Clinical trials: Abortion, Medical
Abortion, Medical
The Misoprostol-Only Regimen Evidence Study
The goal of this study is to evaluate the effectiveness, non-inferiority, and side-effect profile of an updated misoprostol-only regimen, as compared to the combined mifepristone-misoprostol regimen, among people seeking…
- Trial name
- MORE (NCT07174856)
- Testing
- Misoprostol-only medication abortion regimen, Combined regimen
- Where
- United States
- Volunteers
- 1,900 people
- Sponsor
- Ibis Reproductive Health
Abortion in Second Trimester
Outpatient Service for Mid-trimester Termination of Pregnancy
This study seeks to evaluate the safety, acceptability and feasibility of an outpatient "day procedure" for medical abortion at 13-18 weeks gestation.
- Trial name
- NCT03346629
- Testing
- Mifepristone + Misoprostol
- Where
- 3 sites in Nepal
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
IUC Insertion After Medical Abortion
Intrauterine Contraception (IUC) After Medical Abortion
Today a large proportion of early abortions are medical, in accordance to the woman's choice. The main objective of the present study was to compare, in a randomised fashion, initiation of intrauterine contraception (IUC) at…
- Trial name
- NCT01537562
- Testing
- Timing of IUC insertion
- Where
- Sweden
- Volunteers
- 129 people
- Sponsor
- Karolinska Institutet
Termination of Pregnancy, Supportive Care
NAVIGATION ASSISTED CARE PROGRAM AND TERMINATION OF PREGNANCY
This study was planned to evaluate the effectiveness of the navigation-assisted care program based on the Swanson Theory of Care, which was developed for women who underwent medical termination as a result of a complication…
- Conditions
- Termination of Pregnancy, Supportive Care, Nursing Caries
- Trial name
- NCT05326854
- Testing
- supportive care
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Medical Abortion
'No-test' Tele-abortion: a Multi-centre Randomised Controlled Trial
Brief Summary The goal of this clinical trial is to learn whether a no-test telemedicine medical abortion model can provide abortion care that is as effective and safe as standard clinic-based medical abortion care among women…
- Trial name
- OPTIMISE (NCT07868991)
- Testing
- no-test medical abortion, Standard Care (in control arm)
- Where
- 10 sites in Sweden
- Volunteers
- 978 people
- Sponsor
- Karolinska Institutet
Abortion, Induced
Pilot Study of the Addition of Osmotic Dilators to Preparation Prior to Labor Induction Abortion
One the day prior to medical abortion (labor induction) in the second trimester, insertion of osmotic dilators is added to the routine procedures.
- Trial name
- DAIS (NCT00855842)
- Testing
- osmotic dilator insertion
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Boston University
Abortion, Drug-Induced, Pharmacies
Evaluating an Intervention to Increase Use of Call Centre Support for Self-managed Medical Abortion
Self-management of medical abortion (MA) pills purchased from pharmacies is considered to be one of the reasons behind falling morbidity and mortality from unsafe abortion in recent years.
- Trial name
- NCT03248050
- Testing
- Pharmacy encouraged to promote call centre use to clients
- Volunteers
- 1,359 people, healthy volunteers welcome
- Sponsor
- Marie Stopes International
Complete Miscarriage
Use of Letrozole Pretreatment With Misoprostol for First-Trimester Medical Abortion
The purpose of this study is to compare the success rate of letrozole and misoprostol versus misoprostol alone for medical termination of first trimester pregnancy.
- Trial name
- NCT02401425
- Testing
- Letrozole, Misoprostol
- Where
- Egypt
- Volunteers
- 423 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Second Trimester Abortion
Pilot Study of an Ambulatory Medical Abortion Service at 13-18 Weeks of Gestation in Colombia
This pilot study seeks to evaluate the safety, acceptability and feasibility of a shortened outpatient procedure for medical abortion at 13-18 weeks gestation.
- Trial name
- NCT04063904
- Testing
- Mifepristone, Misoprostol
- Where
- Colombia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical Abortion, Complete or Unspecified, Without Complication
Randomized Study of Letrozole and Trilostane for Medical Abortion
In menstruation an effective shedding of the endometrial lining occurs. Both progesterone and estrogen levels fall sharply at this time.
- Trial name
- NCT01615211
- Testing
- Letrozole, Trilostane
- Where
- Sweden
- Volunteers
- 36 people
- Sponsor
- Kristina Gemzell Danielsson
Abortion, First Trimester
Acceptability and Feasibility of a Demedicalized Medical Abortion Regimen in the Caucasus
This study examined the acceptability and feasibility of using a simplified regimen of medical abortion in Armenia and Azerbaijan.
