Clinical trials: Abrasion
Corneal Abrasion, Eye Trauma
Bandage Contact Lenses for Corneal Abrasions
Two percent of all patients presenting to the Emergency Departments have complaints involving the eye. Corneal abrasions are a common diagnosis with patients with eye pain and often cause significant discomfort.
- Trial name
- NCT03206723
- Testing
- Bandage contact lens, Eyedrop, Hydrocodone
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Vitiligo
Fractional Laser in Combination With UVB Therapy in Vitiligo Patients
Rationale: Vitiligo is a common skin disorder that can impair a patient's quality of life. Many depigmented lesions in vitiligo patients remain therapy resistant for medical treatment.
- Trial name
- NCT02290717
- Testing
- Fractional CO2 laser, NB-UVB therapy, Fluticasone Propionate Cream 0.05%
- Where
- Netherlands
- Sponsor
- Netherlands Institute for Pigment Disorders
Corneal Abrasion
Treatment of Corneal Abrasions With Topical Tetracaine
Corneal abrasion (CA) is one of the most common eye injuries, accounting for 10% of eye-related emergency visits.1 A 1985 survey showed that around 3% of all visits to US general practitioners were for corneal abrasions.
- Trial name
- NCT02771392
- Testing
- Ophthalmic Tetracaine, Normal Saline
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- New York Presbyterian Brooklyn Methodist Hospital
Blister, Abrasion
Assessing Foot Injuries in Infantry Recruits Wearing Different Boots
One hundred infantry recruits will be randomly assigned to two groups. Injuries will be monitored.
- Conditions
- Blister, Abrasion, Stress Fracture, Ankle Sprain
- Trial name
- NCT02810002
- Testing
- Experimental infantry boot - DEFINITE-REGULATOR, Control infantry boot
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Irritation Potential of Topic Agent
A Study to Evaluate the Irritation Potential of ATx201 in Healthy Volunteers
This is a Phase I single-site study to evaluate the irritation potential of topically applied ATx201 GEL, 2% and 4%, along with positive and negative control and placebo control (ATx201 GEL Placebo), in healthy human subjects on…
- Trial name
- NCT03301870
- Testing
- ATx201 Gel 2%, ATx201 Gel 4%, Positive Control
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- UNION therapeutics
Endodontic Diagnosis, Endodontic Diseases, Endodontic Treatment, Endodontic Decision-making
LLM Performance in Endodontic Diagnostics
The goal of this prospective observational study is to evaluate the ability of three large language models (ChatGPT-4o, Gemini Advanced, and Claude 3.7) to support diagnosis and treatment decision-making in adult patients…
- Trial name
- NCT07281066
- Testing
- AI-Based Diagnostic Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Malignant Pleural Effusion, Thoracic Cancer
Video Assisted Thoracoscopic Surgery (VATS) - Surgical Pleurodesis vs Tube Drainage in Management of Malignant Pleural Effusion (MPE)
Malignant Pleural Effusion (MPE) is considered to be a common presentation at malignant tumors representing 15% of all cancer cases. It carries a burden on our patients with dyspnea being the most common symptom in most of cases.
- Trial name
- NCT05872126
- Testing
- VATS-Surgical pleurodesis, Tube Drainage
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Other Abnormal Granulation Tissue Nos
Granulation Tissue Treatment: Silver Nitrate vs Kenalog vs Washcloth Abrasion
Granulation tissue, or excess tissue, forms around gastrostomy tube sites and is a common problem seen in the pediatric surgery population.
- Trial name
- NCT02519738
- Testing
- Silver Nitrate, Kenalog (Triamcinolone), Washcloth Abrasion
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Striae Distensae
Striae Distensae Treatment Using Deep Skin Abrasion
The goal of this clinical trial is to learn if a device works to treat striae distensae. It will also learn about the safety of the device. The main questions it aims to answer are: 1.
- Trial name
- NCT07087405
- Testing
- Striae Distensae Treatment Device
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Boston Children's Hospital
Periodontal Diseases
Efficacy of Subgingival Erythritol Air Polishing in Treatment of Periodontal Pockets
Periodontitis is an inflammation associated with destruction of the periodontium that ultimately, if not treated, leads to tooth loss.
