Clinical trials: Abdominal Surgeries
Morphine, Dexmedetomidine
Morphine Versus Dexmedetomidine as Adjuvants to Bupivacaine in TAP Block in Lower Abdominal Surgeries
This study aimed to ascertain the safety and efficacy of dexmedetomidine in comparison to morphine as adjuvants to bupivacaine during transversus abdominis plane (TAP) block in postoperative pain management in adult patients…
- Conditions
- Morphine, Dexmedetomidine, Adjuvants, Bupivacaine
- Trial name
- NCT07842861
- Testing
- Transversus abdominis plane block + Dexmedetomidine, Morphine
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Postoperative Complications, Multiple Organ Failure
Dalargin for Prevention of Organ Disfunction in High-Risk Abdominal Surgery
Major abdominal surgeries (e.g., gastrectomy, pancreatectomy, colectomy) carry a high risk of life-threatening postoperative complications, including multiorgan disfunction syndrome (MODS), acute kidney injur (AKI), miocardial…
- Conditions
- Postoperative Complications, Multiple Organ Failure, Abdominal Surgery
- Trial name
- Dal-PROTECT (NCT07404358)
- Testing
- Dalargin, 0.9 % NaCl
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Botkin Hospital
Open Abdomen, Incisional Hernia
Synthetic Mesh for Prevention of HernIa After opEn Abdomen cLosure stuDy
The aim of this clinical trial is to evaluate whether placement of a synthetic prophylactic onlay mesh during definitive fascial closure can reduce the incidence of incisional hernia in adult patients managed with an open abdomen…
- Conditions
- Open Abdomen, Incisional Hernia, Definitive Fascial Closure, Emergency Abdominal Surgery
- Trial name
- SHIELD (NCT07835334)
- Testing
- Definitive Fascial Closure Without Prophylactic Mesh, Prophylactic Onlay Mesh Placement
- Volunteers
- 30 people
- Sponsor
- Hospital San Juan de Dios Tenerife
Malnutrition, Nutritional Risk
Nutritional Perihabilitation in Older Veterans Undergoing Surgery
This research study will be conducted in two parts. The first part will consist of selecting appropriate screening and assessment tools for Veterans undergoing elective surgery and identifying the number of Veterans who are…
- Conditions
- Malnutrition, Nutritional Risk, Abdominal Surgery
- Trial name
- NCT03073811
- Testing
- Protein enhanced nutrition intervention, Education Control
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VA Office of Research and Development
Pancreatic Cancer, Colo-rectal Cancer
Prehabilitation in High-risk Oncologic Surgery
The goal of this clinical study is to learn whether a prehabilitation program can improve recovery after major abdominal surgery in adults with cancer who are receiving treatment before surgery.
- Conditions
- Pancreatic Cancer, Colo-rectal Cancer, Gastric Cancer, Esophageal Cancer
- Trial name
- NCT07638410
- Testing
- Multidisciplinary Prehabilitation Program
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Fox Chase Cancer Center
Retrolaminar Block, TAP Block
Ultrasound Guided Retrolaminar Block Versus Transverse Abdominis Plane Block in Laparoscopic Upper Abdominal Surgeries
This study aims to compare and evaluate the safety and efficacy of ultrasound guided retrolaminar block versus transverse abdominis plane block in laparoscopic upper abdominal surgeries.
- Conditions
- Retrolaminar Block, TAP Block, Laparoscopic Abdominal Surgeries
- Trial name
- NCT07720817
- Testing
- Ultrasound-guided Retrolaminar Block group, Transverses Abdominis Plane (TAP) Block Group
- Where
- Egypt
- Volunteers
- 164 people
- Sponsor
- Mansoura University
Adhesions Abdominal, Surgery
Is Preoperative Prediction of Intra-Abdominal Adhesions Possible?
