Clinical trials: Abdomen Disease
Aortic Aneurysm, Abdominal, Arterial Occlusive Diseases
Plasma Transfusion in Major Vascular Surgery
BACKGROUND Major blood loss is frequent in open repair of ruptured and intact abdominal aortic aneurysm (AAA) as well as in aorto-bifurcated prosthesis insertion due to aortoiliac occlusive disease.
- Trial name
- NCT04514575
- Testing
- Plasma transfusion
- Where
- Denmark
- Volunteers
- 17,000 people
- Sponsor
- Naestved Hospital
Carcinomatosis, Peritoneal
Inferior Epigastric Lymp Node (IELN) Basin as a Possible Systemic Metastatic Pathway of Ovarian Peritoneal Metastases
The IELN basin could represent a primary LN relay for systemic metastatic dissemination in patients with OPM. This newly described lymphatic pathway of metastatic dissemination of OPM may be involved in certain presentations of…
- Trial name
- OvEpiLyPath (NCT06237582)
- Testing
- epigastric lymph node biopsy
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Jules Bordet Institute
Pneumonia, Abdominal Infection
Target Site Pharmacokinetics of Doripenem at Steady State in Intubated Intensive Care Patients
The investigators will measure the pharmacokinetics of doripenem in skeletal muscle, subcutaneous adipose tissue, bronchoalveolar lavage and plasma of intubated intensive care patients.
- Conditions
- Pneumonia, Abdominal Infection, Urinary Tract Infection
- Trial name
- NCT01414959
- Where
- Austria
- Volunteers
- 16 people
- Sponsor
- Medical University of Vienna
Gallstone
Post-Cholecystectomy Quality of Life
The study aims to identify factors associated with no increase in gastrointestinal quality of life after elective cholecystectomy for gallstones.
- Trial name
- NCT03326154
- Testing
- No intervention, observational
- Where
- 2 sites in Finland
- Volunteers
- 1,000 people
- Sponsor
- Helsinki University Central Hospital
Atherogenic Dyslipidaemia, Abdominal Obesity
Pilot Study With GFT505 (80mg) in Atherogenic Dyslipidaemic Patients With Abdominal Obesity
The purpose of this study is to evaluate the efficacy of GFT505 80mg in reducing serum Triglycerides (TG) and increasing High Density Lipoprotein Cholesterol (HDL-C) levels compared with placebo in atherogenic dyslipidaemic…
- Trial name
- NCT01271751
- Testing
- GFT505 80mg
- Where
- 47 sites in France, Romania and 1 more
- Volunteers
- 96 people
- Sponsor
- Genfit
Coagulopathy in Patients Having Thoraco-Abdominal Aneurysm Repair
Fibrinogen as an Alternative to FFP in Aortic Surgery.
Thoracoabdominal aneurysm (TAAA) repair is a major elective vascular operation associated with a large blood loss and potentially life-threatening clotting abnormalities.
- Trial name
- NCT00994045
- Testing
- Fibrinogen concentrate, Fresh Frozen Plasma
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Edinburgh
Abdominal Compartment Syndrome
This Study Performed to Develop a New Technique for Measuring the Intra Abdominal Pressure
The purpose of this study is to evaluate the changes of intraocular pressure due to the increase of intra abdominal pressure.
- Trial name
- NCT02319213
- Testing
- Intraocular pressure measurement with 9 mmHg insufflation, Intraocular pressure measurement with 12 mmHg insufflation, Intraocular pressure measurement with 15 mmHg insufflation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Acute, Perforated Appendicitis
Dilute Povidone-iodine Irrigation vs No Irrigation for Children With Acute, Perforated Appendicitis
The goal of this study is to compare the efficacy of PVI irrigation to no irrigation for decreasing postoperative intra-abdominal abscesses in children with perforated appendicitis.
- Trial name
- NCT02664220
- Testing
- Povidone-iodine irrigation, No irrigation
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The University of Texas Health Science Center, Houston
Necrotising Enterocolitis
Imaging Modalities in Diagnosing Necrotizing Enterocolitis in Preterm Infants.
Background Necrotizing enterocolitis (NEC) is one of the most serious conditions in newborns, affecting up to 10% of very low birth weight infants (VLBW). In the most premature population mortality rates can rise as high as 60%.
- Trial name
- NCT03188380
- Testing
- Plain abdominal radiography, Abdominal ultrasound
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Princess Anna Mazowiecka Hospital, Warsaw, Poland
Abdominal Disorder
Evaluation of Laparoscopic Cholecystectomy and Concomitant Paraumbilical Hernia Repair
Umbilical hernia frequently accompanies cholelithiasis. It is possible to repair these hernias after completing cholecystectomy.
