Clinical trials: Abuse Physical
Adolescent Behavior, Interpersonal Relationships
It's Your Game: An Innovative Approach to Preventing Teen Dating Violence
The purpose of this study is to evaluate Me \& You: Building Healthy Relationships, a classroom- and computer-based healthy relationships and dating violence prevention curriculum for 6th grade students, in a large, urban public…
- Conditions
- Adolescent Behavior, Interpersonal Relationships, Domestic Violence, Physical Violence
- Trial name
- NCT03482687
- Testing
- Me & You: Building Healthy Relationships
- Where
- United States
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Human Abuse Potential
Assessment of Abuse Potential of Cebranopadol in Humans
This study will be conducted to evaluate the abuse potential of single doses of cebranopadol as compared with oxycodone, tramadol and matching placebo in recreational drug users.
- Trial name
- NCT05256108
- Testing
- Oxycodone 40 mg, Tramadol 600 mg, Cebranopadol 600 µg
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Tris Pharma, Inc.
Mental Health Issue, Family Relations
An Evaluation of a Family Counseling Intervention ("Tuko Pamoja") in Kenya
The purpose of this study is to evaluate a family counseling intervention, entitled "Tuko Pamoja" (Translation "We are Together" in Kiswahili).
- Conditions
- Mental Health Issue, Family Relations, Family Conflict, Child Mental Disorder
- Trial name
- C0058 (4C) (NCT06417918)
- Testing
- Tuko Pamoja, "We are Together" in Kiswahili
- Where
- Kenya
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Duke University
Smoking, Alcohol Abuse
Dynamic Assessment and Referral System - Evaluation
The investigators study will use a randomized controlled design. Eligible and consenting participants will be randomly assigned to one of two conditions: (1) DARSSA Intervention condition, or (2) Minimal Intervention Control…
- Conditions
- Smoking, Alcohol Abuse, Drug Abuse
- Trial name
- DARSSA (NCT01153373)
- Testing
- Self-administered computerized assessment for tobacco, substance abuse, and alcohol use., Self-Administered Computerized Assessment and Counseling for Tobacco, Alcohol, and Substance Abuse
- Where
- United States
- Volunteers
- 758 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Adolescent Behavior, Emergency Department
Emergency Department Healthcare Education Assessment and Response for Teen Relationships: A Pilot Feasibility Study
This is a single-site, randomized, controlled trial. Investigators will evaluate feasibility of the Emergency Department Healthcare Education Assessment and Response for Teen Relationships (ED-HEART) intervention among…
- Conditions
- Adolescent Behavior, Emergency Department, Abuse Physical, Abuse Mental
- Trial name
- ED-HEART (NCT05194202)
- Testing
- ED-HEART
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Sleep
Cannabis Association With Sleep Study
The purpose of this study is to learn more about cannabis use, sleep, and stress, and whether there is any relationship between the three.
- Trial name
- CaSS (NCT06982950)
- Testing
- Manipulation of Sleep Duration
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Abdominal Injuries, Physical Abuse
Effectiveness of Contrast-Enhanced Ultrasound
The purpose of the study is to generate pilot data describing test characteristics of contrast enhanced ultrasound in young children with concern for abdominal trauma.
- Conditions
- Abdominal Injuries, Physical Abuse, Accidental Fall, Motor Vehicle Injury
- Trial name
- NCT03473249
- Testing
- Contrast-Enhanced Ultrasound using Lumason
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Child Sexual Abuse, Suspected
Preparing Caregivers for the Child Sexual Abuse Examination: Are Informational Leaflets Helpful?
Children are typically inadequately prepared for the sexual abuse medical examination. Caregivers report lack of examination knowledge as a barrier to preparing their children.
