Clinical trials: Acceptability
Pregnancy Prevention
Comparative Study of the Contraceptive Efficacy of the Cupid, Cupid 2 and FC2 Female Condom
This research study aims to assess the effectiveness of three female condoms [Cupid, Cupid 2 and Female Condom 2(FC2)] for the prevention of pregnancy among women choosing the female condom (FC) as their method of fertility…
- Trial name
- NCT04233632
- Testing
- FC2 Condom, Cupid Condom, Cupid 2 Condom
- Where
- South Africa
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Prof Mags Beksinska
Postnatal Complication
Family Led Postnatal Care in Ethiopia
Family-led Postnatal Care-FPNC A midwife involves families and uses a visual checklist to assess and counsel. The midwife then gives families the checklist along with information on how to retrieve a "homecare kit" that has a…
- Trial name
- FPNC (NCT05563974)
- Testing
- Family led postnatal care
- Where
- Ethiopia
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Jhpiego
HIV Infections, Chlamydia Trachomatis
Safety, Acceptability and Preliminary Effectiveness of Carraguard™ (PC-515) in Preventing HIV/STI Transmission
The primary aims of the study were to assess the safety and acceptability of Carraguard ™ (PC-515) when applied vaginally at least three times weekly for 6-12 months.
- Conditions
- HIV Infections, Chlamydia Trachomatis, Neisseria Gonorrhoeae, Trichomonas Vaginitis
- Trial name
- NCT00213018
- Testing
- Carraguard (PC-515)
- Where
- 2 sites in South Africa
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Population Council
Substance-related Disorders, Alcohol and Other Substance Use Prevention
Evaluating Feasibility, Acceptability, Usability, and an Initial Estimate of Effect of a Novel Training Platform on Peer Recovery Supporter Skill, Adherence, and Knowledge Gain-Phase I
This pilot study evaluates the feasibility, usability, and acceptability of the Thrive Digital Peer Platform (TDPP), an online training system for Peer Recovery Support Specialists (PRSS).
- Conditions
- Substance-related Disorders, Alcohol and Other Substance Use Prevention, Alcohol and Other Drug Use Disorders
- Trial name
- NCT07090590
- Testing
- Thrive Digital Peer Platform (TDPP)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Thrive Digital Health, LLC
Exoskeleton Device
Evaluation of Trunk Assistance Exoskeleton
The goal of this interventional study is to evaluate the effect of three different designs of trunk assistance exoskeletons on cumulative lumbar load, trunk extensors' muscular fatigue and comfort in healthy volunteers.
- Trial name
- NCT07084974
- Testing
- Adjustment and practice session, No trunk assistance, Uplift Lite exoskeleton
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- TOPMED
Solid Tumor, Solid Tumor, Adult
DESCANSO, a Mental Health Intervention for Depression, Insomnia, and Fatigue Symptoms in Latino People With Cancer
The purpose of this study is to improve ways of providing mental health support to Spanish-speaking Latino participants who have cancer and experience depression, insomnia, and fatigue.
- Trial name
- NCT07225088
- Testing
- DESCANSO/Depresión/Depressed Mood, Cansancio/Fatigue, and Sueño/Sleep; Rest in English
- Where
- 8 sites in United States, Puerto Rico
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Ponce Medical School Foundation, Inc.
Asthma Self Management
Use of Mobile Phone Application for Asthma Sele Management
This study aimed to assess the feasibility and acceptability of self-management provided through a mobile application.
- Trial name
- NCT06900361
- Where
- Malawi
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Kamuzu University of Health Sciences
HIV
IPREP Study #2: Evaluating Enhanced PrEP Packages for Young Female Sex Workers in Kisumu, Kenya
This is an open-label randomized controlled trial (n=200) in which HIV-negative young female sex workers (FSW) will be randomized to receive oral PrEP combined with specific behavioral and structural adherence interventions…
- Trial name
- NCT03988387
- Testing
- Peer Support (PS), Reminder and Resource Transfer (RRT), daily oral PrEP (emtricitabine 200 mg/tenofovir 300 mg) [FTC/TDF]
- Where
- Kenya
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Columbia University
Sexual Behavior, Depression
Our Family Our Future: Acceptability and Feasibility Study of a Family Prevention Program for HIV Risk and Depression
The purpose of this study is to assess the feasibility and acceptability of a family-based preventive intervention designed to reduce sexual risk behaviors and depressive symptoms among South African adolescents and their…
- Trial name
- NCT02432352
- Testing
- Our Family Our Future
- Where
- South Africa
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Brown University
Healthy
Exploring Adherence and Acceptability of an Intermittent Carbohydrate Restriction Regime in Free-Living Adults: A Feasibility Study
This study investigates a novel dietary approach called Intermittent Carbohydrate Restriction (ICR), which involves reducing carbohydrate intake on selected days of the week while allowing habitual eating on other days.