- Trial name
- NCT06317779
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Ventral Hernia, Surgery
STRONG for Surgery & Strong for Life - Intensive Prehabilitation for Risk Reduction in Ventral Hernia Repair
The five risky lifestyles Smoking, Nutrition (obesity and malnutrition), risky Alcohol intake, and Physical inactivity (SNAP) are common in surgical patients and associated with worse postoperative outcomes.
- Conditions
- Ventral Hernia, Surgery, Risk Reduction, Lifestyle
- Trial name
- STRONG-Hernia (NCT06611462)
- Testing
- Prehabilitation (the STRONG programme)
- Where
- 3 sites in Denmark
- Volunteers
- 400 people
- Sponsor
- Bispebjerg Hospital
Abdominal Aortic Aneurysm (AAA)
Assessment of the GORE® EXCLUDER® Conformable AAA Endoprosthesis In the Treatment of Abdominal Aortic Aneurysms
EVAR continues to evolve as a treatment option for AAA. New devices which are specifically designed to perform adequately across the spectrum of potential anatomic presentations for infrarenal EVAR are needed.
- Trial name
- EXCeL (NCT03743142)
- Testing
- endovascular repair of the AAA
- Where
- 8 sites in France, Italy and 3 more
- Volunteers
- 156 people
- Sponsor
- Marc van Sambeek
Muscle Weakness
Functional Change With MMS
Evaluate the safety and efficacy of magnetic muscle stimulation (MMS) of abdominal muscle.
- Trial name
- FMS (NCT04506502)
- Testing
- The ZELTIQ System
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Functional Abdominal Pain Syndrome
Digital Psychological Intervention for Pediatric Functional Abdominal Pain Disorders in Primary Care
The project involves researching two psychological treatments for functional abdominal pain in children. The treatments will be offered to children as an early intervention, at primary care level.
- Trial name
- FAPD (NCT06481072)
- Testing
- Digital patient education, Digital patient education and iCBT
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Body Fat Disorder
Extended Follow-Up Study for Subjects Who Participated in 2010 Study
This study is being performed to follow up on subjects who participated in the initial study (ZA10-001) in 2010.
- Trial name
- JUNO (NCT01579487)
- Testing
- The Zeltiq System
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Anomaly Heart, Turner Syndrome
Role of Cardiac AngioMR in Diagnosis of Cardiac and Vascular Anomalies in Adult Patients with Turner Syndrome
Considering the high prevalence of cardiovascular disease in Turner syndrome patients, noninvasive cardiac imaging is crucial for diagnosis and follow-up.
- Trial name
- NCT06178887
- Testing
- imaging
- Where
- Italy
- Volunteers
- 33 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Diet, Healthy, Obesity, Visceral
NUTritional Impact of a Hypocaloric Hyperprotein Diet Before Obesity Surgery
Obesity is a major public health problem and is constantly on the rise. Therapeutic approaches based on dietary advice, physical activity and the management of psychological difficulties are not always sufficient to achieve a…
- Conditions
- Diet, Healthy, Obesity, Visceral, Bariatric Surgery Candidate
- Trial name
- NUTRACOB (NCT04942093)
- Testing
- With low-calorie, high-protein diet, Without low-calorie, high-protein diet
- Where
- 3 sites in France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Rouen
Peritoneal Carcinomatosis, Colon Cancer
Metachonous Peritoneal Carcinomatosis Incidence After Curative Surgery for pT4 Colon Cancer Patients
This is an observational retrospective cohort study to determine metachronous peritoneal carcinomatosis in a specific subgroup of colon cancer patients, those with a final pathologic exam corresponding to pT4 tumors.
- Trial name
- NCT05300789
- Testing
- Follow-up
- Where
- Spain
- Volunteers
- 1,152 people
- Sponsor
- Carlos Cerdán Santacruz
Ventral Hernia, Umbilical Hernia
Preperitoneal Umbilical Mesh Area
The aim of this study is to measure the mesh shrinkage and the visualization of the mesh with MRI scan at 1 month and 13 months after robot assisted preperitoneal hernia repair using the visible CICAT mesh (Dynamesh®).
- Conditions
- Ventral Hernia, Umbilical Hernia, Ventral Incisional Hernia
- Trial name
- PUMA (NCT05576753)
- Testing
- Hernia repair
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Functional Gastrointestinal Disorders, Irritable Bowel Syndrome
Does Improving Vagal Tone Increase Mitochondrial Bioenergetics
This study evaluates the effect of auricular neurostimulation on mitochondrial bioenergetics and inflammation through vagal nerve modulation via non-invasive percutaneous electrical nerve field stimulator in children with…
- Conditions
- Functional Gastrointestinal Disorders, Irritable Bowel Syndrome, Dyspepsia, Functional Abdominal Pain Syndrome
- Trial name
- NCT03931330
- Testing
- Percutaneous neurostimulation
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Medical College of Wisconsin
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