Clinical trials: Abdominal Obesity Metabolic Syndrome
Time Restricted Feeding, Obesity, Abdominal
Efficacy and Feasibility of Time-restricted Eating on Cardiometabolic Health in Adults With Overweight/Obesity
In Spain, obesity epidemic is one of the leading contributors of chronic disease and disability. Obesity is associated with higher morbidity and all-cause mortality risk especially when fat is stored in the abdominal area (i.e.…
- Conditions
- Time Restricted Feeding, Obesity, Abdominal, Cardiometabolic Syndrome
- Trial name
- EXTREME (NCT05310721)
- Testing
- Early time-restricted eating, Late time-restricted eating, Self-selected time-restricted eating
- Where
- 2 sites in Spain
- Volunteers
- 197 people
- Sponsor
- Universidad de Granada
Metabolic Syndrome, Abdominal Obesity
Copenhagen Obesity Risk Assessment Study
The aim of the present study is to assess the effect of a high intake of industrially produced trans fatty acids for 16 weeks on abdominal obesity and risk markers of type 2 diabetes and heart disease in healthy, moderately…
- Conditions
- Metabolic Syndrome, Abdominal Obesity, Heart Disease, Type 2 Diabetes
- Trial name
- COBRA (NCT00655902)
- Testing
- Trans fat (soy bean oil), Control fat (sunflower oil)
- Where
- Denmark
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Subjects With Abdominal Obesity
Grape and Pomegranate Polyphenols in Postprandial Glucose and Related Parameters
The aim of this is study is to evaluate the acute effect of grape and pomegranate polyphenols in the modulation of markers of metabolic syndrome.
- Trial name
- POME-GRAPE-1 (NCT02710461)
- Testing
- Mixture of grape pomace and pomegranate pomace
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Research Council, Spain
Postmenopause
AFTER: Altering Fat Through Estrogen and Raloxifene
The purpose of this study is to determine whether estrogens specifically promote a reduction in fat from abdominal regions during weight loss and/or prevent the accumulation of abdominal fat during weight gain.
- Trial name
- NCT00149604
- Testing
- conjugated estrogens, Raloxifene, exercise plus mild caloric restriction for weight loss
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Overweight and Obesity, Overweight or Obesity
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Obesity
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records regarding obesity.
- Conditions
- Overweight and Obesity, Overweight or Obesity, Obesity, Obesity, Morbid
- Trial name
- NCT04100616
- Testing
- No intervention
- Where
- United States
- Sponsor
- ProgenaBiome
HIV Infections
Testosterone for HIV-Positive Men With Reduced Serum Testosterone Levels and Abdominal Fat
The purpose of this study is to see if treatment with testosterone will reduce abdominal fat in HIV-positive men. Many HIV patients on antiretroviral therapy show an increase in abdominal fat.
- Trial name
- NCT00009555
- Testing
- Testosterone
- Where
- 27 sites in United States, Puerto Rico
- Volunteers
- 86 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Obesity, Visceral, Diet, Healthy
Long-term Benefits of Abdominal Fat Loss in Abdominally Obese Dyslipidemic Patients (SYNERGIE Study)
The objective of this clinical trial is to verify whether the beneficial effects of weight loss on visceral fat measured by computed tomography and metabolic risk factors for coronary heart disease are maintained once high-risk…
- Conditions
- Obesity, Visceral, Diet, Healthy, Cardiometabolic Syndrome, Lifestyle-related Condition
- Trial name
- SYNERGIE (NCT06158191)
- Testing
- Lifestyle modification program
- Volunteers
- 186 people
- Sponsor
- Laval University
Vitamin D Deficiency, Diabetes Mellitus
Vitamin D Supplementation on Metabolic Syndrome Indicators Among Older Adults, Alborz Province, Iran
General objective: To assess the effect of vitamin D supplementation on metabolic syndrome among food insecure and vitamin D deficient older adults in Karaj city, Alborz province in Iran.
- Conditions
- Vitamin D Deficiency, Diabetes Mellitus, Hypertension, Lipid Metabolism Disorders
- Trial name
- NCT03193944
- Testing
- D-vitin, soft gelatin capsule (vitamin D3,50000 IU)
- Where
- Iran
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Alborz Medical University
Visceral Obesity, Atherosclerosis
Abdominal Fat and Imaging Measurements of Heart Disease
Although it is frequently mentioned in the media that overweight and obesity have reached epidemic proportions worldwide and in this country, some Canadians are perplexed and sometimes confused about the role of obesity in…
- Conditions
- Visceral Obesity, Atherosclerosis, Metabolic Syndrome
- Trial name
- NCT01447745
- Where
- Canada
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- Laval University
Abdominal Obesity, Abdominal Obesity-Metabolic Syndrome
Metabolic Effectiveness of Extracorporeal Shockwave on Abdominal Adiposity
Egyptian Ministry of Health and Population's Preventive Sector, have named obesity as one of the top contributors to the national mortality and morbidity.