- Trial name
- NCT07056465
- Testing
- Intermittent Carbohydrate Restriction (ICR) Protocol
- Where
- United Kingdom
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Surrey
High Risk MSM, HIV Negative
Microbicide Safety and Acceptability in Young Men
After completing a screening evaluation, 280 eligible participants, including 40 sex workers, will be enrolled into Stage 1A of the study during which they will undergo a baseline medical evaluation for both history and presence…
- Conditions
- High Risk MSM, HIV Negative, 18-30 Years of Age
- Trial name
- Project Gel (NCT01283360)
- Testing
- Tenofovir 1% Gel
- Where
- 3 sites in United States, Puerto Rico
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- CONRAD
Contraception
Safety and Acceptability of Vaginal Rings That Protect Women From Unintended Pregnancy
The study is a multidisciplinary research project and has two main aims: 1. To determine the safety of a contraceptive vaginal ring (CVR) in women, with an emphasis on its effect on the vaginal microenvironment after different…
- Trial name
- Ring-Plus (NCT01796613)
- Testing
- Vaginal Ring - intermittent regimen, Vaginal Ring - continuous regimen
- Where
- Rwanda
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Intervention, Waitlist Control
Coach-Led Body Image Intervention for Girls in Sport - Pilot
According to the World Health Organization, only 15% of 11-17-year-old girls meet the recommended daily physical movement guidelines (e.g., 60-minutes per day).
- Trial name
- NCT05316610
- Testing
- Body Confident Athletes
- Where
- United Kingdom
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of the West of England
Contraception
An Intervention Delivered by App Instant Messaging to Increase the Acceptability of Effective Contraception Among Young People in Tajikistan
This randomised controlled trial will establish the effect a contraceptive intervention delivered by mobile phone app instant messaging on the acceptability of effective contraception in Tajikistan.
- Trial name
- NCT02905513
- Testing
- Contraceptive app instant messages, Mobile phone app
- Where
- Tajikistan
- Volunteers
- 580 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Body Image, Anti Fat Bias
The Evaluation of Two Positive Body Image Micro-interventions for Children Aged 4-6 Years
The goal of this 4-arm randomized controlled trial is to test the effectiveness of two positive body image media micro interventions (a tv show and a music video) in improving body image related constructs.
- Trial name
- NCT06146647
- Testing
- Positive body image TV show, Positive body image music video, Active control TV show about a visit to the dentist
- Where
- United Kingdom
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- University of the West of England
Feasibility, Safety and Tolerability of Device
A 6-month Study on the Feasibility, Safety, and Tolerability of a Silicone Myofunctional Infant Pacifier
The goal of this interventional feasibility study is to learn about the feasibility, acceptability, and safety of a novel myofunctional pacifier in infants from birth to 6 months of age.
- Trial name
- NCT07793058
- Testing
- BREATHE myofunctional pacifier
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Keystone OrthotropiX
Oily Skin
Evaluation of Dermal Acceptability and Comedogenic and Acnegenic Potential of a Cosmetic Product
This is a single-center, single-blind clinical study designed to evaluate the dermatological safety of a cosmetic product and to demonstrate the absence of comedogenic and acnegenic potential.
- Trial name
- NCT07768800
- Testing
- Blancy Pro
- Where
- Brazil
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Brainfarma Industria Química e Farmacêutica S/A
Childhood Cancer Survivor
Assessing the Acceptability of the Use of a Mobile Health App Among Young Adult Female Survivors of Childhood Cancer
The purpose of this research study is to understand if a mobile app is useful to assist young adult female survivors of childhood cancer in the self-management of survivorship-related needs.
- Trial name
- NCT03242200
- Testing
- Mobile Health App
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Adherence to Vaccination Schedules, Timeliness of Vaccination
SMS Mobile Technology to Improve Early Childhood Vaccine Coverage in Guatemala
This project plans to learn more about whether sending text messages to parents on their mobile phones to remind them when their child is due for his or her next vaccination will improve children getting vaccinated on time.
- Conditions
- Adherence to Vaccination Schedules, Timeliness of Vaccination, Acceptability of SMS Reminder Program
- Trial name
- SMSVaxGuate (NCT02567006)
- Testing
- SMS message, Usual care
- Where
- 2 sites in Guatemala
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Unemployment
Feasibility and Acceptability of the Online JOBS Program
The aim of this study is to test the feasibility and acceptability of a web-based adaptation of the Jobs program (developed by Curran et al., 1999).
- Trial name
- iJobs (NCT04885400)
- Testing
- iJobs
- Where
- Romania
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- West University of Timisoara