Clinical trials: Acute Asthma Exacerbation
Childhood Asthma With Acute Exacerbation
Comparison of Nebulizers vs Metered-Dose Inhalers With Spacer Device For Treatment Of Childhood Wheeze
The goal of this randomized controlled trial is to compare two different devices for the administration of the standard protocol drug.
- Trial name
- NCT06201156
- Testing
- Metered Dose Inhaler With Spacer Device
- Where
- Pakistan
- Volunteers
- 160 people
- Sponsor
- Khyber Teaching Hospital
Asthma
A Comparison of Combivent UDV (Ipratropium 500mcg and Salbutamol 2.5mg) and Salbutamol UDV Alone (2.5mg)
To compare the bronchodilator efficacy of ipratropium plus salbutamol (Combivent) with salbutamol alone given every 20 minutes for three doses in asthmatic children with severe acute exacerbation
- Trial name
- NCT00273962
- Testing
- ipratropium plus salbutamol UDV, salbutamol UDV
- Where
- 10 sites in Philippines
- Volunteers
- 500 people
- Sponsor
- Boehringer Ingelheim
Asthma
A Study of an Intravenous Drug in Pediatric Patients With Acute Asthma (0476-301)
This study will attempt to find out if the addition of an intravenous form of a drug that is already used for treating asthma in children will help resolve asthma attacks faster than using the current standard care alone.
- Trial name
- NCT00117338
- Testing
- montelukast sodium
- Volunteers
- 276 people
- Sponsor
- Organon and Co
Acute Asthma
A Pilot Study to Determine the Most Effective Dose of Arformoterol for Treating Acute Asthmatic Patients
The purpose of this study is to determine the best dose of nebulized arformoterol, a quick onset but long acting beta agonist, for use in treating acute bronchospasm in asthmatics presenting to the the Emergency Department.
- Trial name
- NCT00819637
- Testing
- arformoterol (RR formoterol), levalbuterol
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Henry Ford Health System
Acute Asthma
Feasibility of an ED Initiated Online Asthma Management Program for Urban Teens
The objective of this study is to determine the feasibility of conducting a randomized controlled trial to evaluate the effectiveness of an online, Emergency Department-initiated asthma management intervention designed to reduce…
- Trial name
- PuffCityED (NCT01695031)
- Testing
- Tailored asthma management program, Generic web-based education
- Where
- 2 sites in United States
- Volunteers
- 126 people
- Sponsor
- Henry Ford Health System
Pulmonary Disease, Chronic Obstructive
Etiology of Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD) in Japan
The purpose of this prospective, epidemiological, cohort study is to evaluate the lung microbiome in stable-state chronic obstructive pulmonary disease (COPD) in Japanese participants
- Trial name
- NCT03957577
- Testing
- Prospective observational cohort study
- Where
- 13 sites in Japan
- Volunteers
- 70 people
- Sponsor
- GlaxoSmithKline
Acute Asthma
Impact of Continuous Positive Airway Pressure on the Treatment of Acute Asthma Exacerbation
This current study aimed to demonstrate the effectiveness of the addition of CPAP to the current conventional therapy in terms of airway obstruction improvement in acute asthma patients.
- Trial name
- NCT01403467
- Testing
- Continuous positive airway pressure
- Where
- Thailand
- Volunteers
- 86 people
- Sponsor
- Ramathibodi Hospital
Acute Asthma, Dexamethasone
Dosing of Steroids for Acute Asthma Given in the Emergency Department - a Pilot Randomised Feasibility Trial of Dexamethasone in Children
Steroids given by mouth are an important first line treatment for children presenting with asthma attacks. Dexamethasone is the steroid used in some emergency departments (EDs) because of the need for a single dose and as it is…
- Trial name
- DOSAGE (NCT07402707)
- Testing
- dexamethasone oral
- Where
- United Kingdom
- Volunteers
- 104 people
- Sponsor
- Sheffield Children's NHS Foundation Trust
Asthma
Study of MK-0476 in Adult Patients With Acute Asthma (0476-334)
The study estimates the efficacy and safety of MK0476 and aminophylline intravenous administration in adult participants with acute asthma.
