Clinical trials: Abdominal Site
Rectal Cancer
Locally Advanced Rectal Cancer - Exfoliated Peritoneal Tumor Cells
During the course of tumor growth and possibly by manipulation during the surgical procedure, cells from rectal tumors may be shed into the peritoneal cavity.
- Trial name
- LARC-EX (NCT02113384)
- Testing
- Observational study.
- Where
- Norway
- Volunteers
- 231 people
- Sponsor
- Oslo University Hospital
Peritoneum Cancer, Peritoneum Neoplasm
International Registry of Patients Treated With Pressurized IntraPeritoneal Aerosol Chemotherapy (PIPAC)
Multicentric, international, web-based prospective documentation of the indications and results of Pressurized Aerosol Chemotherapy (so-called PIPAC or PITAC) for treating malignant pleural and peritoneal diseases.
- Conditions
- Peritoneum Cancer, Peritoneum Neoplasm, Pleural Cancer, Pleural Effusion
- Trial name
- PIPACRegis (NCT03210298)
- Testing
- PIPAC
- Where
- 16 sites in Argentina, Australia and 11 more
- Volunteers
- 1,000 people
- Sponsor
- Sabine Rhode
Colorectal Neoplasms
Immunotoxin in Peritoneal Carcinomatosis- ImmunoPeCa Trial
The purpose of this study is through a phase I/II clinical trial to assess the safety and toxicity of intraperitoneally administered MOC31PE immunotoxin, given on the 1.postoperative day after cytoreductive surgery (CRS) and…
- Trial name
- ImmunoPeCa (NCT02219893)
- Testing
- MOC31PE Immunotoxin
- Where
- Norway
- Volunteers
- 15 people
- Sponsor
- Oslo University Hospital
Surgical Site Infection
Study of Chlorhexidine Gluconate as a Preoperative Antisepsis
The purpose of this study is to determine which drug (chlorhexidine gluconate vs. povidone iodine) as a preoperative antisepsis in clean-contaminated abdominal surgery (liver, hepatobiliary, small or large bowel, stomach) is…
- Trial name
- CHG (NCT01495117)
- Testing
- Povidone-Iodine, Chlorhexidine gluconate
- Where
- South Korea
- Volunteers
- 534 people
- Sponsor
- Seung Duk Lee
Retroperitoneal Neoplasms
Retroperitoneal Tumor Registry
This is an observational, real-world registry study. The RETROR registry aims to establish a clinical database for patients with retroperitoneal tumors.
- Trial name
- NCT07915895
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The First Hospital of Jilin University
Upper Gastrointestinal Cancer
The Efficacy and Safety of Accufuser Omnibus® (Elastomeric Infusion Pump); Comparative Clinical Trial
Acute post-operative pain causes not only discomfort for the patient, but delays recovery by increasing the morbidity of the circulatory system, respiratory system, and immune system, so pain control is one of the important…
- Trial name
- NCT01976494
- Testing
- The domestic PCA equipment 'Accufuser Omnibus®', Imported PCA equipment 'Infusor SV®, Baxter, USA'
- Where
- South Korea
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Rectum Cancer
Reconstruction of the Pelvic Floor and Perineal Wound After Rectal ELAPE
A multicenter, cohort, randomized, controlled study is being conducted since the 1of September, 2023 whereby the immediate and long-term results of pelvic floor and perineal wound plastic surgery after extralevatory…
- Trial name
- NCT06066931
- Testing
- Plastic surgery of the pelvic floor and perineal wound with counter-displaced skin-subcutaneous fascial flaps after extralevatory abdominal-perineal extirpation of the rectum, Plastic surgery of the pelvic floor and perineal wound with local tissues, Plastic surgery of the pelvic floor and perineal wound with mesh endoprosthesis
- Volunteers
- 150 people
- Sponsor
- Kuban State Medical University
Peritoneal Carcinomatosis
Link of Interest and Training Model
The surgical device used to perform PIPAC procedure is commercialized by a single manufacturer under a monopoly regimen, and a formal training (economically supported by the manufacturer) is mandatory for surgeons who want to buy…
- Trial name
- NCT04341337
- Testing
- interview
- Where
- France
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Centre de l'arthrose, Paris
Head and Neck Cancer, Lung Cancer
Evaluation of a Cone-beam CT Scanner for Image Guided Radiotherapy
This is a feasibility study investigating the image quality of a new, high-performance cone beam CT (CBCT) used for on-couch imaging during radiotherapy treatments.
- Conditions
- Head and Neck Cancer, Lung Cancer, Breast Cancer, Abdominal Cancer
- Trial name
- CONFIGURE (NCT05524454)
- Testing
- Novel CBCT Imaging
- Where
- Netherlands
- Volunteers
- 41 people
- Sponsor
- Varian, a Siemens Healthineers Company
Peritoneal Neoplasms, Ascites
Local mEHT + TCM Versus Intraperitoneal Chemoinfusion in Treatment of Malignant Ascites: Phase II RCT
This trial studies efficacy and safety of combination of modulated electro-hyperthermia (mEHT) with Traditional Chinese Medicine (TCM) in treatment of peritoneal carcinomatosis with malignant ascites versus standard chemoinfusion…
- Conditions
- Peritoneal Neoplasms, Ascites, Yang Deficiency, Yin Deficiency
- Trial name
- OTMA-RII (NCT02638051)
- Testing
- Modulated Electro-Hyperthermia (mEHT), TCM Herbal Decoction (Shi Pi), IPCI (CDDP+5FU)
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Galenic Research Institute Ltd
Pancreatic Neoplasm, Neoplasm of Intra-abdominal Lymph Nodes
Prospective Study Comparing Methods of Obtainment of Specimen After EUS-FNA in Patients With Peri-pancreatic Mass
EUS-guided FNA has been proved to be a safe and useful method for tissue sampling of gastrointestinal track lesions and other organ lesions including mediastinal and intra-abdominal lymph nodes, pancreas and hepatobiliary tree.