In this study, it was aimed to evaluate the presence of intra-abdominal adhesion with biochemical markers before the operation, as well as to determine whether there is a relationship between the severity of adhesion and…
- Trial name
- NCT06639906
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Manisa Celal Bayar University
Hypnosis, Preoperative Anxiety
Effect of Clinical Hypnosis in Preoperative Anxiety Among Patients Undergoing an Abdominal Surgery.
This Multicenter randomized controlled trial evaluates clinical hypnosis efficacy for reducing perioperative anxiety and postoperative pain in abdominal surgery patients across 3 Moroccan centers (n=48-68).
- Conditions
- Hypnosis, Preoperative Anxiety, Postoperative Pain, Abdominal Surgeries
- Trial name
- Hypnoanxiety (NCT07370974)
- Testing
- Clincal hypnosis
- Where
- 3 sites in Morocco
- Volunteers
- 48 people
- Sponsor
- HASSAN 1st university
Post Abdominal Surgery, Sepsis Abdominal
Clinical Effects of Ringers Lactate Versus Sterofundin/ Plasmalyte Solution in Patients With Sepsis
The goal of this clinical trial is to compare the clinical effects of using Ringer's Lactate and Sterofundin/ Plasmalyte as maintenance fluids in adult patients who have undergone abdominal surgery and are septic.
- Trial name
- NCT07239713
- Testing
- Ringer's Lactate Crystalloid Solutions, Sterofundin (Bolus of crystalloids)
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- CMH Lahore Medical College and Institute of Dentistry
Abdominal Surgery
Pip Care to Improve Surgical Patient Outcomes
Pip Care is developing a personalized, interactive surgical journey platform with a live health coach that works directly with health systems to optimize the perioperative care process.
- Trial name
- NCT06661291
- Testing
- Pip Care Digital Health Platform, Standard of Care Protocol
- Where
- 8 sites in United States
- Volunteers
- 900 people
- Sponsor
- University of Pittsburgh
Post Abdominal Surgery, Gastrointestinal Motility Disorder
Association Between Preoperative Mediterranean Diet Adherence and Postoperative Bowel Motility
Postoperative bowel motility is an important indicator of recovery after abdominal surgery and may be influenced by preoperative nutritional status.
- Conditions
- Post Abdominal Surgery, Gastrointestinal Motility Disorder, Postoperative Ileus
- Trial name
- NCT07808281
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Bahçeşehir University
Postoperative Pain, Postoperative Analgesia
A Predictive Model for Postoperative Analgesic Requirements After Abdominal Surgery
Postoperative pain remains a common challenge after abdominal surgery despite the use of standard multimodal pain management strategies.
- Conditions
- Postoperative Pain, Postoperative Analgesia, Opioid Analgesic Requirement, Pain Management After Abdominal Surgery
- Trial name
- NCT07803575
- Testing
- Intravenous Morphine Patient-Controlled Analgesia
- Where
- Malaysia
- Volunteers
- 65 people
- Sponsor
- Chaw Sook Hui
Abdominal Surgery, Postoperative Pain
External Oblique Intercostal Plane Block for Postoperative Analgesia After Major Upper Abdominal Surgery
Postoperative pain after laparoscopic major upper abdominal surgery (e.g., gastric, hepatic, gallbladder, pancreatic surgery) is often severe, and inadequate analgesia may lead to increased opioid use, opioid dependence, and poor…
- Trial name
- NCT07331441
- Testing
- External Oblique Intercostal Plane Block, Standard multimodal analgesia
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Jun Zhang
Postoperative Pain, Midline Laparotomy
Analgesic Outcomes of Ultrasound-Guided QLB vs TAP Block in Midline Laparotomy
This randomized controlled trial compares the analgesic efficacy of ultrasound-guided bilateral lateral quadratus lumborum block (QLB, QL1) versus ultrasound-guided bilateral transversus abdominis plane (TAP) block in adults…
- Conditions
