Clinical trials: Absorption; Iron
Iron Absorption
The Effects of Acute Erythropoietin on Hepcidin and Dietary Iron Absorption Following Military-relevant Exercise in Energy Deficit: Pilot Study
Military personnel frequently experience declines in iron status during training and when in the field, which may compromise performance.
- Trial name
- IRON BOOST (NCT07517562)
- Testing
- Exercise test
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Dysmetabolic Iron Overload Syndrome, Genetic Hemochromatosis
Effects of Polyphenols on Iron Absorption in Iron Overload Disorders.
Dysmetabolic iron overload syndrome and genetic hemochromatosis are frequent causes of iron overload. Polyphenols are efficient iron-chelators.
- Conditions
- Dysmetabolic Iron Overload Syndrome, Genetic Hemochromatosis, Iron Absorption, Polyphenols
- Trial name
- POLYFER (NCT03453918)
- Testing
- polyphenols
- Where
- France
- Volunteers
- 41 people
- Sponsor
- University Hospital, Clermont-Ferrand
Iron Deficiency (ID), Iron Absorption
Iron Absorption From Plant Heme Iron
Heme, an iron protoporphyin IX complex, consists of a ferrous ion captured in a porphyrin ring acting as a tetradentate ligand. The unique features of heme iron -its unusually high absorption in foods and its resistance to…
- Trial name
- PHIA (NCT07143890)
- Testing
- Iron chlorophyllin + no-matrix, SoyHb + no-matrix, FeSO4 + no-matrix
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- ETH Zurich
Zinc Absorption, Iron Absorption
Guatemala Biofortified Maize Study
Zinc (Zn) and iron (Fe) deficiencies are common in Guatemala, and maize is a staple food throughout the country. The primary aim of this study is to demonstrate if utilizing nixtamalized biofortified maize has the potential to…
- Trial name
- NCT06650397
- Testing
- Biofortified maize
- Where
- Guatemala
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Iron Absorption
Dietary Iron Requirements
Dietary Reference Intakes (DRIs) for iron are based on a relatively small number of studies in European populations. This research study will determine iron needs in a representative sample of adults living in the US using the…
- Trial name
- NCT07139821
- Testing
- Stable iron isotope
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Gut -Microbiota, Inflamation
Impact of a Cricket and Black Soldier Fly Larvae-Fortified Cracker on the Gut Microbiome and Iron Status in Malagasy Schoolchildren
The purpose of this study is to determine the health impacts of consistent consumption of insect-fortified crackers among school-aged children in Madagascar.
- Conditions
- Gut -Microbiota, Inflamation, Iron Absorption
- Trial name
- NCT07439185
- Testing
- Cricket and Black Soldier Fly Larvae-fortified Cracker, Rice and Corn Cracker
- Where
- Madagascar
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Cornell University
Zinc Absorption, Iron Absorption
Zinc and Iron Absorption From Common Beans in Young Adult Women
Fifteen female study participants will be enrolled in a randomized crossover study to measure fractional and total zinc and iron absorption from four common bean (Phaseolus vulgaris) varieties with varying phytate and…
- Trial name
- NCT06327529
- Testing
- SER 118, LMP 1001, LPA 586
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Iron Absorption, Iron Requirements
Determination of Iron Absorption and Losses in People Living at High Altitude to Investigate the Requirements in This Population Group Using a Newly Developed Technique
Iron is an essential micronutrient responsible for a whealth of biological processes of the human body. Iron plays a fundamental role especially in oxygen transport, by binding to hemoglobin in the blood circulation.
- Conditions
- Iron Absorption, Iron Requirements, Altitude
- Trial name
- ARIA (NCT07142590)
- Testing
- Stable Isotopes
- Where
- Switzerland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Diego Moretti
Iron Absorption, Iron Deficiencies
Maximizing the Benefits of Iron in Ready-to-Use Therapeutic Foods for Malnourished Children in Kenya
Reports from the Kenya Red Cross Society (KRCS) in Kwale County, southern Kenya, indicate a limited impact of Ready-to-Use Therapeutic Foods (RUTFs) on malnutrition or anemia.
- Conditions
- Iron Absorption, Iron Deficiencies, Severly Acutely Malnourished Children, Malnutrition in Children
- Trial name
- SAMI (NCT07315295)
- Testing
- Iron absorption from RUTF on Day 0, Treatment with RUTF for 80 days, Iron absorption from RUTF on Day 20
- Where
- 2 sites in Kenya, Switzerland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- ETH Zurich
Anemia, Iron Deficiency (Without Anemia)
The Immediate and Long-term Effects of a Novel Marine-based Iron Supplement in Adult Females
The goal of this study is to identify how well a fish-based iron supplement is absorbed and to learn how many, if any, digestive related side effects are caused by ingesting the supplement.
