Clinical trials: Acute Coronary Disease
Acute Decompensated Heart Failure
Registry (Prospective Cohort) for Heart Failure in Korea (KorAHF)
KorAHF is a multi-center registry (prospective cohort) for acute decompensated heart failure patients in Korea. The aim of this registry is to analyze several causes affecting prognosis and survival and to develop new strategies…
- Trial name
- KorAHF (NCT01389843)
- Where
- South Korea
- Volunteers
- 5,625 people
- Sponsor
- Byung-Hee Oh
Heart Valve Diseases
Prolonged Cardiopulmonary Bypass Time as a Predictive Factor for AGI After Heart Valve Replacement
In this retrospective study, the investigators will analyze the correlation between cardiopulmonary bypass (CPB) time and acute gastrointestinal injury (AGI), and the outcomes of AGI in patients undergoing heart valve replacement.
- Trial name
- NCT05498935
- Testing
- CPB time
- Where
- China
- Volunteers
- 1,070 people
- Sponsor
- Hepatopancreatobiliary Surgery Institute of Gansu Province
Ventricular Fibrillation, Ventricular Tachycardia
Further Acute Research of a Subcutaneous Implantable Defibrillator (S-ICD) System
The purpose is to further evaluate the operation, safety, and feasibility of a subcutaneous implantable defibrillator (S-ICD) system in patients who require an implantable cardioverter defibrillator (ICD)for treating ventricular…
- Trial name
- NCT00399217
- Testing
- Subcutaneous Implantable Defibrillator (S-ICD) system, ICD
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- Boston Scientific Corporation
Acute Myocardial Infarction
Effects of Nitric Oxide for Inhalation in Myocardial Infarction Size
The purpose of this study is to determine the effects of Nitric Oxide for Inhalation on Myocardial Infarction Size.
- Trial name
- NOMI (NCT01398384)
- Testing
- Nitric Oxide, MI size at 48-72 hours
- Where
- 4 sites in Belgium, Hungary and 1 more
- Volunteers
- 250 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
SCI - Spinal Cord Injury
Cardiocentric Inotropic Optimization in Spinal Cord Injury
The first hours-to-day following acute traumatic cervical SCI represent a critical period of time to optimize hemodynamic management. After a spinal cord injury, cardiovascular function is affected.
- Trial name
- CARDIO-SCI (NCT07871643)
- Testing
- Dobutamine crossover
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- University of British Columbia
ST-segment Elevation Myocardial Infarction (STEMI)
PRasugrEl Monotherapy Following prImary percUtaneous Coronary Intervention for ST-elevation Myocardial Infarction
The aim of this study is to evaluate the safety of prasugrel monotherapy without aspirin versus 12-month dual antiplatelet therapy (DAPT) in patients with STEMI using platinum-chrome everolimus-eluting stent (PtCr-EES: SYNERGYTM).
- Trial name
- PREMIUM (NCT05709626)
- Testing
- No aspirin (Prasugurel monotherapy), 12-month DAPT
- Where
- Japan
- Volunteers
- 2,258 people
- Sponsor
- Kindai University
Sepsis, Septic Shock
Nucleosome Monitoring Relevance for Outcome Prediction in Critically Ill Patients
NUROPI is a single-centre, prospective, non-interventional study in the Intensive Care Unit (ICU) of Erasme Hospital (Hôpital Universitaire de Bruxelles, Brussels, Belgium).
- Conditions
- Sepsis, Septic Shock, Cardiac Arrest (CA), Pancreatitis
- Trial name
- NuROPI (NCT07184593)
- Testing
- Plasma H3.1 nucleosome measurement
- Volunteers
- 1,000 people
- Sponsor
- Erasme University Hospital
ST-segment Elevation Myocardial Infarction (STEMI)
Effect and Safety of Fexofenadine Hydrochloride vs Placebo in Patients With Acute Myocardial Infaction: A Randomized Clinical Trial
The purpose of this study was to evaluate the efficacy and safety of fexofenadine hydrochloride on the basis of standard treatment after PCI in STEMI patients.
- Trial name
- FEND-AMI (NCT06548204)
- Testing
- Fexofenadine Hydrochloride
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Acute Coronary Syndrome
Low-dose Ticagrelor in Chinese ACS Patients Undergoing PCI
Dual Antiplatelet Therapy (DAPT) with aspirin and P2Y12 receptor inhibitor remains a cornerstone in the secondary prevention of coronary artery disease (CAD).
- Trial name
- NCT03381755
- Testing
- half-dose ticagrelor, standard-dose ticagrelor
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Acute Renal Insufficiency, Acute Coronary Syndrome
Acute Renal Insufficiency (ARI) Rate and Predictive Score of ARI in Hospitalized Patients for Acute Coronary Syndrome With ST-segment Elevation Needing Urgent Coronarography
The primary objective of the study aims to evaluate frequence of acute renal insufficiency in patients with ST-segment elevation who need urgent coronary angiography in Ambroise Paré hospital.
