT04080557
- Testing
- Surgery
- Where
- Netherlands
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Amphia Hospital
Weight Loss, Abdominal Obesity
Highest Weight Loss and Abdominal Adiposity Loss With Hypocaloric Diet Plan and Auricular Acupuncture
The implications of obesity, especially visceral fat, in health are well known. It would be desirable to control obesity by safe and effective treatment modalities.
- Trial name
- NCT04834180
- Testing
- Hypocaloric diet plan, Auricular Acupuncture, Acupressure
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Andreia Vieira
Hemodynamic Response, Acute Appendicitis
Lidocaine VS Hemodynamic, Metabolic and Hormonal Response
Intravenous lidocaine - a potent local anesthetic with analgesic and anti- inflammatory properties has been shown to be an effective adjunct that reduces intra and postoperative opioid consumption and facilitates pain management…
- Conditions
- Hemodynamic Response, Acute Appendicitis, Complication of Treatment, Opioid Consumption
- Trial name
- NCT05238506
- Testing
- Intravenous lidocaine, Normal saline infusion
- Where
- Poland
- Volunteers
- 132 people
- Sponsor
- Medical University of Warsaw
Aneurysm
Non-Invasive Treatment of Abdominal Aortic Aneurysm Clinical Trial
The primary aim of this study is to determine if doxycycline (100 mg bid) will inhibit (by at least 40%) the increase in greatest transverse diameter of small abdominal aortic aneurysms (3.5-5.0 cm in men, 3.5-4.5 cm in women)…
- Trial name
- N-TA^3CT (NCT01756833)
- Testing
- Doxycycline
- Where
- 22 sites in United States
- Volunteers
- 261 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Cryptorchidism
Shehata Technique in the Treatment of Intra-abdominal Testis
This study focuses on children diagnosed with intra-abdominal cryptorchidism, a condition in which the testicle remains lodged in the abdomen instead of descending to the scrotum.
- Trial name
- INP2024/063 (NCT06862258)
- Testing
- Shehata technique
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- National Institute of Pediatrics, Mexico
Obesity, Obesity, Abdominal
Laparoscopic Clip-Gastroplasty With The Use Of Bariclip
Sleeve gastrectomy, the most commonly performed bariatric surgery procedure, carries limitations both short-term including postoperative complications such as hemorrhage and gastric fistula and long-term such as weight regain and…
- Conditions
- Obesity, Obesity, Abdominal, Surgery
- Trial name
- B-Clamp (NCT05557084)
- Testing
- laparoscopic vertical clip gastroplasty (LVCG) with Bariclip.
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- University of Rome Tor Vergata
Thoracoabdominal Aneurysm, Abdominal Aortic Aneurysm
Endovascular Exclusion of TAAA/AAA Utilizing Fenestrated/Branched Stent Grafts
The purpose of the study is to evaluate the role of fenestrated/branched stent-grafts in the exclusion of abdominal aortic and thoracoabdominal aneurysms.
- Trial name
- NCT00583050
- Testing
- Endovascular Aneurysm Repair
- Where
- United States
- Volunteers
- 1,366 people
- Sponsor
- The Cleveland Clinic
Peritoneal Infection
Pharmacokinetics Study of Intraperitoneal Administration of Daptomycin in Peritoneal Infection
Peritoneal infection is still a frequent complication in peritoneal dialysis patients . In France, It contributes to the technique failure, responsible for about 20% of cases of transfer in hemodialysis.
- Trial name
- DAPTODP (NCT02000414)
- Testing
- intraperitoneal daptomycin
- Where
- France
- Volunteers
- 8 people
- Sponsor
- University Hospital, Caen
Acute Appendicitis
Comparative Study on the Diagnostic Validity of the Alvarado Score, Appendicitis Inflammatory Response (AIR), and Adult Appendicitis Score (AAS) in Acute Appendicitis at East Lancashire Hospitals NHS Trust (ELHT)
This retrospective observational study aims to compare the diagnostic accuracy of Alvarado Score, Appendicitis Inflammatory Response (AIR) Score, and Adult Appendicitis Score (AAS) in predicting histologically confirmed acute…
- Trial name
- DV-AAA ELHT (NCT07804238)
- Where
- United Kingdom
- Volunteers
- 300 people
- Sponsor
- East Lancashire Hospitals NHS Trust
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