Clinical trials: Accidental Bowel Leakage
Bowel Incontinence
A Study to Evaluate the Safety, Tolerability and Effectiveness of the Renew Insert in Treating Accidental Bowel Leakage
The purpose of this study is to determine whether the use of the Renew Insert is effective, tolerable and safe in the treatment of accidental bowel leakage due to bowel incontinence.
- Trial name
- REST (NCT01475474)
- Testing
- Renew Insert
- Where
- 3 sites in United States
- Volunteers
- 97 people
- Sponsor
- Renew Medical
Fecal Incontinence
Clinical Study to Investigate the Effectiveness of the TOPAS System to Treat Fecal Incontinence
The purpose of this study is to demonstrate that the TOPAS System effectively treats fecal incontinence in women as measured by a 50% reduction in the number of FI episodes in a 14 day bowel diary at 12 months.
- Trial name
- TRANSFORM (NCT01090739)
- Testing
- TOPAS Treatment for Fecal Incontinence
- Where
- 14 sites in United States
- Volunteers
- 207 people
- Sponsor
- ASTORA Women's Health
Fecal Incontinence, Accidental Bowel Leakage
Effects of Eluxadoline (Viberzi®) 100 mg Twice Daily on Diarrhea-Associated Fecal Incontinence
Accidental bowel leakage (fecal incontinence) increases in people who have diarrhea and sensations of urgency to have a bowel movement.
- Conditions
- Fecal Incontinence, Accidental Bowel Leakage, Anal Incontinence, Diarrhea
- Trial name
- ELXDFI (NCT03489265)
- Testing
- Eluxadoline 100 mg
- Sponsor
- University of North Carolina, Chapel Hill
Fecal Incontinence, Bowel Incontinence
Neuromodulation for Accidental Bowel Leakage
This study is a multi-center, randomized clinical trial of women with refractory accidental bowel leakage (ABL) symptoms who have failed to achieve satisfactory symptom control from 2 first-line treatments for ABL: supervised…
- Trial name
- NOTABLe (NCT03278613)
- Testing
- ES-130
- Where
- 9 sites in United States
- Volunteers
- 166 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Fecal Incontinence
Implantation of BioSphincter TM for Treatment of Severe Passive Fecal Incontinence
This is first-in-human prospective Phase I study of the immediate and long-term safety of an implanted internal anal sphincter (IAS) bioengineered from autologous cells to treat subjects with severe passive FI who have failed…
- Trial name
- NCT05616208
- Testing
- Bioengineered Internal Anal Sphincter
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Cellf Bio LLC
Fecal Incontinence, Bowel Dysfunction
LIBERATE - PRO: Eclipse™ System Registry
A prospective, open label post market registry to collect Patient Reported Outcomes in an online data capture registry, maintained by Pelvalon, of women with fecal incontinence exiting the LIBERATE study (NCT02428595) continuing…
- Conditions
- Fecal Incontinence, Bowel Dysfunction, Bowel Incontinence, Accidental Bowel Leakage
- Trial name
- LIBERATEPRO (NCT03028636)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Pelvalon, Inc.
Accidental Bowel Leakage, Fecal Incontinence
Diet and Fecal Incontinence in Senior Women
Investigators will conduct a single-arm pre-post intervention pilot study in 46 older women with Fecal Incontinence (FI), also known as Accidental Bowel Leakage (ABL).
- Conditions
- Accidental Bowel Leakage, Fecal Incontinence, Incontinence, Bowel Incontinence
- Trial name
- NCT03510052
- Testing
- Diet Modification Pilot Program (DPM)
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Pennsylvania
Fecal Incontinence
Use of the LEVA® Pelvic Health System for Fecal Incontinence
The goal of this clinical trial is to learn about how the duration of use of The Leva Pelvic Health System® affects treatment of fecal incontinence in women.
- Trial name
- NCT06152224
- Testing
- The Leva Pelvic Health System
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Wisconsin, Madison
Fecal Incontinence, Bowel Incontinence
Fecal Incontinence Treatment (FIT) Study
Patients with severe fecal incontinence (FI), defined as two or more episodes of staining, solid or liquid FI per week, and who meet the inclusion criteria for Injection of Solesta (INJ; an inert bulking agent), or Biofeedback…
- Trial name
- NCT03811821
- Testing
- Biofeedback, Injection
- Where
- 6 sites in United States
- Volunteers
- 275 people
- Sponsor
- Mayo Clinic
Urinary Incontinence, Urge, Fecal Incontinence
Bladder Antimuscarinic Medication and Accidental Bowel Leakage
This observational research study will examine whether a medication known as darifenacin (Enablex ®) used for urgency urinary incontinence (UUI) also helps to improve fecal incontinence symptoms.
- Trial name
- BAMA (NCT03543566)
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Alabama at Birmingham
Urinary Incontinence, Fecal Incontinence
Pilot: Mind Over Matter: Healthy Bowels, Healthy Bladder
The study is to pilot-test an innovative, combined urinary/bowel continence workshop in two Wisconsin communities. Between 8-15 women with incontinence will be enrolled in each of the two pilot communities and will complete three…
- Conditions
- Urinary Incontinence, Fecal Incontinence, Accidental Bowel Leakage
- Trial name
- NCT02671747
- Testing
- Mind Over Matter; Healthy Bowels, Healthy Bladder
- Volunteers
- 56 people
- Sponsor
- University of Wisconsin, Madison
Fecal Incontinence
Effects of an Anal Insert Device in Fecal Incontinence
The purpose of this research is to test the effects of an inserted anal device on fecal incontinence (accidental bowel leakage) in patients who have persistent symptoms despite other conservative therapy.
- Trial name
- NCT03898778
- Testing
- Minnesota Medical Technologies Anal Insert Device
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Minnesota Medical Technologies