Clinical trials: Acute Back Pain
Low Back Pain
The Prognostic Value of Biomarkers and the Effect of Tolperisone in Acute Low Back Pain and Sciatic Pain "BETA"
The main purpose of the trial is to identify biomarkers from the blood as well as electrophysiologic and morphometric features (chemical, electrophysiologic and ultrasound biomarkers) that reflect the intensity of pain and/or…
- Trial name
- BETA (NCT05544656)
- Testing
- Tolperisone Hydrochloride
- Where
- Hungary
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Pain, Acute, Muscle Soreness
Analgesic Induces Similar Upper and Lower Body Pain Pressure Threshold Increases
Background: Both health professionals and consumers use menthol-based topical analgesics extensively for the temporary relief of pain from musculoskeletal ailments or injury.
- Conditions
- Pain, Acute, Muscle Soreness, Tendon Injuries
- Trial name
- NCT04677985
- Testing
- Menthol based topical analgesic
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Low Back Pain, Mechanical
Battlefield Acupuncture for Acute/Subacute Back Pain in the Emergency Department
The randomized controlled study aims was to investigate the pain control of Battle Field Acupuncture as Primary or Adjunctive Treatment in Back Pain (Acute Musculoskeletal pain) in the (acute pain setting) Emergency Department vs…
- Trial name
- NCT03996564
- Testing
- Battlefield Acupuncture, Acetaminophen, Diclofenac
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- San Antonio Military Medical Center
Acute Pain, Low Back Pain
Tactile Acuity in Experimentally Induced Acute Low Back Pain
The purpose of this study is to determine whether experimentally induced acute low back pain might lead to alteration in lumbar tactile acuity measured in region affected by pain compared to pain-free side and pain-free controls.
- Trial name
- NCT03021278
- Testing
- Saline injection
- Where
- Poland
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Acute Low Back Pain
The Palliative Effect of TENS-WAA on 'Capsaicin/Heat' Induced Acute Lower Back Pain: a Self-controlled Clinical Study
Acute lower back pain is a common condition that occurs in all age groups, and most people will experience acute lower back pain at least once in their lives.
- Trial name
- NCT06944665
- Testing
- Transcutaneous Electrical Nerve Stimulation based on Wrist-Ankle Acupuncture theory
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Xiaonan Huang
Chronic Back Pain
The Acute Effect Of Different Kinesiological Tape
This study aims to compare the acute effects of different kinesiology tapes on pain, functional performance and trunk endurance in young adults with chronic low back pain.
- Trial name
- NCT05167214
- Testing
- The Acute Effect Of Different Kinesiological Tape Application On Pain, Functional Performance And Trunk Endurance In Young Adults With Chronic Back Pain
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Baskent University
Osteoarthritis, Rheumatoid Arthritis
A Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetic Characteristics of DW1809-T2
Randomized, Open-label, Oral, Single-dose, two-Sequence, four-Period, crossover study
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Back Pain, Acute Upper Respiratory Tract Infection
- Trial name
- NCT05214690
- Testing
- DW1809-T2, DW1809-1
- Where
- South Korea
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Acute Back Injury
TENS Efficacy on Acute Back Pain in an Emergency Department Triage
Transcutaneous Electrical Nerve Stimulation (TENS) devices produce a gentle electrical stimulation that when applied through pads applied directly to the skin, has a noticeable effect in reducing pain associated with various…
- Trial name
- NCT03905681
- Testing
- Transcutaneous Electrical Nerve Stimulation
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- William Beaumont Army Medical Center
Disc Degenerative Disease, Spine Degeneration
Physiotherapy and Osteopathic Treatment for Pain in the Cervical and Lumbar Spine and Temporomandibular Joints
Study Summary: Effectiveness of Physiotherapy and Osteopathy in Treating Spinal and Temporomandibular Joint Pain About the Study and Its Objective This study is conducted by Artur Hołodniuk, MSc, a physiotherapist and academic…
- Conditions
- Disc Degenerative Disease, Spine Degeneration, Back Ache, Temporomandibular Disorder (TMD)
- Trial name
- NCT07830836
- Testing
- General Osteopathic Treatment, Visceral Therapy, Magnetic field therapy
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Low Back Pain, Inflammation
Acute Effects of High Intensity Training on Pain Processing and Inflammation in Chronic Low Back Pain.
A multitude of exercise therapy modalities are effective in improving daily physical function and relieving pain in various forms of chronic musculoskeletal pain (CMP) such as chronic neck pain, osteoarthritis, fibromyalgia, and…
- Trial name
- NCT04902196
- Testing
- high intensity cardiorespiratory exercise protocol, moderate intensity cardiorespiratory exercise protocol
- Where
- Belgium
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Pain, Head, Pain, Acute
Single-Dose Bioavailability Study of Two Formulations of Ibuprofen and Pseudoephedrine Hydrochloride Tablets
Evaluation of the comparative bioavailability between two oral formulations containing ibuprofen 200 mg and pseudoephedrine 30 mg after a single dose in healthy subjects under fasting conditions.
