Clinical trials: Abdominal Diseases
Diabete Type 2, Abdominal Obesity
Translational Study Using Human Abdominal Adipose Tissue Biopsies to Investigate the Role of Cannabinoid Receptor 1 (CB1) in Controlling Endocannabinoid and Adipokine Secretion
Abdominal obesity and type 2 diabetes are associated with the hyperactivation of the endocannabinoid system. Several animal and human studies indicate that circulating endocannabinoid (EC) levels are correlated with body fat.
- Trial name
- ENDOCATA (NCT04940962)
- Testing
- Sampling of adipose tissue
- Where
- France
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Bone Aging, Osteoporosis Diagnosis
Automated Bone Age Estimation From Noncontrast Abdominal CT Using Deep Learning
This study is a retrospective analysis that uses abdominal CT scans, which were originally taken for other medical reasons, to estimate bone age.
- Trial name
- NCT07162168
- Where
- China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Radiomics, Multi-omics
Neurophenotype Predicts CD Disease Progression
The goal of this observational study is aimed to develop a novel multimodal neuroimaging-based model to characterize the neurophenotype of Crohn's Disease patients and assess its ability for predicting disease progression, using…
- Trial name
- NCT06452550
- Testing
- Logistic regression (LR) prediction models
- Where
- China
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Body Weight, Obesity
Meta-analysis of the Nordic Dietary Pattern on Cardiometabolic Risk and Cardiovascular Outcomes
The Nordic Diet is a dietary pattern rich in traditional Nordic foods, including berries, grains, and fatty fish common in northern Europe.
- Conditions
- Body Weight, Obesity, Overweight and Obesity, Obesity, Abdominal
- Trial name
- NCT04094194
- Testing
- Nordic diet
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity, Abdominal
Role of the Renin Angiotensin Aldosterone System in the Mechanisms of Transition to Heart Failure in Abdominal Obesity
R2C2 study has shown that abdominal obesity is associated with a cardiac and vascular remodelling in healthy volunteers. This remodelling is correlated with renin-angiotensin aldosterone system (RAAS) activation and/or systemic…
- Trial name
- R2C2-II (NCT01716819)
- Testing
- Urine sample, Blood sample, Assessment of sleep apnea syndrome
- Where
- France
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Obesity
Study of Efficacy of a Probiotic and Postbiotic in Overweight and Obese Individuals
The study's main objective is to investigate the effect of a probiotic (live bacteria), postbiotic (heat-treated bacteria) on obesity parameters.
- Trial name
- Obelix (NCT05440630)
- Testing
- Probiotics, Postbiotic
- Where
- Mexico
- Volunteers
- healthy volunteers welcome
- Sponsor
- The Archer-Daniels-Midland Company
Aortic Aneurysm, Abdominal
Predicting Rupture of AAA by Anatomic and Hemodynamic Markers
The purpose of the study is to investigate imaging findings, which can help us to predict factors contributing to abdominal aortic aneurysm growth and rupture.
- Trial name
- NCT02463760
- Testing
- Medical imaging
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Hernia, Inguinal, Hydrocele
The Addition of Clonidine to 0.2% Ropivacaine for Wound Instillation After Minor Lower Abdominal Surgery in Children
The current study will compare the effects on postoperative pain relief of "freezing" (ropivacaine 0.2 %) alone and in combination with clonidine for a nerve block in children undergoing hernia repair.
- Trial name
- NCT00130091
- Testing
- clonidine
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Eastern Ontario
Central Obesity
Soy as an Innovative Dietary Component in Abdominal Obesity Management Amongst Peri- and Early Menopausal Women
This is a pilot study examining the effect of dietary supplements that contain soy products. The purpose of this study to find out if soy supplementation can help to reduce the storage of a certain kind of fat on the body…
- Trial name
- NCT02375113
- Testing
- soy supplementation
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- The University of Texas at San Antonio
Abdominal Aortic Aneurysm, Endovascular Procedures
Standardization of Physician-Modified Stent Grafts for Abdominal Aortic Aneurysms
This study explores the use of physician-modified stent grafts (PMSGs) for treating abdominal aortic aneurysms that are unsuitable for open surgery or standard endovascular grafts.