- Trial name
- NCT00442338
- Testing
- montelukast sodium, aminophylline hydrate
- Volunteers
- 91 people
- Sponsor
- Organon and Co
Acute Respiratory Infection, Asthma Exacerbations
Reusable Face Masks to Reduce Risk of Viral Respiratory Infections and Asthma Exacerbations
REMASK trial is a Trial within Cohort study (TwiCs), nested within the COVIDENCE UK longitudinal study. It has been designed to determine whether the offer of a free reusable, elastomeric face mask to adults with asthma and other…
- Trial name
- REMASK (NCT06885229)
- Testing
- FloMask - reuseable face mask
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Asthma, Mixed Asthma With Acute Exacerbation
Asthma Self-management Via Application of Telehealth
Objectives: The disease being studied is asthma. The main objective of this study is to assess the feasibility of the recruitment goals and also the logistical issues related to use of tele-health technology in developing…
- Trial name
- asthma (NCT02017795)
- Testing
- electronic asthma action plan (eAAP), written asthma action plan (WAAP)
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Asthma
Cessation Versus Continuation of Long-term Mepolizumab in Severe Eosinophilic Asthma Patients
Primary objective of the study is to evaluate whether patients with severe eosinophilic asthma who have received long-term treatment with mepolizumab (at least 3 years) need to maintain treatment with mepolizumab to continue to…
- Trial name
- NCT02555371
- Testing
- Mepolizumab 100mg
- Where
- 73 sites in United States, Argentina and 12 more
- Volunteers
- 306 people
- Sponsor
- GlaxoSmithKline
Asthma, Aged
Effects of Multidisciplinary Interventions in Elderly Asthma Patients With Risk of Acute Exacerbation
We want to examine the effect of multidisciplinary interventions in asthma patients who had experienced acute exacerbation of asthma.
- Trial name
- NCT01843439
- Testing
- Magnesium, Education for asthma action plan, hot-lines for acute exacerbation of asthma
- Where
- South Korea
- Volunteers
- 360 people
- Sponsor
- Sang-Heon Cho
Acute Exacerbation of COPD, Acute Exacerbation of Bronchiectasis
Outcomes of RV Dysfunction in Acute Exacerbation of Chronic Respiratory Diseases
Observational study in patients with chronic respiratory diseases (chronic obstructive pulmonary diseases, bronchiectasis, interstitial lung diseases, neuromuscular diseases, obesity-hypoventilation syndrome...) admitted in…
- Conditions
- Acute Exacerbation of COPD, Acute Exacerbation of Bronchiectasis, Acute Exacerbation of Asthma, Interstitial Lung Disease
- Trial name
- DVD (NCT04098094)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Asthma in Children
Cost Effectiveness Analysis of a Randomized Control Trial of q3h vs. q4h Albuterol as Discharge Criteria From the Hospital for Pediatric Asthma Exacerbations
Asthma is the most common chronic condition among children, and the third leading reason for hospitalization of children in the United States.
- Trial name
- NCT04542005
- Testing
- q3h albuterol
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Asthma
Oral Glucocorticosteroid in the Treatment of Severe Asthma Exacerbation in Hospitalized Patients
A comparison of oral prednisolone administration with intravenous methylprednisolone infusion in the treatment of acute asthma exacerbation in hospitalized patients.
- Trial name
- NCT00627731
- Testing
- methylprednisolone sodium succinate (mPSL), prednisolone (PSL)
- Where
- Japan
- Volunteers
- 50 people
- Sponsor
- Hamamatsu University
Asthma in Children
Scaling up the Integrated Care Pathway for Acute Asthma to All Osakidetza Pediatric Services Through a Cluster-randomized SMART Design
The main goal of this study is to evaluate the effectiveness of adaptive sequential implementation strategies based on facilitation in promoting the sustainable and widespread adoption and scaling up of the Integrated Care…
- Trial name
- NCT07642388
- Testing
- Internal + External Facilitation for Implementation, Internal + External Facilitation for Sustainability, Internal Facilitation
- Where
- Spain
- Volunteers
- 4,680 people
- Sponsor
- Basque Health Service
Asthma, Copd
Inhaler Trainer Efficacy Study
This will be a randomized, controlled, clinical trial. The investigators aim to determine the feasibility of and efficacy of the Inhaler Trainer Device for ongoing inhaler skill training.
- Conditions
- Asthma, Copd, Acute Exacerbation of COPD
- Trial name
- NCT06461403
- Testing
- Inhaler Trainer System, Initial Inhaler Use Assessment, Inhaler Use Instruction
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Koronis Biomedical Technologies
Asthma, COPD
Differentiation of Asthma/COPD Exacerbation and Stable State Using Automated Lung Sound Analysis With LungPass Device
This observational study evaluates whether lung sound analysis with LungPass device can be used to differentiate exacerbation and stable state asthma and COPD.
- Trial name
- NCT05145894
- Testing
- Lung auscultation with LungPass device (electronic auscultation)
- Where
- Belarus
- Volunteers
- 200 people
- Sponsor
- Healthy Networks
Allergic Asthma, Thunderstorm Asthma
Creating A Risk Assessment Tool for Thunderstorm Asthma: the CARISTA Study
Thunderstorm asthma is a recurring public health emergency in South-Eastern Australia which occurs in springtime. The major identified risk factors for thunderstorm asthma is hay fever and allergy to ryegrass pollen.
- Conditions
- Allergic Asthma, Thunderstorm Asthma, Seasonal Allergic Rhinitis, Grass Pollen Allergy
- Trial name
- CARISTA (NCT07055542)
- Testing
- Observational
- Where
- 6 sites in Australia
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- University of Melbourne