Clinical trials: Abdomen Disease
Acute Kidney Injury
Acute Kidney Injury - Biomarkers in Major Abdominal Surgery
To validate Urinary Biomarkers for the prediction of AKI in major abdominal surgery patients
- Trial name
- AKI-BioMAS (NCT04582747)
- Testing
- Urinary Biomarkers (NGAL, DKK-3, IGFBP-7/TIMP-2, KIM-1)
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust
Aortic Aneurysm, Aortic Aneurysm, Abdominal
Safety and Efficacy of Multiple Overlapping Uncovered Stents for Pararenal Aortic Aneurysm Repair
Complex aortic aneurysms involving major branches have been difficult endovascularly. The primary purposes of this study is to evaluate the safety, feasibility, and efficacy of multiple overlapping uncovered stents in treating…
- Conditions
- Aortic Aneurysm, Aortic Aneurysm, Abdominal, Aortic Aneurysm, Thoracic, Aortic Aneurysm, Thoracoabdominal
- Trial name
- SEMPER (NCT01985906)
- Testing
- Multiple overlapping uncovered stents, Uncovered stents
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Changhai Hospital
Abdominal Pain, Inflammatory Bowel Diseases
Understanding Abdominal Pain in IBD and IBS
Abdominal pain is a central symptom of Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS). IBD is an autoimmune disease characterized by inflammation of the gastrointestinal tract.
- Conditions
- Abdominal Pain, Inflammatory Bowel Diseases, Irritable Bowel Syndrome
- Trial name
- NCT04020835
- Where
- 3 sites in United Kingdom
- Volunteers
- 90 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Abdominal Aortic Aneurysm
Post-Approval Study of the TREO Abdominal Stent-Graft System
The purpose of this study is to determine the long-term performance of the TREO Abdominal Stent-Graft as a treatment for patients with Infrarenal Abdominal Aortic Aneurysms or Aorto-iliac Aneurysms.
- Trial name
- TREO PAS (NCT04697784)
- Testing
- TREO Abdominal Stent-Graft System
- Where
- 40 sites in United States
- Volunteers
- 338 people
- Sponsor
- Bolton Medical
Inguinal Hernia, Premature Birth of Newborn
Timing of Inguinal Hernia Repair in Premature Infants
The purpose of this study is to determine whether early (before NICU discharge) or late (55-60 weeks post-menstrual age) inguinal hernia repair is safer for premature infants who have an inguinal hernia.
- Trial name
- NCT01678638
- Testing
- IH repair before NICU discharge, IH repair at 55-60 weeks post-menstrual age
- Where
- 40 sites in United States
- Volunteers
- 338 people
- Sponsor
- Vanderbilt University Medical Center
Obesity, Visceral, Obesity; Endocrine
Study of Lipolysis of Visceral Reserve Fat Using Tecar Therapy.
The Scope of this study is to assess the visceral and subcutaneous fat loss in patients having Tecar (Radiofrequency) Therapy and its effects on other anthropometric variables, adipokines and inflammation.
- Trial name
- NCT06377358
- Testing
- Tecar Therapy
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- CAPENERGY MEDICAL, SL
Inguinal Hernia, Acute Appendicitis
The Onset Time of Rocuronium in Emergency and Elective Surgery
Rocuronium, a nondepolarizing neuromuscular blocking agent, is used in general anesthesia to provide conditions for endotracheal intubating.
- Trial name
- NCT02634255
- Testing
- Rocuronium elective surgery, Rocuronium emergency surgery, Propofol
- Volunteers
- 50 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Nerve Compression Syndrome, Abdominal Pain
Visualizing ACNES and LUCNES With DIRT
Anterior cutaneous nerve entrapment syndrome (ACNES) is caused by nerve entrapment in the abdominal wall. Recently de Weerd and Weum have suggested lumbar cutaneous nerve entrapment syndrome (LUCNES) as a name for a similar…
- Conditions
- Nerve Compression Syndrome, Abdominal Pain, Lower Back Pain
- Trial name
- NCT05080452
- Testing
- Dynamic infrared thermography (DIRT)
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- University Hospital of North Norway
Functional Abdominal Pain Disorders
Internet-Delivered CBT for Children With Functional Abdominal Pain Disorders
This randomized controlled study aims to evaluate the efficacy of exposure-based Internet-delivered cognitive behavior therapy for children 8-12 years with Functional Abdominal Pain Disorders.
