Clinical trials: Acute Chest Pain
Postoperative Cognitive Dysfunction, Acute Postoperative Pain
Effect of TPVB on Postoperative Pain and Cognitive Function After VATS in Elderly Patients
To investigate the effect of ultrasound-guided thoracic paravertebral nerve block on postoperative acute and chronic pain and cognitive function in elderly patients with thoracoscopic partial lung resection.
- Conditions
- Postoperative Cognitive Dysfunction, Acute Postoperative Pain, Chronic Postsurgical Pain
- Trial name
- NCT05364216
- Testing
- Measurement of cognitive function, Thoracic paravertebral block, The assessment of cognitive function
- Where
- China
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Qinhuangdao
Post Operative Pain, Acute
A Comparative Study Between Ultrasound Guided Thoracic Paravertebral Block VS Serrartus Anterior Muscle Block in VATS as Regard Their Effectiveness in Post-operative Analgesia
A comparative study between ultrasound guided thoracic paravertebral block VS ultrasound guided serrartus anterior muscle block in video-assisted thoracoscopic surgeries as regard their effectiveness in post-operative analgesia
- Trial name
- NCT05971368
- Testing
- thoracic paravertebal block, serratus anterior muscle block
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pain, Acute, Congenital Heart Disease
Transverse Thoracic Plane Block in the Pediatric Cardiac Patient
Postoperative pain after cardiothoracic surgery can be a significant problem interfering with recovery, yet difficult to manage due to the sedating effects of opiates.
- Trial name
- TTPPCT (NCT04138745)
- Testing
- Transverse Thoracic Plane Block
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Ochsner Health System
Chest Pain, Acute Aortic Dissection
Prospective Multicenter Study for Early Evaluation of Acute Chest Pain
In this study, clinical database and blood sample bank of acute chest pain (ACP) will be established at chest pain center of multi-center hospital.
- Conditions
- Chest Pain, Acute Aortic Dissection, Pulmonary Embolism, Acute Myocardial Infarction Type 1
- Trial name
- PEACP (NCT04122573)
- Testing
- Coronary angiography, CT angiography of aorta, CT angiography of pulmonary arteries.
- Where
- 9 sites in China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Acute Coronary Syndrome Without ST Elevation on Electrocardiogram
Calibration Study PREDICT - Prehospital Triage for Suspected Acute Coronary Syndrome Without ST-segment Elevation
The PREDICT calibration study is a prospective, non-interventional trial aiming to adapt and calibrate the ACS-Pathfinder algorithm for prehospital triage of patients with suspected non-ST-elevation acute coronary syndrome…
- Trial name
- PREDICT (NCT07419139)
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- Leipzig Heart Science gGmbH
Acute Chest Syndrome
ST Elevation in Acute Chest Pain; Could Measurement of Lipoprotein-associated Phospholipase A2 (Lp-PLA2) be Helpful to the Clinician?
A blood test (2-3 cc peripheral venous blood) drawn /used from already available required lab tests to distinguish between pericarditis accompanied with electrocardiogram (ECG) signs mimicking infarction.
- Trial name
- NCT01041339
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alexhander Izhaki
Chest Pain, Acute Coronary Syndrome, Myocardial Infarction
Magnetocardiography in the Accurate Identification of Severe Coronary Lesions and Myocardial Necrosis
Magnetocardiography (MCG) is a promising noninvasive and accurate method for detecting myocardial ischemia. Although progress has been made in this area, there is a lack of studies using up-to-date examination instruments for the…
- Trial name
- NCT05392712
- Testing
- Magnetometer
- Where
- China
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Acute Coronary Syndrome, Myocardial Infarction (MI)
Clinical Echocardiography and S' Wave for Early Recognition of Acute Coronary Syndrome in the Emergency Department, A Prospective Study
The goal of this prospective observational study is to assess the diagnostic accuracy of the tissue Doppler imaging (TDI) S' wave in detecting acute coronary syndrome (ACS) in adult patients presenting to the emergency department…
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction (MI), Non-ST Elevation Myocardial Infarction, Unstable Angina
- Trial name
- CLEAR_ECHO (NCT06860997)
- Testing
- Tissue Doppler Imaging (TDI) S' Wave Echocardiography
- Where
- Belgium
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Coronary Syndrome, Acute, Non-ST Elevation, High Risk Patients
Management Tactics for Patients High Risk With Acute Coronary Syndrome Without ST Segment Elevation and Multivessel Coronary Artery Disease
The study will include patients with acute coronary syndrome without ST segment elevation and multivessel CA lesion, who are subject to surgical treatment according to KG data (Syntax Score 23 - 32 points with significant damage…
- Trial name
- NSTE-ACSMT (NCT06279663)
- Testing
- Revascularization
- Where
- 2 sites in Russia
- Volunteers
- 460 people, healthy volunteers welcome
- Sponsor
- Federal State Budgetary Institution National Medical Research Center named after academician E.N. Me
Myocardial Infarction, Chest Pain
Rapid Use of High-sensitive Cardiac Troponin I for ruling-in and Ruling-out of Acute Myocardial Infarction
Early rule-in or rule-out of myocardial infarction (MI) is essential in patients presenting to the Emergency Department with chest pain.
