Clinical trials: Abdominal Infection
Pain, Postoperative, Appendicitis
Choose the Best Concentration of Ropivacaine on TAP Block for Open Appendectomy in Children
Blockage of the transverse abdomen (TAP) promotes excellent analgesia of the abdominal wall and the parietal peritoneum. The TAP block could advange the postoperative pain of Appendectomy in children.
- Trial name
- NCT03005808
- Testing
- Ropivacaine
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hospital Infantil Albert Sabin
Sepsis, Cardiac Arrest
Validation of Molecular and Protein Biomarkers in Sepsis
Background: Sepsis (blood poisoning) is a clinical syndrome characterised by a dysregulated host response to infection causing life-threatening organ dysfunction which results in admission to an intensive care unit.
- Conditions
- Sepsis, Cardiac Arrest, Pneumonia, Abdominal Sepsis
- Trial name
- VAMp-sepsis (NCT04289506)
- Testing
- mRNA expression
- Where
- 3 sites in United Kingdom
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Public Health England
Healthy
Environmental Game After Appendicitis Surgery
This study was conducted to determine the effect of environmental play and mobilization on fear and pain levels of children aged 6-12 years who had acute appendicitis surgery.
- Trial name
- NCT05104021
- Testing
- game
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Okan University
Postoperative Infection, Abdominal Surgery
Study for Rapid Diagnosis of Postoperative Abdominal Infection
This is a prospective and exploratory study, which utilizes non-targeted metagenomic next-generation sequencing (mNGS) detecting drain fluid from patients who are suspected of postoperative abdominal infection.
- Conditions
- Postoperative Infection, Abdominal Surgery, Intra-abdominal Infection, Postoperative Fever
- Trial name
- NCT05187871
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Appendicitis Acute
Online Field Test of an Appendicitis Decision Support Tool
After the recent publication of the CODA Trial comparing antibiotics and surgery for acute appendicitis, the investigators developed a comprehensive decision support tool.
- Trial name
- NCT05219786
- Testing
- Appendicitis Decision Support Tool, Control Infographic
- Where
- United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University of Washington
Appendicitis Acute, Cesarean Wound Disruption With Postnatal Complication
Are Cesarean Section and Appendectomy in Pregnancy and Puerperium Interrelated?
It is not known whether appendectomy for acute appendicitis (AA) increases the Cesarean section (CS) rate and whether CS increases the likelihood of AA and appendectomy in the early puerperium.
- Trial name
- APPENDECTOMY (NCT04876547)
- Testing
- appendectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Amasya University
Mitochondrial Oxygenation Measurement, Surgical Site Infection
Anaesthetic Management Guided by COMET Measurements
Surgical site infection (SSI) is a significant cause of morbidity and mortality, prolonged hospital stays and healthcare costs. Perioperative low tissue oxygen tension is associated with a high risk of SSI.
- Trial name
- AIMED COMET (NCT05841576)
- Testing
- COMET monitoring device
- Where
- Netherlands
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Rick Hulskes
Appendicitis
Comparison of Medical and Surgical Treatment of Uncomplicated Acute Appendicitis in Children
Several prior studies have demonstrated that medical management of acute appendicitis in adults is a safe first-line therapy option.
- Trial name
- NCT02991937
- Testing
- Piperacillin/Tazobactam, Surgical Treatment
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Immunization, Human Influenza
Study of Yili Mei Yi Tian Active Lactobacillus Drink to Improve Immunity and Digestive System
Study on Evaluating the Promote Effect of Yili Mei Yi Tian Active Lactobacillus Drink on Immunity and Physical Intestinal Canal
- Conditions
- Immunization, Human Influenza, Common Cold, Constipation
- Trial name
- NCT01677715
- Testing
- Yili "Mei Yi Tian" active lactobacillus drink, recombined milk drink contains no lactobacillus
- Where
- 2 sites in China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Inner Mongolia Yili Industrial Group Co., Ltd
Surgical Wound Infection
Closed Incision Negative Pressure Wound Therapy for the Prevention of Surgical Site Infections in Abdominal Surgery
Surgical site infections (SSI) are a frequent complication in abdominal surgery. SSI lead to worse outcomes for the affected patients and significantly higher healthcare costs.
