Clinical trials: Ablation Treatment
Ventricular Tachycardia, Coronary Artery Disease
Trial Comparing Ablation With Medical Therapy in Patients With Ventricular Tachycardia
This study aims to compare antiarrhythmic drug therapy with catheter ablation using the SmartTOUCH catheter (Biosense Webster Inc.) as treatment for patients with ventricular tachycardia and coronary artery disease
- Trial name
- VeTAMed (NCT01798277)
- Testing
- Catheter Ablation, Medical therapy (sotalol or amiodarone)
- Sponsor
- Newmarket Electrophysiology Research Group Inc
Radiofrequency Ablation, Knee Arthritis Osteoarthritis
Comparison of the Effectiveness of Conventional and Pulse Radiofrequency Therapy in Advanced Knee Osteoarthritis in Elderly Patients: An Observational Study
Knee osteoarthritis (OA) is a very common joint disease, causing pain and loss of function. Osteoarthritis, including knee OA, is a significant cause of morbidity and disability in older adults and negatively impacts the…
- Trial name
- pain (NCT07113028)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Prostate Cancer
Investigating Efficacy and Safety of Two Degarelix Three-Month Dosing Regimens in Patients With Prostate Cancer Requiring Androgen Ablation Therapy
The study will have two treatment groups, evaluating two Degarelix doses. First dose is the initial dose followed by a maintenance dose given every three months.
- Trial name
- NCT00468286
- Testing
- Degarelix
- Where
- 29 sites in United States, Canada and 3 more
- Volunteers
- 133 people
- Sponsor
- Ferring Pharmaceuticals
Atrial Fibrillation
the Study of STABLE_SR for Persistent Atrial Fibrillation
Background:the ablation outcomes for the treatment of persistent atrial fibrillation are not as satisfactory as paroxsymal AF. The successful rate ranges from 30%-55%.
- Trial name
- STABLE-SR (NCT01761188)
- Testing
- Ablation
- Where
- China
- Volunteers
- 220 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Atrial Fibrillation
AtriCure Minimally Invasive Surgical Ablation for Atrial Fibrillation/RESTORE IIB
Feasibility study arm to evaluate the safety of adding the left atrial linear connecting lesions of the Cox-Maze lesion set to the current RESTORE SR II IDE study procedure of performing pulmonary vein isolation, selected left…
- Trial name
- RESTORE SR IIB (NCT00571779)
- Testing
- AtriCure Bipolar System
- Sponsor
- AtriCure, Inc.
Prostate Cancer
Androgen Ablation Therapy With or Without Vaccine Therapy in Treating Patients With Prostate Cancer
RATIONALE: Androgens can cause the growth of prostate cancer cells. Androgen ablation therapy, such as bicalutamide, leuprolide, and goserelin, may lessen the amount of androgens made by the body.
- Trial name
- NCT00771017
- Testing
- GVAX prostate cancer vaccine, bicalutamide, goserelin
- Sponsor
- Eastern Cooperative Oncology Group
Pancreatic Cancer
Clinical Study of Multimodal Ablation Remodeling Immunosensitized PD-1 in the Treatment of Pancreatic Cancer With Liver Metastasis
1. Clinical evaluation of multimodal ablation system for pancreatic cancer with hepatic metastatic malignancies. 2. Construction of a combined treatment system of multimodal ablation therapy combined with immunotherapy and…
- Trial name
- NCT06307080
- Testing
- Multi-mode thermal ablation device, Intravenous anti-PD-1 and chemotherapy
- Where
- China
- Volunteers
- 12 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Pancreatic Cancer, Pancreatic Neuroendocrine Tumor
Safety and Efficacy of an Ablation Catheter for the Treatment of Pancreatic Premalignant Cyctic Lesions.
This study aims to evaluate the safety and efficacy of new ablation catheter developed by MEDICAL TAEWOONG for the treatment of pancreatic premalignant and early malignant cystic lesion.
- Conditions
- Pancreatic Cancer, Pancreatic Neuroendocrine Tumor, Pancreatic Cyst, Pancreatic Cancer Stage
- Trial name
- yes (NCT03417843)
- Testing
- EUSRA RF electrode
- Volunteers
- 20 people
- Sponsor
- HaEmek Medical Center, Israel
Ventricular Premature Beats
Elimination of VPB With Ablation Versus Anti-arrhythmic Drug Treatment
The ECTOPIA trial is a randomized, multicenter, clinical trial to assess elimination of ventricular premature beats (VPB) with catheter ablation versus optimal anti-arrhythmic drugs (AAD) treatment with flecainide/verapamil or…
- Trial name
- ECTOPIA (NCT03845010)
- Testing
- Sotalol, Flecainide and verapamil, Catheter ablation
- Where
- Netherlands
- Volunteers
- 22 people
- Sponsor
- Maatschap Cardiologie Zwolle
Chronic Low Back Pain, Facet Joint Syndrome
MRgFUS and RFA for Treatment of Facet-joint Osteoarthritis Low Back Pain
This is a prospective, randomized, two-arm, phase II study. The purpose of this study is: To evaluate and compare the efficacy and safety of magnetic resonance-guided focused ultrasound (MRgFUS) and radiofrequency ablation (RFA)…
- Trial name
- NCT03168802
- Testing
- MRgFUS ablation, Radiofrequency ablation
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Taipei Medical University Hospital
Hepatocellular Carcinoma, Chemoembolization, Therapeutic
TACE+RFA Versus TACE Alone for Intermediate-stage Hepatocellular Carcinoma
The current standard treatment for intermediate-stage HCC (BCLC stage B) is transcatheter arterial chemoembolization (TACE) alone. The combination of TACE with RFA has also reported to be an effective treatment for HCC.