- Conditions
- Anemia, Iron Deficiency (Without Anemia), Iron Absorption
- Trial name
- NCT07199244
- Testing
- marine-based heme iron
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Nutraceuticals Research Institute
Sleep, Inadequate, Energy Deficit
The Effects of Repeated Operational Stress and Limited Recovery on Resilience Capacity
This longitudinal study will examine the effects of repeated bouts of operational stress and limited recovery on integrated MPS, whole-body protein balance, iron absorption, and aerobic performance.
- Conditions
- Sleep, Inadequate, Energy Deficit, Iron Absorption, High Physical Activity
- Trial name
- REP DEF (NCT06784544)
- Testing
- Operational Stressors
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Diabetes Mellitus Type 2, Iron Absorption
Semaglutide and Intestinal Iron Absorption
Semaglutide belongs to a group of long-acting glucagon-like peptide 1 receptor agonists (GLP-1). Disorders in iron absorption have been linked to numerous medication, dietary, and nutrient interactions thus far.
- Trial name
- NCT06629688
- Testing
- semaglutide
- Where
- Croatia
- Volunteers
- 51 people
- Sponsor
- University Hospital Dubrava
Iron-deficiency, Ferritin Threshold
Defining the Serum Ferritin Concentration in Kenyan Women at Which the Body Senses Iron Depletion and Begins to Upregulate Iron Absorption
The serum or plasma ferritin concentration (referred to hereafter as ferritin) is the most widely used indicator to detect iron deficiency and a low ferritin indicates depleted iron stores.
- Conditions
- Iron-deficiency, Ferritin Threshold, Iron Absorption, Stable Iron Isotopes
- Trial name
- NCT05266703
- Testing
- Isotopically labelled iron sulfate 15mg
- Where
- Kenya
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Requirements, Pregnancy
Iron Absorption and Requirements in Pregnancy and Lactation
Iron requirements increase significantly during pregnancy. Current recommendations for iron intake in pregnant and lactating women (PLW) are mainly based on factorial estimates and extrapolated from non-PLW.
- Conditions
- Iron Requirements, Pregnancy, Lactation, Infancy
- Trial name
- PILLAR_II (NCT05973552)
- Testing
- CO-rebreathing, Oral iron isotope administration (54Fe), Intravenous iron isotope administration (58Fe)
- Where
- Kenya
- Volunteers
- 250 people
- Sponsor
- University of Oxford
Iron Absorption
Iron Absorption From an Iron-fortified Follow-up Formula With Added Synbiotic or Human Milk Oligosaccharides
The co-primary objectives of this study are: 1) to investigate the effect adding a synbiotic (combination of a pre-and probiotic) to iron-fortified follow-up formula (FUF) on iron bioavailability, and 2) to investigate the effect…
- Trial name
- NCT04774016
- Testing
- Test formula A without added pre- and pro-biotic, Test formula B with synbiotic, Test formula C with HMOs
- Where
- Thailand
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Iron Absorption
Iron Absorption in Vegetarian Children
Few areas are more controversial in pediatric nutrition than the role of a vegetarian diet for children. Advocates make strong health claims whereas others have expressed safety concerns, especially regarding iron nutrition.
- Trial name
- NCT01489007
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Iron Absorption, Bariatric Surgery
Iron Absorption Trial
Introduction: There are indications that the absorption of oral iron supplementation is reduced after a Roux- en -Y gastric bypass.
- Conditions
- Iron Absorption, Bariatric Surgery, Roux- en -y Gastric Bypass
- Trial name
- NCT02228902
- Testing
- Ferrous fumarate, Ferrous gluconate
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Rijnstate Hospital
Iron Absorption, Gut Microbiota
Iron Absorption From a Wheat-based Instant Cereal:Gut and Stable Isotope Studies in Kenyan Infants
The aim of this study is to measure the effect of a prebiotic (high dose/low dose) mixture at different doses within a wheat-based instant cereal, on fractional iron absorption (FIA), gut microbiota and inflammation after three…
- Trial name
- NCT03894358
- Testing
- FeFum and 7.5 g prebiotic mixture, FeFum and 3 g prebiotic mixture, Fefum and no prebiotic mixture
- Where
- Kenya
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency, Anemia; Deficiency, Nutritional, With Poor Iron Absorption
A Study to Investigate the Effect of Vitamin D3 Supplementation on Iron Status in Iron Deficient Women
Iron is one of the most vital elements in humans as it plays a role in physiological functions such as transferring and storing oxygen, transporting electrons and catalysing numerous reactions, from oxidative metabolism to…
- Conditions
- Iron Deficiency, Anemia; Deficiency, Nutritional, With Poor Iron Absorption, Vitamin D Deficiency
- Trial name
- NCT02714361
- Testing
- Vitamin D3 supplement
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Chester
Iron Absorption
Iron Long-Term Labelling Study Malawi
Conventional indirect indicators of iron status, using serum and red blood cell biomarkers, are confounded by inflammation from common infections in sub-Saharan Africa, a region with a high prevalence of iron deficiency, making…
- Trial name
- NCT02977806
- Where
- Malawi
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Prof. Michael B. Zimmermann