- Trial name
- NCT02219100
- Testing
- Home administration of 200 mg mifepristone
- Where
- 5 sites in Armenia, Azerbaijan
- Volunteers
- 613 people
- Sponsor
- Gynuity Health Projects
Medical; Abortion, Fetus
Simplified Medical Abortion Screening: A Pilot Demonstration Project
This study aims to collection additional data on the safety and acceptability of medical abortion without pretreatment pelvic ultrasound or exam in woman who meet certain criteria.
- Trial name
- NCT02381223
- Where
- 5 sites in United States, Mexico and 1 more
- Volunteers
- 409 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical; Abortion, Fetus
Comparison of Telephone Follow-up With In-person Follow-up After Medical Abortion
Background: Medical abortions in Canada are provided using a standard regimen of methotrexate and misoprostol. After these medications are administered, patients are most commonly checked for termination of the pregnancy with an…
- Trial name
- NCT01943279
- Testing
- Remote Follow-up (RFU), Standard Follow-up (SFU)
- Where
- 2 sites in Canada
- Volunteers
- 139 people
- Sponsor
- Women's College Hospital
Complete Abortion
Comparing Two Regimens for Medical Abortion: Mifepristone + Misoprostol Versus Misoprostol Alone
This double blinded, placebo-controlled randomized trial will compare the safety, efficacy and acceptability of two medical abortion regimens up to 63 days since last Menstrual Period (LMP) in Tunisia and Vietnam.
- Trial name
- NCT01387256
- Testing
- medical abortion
- Where
- 2 sites in Tunisia, Vietnam
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Medical; Abortion, Fetus
Mifepristone and Misoprostol for the Termination of Pregnancy up to 70 Days Gestation
The purpose of this study is to determine the efficacy and acceptability of a regimen of 200 mg mifepristone (Zacafemyl), followed 24-48 hours later by 800 mcg of buccal misoprostol.
- Trial name
- NCT01966874
- Where
- United States
- Volunteers
- 1,001 people
- Sponsor
- Gynuity Health Projects
Medical Abortion
Routine Follow-up Versus Self-assessment in Medical Abortion
The main objective of the study is to optimize the routines for follow-up after medical abortion in order to give women more autonomy by reducing the number of consultations involved and to reduce the frequency of postabortal…
- Trial name
- NCT01487213
- Testing
- Home self assessment of complete medical abortion
- Where
- 4 sites in Austria, Finland and 2 more
- Volunteers
- 929 people
- Sponsor
- Karolinska Institutet
Pregnancy, Violence Against Women (VAW)
Requests for Voluntary Termination and Medical Termination of Pregnancy for Maternal, Psychological or Social Reasons At the Women's Center ( La Maison Des Femmes) in Saint-Denis :
In France, Article L2213-1 of the Public Health Code (law of July 4, 2001) clearly establishes that "voluntary termination of pregnancy may be performed at any time if two doctors, who are part of a multidisciplinary team…
- Conditions
- Pregnancy, Violence Against Women (VAW), Violence, Abortion
- Trial name
- NCT06708208
- Where
- France
- Volunteers
- 107 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Genital Diseases, Female, Ectopic Pregnancy
Randomized Study of a Dematerialized Management for Post-Emergency Gynecological Follow-Up
The GYNAB study aims to compare patient satisfaction and clinical outcomes between dematerialized post-emergency gynecological follow-up using a connected health app and traditional in-person follow-up. Conducted by Drs.
- Conditions
- Genital Diseases, Female, Ectopic Pregnancy, Uncertain Viability of Pregnancy, Abortion, Missed
- Trial name
- GYNAB (NCT06615843)
- Testing
- Participants will receive post-emergency gynecological follow-up at home using a connected health app
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Abortion, Second Trimester, Abortion, Medical
Foley Balloon for Cervical Preparation Before Dilation and Evacuation
To evaluate the Foley Balloon technique for cervical preparation before second trimester surgical abortion between 16 and 21 weeks estimated gestational age in combination with misoprostol to prepare the cervix before dilation…
- Trial name
- NCT06850974
- Testing
- Foley Balloon Catheter, Misoprostol, Laminaria
- Where
- Mozambique
- Volunteers
- 102 people
- Sponsor
- Stony Brook University
Infertility, Intellectual Disability
Prospective Study to Assess Medical Performance of Optical Mapping and Long Read Sequencing in Detecting Numerical and Structural Chromosome Abnormalities
Chromosomal aberrations are major causes of developmental disorders (Intellectual disability (ID), multiple congenital anomalies (MCA), autism spectrum disorders (ASD)) as well as reproductive disorders (RD) in particular…
- Conditions
- Infertility, Intellectual Disability, Malformation, Miscarriage
- Trial name
- CHROMAPS (NCT05290051)
- Testing
- Optical Genome Mapping (Bionano®), Longread sequencing (Nanopore®)
- Where
- France
- Volunteers
- 350 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France