Clinical trials: Acute Conditions
Cervical Pain
Instrument-assisted Soft Tissue Mobilization and Kinesiotape Application in Individuals With Chronic Neck Pain.
Chronic neck pain causes errors in joint position sense. There are studies in the literature suggesting that instrument-assisted soft tissue mobilization and Kinesiotape applications improve the joint position sense.
- Trial name
- NCT04765670
- Testing
- Instrument Assisted Soft Tissue Mobilization, Kinesiotape Application
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Ventilatory Defect, COVID-19
Visualizing Regional Lung Ventilation in Patients With Postacute-COVID-19
There is a lack of data of spontaneous breathing patients with post-COVID-19 syndrome (PCS) examined by Electrical impedance tomography (EIT). We compare 100 patients with PCS with 50 healthy probands.
- Conditions
- Ventilatory Defect, COVID-19, Post-acute COVID-19 Syndrome, Electric Impedance Tomography
- Trial name
- ViReVentPoCov (NCT05441657)
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Jan-Christoph Lewejohann
Acute Pain
Self-Compassion and Acute Pain
Research on self-compassion suggests its impact in the context of pain. In the current study, the investigators evaluate a short self-compassion intervention for coping with acute pain.
- Trial name
- NCT03647683
- Testing
- Self-Compassion, Acceptance, Distraction
- Where
- Germany
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Philipps University Marburg
Acute Postoperative Pain
Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Profile of HYR-PB21 in Healthy Volunteers
This study is the first time into human study (FTIH) for HYR-PB21 for injection. The study will evaluate the safety, pharmacokinetics (PK) and pharmacodynamics (PD) of single ascending and single subcutaneous dose of HYR-PB21 for…
- Trial name
- NCT04169256
- Testing
- HYR-PB21, Liposomal bupivacaine, Normal Saline
- Where
- Australia
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Fruithy Medical Pty Ltd
Sarcopenia, Functional Decline
Impact of Acute Hospitalisation and Resistance Training on Muscle Architecture and Physical Performance in Older Adults
Sarcopenia characterised by loss of muscle mass, muscle strength and physical performance burdens many older adults since the condition is related to functional decline.
- Conditions
- Sarcopenia, Functional Decline, Muscle Architecture, Gait Speed
- Trial name
- NCT05798169
- Testing
- Resistance training
- Where
- Denmark
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Hypoxia, Exercise Performance
Acetazolamide and Exercise Performance at Altitude
The goals of the present study are to evaluate whether the most common, and effective, treatment for acute mountain sickness (AMS), acetazolamide (AZ), has a negative, positive, or no influence on exercise performance, cognitive…
- Conditions
- Hypoxia, Exercise Performance, Cognitive Function, Dexterity
- Trial name
- NCT03525561
- Testing
- Acetazolamide Pill
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- United States Army Research Institute of Environmental Medicine
Acute Lymphoblastic Leukemia ALL
Study of Cell-free DNA in Children and Adolescents With Acute Lymphoblastic Leukemia
Minimal residual disease (MRD) monitoring is a key prognostic factor in pediatric acute lymphoblastic leukemia (ALL). Currently, MRD assessment relies mainly on cellular DNA obtained from bone marrow aspirates.
- Trial name
- CIRCALL (NCT07483476)
- Testing
- Biological sample collection
- Where
- 2 sites in France
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Survival, Prosthesis, Oxygen Deficiency
Awake Prone Positioning for COVID-19 Acute Hypoxaemic Respiratory Failure
The objective of our study is to evaluate the effectiveness of prone position in preventing intubation or death in spontaneously ventilated patients with COVID-19 with acute respiratory failure.
- Trial name
- NCT05866289
- Testing
- Prone position
- Where
- Morocco
- Volunteers
- 1,069 people, healthy volunteers welcome
- Sponsor
- Mohammed VI University Hospital
Asthma, Copd
Inhaler Trainer Efficacy Study
This will be a randomized, controlled, clinical trial. The investigators aim to determine the feasibility of and efficacy of the Inhaler Trainer Device for ongoing inhaler skill training.