- Trial name
- RACING-MI (NCT03634384)
- Where
- Denmark
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Coronary Heart Disease, Acute Myocardial Infarction
Research on the Diagnostic Value of Machine Learning Model Based on Clinical Data in Patients With Coronary Heart Disease
Based on the clinical data of patients, a machine learning model for coronary heart disease diagnosis was established to evaluate whether the model could improve the accuracy of coronary heart disease diagnosis, and to evaluate…
- Conditions
- Coronary Heart Disease, Acute Myocardial Infarction, Angina
- Trial name
- NCT05018715
- Testing
- Machine learning model diagnosis
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Xiang Ma
Chest Pain, Acute Coronary Syndrome
Magnetocardiography in the Accurate Identification of Myocardial Infarction
Magnetocardiography (MCG) is a promising noninvasive and accurate method for detecting myocardial infarction. Although progress has been made in this area, there is a lack of studies using up-to-date examination instruments for…
- Conditions
- Chest Pain, Acute Coronary Syndrome, Myocardial Infarction
- Trial name
- NCT05896826
- Testing
- Magnetometer
- Where
- China
- Volunteers
- 3,841 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Emergency Medical Services, Nursing Care
High-Sensitivity Troponin I in Addition to Guideline-Based Care in EMS
The TIGER study is a study investigating the utlility of a point-of-care blood analyse of Troponin I to help identify patients with heart attacks in the prehospital emergency care.
- Conditions
- Emergency Medical Services, Nursing Care, Cardiology, Myocardial Infarction
- Trial name
- TIGER (NCT07008391)
- Testing
- high sensitivity Troponin I
- Where
- Sweden
- Volunteers
- 1,419 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Pain, Postoperative, Opioid Use
Analgesic Efficacy of Intravenous Ketamine as a Continuous Infusion vs PCA in the Management of Acute Postoperative Pain in Major Orthopedic Surgery.
The goal of this clinical trial is to determine whether treating pain after surgery with ketamine is more effective when administered intravenously as a continuous infusion or through a patient-controlled analgesia (PCA) pump.
- Conditions
- Pain, Postoperative, Opioid Use, Major Surgery
- Trial name
- NCT06774274
- Testing
- Ketamine infusion, PCA Ketamine
- Where
- Colombia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Acute Chest Pain
Coronary CT Angiography in Acute Chest Pain is a Cost Effective Risk Stratification Strategy
This study will evaluate the impact of adding coronary computed tomographic angiography (CTA) on health care costs for diagnosing patients with acute chest pain.
- Trial name
- NCT00825435
- Testing
- Coronary CT Angiogram
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Pain, Acute, Pain, Chest
Ultrasound-Guided Serratus and Transversus Thoracic Muscle Plane Block Vs. Erector Spinae Plane Block for Acute Poststernotomy Pain
Poststernotomy pain represents a complication that can arise following cardiac surgery. Inadequately managed pain has been linked to various adverse outcomes, including myocardial ischemia, cardiac arrhythmias, heightened…
- Trial name
- NCT06625580
- Testing
- transverse thoracic muscle plane and serratus anterior plane block, erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Acute Coronary Syndrome, Depression
MBCT Delivered Via Group Videoconferencing for ACS Patients With Elevated Depression Symptoms
The objective of this study is to identify Acute Coronary Syndromes (ACS) patients' specific needs and preferences for depression treatment via in-person or virtual individual interviews to (a) guide MBCT adaptation; and identify…
- Conditions
- Acute Coronary Syndrome, Depression, Myocardial Infarction, Unstable Angina
- Trial name
- NCT03878160
- Testing
- Individual Interview
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Pain, Postoperative, Pain, Acute
Pectoral Nerve Blocks (PECs) for Cardiovascular Implantable Electronic Device Placement
The purpose of this study is to determine whether administration of a pectoral nerve blocks (Pecs I and II) with 0.25% bupivacaine are more effective as compared to placebo to provide analgesia for cardiac implantable electronic…
- Conditions
- Pain, Postoperative, Pain, Acute, Pain, Chest, Pain
- Trial name
- NCT05283980
- Testing
- 0.25% Bupivacaine
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Heart Diseases, Cardiovascular Diseases
Risk Factors in the Initial Presentation of Specific Cardiovascular Disease Syndromes
Cardiovascular disease (CVD) is an important public health problem that affects millions of people worldwide. Associations between risk factors, such as smoking, dyslipidaemia or hypertension, and prevalent CVD are well…
- Conditions
- Heart Diseases, Cardiovascular Diseases, Acute Myocardial Infarction, Unstable Angina
- Trial name
- NCT01804439
- Volunteers
- 2,240,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Abdominal Aortic Aneurysm, Acute Myocardial Infarction
Body Mass Index and Initial Presentations of Cardiovascular Diseases
The association between obesity and cardiovascular disease (CVD) has mostly been studied using broad endpoints or have focused on cause-specific mortality.
- Conditions
- Abdominal Aortic Aneurysm, Acute Myocardial Infarction, Stroke, Heart Failure
- Trial name
- CALIBER (NCT01704300)
- Where
- United Kingdom
- Volunteers
- 2,240,000 people, healthy volunteers welcome
- Sponsor
- University College, London