- Conditions
- Hepatocellular Carcinoma, Chemoembolization, Therapeutic, Ablation Techniques, RFA
- Trial name
- TORCH (NCT02435953)
- Testing
- TACE, RFA
- Where
- China
- Volunteers
- 241 people
- Sponsor
- Ming Zhao
Frozen Shoulder, Radiofrequency Ablation Treatment
The Efficacy of Suprascapular Nerve Radiofrequency and Intra-articular Steroid Injection in Frozen Shoulder Treatment
The aim of this clinical study is to compare the effectiveness of suprascapular nerve pulsed radiofrequency and intra-articular steroid injection in patients with frozen shoulder (adhesive capsulitis).
- Conditions
- Frozen Shoulder, Radiofrequency Ablation Treatment, Intra-articular Injection
- Trial name
- NCT06778577
- Testing
- intra-articular corticosteroid injection (IACI) group, suprascapular nerve radiofrequency group (SCNRFT)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara University
Hepatocellular Carcinomas
Multipolar Radiofrequency Ablation for Hepatocellular Carcinoma Using Extra Nodular Versus Intranodular Technique
The primary purpose of the trial is to demonstrate that at least a 40% drop of recurrence rate can be achieve in hepatocellular carcinoma patients treated with no touch multipolar radiofrequency ablation technique compared to…
- Trial name
- ARMCENVIN (NCT01008657)
- Testing
- Radiofrequency ablation
- Where
- France
- Volunteers
- 216 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dysfunctional Uterine Bleeding
Endometrial Ablation With Non-hysteroscopic Methods
Endometrial ablation in women with dysfunctional uterine bleeding using second generation ablation devices is a common widespread therapeutic approach.
- Trial name
- NCT01173965
- Testing
- MEA, Novasure
- Where
- 2 sites in Greece
- Volunteers
- 66 people
- Sponsor
- Aristotle University Of Thessaloniki
Atrial Fibrillation
Ground-Breaking Electroporation-based Intervention for PAROXysmal Atrial Fibrillation Treatment (BEAT PAROX-AF)
BEAT AF is a randomized controlled trial aiming to demonstrate that pulsed field energy is faster, more effective and safer (tissue selectivity) than RF for paroxysmal AF ablation
- Trial name
- BEAT PAROX-AF (NCT05159492)
- Testing
- PVI using PEF, PVI using CFRF
- Where
- 9 sites in Austria, Belgium and 3 more
- Volunteers
- 292 people
- Sponsor
- University Hospital, Bordeaux
Prostate Adenocarcinoma, Stage IIA Prostate Cancer AJCC v7
Leuprolide Acetate or Goserelin Acetate With or Without Vismodegib Followed by Surgery in Treating Patients With Locally Advanced Prostate Cancer
This randomized phase I/II trial studies giving leuprolide acetate or goserelin acetate together with or without vismodegib followed by surgery to see how well they work in treating patients with prostate cancer that has spread…
- Conditions
- Prostate Adenocarcinoma, Stage IIA Prostate Cancer AJCC v7, Stage IIB Prostate Cancer AJCC v7
- Trial name
- NCT01163084
- Testing
- Goserelin Acetate, Laboratory Biomarker Analysis, Leuprolide Acetate
- Where
- 5 sites in United States
- Volunteers
- 10 people
- Sponsor
- National Cancer Institute (NCI)
Heart Failure, Atrial Fibrillation
Cardiac Resynchronisation Therapy and AV Nodal Ablation Trial in Atrial Fibrillation Patients (CAAN-AF)
Cardiac resynchronization therapy (CRT) is a treatment for heart failure in patients who also suffer from ventricular dyssynchrony, a form of uncoordinated contraction of the ventricle (lower pumping chamber of the heart).
- Trial name
- CAAN-AF (NCT01522898)
- Testing
- AV nodal ablation, Medical Ventricular Rate Control
- Where
- 33 sites in Australia, Germany and 3 more
- Volunteers
- 145 people
- Sponsor
- University of Adelaide
Hepatocellular Carcinoma
Enumeration and Function Analysis of Treg Cells in Peripheral Blood of HCC Patients Before and After Ablation Therapy
The purpose of this study is to determine the enumeration and function changes of regulatory t cells in peripheral blood of hepatocellular carcinoma patients before and 1 week, 4 weeks after ablation therapy.
- Trial name
- NCT01668381
- Testing
- radiofrequency ablation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Atrial Fibrillation
Short Term Warfarin Therapy for Radiofrequency Catheter Ablation of Atrial Fibrillation
We hypothesized that in patients with low CHADS-VASc score (2 or < 2), there is no difference in thromboembolic or bleeding events between patients with short term warfarin therapy (2 weeks after catheter ablation) and…
- Trial name
- NCT01991951
- Testing
- warfarin
- Where
- South Korea
- Volunteers
- 520 people
- Sponsor
- Korea University Anam Hospital
Lung Cancer
ENB-guided Ablation Therapy Combined With VATS in the Treatment of MPLC
The study is designed as a prospective trial whose purpose is to evaluate the effectiveness and safety of ENB-guided ablation therapy combined with VATS in the treatment of multiple primary lung cancers (MPLC).
- Trial name
- NCT04730453
- Testing
- ENB-guided ablation therapy combined with VATS
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Chest Hospital