- Trial name
- EUS-FNA (NCT01354795)
- Testing
- 1.EUS-FNA with or without suction, 2.Pushing the stylet or injecting air
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Samsung Medical Center
Malignant Mesothelioma
Surgery, Chemotherapy, and Radiation Therapy in Treating Patients With Peritoneal Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving the drugs directly into the tumor after surgery and combining them with radiation therapy may kill…
- Trial name
- NCT00024271
- Testing
- recombinant interferon gamma, cisplatin, doxorubicin hydrochloride
- Where
- United States
- Sponsor
- Herbert Irving Comprehensive Cancer Center
Endometriosis, Pelvic Prolapse
Suspension of the Pelvic and Abdominal Organs During Minimally Invasive Surgery
The goal of this retrospective observational study is to evaluate the efficacy, safety, and practicality of an organ suspension technique with adjustable tension suture in facilitating minimally invasive gynecologic surgeries at…
- Conditions
- Endometriosis, Pelvic Prolapse, Endometrium Cancer
- Trial name
- NCT06187558
- Testing
- Pelvic and abdominal organ suspension technique
- Where
- Italy
- Volunteers
- 330 people
- Sponsor
- University of Cagliari
Hernia, Ventral, Intestinal Fistula
RCT of Two Noncrosslinked Porcine Acellular Dermal Matrices in Ab Wall Reconstruction
The purpose of the study is to compare the clinical outcomes of two commonly used, FDA-approved biologic meshes in hernia repair and abdominal wall reconstruction (Strattice and XenMatrix).
- Conditions
- Hernia, Ventral, Intestinal Fistula, Fibromatosis, Abdominal
- Trial name
- NCT02228889
- Testing
- Abdominal wall reconstruction with Strattice, Assess pain intensity at last office visit preoperatively, Assess pain interference at last office visit preoperatively
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Jeffrey Janis
Carcinoma, Ovarian Epithelial, Ovarian Neoplasms
Oregovomab Plus Chemo in Newly Diagnosed Patients With Advanced Epithelial Ovarian Cancer Following Optimal Debulking Surgery
Study to compare the safety and efficacy of oregovomab versus placebo, administered in combination with specific cycles of a standard six-cycle chemotherapy regimen (paclitaxel and carboplatin), for the treatment of subjects with…
- Conditions
- Carcinoma, Ovarian Epithelial, Ovarian Neoplasms, Ovarian Cancer, Ovarian Serous Adenocarcinoma
- Trial name
- FLORA-5 (NCT04498117)
- Testing
- Oregovomab, Paclitaxel, Carboplatin
- Where
- 148 sites in United States, Argentina and 12 more
- Volunteers
- 615 people
- Sponsor
- CanariaBio Inc.
Incisional Hernia After Midline Laparotomy, Colorectal Cancer
A One-year Follow-up of Incisional Hernia Formation Between Device Assisted and Manual Laparotomy Closure
The study compares one-year incisional hernia formation between two cohorts of patients that underwent open surgery for colorectal diseases.
- Trial name
- NCT07766044
- Testing
- Device assisted laparotomy closure, Manual laparotomy closure
- Where
- Sweden
- Volunteers
- 218 people
- Sponsor
- Suturion AB
Ileus
Phase 2 RCT of Alvimopan vs. Placebo After CRS/HIPEC
The purpose of this study is to investigate the ability of alvimopan to reduce the time to return of bowel function in patients undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.
- Trial name
- ILEUS (NCT03352414)
- Testing
- Alvimopan
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of California, San Diego
Surgery, Colorectal Cancer
Postoperative Electrical Muscle Stimulation Two
Undesirable loss of skeletal muscle mass (atrophy) is a common feature of many diseases as well as ageing, bed rest and physical inactivity.
- Conditions
- Surgery, Colorectal Cancer, Muscle Atrophy, Cancer Gi
- Trial name
- POEMS2 (NCT06964438)
- Testing
- Neuromuscular Electrical Stimulation, Protein supplement drink
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- University of Nottingham
Peritoneal Carcinomatosis
Register Study of Patients With Peritoneal Carcinomatosis Treated With PIPAC (Pressurized Intra-peritoneal Aerosol-Chemotherapy)
The study will follow up patients with peritoneal carcinomatosis from colorectal, ovarian, gastric, pancreatic cancers and primary peritoneal tumors and undergoing a diagnostic laparoscopy / laparotomy, a PIPAC as single dose or…
- Trial name
- PIPAC_01 (NCT03100708)
- Testing
- PIPAC
- Where
- Germany
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Leipzig
Breast Cancer
Cost-Effectiveness of Abdominal-based Autogenous Tissue vs Tissue Expander-Implant Reconstruction - A Feasibility Study
It is estimated that about 25% and 40% of health care expenditures in Canada and USA respectively are wasted because of inefficiencies and not practicing evidence-based medicine.
- Trial name
- NCT02438449
- Testing
- Breast Reconstruction Surgery
- Where
- Canada
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- McMaster University