- Trial name
- CISSI (NCT06068517)
- Testing
- Closed incision negative pressure wound therapy, Standard dressing
- Where
- Switzerland
- Volunteers
- 654 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Appendicitis
A Comparison of UGBRS Block and Local Infiltration
In this research study, the investigators are trying to find out which of the two methods of injecting local anesthetics (at the site of the belly button cut or by ultrasound guided rectus sheath block) will provide better pain…
- Trial name
- NCT02352519
- Testing
- UGBRSB, Local Infiltration
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
AI (Artificial Intelligence), Mammary Cancer
Experiment on the Use of Innovative Computer Vision Technologies for Analysis of Medical Images in the Moscow Healthcare System
It is planned to integrate various services based on computer vision technologies for analysis of the certain type of x-ray study into Moscow Unified Radiological Information Service (hereinafter referred to as URIS).
- Conditions
- AI (Artificial Intelligence), Mammary Cancer, Lung Cancer, X-Rays; Lesion
- Trial name
- NCT04489992
- Where
- Russia
- Volunteers
- 133,000 people, healthy volunteers welcome
- Sponsor
- Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department
Obesity, Morbid, Obesity
CiNPT for Abdominoplasties in Post-bariatric Patients Study
The overarching goal of this research is to assess whether the post-operative use of closed-incision Negative Pressure Therapy (ciNPT) accelerates healing of surgical wounds, improves surgical outcomes, and reduces the rate of…
- Conditions
- Obesity, Morbid, Obesity, Obesity, Abdominal, Wound
- Trial name
- CAPS (NCT04214236)
- Testing
- ciNPT group, Control group
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera, Ospedale Civile di Legnano
Postoperative Pain
Effects of Perioperative Administration of Intravenous Lidocaine in Children Operated on for Acute Generalized Peritonitis
Intravenous administration of lidocaine perioperatively after laparotomy for peritonitis could be an interesting alternative by reducing the duration of postoperative ileus, the intensity of pain and the patient's hospital stay…
- Trial name
- NCT06051630
- Testing
- Lidocaine intravenous, Serum saline intravenous
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Université NAZI BONI
Appendicitis, Surgery
Closure of the Appendix Stump in Laparoscopic Appendectomy
Aimed to the study evaluate the superiority of intracorporal sutures and Hem-o-lok clips in terms of efficiency.
- Trial name
- NCT03930667
- Testing
- clips, knotting
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Orhan Üreyen
Dyspepsia Abdominal Burning Pain Diarrhea Dysentery
Concomitant Infection of Intestinal Parasites and Helicobacter Pylori
Intestinal parasitic infections such as Giardia lamblia, Entamoeba histolyica and Enterobius Vermicularis are among the most common infections worldwide.So parasitic infections are considered one of the major health problems in…
- Trial name
- NCT05360940
- Testing
- H.pylori stool antigen rapid test and stool parasitological examination
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sohag University
Metrorrhagia, Menorrhagia
Surgical Success After Laparoscopic vs Abdominal Hysterectomy
The purpose of the proposed pilot study is to investigate the effectiveness, cost, safety, and long-term impact on quality of life of laparoscopic hysterectomy (LH) in relation to abdominal hysterectomy (AH) for the treatment of…
- Conditions
- Metrorrhagia, Menorrhagia, Leiomyoma, Adenomyosis
- Trial name
- NCT01793584
- Testing
- Laparoscopic hysterectomy, Abdominal hysterectomy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Conservative Management
Risk Factors of Failure of Conservative Treatment in Acute Non Complicated Appendicitis
From this study, it can be concluded that patients who meet the following criteria are more likely to fail expectant management and thus should not be considered for the NOM of uncomplicated acute appendicitis.
- Trial name
- appendicitis (NCT06828952)
- Testing
- ceftriaxone, ceftriaxone 1 gm/12 hourly and IV metronidazole 500 mg/8 hourly
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ahmed Mohammed Hussein Sayed
Appendicitis
The Effect of Breastfeeding on the Development of Appendicitis in Adults
Appendectomy is the most common emergent operative procedure performed worldwide. In this study investigators will investigate if there is a relationship between breast feeding and appendicitis in adults.
- Trial name
- NCT02679547
- Testing
- Breastfeeding
- Where
- 5 sites in Turkey (Türkiye)
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Peritonitis
Pedicled Seromuscular Flap For Enforcement Of High Risk Intestinal Anastomoses
This is a control matched prospective study evaluating the use of seromuscular flap for high risk anastomoses.
- Trial name
- NCT01391169
- Testing
- seromuscular flap enforcement
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mansoura University