- Trial name
- NCT05798871
- Testing
- Subgingival erythritol air polishing, Conventional root planing
- Where
- Iraq
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Biofilm Removal, Gingival Abrasion
Capacity of Biofilm Removal and Gingival Abrasion After Utilization Medium and Soft Toothbrushes
This study compared the removal of dental biofilm between soft and medium toothbrushes. The patients refrained from performing mechanical or chemical plaque control for 96 hours to allow dental biofilm accumulation on the tooth…
- Trial name
- NCT01125007
- Testing
- Two kind toothbrushes
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Franciscan University Center
Skin Abrasion, Superficial Wound
Evaluation of the Tolerance of the Medical Device RL3010A - DP0378 in Children and Adults Presenting a Superficial Wound After a Dermatological Procedure
The CE-marketed medical device class IIa RL3010A - DP0378 developed by Pierre Fabre Laboratories is indicated in the treatment of superficial wounds and abrasions.
- Trial name
- NCT06016803
- Testing
- Cicatryl (RL3010A - DP0378)
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Pierre Fabre Dermo Cosmetique
Corneal Abrasions
Proparacaine vs Placebo for Corneal Injuries
Introduction: Traumatic injuries to the outer covering of the eye (the cornea) are a common emergency department complaint. They cause significant patient distress including pain, loss of sleep and missed work days.
- Trial name
- Dogma (NCT00620997)
- Testing
- Proparacaine drops 0.05%, saline drops
- Where
- Canada
- Volunteers
- 43 people
- Sponsor
- London Health Sciences Centre
Coronary Heart Disease, Type-2 Diabetes
Effects of Milk Derived From Mountain-pasture Grazing Cows on Risk Markers of the Metabolic Syndrome Compared to Conventional Danish Milk
To investigate the effect of milk delivered from mountain-pasture grazing cows on risk markers of the metabolic syndrome and type-2 diabetes with the effect of conventional Danish milk.
- Trial name
- NCT01343589
- Testing
- milk fat
- Where
- Denmark
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Periodontal Diseases, Tooth Abrasion
The Effect of Bristle Brush, Rubber Cup, and Air Polishing on Tooth Surface Roughness of Scaled Teeth
This study investigates the effects of three polishing methods using a bristle brush, rubber cup, and air polishing on the surface roughness of scaled human teeth.
- Conditions
- Periodontal Diseases, Tooth Abrasion, Dental Plaque
- Trial name
- NCT06857474
- Testing
- Bristle Brush Polishing, Rubber Cup Polishing, Air Polishing
- Where
- Pakistan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Teeth With Root Canal Treatment
Post-endodontic Access Cavity Cleaning Techniques
Aim This study aims to evaluate the effectiveness of different post-endodontic access cavity cleaning techniques (PACCTs) in removing residual epoxy resin-based root canal sealer from the pulp chamber floor following root canal…
- Trial name
- NCT06937424
- Testing
- Dry cotton pellet group, Ethanol-saturated cotton pellet 7 seconds group, Ethanol-saturated cotton pellet visibly clean group
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Marmara University
Neuromuscular Blockade, Intraoperative Monitoring
Gentle Skin Abrasion and EMG-Based Neuromuscular Blockade Monitoring
This study will evaluate whether gentle skin abrasion improves electromyographic signal quality during neuromuscular blockade monitoring in adult surgical patients.
- Conditions
- Neuromuscular Blockade, Intraoperative Monitoring, Skin Preparation, Electromyography
- Trial name
- NCT07759206
- Testing
- Gentle Skin Abrasion Before EMG-Based Neuromuscular Blockade Monitoring
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Minnesota
Abrasion, Discoloration, Tooth
Enamel Abrasion and Stain Removal Efficacy
Enamel abrasion and stain removal efficacy of two whitening toothpastes
- Trial name
- NCT05619315
- Testing
- Charcoal -based whitening toothpaste, Calcium carbonate /perlite containing whitening toothpaste.
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cairo University
Gingival Abrasion
Assessment of a Sonic Toothbrush on the Abrasion of the Gingival Tissue
This is a randomized, monocentric, examiner-blind, two-arm, parallel, controlled clinical research study. It aims to assess gingival abrasion by the comparison of pre- to- post-brushing after a single brushing and after 12 weeks…
- Trial name
- ASTA (NCT05375227)
- Testing
- Teeth brushing
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Philips France Commercial
Tooth Abrasion, Gingival Recessions
The Effect of Retraction Cord on the Surrounding Periodontal Tissues in Restorative Treatment
The goal of this clinical trial is to learn whether a retraction cord affects gum health when used during tooth restoration procedures.
- Conditions
- Tooth Abrasion, Gingival Recessions, Non-Carious Cervical Lesions (NCCLs), Periodontal Health
- Trial name
- NCT07734935
- Testing
- Gingival Retraction Cord, Composite Resin Restorative, Universal Adhesive - G-Premio Bond
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people
- Sponsor
- Istanbul University