- Trial name
- COROAKI (NCT04481126)
- Where
- France
- Volunteers
- 168 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Kidney Injury, IHD
The Effect of Spironolactone on Acute Kidney Injury in Patients Undergoing Coronary Angiography
an interventional study to measure the possible effects of spironolactone ( an aldosterone antagonist) on the incidence of acute kidney injury after coronary angiography
- Conditions
- Acute Kidney Injury, IHD, Contrast-induced Nephropathy
- Trial name
- NCT03329443
- Testing
- Spironolactone
- Where
- Iraq
- Volunteers
- 490 people
- Sponsor
- Alhasan Mujtaba Abdul-Wahid
Mild Therapeutic Hypothermia, Cardiogenic Shock
Effect of Mild Therapeutic Hypothermia on the Doses of Vasopressors and Inotropes in Cardiogenic Shock Complicating Acute Myocardial Infarction
The study aimed to assess the effects of mild therapeutic hypothermia (MTH) on vasopressors and inotropes in patients with cardiogenic shock (CS) due to acute myocardial infarction (AMI).
- Conditions
- Mild Therapeutic Hypothermia, Cardiogenic Shock, Acute Myocardial Infarction, Vasopressors
- Trial name
- NCT06947616
- Testing
- Mild therapeutic hypothermia
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Angina, Unstable
Diagnosis and Treatment of ACS in the ED: The Impact of Rapid Bedside cTnI Testing on Outcomes
In a randomized, controlled clinical trial, point-of care testing at the bedside using the cardiac biomarker troponin I in ED patients with possible ACS will be compared to traditional testing of this assay for myocardial…
- Trial name
- Dispo-ACS (NCT00222352)
- Testing
- Point of Care cTnL testing
- Where
- 4 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- University of Cincinnati
Left Ventricular Dysfunction
Bone Marrow Derived Mononuclear Cells For Myocardial Regeneration
Evaluative pilot study for safety and feasibility with administration of autologous bone bone marrow derived mononuclear cells by endoventricular catheter into the normal border zone fo the ischemic lesion.
- Trial name
- NCT00938847
- Testing
- PCI
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- Asklepios proresearch
Risk Stratification
Predicting Ventricular Tachyarrhythmias Following Acute ST Elevation Myocardial Infarction
Predict-VT is an investigator-initiated, prospective, observational clinical trial. Four hundred patients with ST elevation acute myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI) will be…
- Trial name
- PREDICT-VT (NCT03263949)
- Testing
- Diagnostic
- Where
- Serbia
- Volunteers
- 400 people
- Sponsor
- Clinical Centre of Serbia
Inferior Wall; Transmural Myocardial Infarction, Right Ventricular Dysfunction
Acute Right Ventricular Infarction Registry
This Study aims to provide an assessment of clinical presentation, management, hospital course, and prognosis of acute right ventricular infarction presenting with or without Inferior or infero-posterior wall Myocardial…
- Trial name
- NCT06424028
- Testing
- Right Ventricular Infarct
- Where
- Pakistan
- Volunteers
- 1,000 people
- Sponsor
- National Institute of Cardiovascular Diseases, Pakistan
Acute Coronary Syndrome
99th Percentile Upper Reference Limit (URL) for the Meritas Troponin I Test
Prospective multicenter sample collection and testing study.
- Trial name
- NCT02638311
- Where
- 3 sites in United States
- Volunteers
- 769 people, healthy volunteers welcome
- Sponsor
- Trinity Biotech
Surgery--Complications, Abdomen Disease
Use of Wearables for Early Detection of Complications After Major Acute Abdominal Surgery
The purpose of the study is to investigate whether glucose profile, sleep disturbances and heart rate variability measured with wearable devices is associated with postoperative recovery and complications within 30 days after…
- Trial name
- NCT04257344
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Zealand University Hospital
Acute Coronary Syndrome, STEMI
The Effect of Colchicine on Inflammation in ACS Patients
This study will evaluate whether the anti-inflammatory effect of colchicine is beneficial in ACS patients
- Trial name
- NCT06054100
- Testing
- Colchicine Tablets
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Ain Shams University
Myocarditis Acute
MCE Molecular Imaging for Myocarditis
Inflammation of the heart (myocarditis) is a serious condition that can cause heart failure, abnormal heart rhythms, cardiac arrest, and death. Rapid diagnosis of this condition is key to reversing it.
- Trial name
- NCT07538544
- Testing
- Myocardial contrast echocardiography molecular imaging for inflammation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Virginia
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