- Conditions
- Pain, Head, Pain, Acute, Pain, Back, Fever
- Trial name
- NCT03429738
- Testing
- Ibuprofen/Pseudoephedrine HCl 200/30 mg Film-Coated Tablets, RhinAdvil Rhume 200 mg/30 mg Film-Coated Tablets
- Where
- Canada
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Institut für Pharmakologie und Präventive Medizin
Anesthesia, Anesthesia, Local
Caudal Block Versus Dorsal Penile Nerve Block Plus Ring Block for Pain Management of Different Surgical Techniques of Circumcision in Infants and Children
Circumcision is one of the most commonly performed operations in the pediatric population and is a painful procedure. Circumcision is performed with two popular techniques, Plastibell and conventional dissection method (CDM).
- Conditions
- Anesthesia, Anesthesia, Local, Analgesia, Pediatric ALL
- Trial name
- NCT05233683
- Testing
- Caudal block, Dorsal penile nerve block plus ring block, Circumcision with Plastibell
- Where
- Saudi Arabia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- King Saud University
Chronic Low-back Pain
The Effect of an Acute Bout of Exercise on Pain Sensitivity and Clinical Pain in Adults With Chronic Low Back Pain
The goal of this interventional study is to investigate the efficacy of an acute bout of exercises on pain sensitivity (primary aim) and clinical pain intensity (secondary aim) among adults with Chronic Low Back Pain.
- Trial name
- NCT05779748
- Testing
- Single bout of exercise
- Where
- Saudi Arabia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Taif University
Low Back Pain
Characterizing the Role of Pain Sensitivity in Acute to Persistent Low Back Pain
This research study will examine whether enhanced pain sensitivity increases the risk of persistent low back pain. The study will address the highly prevalent and costly condition of persistent low back pain and a major obstacle…
- Trial name
- NCT01981382
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Acute Low Back Pain
Study to Evaluate a Pharmacokinetic Drug Interaction Between Eperisone Hydrochloride and Aceclofenac in Healthy Male Subjects
A randomized, open label, single-dose, 6-sequence, 3-period, crossover study to evaluate a pharmacokinetic drug interaction between eperisone hydrochloride and aceclofenac in healthy male subjects.
- Trial name
- NCT01638286
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hanmi Pharmaceutical Company Limited
Low Back Pain, Acute Pain
Magnesium Oral Supplementation for Acute Non-specific Low Back Pain
Acute non-specific low back pain (LBP) is one of the most common complaints at the emergency department. It is more prevalent in countries with high-income economies, where 60-80% of the population report back pain at some point…
- Trial name
- NCT04626063
- Testing
- Magnesium, NSAID, paracetamol
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Acute Low Back Pain
Efficacy and Safety of Fixed-dose Combination of Etoricoxib/Tramadol vs Acetaminophen/Tramadol for Acute Low Back Pain
Phase IIIb, longitudinal, multicenter, randomized, open-label clinical trial to evaluate the efficacy and safety of the fixed-dose combination of etoricoxib 90 mg and tramadol 50 mg compared with fixed-dose therapy of…
- Trial name
- NCT04968158
- Testing
- Etoricoxib 90 mg / Tramadol 50 mg, Acetaminophen 325 mg / Tramadol 37.5 mg
- Where
- Mexico
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Chronic Pain, Acute Pain
Assessing Symptom and Mood Dynamics in Pain Using the Smartphone Application SOMA
This study relies on the use of a smartphone application (SOMA) that the investigators developed for tracking daily mood, pain, and activity status in acute pain, chronic pain, and healthy controls over four months.The primary…
- Conditions
- Chronic Pain, Acute Pain, Post Operative Pain, Fibromyalgia, Primary
- Trial name
- NCT05754190
- Testing
- SOMA pain manager smartphone application
- Where
- United States
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Brown University
Chronic Pain
Can Therapy Alter CNS Processing of Chronic Pain: A Longitudinal Study
The purpose of this study is to investigate whether a psycho-therapeutic approach, group Cognitive Behavioral Therapy (CBT) plus a relapse prevention program, Therapeutic Interactive Voice Response (TIVR), modifies the…
- Trial name
- NCT01794988
- Testing
- Group Cognitive Behavioral Therapy, Pain Education, Therapeutic Interactive Voice Response
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Pain, Acute, Pain, Chronic
Changes in Affective Pain Processing in Human Volunteers
The experience of pain is more than the conscious perception of nociceptive signals. Emotional and motivational aspects accompany pain, leading to its aversiveness and motivation for avoidance.
- Conditions
- Pain, Acute, Pain, Chronic, Low Back Pain
- Trial name
- NCT04280796
- Testing
- psychophysical tasks, cognitive task
- Where
- Switzerland
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- susanne becker