- Postoperative Pain, Midline Laparotomy, Abdominal Surgery
- Trial name
- NCT07796828
- Testing
- Ultrasound-Guided Lateral Quadratus Lumborum Block (QL1), Ultrasound-Guided Transversus Abdominis Plane Block, Bupivacaine 0.25%
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Sheikh Zayed Medical College
Patients Undergoing Major Laparoscopic Abdominal Surgery
Intrathecal Morphine for Postoperative Analgesia in Major Laparoscopic Abdominal Surgery, a IMPACT-Scope Trial
The goal of this clinical trial is to learn the clinical and cost effectiveness of intrathecal morphine (ITM) in addition to usual care as a postoperative pain relief strategy following major laparoscopic abdominal surgery…
- Trial name
- IMPACT-Scope (NCT06666985)
- Testing
- ITM + Usual Care
- Where
- China
- Volunteers
- 700 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Cancer, Abdominal Cancer Surgery
Developing Pilot Postoperative Guidelines for Improved Functional Outcomes After High-Risk Cancer Surgery
The objective of this study is to develop and evaluate the implementation of novel timeline-specific National Comprehensive Cancer Network (NCCN)-style clinical guidelines designed to improve functional outcomes after high-risk…
- Conditions
- Cancer, Abdominal Cancer Surgery, Surgery, Recovery Outcomes
- Trial name
- NCT07720089
- Testing
- Algorithmic Guideline for Functional Recovery following Cancer Surgery
- Where
- 2 sites in United States
- Volunteers
- 66 people
- Sponsor
- University of Alabama at Birmingham
Abdominal Laparoscopic and/or Robotic Surgery, Local Anasthesia
Intraperitoneal Lidocaine and Bupivacaine for Postoperative Pain After Laparoscopic Surgery
The goal of this clinical trial is to determine the safety and efficacy of combined intraperitoneal local anesthetic instillation and port-site infiltration using lidocaine and bupivacaine in adults aged 18 to 60 undergoing…
- Conditions
- Abdominal Laparoscopic and/or Robotic Surgery, Local Anasthesia, Post Operative Pain, Acute, Lidocaine
- Trial name
- IPLA (NCT07775599)
- Testing
- Lidocaine, Bupivacaine
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Misr University for Science and Technology
Intra-abdominal Surgery, Anesthesia
Open Lung Protective Extubation Following General Anesthesia
Perioperative respiratory complications are a major source of morbidity and mortality. Postoperative atelectasis plays a central role in their development.
- Conditions
- Intra-abdominal Surgery, Anesthesia, Lung Injury, Ventilator-Induced Lung Injury
- Trial name
- OLEXT-3 (NCT06296173)
- Testing
- Protective "open-lung" extubation, Conventional extubation
- Where
- 5 sites in Canada
- Volunteers
- 270 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
ERAS, Gynecologic Surgery
Enhanced Recovery After Surgery (ERAS) in Patients Undergoing Gynecologic Surgery
Enhanced Recovery After Surgery (ERAS) is a multidisciplinary perioperative care program designed to reduce surgical stress, accelerate postoperative recovery, and improve clinical outcomes.
- Conditions
- ERAS, Gynecologic Surgery, Gynecologic Oncological Pelvic/Abdominal Surgery
- Trial name
- NCT07764276
- Testing
- Enhanced Recovery After Surgery (ERAS), Conventional Perioperative Care
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Abdominal Surgery, Postoperative Recovery
Effect of AI-Personalized Virtual Reality on Postoperative Recovery After Major Abdominal Surgery
Major abdominal surgery is frequently associated with postoperative pain, anxiety, delayed recovery, and prolonged hospitalization.
- Conditions
- Abdominal Surgery, Postoperative Recovery, Postoperative Pain, Length of Hospital Stay
- Trial name
- VR-RECOVER (NCT07493499)
- Testing
- Immersive Virtual Reality (VR), Standard Perioperative Care and Enhanced Recovery Protocol
- Where
- Egypt
- Volunteers
- 84 people
- Sponsor
- Alexandria University