- Trial name
- NCT01850407
- Testing
- Education Counseling
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Hackensack Meridian Health
Nursing Education, Simulation of Physical Illness
Moulage Technique in Child Abuse Recognition
Early recognition of physical abuse in children is essential for ensuring child safety and preventing further harm. However, distinguishing abuse-related injuries from accidental findings can be challenging, especially for…
- Conditions
- Nursing Education, Simulation of Physical Illness, Child Physical Abuse, Suspected, Sequela
- Trial name
- Moulage (NCT07509723)
- Testing
- Moulage Technique Group, movie group
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Atlas University
Opioid Abuse, Prescription Opioid Abuse
Community Pharmacy-Based Prescription Drug Monitoring Program Opioid Risk Assessment Tool
This goal of this observational study is to develop and test the Opioid Risk Reduction Clinical Decision Support (ORRCDS) tool. The tool will be an opioid medication risk screener and decision support platform that will be used…
- Trial name
- PharmTool (NCT05706311)
- Testing
- Clinical Decision Support Tool (Moderate Risk), Clinical Decision Support Tool (High Risk), Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Utah
Nicotine Dependence
Lab to Real World Assessment of E-cigarette Abuse Liability and Appeal
The proposed research is a longitudinal human lab study to examine how measures of abuse liability and product appeal vary by e-cigarette device type, and how these lab assessments may predict subsequent e-cigarette and other…
- Trial name
- NCT02520349
- Testing
- MarkTen and e-Go e-cigarettes
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Truth Initiative
Narcotic Abuse, Opioid-related Disorders
Abuse Potential Assessment of Intranasally Administered EMBEDA Compared To Morphine Sulfate Controlled Release And Placebo
This was a single-dose, randomized, double-blind, placebo-controlled, 3 way crossover study designed to evaluate the relative abuse potential of crushed EMBEDA® compared to morphine sulfate CR tablets and placebo in healthy male…
- Conditions
- Narcotic Abuse, Opioid-related Disorders, Analgesia, Chronic Pain
- Trial name
- NCT01595867
- Testing
- EMBEDA - morphine sulfate/ naltrexone hydrochloride, morphine sulfate CR crushed.
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Pfizer
Human Abuse Potential
Assessment of Abuse Potential of Rapastinel in Humans
Based on the pharmacological class of rapastinel, this study will be conducted to evaluate the abuse potential of single doses of rapastinel as compared with ketamine, a NMDAR antagonist that is a Schedule III dissociative…
- Trial name
- NCT03799900
- Testing
- Rapastinel, Ketamine
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Naurex, Inc, an affiliate of Allergan plc
Alcohol Drinking, Cannabis Use
Cannabis' Impact on Alcohol Consumption
This study employs a repeated measures experimental design to examine the effect of THC-dominant dose of cannabis and CBD-dominant dose of cannabis, relative to placebo, on subsequent drinking in an alcohol choice task in which…
- Conditions
- Alcohol Drinking, Cannabis Use, Cannabis, Alcohol Use Disorder
- Trial name
- NCT05389930
- Testing
- THC-dominant cannabis, CBD-dominant cannabis, Alcohol
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Brown University
Cannabis, Ketamine
THC and Ketamine Effects in Humans: Relation to Neural Oscillations and Psychosis
The aim of the research protocol is to evaluate cannabinoid-glutamate interactions in humans. As part of this aim the investigators will assess the safety and tolerability of the combination of NMDA antagonist, ketamine, and the…
- Trial name
- NCT04199468
- Testing
- Active Delta-9-THC, Active Ketamine
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Yale University
E-cigarette Use, Cigarette Smoking
BIDI Stick ENDS Abuse Liability and Puffing Topography Assessment
This study assessed the abuse liability (measured by assessing how much nicotine enters the body when the BIDI Stick is used, and how this makes users feel) and puffing topography (puff characteristics like volume and duration)…
- Trial name
- NCT05072925
- Testing
- Tobacco products
- Where
- Poland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- BIDI Vapor
Physical Activity, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Expanded Game Squad for Neurodiverse Youth
The proposed study will pilot the use of an adapted Game Squad intervention aimed at improving physical activity and other important health behaviors (nutrition, sleep hygiene, screen time habits) for children and adolescents…
- Conditions
- Physical Activity, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Health Behavior, Developmental Disorder
- Trial name
- NDGameSquad (NCT03665415)
- Testing
- NDGameSquad
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Merrimack College
Violence by Teachers
School-based Prevention of Teacher Violence Against Children in Zambia
The United Nations Conventions on the Rights of the Child UN General Assembly, 1989), outlawed violence against children worldwide.
- Trial name
- ICC-T Zambia (NCT07773961)
- Testing
- Interaction Competencies with Children
- Where
- Zambia
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Tobias Hecker, PhD
Depression, Mental Health Issue
Economic Evaluation of the MEWE Intervention
Cash transfers have shown promise in preventing intimate partner violence, and in reducing recipients' stress levels. Cash transfers with behavioral or psychological interventions have shown limited effectiveness at reducing…
- Conditions
- Depression, Mental Health Issue, Intimate Partner Violence, Domestic Violence
- Trial name
- MEWE-EE (NCT05598697)
- Testing
- Life Skills Building (LSB) curriculum for males, Life Skills Building (LSB) curriculum for females, Cash transfer to adult females
- Where
- Pakistan
- Volunteers
- 1,536 people, healthy volunteers welcome
- Sponsor
- London School of Economics and Political Science
Drug Abuse
General Well-being After Quitting Drug Use
The aim of this study is to investigate physical and physicosocial well-being after quitting drug use.
- Trial name
- NCT07641712
- Testing
- Physical well-being, Physico-social well-being
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University