- Conditions
- Asthma, Copd, Acute Exacerbation of COPD
- Trial name
- NCT06461403
- Testing
- Inhaler Trainer System, Initial Inhaler Use Assessment, Inhaler Use Instruction
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Koronis Biomedical Technologies
Acute Pain
Sub-dissociative Dose Ketamine Dosing Study
Goal is to determine if in adults presenting to the Emergency Department (ED) with moderate to severe acute pain, Ketamine administered at 0.15 mg/kg will provide similar pain relief to Ketamine administered at 0.3 mg/kg, with…
- Trial name
- NCT03714620
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Loyola University
Acute Coronary Syndrome, Chest Pain
Standardizing Emergency Work-ups Around Risk Data
Chest pain is the second leading reason for emergency department (ED) visits in the United States. Resource utilization for this ED subpopulation is particularly high, in part due to a dearth of accepted standardized clinical…
- Conditions
- Acute Coronary Syndrome, Chest Pain, Risk Reduction
- Trial name
- STEWARD (NCT03286179)
- Testing
- modified HEART score and/or Emergency Department Assessment of Chest pain Risk Score (EDACS)
- Where
- 12 sites in United States
- Volunteers
- 13,419 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Pain, Post-operative
Multimodal Analgesic Protocol to Moderate Acute Pain
With a prospective, observational study assess post-surgery pain levels and patient's use of opioids and other analgesic drugs to moderate pain following third molar surgery.
- Trial name
- NCT03456141
- Testing
- third molar surgery
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Chronic Obstructive Pulmonary Disease
Oral Supplement and Acute Resistance Exercise
This study should provide the mechanistic basis for and evaluation of a new nutritional formulation to be used alongside exercise training to improve muscle function and exercise performance by minimizing exercise induced…
- Trial name
- HMB exercise (NCT06801951)
- Testing
- acute resistance exercise with oral nutrition supplementation, stable tracer infusion
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Type 2 Diabetes
Exercise, Glucose Kinetics, and the Incretin Effect
Human volunteers will be stratified by oral glucose tolerance status: normal glucose tolerant, impaired glucose tolerant, and type 2 diabetic.
- Trial name
- NCT01607931
- Testing
- Exercise
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Emergencies
Optimized Acute Care for Geriatric Patients Using an Intersectoral Telemedical Cooperation Network - Around the Clock - Technical Performance
Due to "demographic change", the composition of the population in Germany is changing. The consequence of this change is a population that is getting older on average.
- Trial name
- Optimal@NRW (NCT04873973)
- Testing
- Telemedical support
- Where
- Germany
- Volunteers
- 3,073 people, healthy volunteers welcome
- Sponsor
- RWTH Aachen University
Headache
Olanzapine for Acute Headaches
This trial is a prospective, randomized, feasibility trial with the primary aim of comparing how well oral rapidly dissolving olanzapine controls primary headache pain when compared to the current treatment strategies used in…
- Trial name
- Olanzapine (NCT03066622)
- Testing
- Standard of Care as per attending physician, 5mg rapidly dissolving olanzapine
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Pain, Orthognathic Surgery
Effect of Nefopam on Acute Postoperative Pain in Patients Undergoing Orthognathic Surgery
The aim of this study is to determine the analgesic effect of perioperative nefopam on acute pain in patient undergoing orthognathic surgery.
- Trial name
- NCT01461031
- Testing
- nefopam, normal saline (control)
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Catholic University of Korea
Diarrhea, Respiratory Infection
Micronutrient Sprinkles in a Daycare Center
Diarrheal diseases are a major cause of morbidity and mortality globally in children less than 5 years of age. Prolonged diarrhea, recurrent infections and growth failure in developing countries are usually a consequence of…
- Trial name
- NCT00967551
- Testing
- Micronutrient Sprinkles with zinc, Micronutrient sprinkles without zinc
- Where
- Brazil
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Emory University
Insulin Resistance, Impaired Glucose Tolerance
Cassia Cinnamon for Glucose Uptake in Young Women
The purpose of this study was to compare the acute effects of 5g of Cassia cinnamon, 50 minutes of endurance exercise performed at 70% of the heart rate reserve (correlated to VO2max), and 5g of cellulose placebo on blood…
- Conditions
- Insulin Resistance, Impaired Glucose Tolerance, Prediabetes
- Trial name
- NCT00951639
- Testing
- Cassia cinnamon, 50 minutes exercise, Cellulose Powder
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Baylor University
Hepatic Failure, Liver Failure
Cardiox Liver Function Test Pivotal Trial
Performance evaluation of LFT Dye Monitor System using ICG - plasma disappearance rate value (PDR) to assess liver function in normal patients as well as in patients with mild to severe hepatic impairment compared to manual Serum…
- Trial name
- LFT-0002 (NCT02552901)
- Testing
- 0.1 mg/kg ICG Dose, 0.5 mg/kg ICG dose
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Cardiox Corporation
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