- Conditions
- Abdominal Obesity, Abdominal Obesity-Metabolic Syndrome, Abdominal Obesity in Young and Middle Aged Adults
- Trial name
- NCT07686601
- Testing
- conventional balanced, low-calorie diet 1500 k/cal for 12 weeks, aerobic training program, extracorporeal shockwave therapy
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obesity
Dietary Intervention for Visceral Adiposity
The purpose of this research study is to determine whether increased intake of dietary fiber during a 12-week, low-calorie weight loss intervention affects abdominal fat change and improves cardiovascular risk factors in…
- Trial name
- DIVA-Pilot (NCT01350518)
- Testing
- Benefiber, TrueLemon
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Polycystic Ovarian Syndrome, Obesity, Abdominal
Acupuncture in the Regulation of Dai Meridian for Polycystic Ovarian Syndrome Patients With Abdominal Obesity
The purpose of this study is to determine whether the use of electroacupuncture to dredge and regulate Dai Meridian combined with lifestyle modification are more effective than lifestyle modification only in the treatment of…
- Trial name
- NCT02785965
- Testing
- electroacupuncture, lifestyle modification
- Where
- 2 sites in China
- Volunteers
- 84 people
- Sponsor
- Dongfang Hospital Beijing University of Chinese Medicine
Metabolic Syndrome, Insulin Resistance
EFFECTS OF OLEUROPEIN ON BLOOD PARAMETERS AND INFLAMMATORY MARKERS IN ADULTS WITH METABOLIC SYNDROME
The aim of this study is to determine the effect of 6 weeks supplementation of oleuropein on individuals diagnosed with metabolic syndrome.
- Conditions
- Metabolic Syndrome, Insulin Resistance, Obesity, Abdominal, Obesity
- Trial name
- NCT06673914
- Testing
- Control Group: Diet Group, Oleuropein and Diet Group
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Atlas University
Type 2 Diabetes, Metabolic Syndrome
Clinical Study on the Effect of a Synbiotic on Body Fat Mass
In this trial the effect of a synbiotic consisting of the three different strains of Lactobacillus fermentum and acacia gum (gum arabic) on body fat mass, body weight, long-term glycemia, insulin resistance and other risk factors…
- Conditions
- Type 2 Diabetes, Metabolic Syndrome, Obesity, Abdominal, Obesity, Visceral
- Trial name
- NCT04754464
- Testing
- synbiotic, microcrystalline cellulose
- Where
- 2 sites in Austria, Germany
- Volunteers
- 120 people
- Sponsor
- Slimbiotics GmbH
Weight Loss, Metabolic Syndrome
Signos DM2 Empowerment Study (SIGNOS-CGM-EMPOWER-201-2022)
The use of continuous glucose monitoring (CGM) in earlier data has inspired behavioral changes leading to improved adherence to an exercise plan in individuals and eating habits in people with diabetes.
- Conditions
- Weight Loss, Metabolic Syndrome, Diabetes Mellitus, Type 2, Central Obesity
- Trial name
- NCT05874635
- Testing
- Continuous Glucose Monitor Device
- Where
- United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Signos Inc
Metabolic Syndrome
Effect of a Grape Seed Extract (GSE) on Insulin Resistance
In people with the metabolic syndrome, the investigators hypothesize that administration of a single 300 mg dose of a grape seed extract (GSE) will reduce insulin resistance (how well cells in the body can take up and use…
- Trial name
- NCT01889368
- Testing
- Grape Seed Extract
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of California, Davis
Polycystic Ovary Syndrome, Metabolic Diseases
Adipose Tissue and Polycystic Ovary Syndrome (PCOS)(EIFFEL)
The purpose of this study is to collect data to help understand why some women develop Polycystic Ovary Syndrome (PCOS) associated with decreased lower-body fat.
- Conditions
- Polycystic Ovary Syndrome, Metabolic Diseases, Overweight
- Trial name
- EIFFEL (NCT01745471)
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- AdventHealth Translational Research Institute
Lumbar Spinal Stenosis, Lumbar Degenerative Disease
Effect of Obesity Phenotype on Intraabdominal Pressure and Bleeding in Major Lumbar Spinal Surgery
Obesity is prevalent among patients with lumbar degenerative disease and is a known risk factor for perioperative complications in spinal surgery.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Degenerative Disease, Obesity, Intraabdominal Hypertension
- Trial name
- OBESPINE (NCT07688265)
- Testing
- Intraabdominal Pressure Measurement via Urinary Bladder Catheter, Total Intravenous Anesthesia (TIVA)
- Volunteers
- 90 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Metabolic Syndrome, Metabolic Syndrome Obesity
Impact of Medical Nutrition Therapy and Follow-Up Frequency on Metabolic Syndrome Parameters
There is no study that has investigated the effects of medical nutrition therapy and more frequent follow-up via telehealth on metabolic syndrome parameters in patients with MetS who have multiple metabolic disorders such as…
- Conditions
- Metabolic Syndrome, Metabolic Syndrome Obesity, Metabolic Syndrome Parameters
- Trial name
- NCT06813131
- Testing
- Dietary counseling, calling via telephone
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Hacettepe University
Stress, Irritable Bowel Syndrome
Evaluating and Treating Potential Research Participants With Digestive Disorders
Background: Some research studies focus on digestive disorders, such as nutritional, gastrointestinal, and liver disorders. Researchers want to examine and treat people with digestive disorders in order to learn more about these…
- Conditions
- Stress, Irritable Bowel Syndrome, Obesity, Abdominal Pain
- Trial name
- NCT01736280
- Testing
- Standard of Care
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)