Clinical trials: Acute Aortic Syndrome
Aortic Aneurysm and Dissection
Clinical Health Outcomes Evaluation of Terumo Aortic Hybrid Devices
This prospective, non-interventional, study of Thoraflex Hybrid devices is part of Terumo Aortic's clinical development and Post Market Clinical Follow-Up (PMCF) plan and will provide insights into both the short- and long-term…
- Trial name
- CHEETAH (NCT07911163)
- Testing
- Thoraflex Hybrid
- Volunteers
- 150 people
- Sponsor
- Vascutek Ltd.
Thoracic Aortic Dissection
DISSECT-N Post Market Data Collection Registry
DISSECT-N is a post-market registry designed to assess real-world safety and effectiveness of Valiant Navion Thoracic Stent Graft System in the treatment of thoracic aortic dissections in real world practice.
- Trial name
- DISSECT-N (NCT04267055)
- Testing
- Valiant Navion Thoracic Stent Graft System
- Where
- 22 sites in United States, Denmark and 8 more
- Volunteers
- 102 people
- Sponsor
- Medtronic Cardiovascular
Aortic Aneurysm and Dissection
Guo's Endovascular Aortic Arch Replacement of Aortic Dissection by WeFlow-Tribranch Endoprothesis: a Multicenter Pilot Study(GRAFT Study)
To explore the effect and prognosis of endovascular interventional therapy in high-risk patients with aortic arch dissection and aneurysm
- Trial name
- NCT05754541
- Testing
- WeFlow-Tribranch Aortic Arch Stent Graft System
- Where
- 4 sites in China
- Volunteers
- 20 people
- Sponsor
- Hangzhou Endonom Medtech Co., Ltd.
Aortic Dissection
Safety and Efficacy Study Of The Thoracic Aortic Stent Graft System Treating Aortic Dissection
This is a prospective, multicenter and single-arm trail to study the safety and efficacy of the thoracic aortic stent graft system that specially designed for treating aortic dissection.
- Trial name
- NCT05430672
- Testing
- The Thoracic Aortic Stent Graft System (Zylox-Tonbridge Medical Technology Co., Ltd. )
- Where
- 14 sites in China
- Volunteers
- 120 people
- Sponsor
- Zhejiang Zylox Medical Device Co., Ltd.
Acute Myeloid Leukemia, Leukemia
A Phase I Study of AC220 in Patients With Relapsed/Refractory Acute Myeloid Leukemia Regardless of FLT3 Status
Patients received oral AC220 daily for 14 days to study the side effects, tolerability and best dose for treating relapsed or refractory acute myeloid leukemia, regardless of FLT3 status.
- Conditions
- Acute Myeloid Leukemia, Leukemia, Myelodysplastic Syndrome, AML
- Trial name
- NCT00462761
- Testing
- AC220
- Where
- 5 sites in United States, Georgia
- Volunteers
- 76 people
- Sponsor
- Daiichi Sankyo
Vascular Disease, Dissection
Long-term Characterization of GORE® TAG® Conformable Thoracic Stent Graft With ACTIVE CONTROL System Performance
An observational, prospective multi-regional post-market registry collecting mid- and long-term data to assess outcomes through ten years of follow-up for subjects treated with GORE® TAG® Conformable Thoracic Stent Graft with…
- Conditions
- Vascular Disease, Dissection, Dissection Aortic Aneurysm, Dissection of Aorta
- Trial name
- TGR 23-02TA (NCT06658730)
- Testing
- Endovascular
- Where
- 37 sites in United States, Denmark and 8 more
- Volunteers
- 1,500 people
- Sponsor
- W.L.Gore & Associates
Aortic Aneurysm, Aortic Dissection
Thoraflex™ Hybrid IDE Study
The study will assess the effectiveness, safety and clinical outcomes of the Thoraflex™ Hybrid Device in the treatment of aortic disease affecting the aortic arch and the descending thoracic aorta, with or without involvement of…
- Conditions
- Aortic Aneurysm, Aortic Dissection, Aortic Rupture
- Trial name
- NCT02724072
- Testing
- Thoraflex™ Hybrid Device
- Where
- 12 sites in United States
- Volunteers
- 84 people
- Sponsor
- Bolton Medical
Thoracic Diseases, Aortic Aneurysm
Thoraflex Hybrid and Relay Extension Post-Approval Study
The goal of this observational study is to evaluate the Thoraflex Hybrid device alone and in combination with the RelayPro NBS stent-graft in the treatment of aortic disease affecting the aortic arch and descending aorta with or…
- Conditions
- Thoracic Diseases, Aortic Aneurysm, Aortic Dissection, Thoracic Aortic Aneurysm
- Trial name
- EXTEND (NCT05639400)
- Testing
- Thoraflex Hybrid, RelayPro NBS
- Where
- 27 sites in United States, Austria and 5 more
- Volunteers
- 352 people
- Sponsor
- Vascutek Ltd.
Aortic Dissection Type B, Intramural Hematoma
CRATOS - Evaluation of Cratos™ Branch Stent Graft System in Treatment of Descending Aorta Lesions
The goal of this prospective, interventional, multicentre, single-arm performance objective study is to evaluate efficacy and safety of Cratos™ Branch Stent Graft System in treatment of lesions (dissection, IMH and PAU in…
- Conditions
- Aortic Dissection Type B, Intramural Hematoma, Penetrating Aortic Ulcer
- Trial name
- NCT05874206
- Testing
- Cratos™ Stent Graft
- Where
- Switzerland
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Shanghai MicroPort Endovascular MedTech（Group）Co., Ltd
Heart Failure, Cardiomyopathies
Multimodal Physiologic State Intelligence Study
The OMNIPHYS study will investigate whether multimodal ultrasound and other routinely collected clinical and physiologic data can be combined with artificial intelligence to characterize changes in a person's physiologic state…
- Conditions
- Heart Failure, Cardiomyopathies, Pulmonary Hypertension, Myocarditis; Acute or Subacute
- Trial name
- OMNIPHYS (NCT07814118)
- Testing
- OMNIPHYS Multimodal Ultrasound Imaging System
- Where
- United States
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Aortic Dissection
A Real-World Study on Distal Aortic Remodeling for Stanford Type B Aortic Dissection With Fabulous Thoracic Aortic Stent System
To evaluate aortic remodeling of Fabulous thoracic aortic stent system in the treatment of acute and subacute Stanford type B aortic dissection (the changes of aortic diameter, cross-sectional area,and volume of true lumen, false…
- Trial name
- NCT05883592
- Testing
- Fabulous Thoracic Aortic Stent System
- Where
- 2 sites in China
- Volunteers
- 50 people
- Sponsor
- Hangzhou Endonom Medtech Co., Ltd.