- Conditions
- Abdominal Aortic Aneurysm, Endovascular Procedures, Stents, Vascular Surgical Procedures
- Trial name
- RESTORE (NCT06585215)
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Abdominal Aortic Aneurysm Without Rupture
ShorT Stay Aneurysm Repair Study
A prospective observational cohort study to assess the eligibility, uptake, viability, acceptability, safety, and cost of a ShorT stay (23-hour) Aneurysm Repair (STAR) pathway. Outcomes will be collected for up to 1 year.
- Trial name
- STAR (NCT05279274)
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Body Fat Disorder
CoolSculpting and EMS for the Abdomen
Evaluate the use of Electromagnetic Muscle Stimulation as an adjunctive treatment to CoolSculpting.
- Trial name
- ECA (NCT03738891)
- Testing
- Zeltiq CoolSculpting System alone, Electromagnetic Muscle Stimulation alone, EMS followed by CoolSculping
- Where
- 4 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zeltiq Aesthetics
Abdominal Obesity
Effects of Weight Reduction on Sleep and Alertness in Long-distance Truck and Bus Drivers
The study is a year-long health-behaviour intervention in obese, male truck-drivers to lose weight moderately by 10%, using monthly individual counseling.
- Trial name
- SF-Truck (NCT00893646)
- Testing
- weight loss counseling
- Where
- 3 sites in Finland
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- UKK Institute
Abdominal Aortic Aneurysm, Aortic Disease
Surviving Aneurysm Surgery: A Pilot Study on Exercise Training in Abdominal Aortic Aneurysm Patients
An abdominal aortic aneurysm (AAA) is an enlargement or ballooning of the main artery supplying high pressure blood from the heart to the body.
- Conditions
- Abdominal Aortic Aneurysm, Aortic Disease, Vascular Disease, Cardiovascular Disease
- Trial name
- SAS (NCT01805973)
- Testing
- Exercise Training
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Manchester University NHS Foundation Trust
Metabolic Disease
Effect of Aerobic Exercise Associated With Abdominal Laser Therapy
The purpose of the present study was to evaluate the effects of one session of aerobic exercise associated with low level laser therapy in lipolytic activity, lipid profile and inflammatory markers (C-reactive protein - CRP).
- Trial name
- NCT03462537
- Testing
- Low level laser therapy, Aerobic Exercise, Low level laser therapy without power
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Tecnologia da Saúde do Porto
Obesity (BMI>30), Postoperative Cognitive Function
Postoperative Cognitive Function After Different Anesthetic Techniques in Obese Patients
Obese patients are at increased risk of postoperative cognitive dysfunction (POCD). The effects of different anesthetic techniques on postoperative cognitive function remain controversial.
- Trial name
- NCT07665645
- Testing
- Sevoflurane (Volatile Anesthetic), propofol, Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Gaziantep City Hospital
Ventral Hernia, Ventral Incisional Hernia
Open Preperitoneal Mesh Versus Retromuscular Mesh Versus Suture Repair for Abdominal Wall Hernias
Randomized clinical trial comparing open preperitoneal mesh, retromuscular mesh and suture repair for ventral hernias less than 3 cm diameter
- Conditions
- Ventral Hernia, Ventral Incisional Hernia, Umbilical Hernia
- Trial name
- NCT03255239
- Testing
- Ventral hernia repair
- Where
- Tunisia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hôpital Universitaire Taher Sfar
Central Obesity, Hypertriglyceridemia
Fructose Consumption and Metabolic Dysregulation
High fructose intake is increasingly recognized as causative in development of prediabetes, metabolic syndrome and cardiovascular disease (CVD).
- Trial name
- NCT01445730
- Testing
- Fructose
- Where
- 4 sites in Canada, Finland and 2 more
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Marja-Riitta Taskinen
Physical Activity, Central Obesity
Is Physical Activity, Obesity, and Ethnicity Associated With the Tethering and Migration of Pro-inflammatory Monocytes?
Being south Asian or centrally obese may be associated with an increased risk of inflammation. The investigators are seeking to investigate whether this is the case by recruiting white European and south Asian men who are lean or…
- Conditions
- Physical Activity, Central Obesity, Inflammation
- Trial name
- NCT04761081
- Testing
- Habitual physical activity assessment
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Obesity, Dyslipidemia
Effect of Abdominal Obesity on Lipoprotein Metabolism
Abdominal obesity is strongly associated with dyslipidemia, which may account for the associated increased risk of atherosclerosis and coronary disease.
- Conditions
- Obesity, Dyslipidemia, Insulin Resistance
- Trial name
- NCT00438061
- Testing
- Weight loss by dietary restriction
- Where
- Australia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Western Australia