- Trial name
- NCT02873078
- Testing
- Internet-delivered Cognitive behavior therapy
- Where
- Sweden
- Volunteers
- 91 people
- Sponsor
- Karolinska Institutet
Pancreas Cancer, Pancreatic Fistula
Validations of New cut-of for the Stratification of Postoperative Complications,Drains Management
Pancreatic fistula (PF) represents the Achille's heel of pancreatic surgery and is the main cause of postoperative morbidity since it can determine the onset of others complications such as abdominal abscesses, surgical wound…
- Trial name
- DALCUT (NCT04380506)
- Testing
- Surgical Drains Management
- Where
- Italy
- Volunteers
- 165 people
- Sponsor
- Campus Bio-Medico University
Malignant Neoplasm of Large Intestine TNM Staging Primary Tumor (T) T4, Peritoneal Carcinomatosis
Surgery With HIPEC in Treating Patients With a High Risk of Developing Colorectal Peritoneal Carcinomatosis
Multicentric randomised trial. The goal of this clinical research study is to learn if hyperthermic intraperitoneal chemotherapy (HIPEC) will help to decrease the rate of peritoneal carcinomatosis(PC) in patients with high risk…
- Trial name
- NCT02179489
- Testing
- Surgery and Hyperthermic Intraperitoneal Chemotherapy with MMC
- Where
- 9 sites in China
- Volunteers
- 271 people
- Sponsor
- Zhejiang University
Liver Disease Parenchymal
Bloody or Well Done. How Would You Like Your Liver Biopsy, Sir?
This is a randomized comparative trial between percutaneous liver biopsy and EUS FNB guided liver biopsy in patients with parenchymal liver disease.
- Trial name
- LIMPID (NCT06231082)
- Testing
- Group one - percutaneous (P), Group two - EUS FNB (E)
- Where
- Romania
- Volunteers
- 78 people
- Sponsor
- Carol Davila University of Medicine and Pharmacy
Surgery, Cardiac Output, Low
Reliability of a New Pulse Contour Technique for Diagnosing an Increase in Stroke Volume During a Fluid Challenge for Hemodynamic Optimization in Patients Scheduled for High-risk Abdominal Surgery: Comparison With Transthoracic Echocardiography: COMPARE Study
The present study aims at assessing the ability of a new pulse contour device for diagnosing a >15% stroke volume (SV) increase during patient hemodynamic optimization by fluid challenge in high risk abdominal surgery.
- Trial name
- COMPARE (NCT04871620)
- Testing
- >15% SV increase during fluid challenge
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Perforated Appendicitis
Prospective Randomized Evaluation of Antibiotic Regimen Following Appendectomy for Perforated Appendicitis
The purpose of this study is to compare traditional triple antibiotic therapy against dual single day dosing antibiotic therapy in the management of perforated appendicitis in children.
- Trial name
- NCT00195923
- Testing
- Ampicillin, gentamicin, clindamycin, flagyl, ceftazidime
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Children's Mercy Hospital Kansas City
Gastric Cancer, Gastric Adenocarcinoma
Near-infrared Imaging With Indocyanine Green for Detection of Peritoneal Metastases for Gastric Adenocarcinoma.
Peritoneal disease at initial presentation for patients with gastric adenocarcinoma (GA) is frequent, with 15-31% of patients presenting with peritoneal metastases (PM) at surgical exploration.
- Conditions
- Gastric Cancer, Gastric Adenocarcinoma, Peritoneal Carcinomatosis, Peritoneal Metastases
- Trial name
- NCT05687617
- Testing
- Indocyanine green
- Where
- 2 sites in Canada
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Laval University
Appendicitis
Pediatric Appendicitis Pathway Study
The purpose of this study is to test a standardized approach for children being evaluated for appendicitis in the emergency department.
- Trial name
- NCT01192620
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Oregon Health and Science University
Diabetes, Chronic Kidney Diseases
Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY)
This research programme seeks to combine the resources of NHS primary care, with the leading spectroscopic work in low-magnetic fields of the Wilson Group (Nottingham Trent University) to demonstrate the potential for benchtop…
- Conditions
- Diabetes, Chronic Kidney Diseases, Cancer, Bowel Disease
- Trial name
- BRANCH-P (NCT05473325)
- Where
- United Kingdom
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Willows Health
Thoraco-abdominal Aneurysm, Aortic Dissection
Outcomes of Secondary Endovascular Aortic Repair After Initial Frozen Elephant Trunk Procedure
Objective Complex aortic pathology has been revolutionized with the use of hybrid prostheses such as the Thoraflex® Hybrid Frozen Elephant Trunk (FET).
- Trial name
- NCT05571930
- Testing
- Secondary TEVAR after initial FET procedure
- Volunteers
- 30 people
- Sponsor
- University Paul Sabatier of Toulouse
Vagus Nerve Stimulation, Obesity
Auricular Vagus Stimulation in Obesity
Transcutaneous vagus nerve stimulation (TENS) involves stimulation of the left and/or right auricular branch of the vagus nerve with low-frequency electrical impulses.
- Trial name
- NCT05230628
- Testing
- Active TENS
- Where
- Russia
- Volunteers
- 131 people
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Aortic Aneurysm, Abdominal
The Effect of Doxycycline on Matrix Metalloproteinase Expression and Activity in the Abdominal Aneurysm
The matrix metalloproteinase-9 (MMP-9) is considered to play a central role in abdominal aortic aneurysm (AAA) initiation. Doxycycline has direct MMP-9 inhibiting properties in vitro, and it effectively suppresses AAA development…
- Trial name
- NCT00538967
- Testing
- doxycycline
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Leiden University Medical Center
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