Clinical trials: Acute GVHD
Aortic Dissection, Family Research
Study on Susceptibility Genes and Pathogenic Mechanism of Non-syndromic Familial Aortic Dissection
Aortic dissection is dangerous and difficult to predict, so it is particularly important to carry out early prevention, diagnosis and rational treatment for high-risk groups.
- Conditions
- Aortic Dissection, Family Research, Aortic Dissection, Familial, With or Without Aortic Aneurysm
- Trial name
- NCT04439565
- Testing
- movement
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chinese Medical Association
Transgender Persons
Transgender Observational Performance
The study will evaluate the sports capabilities of transgender women mainly in terms of muscular strength and aerobic capacity (VO2max).
- Trial name
- TOP (NCT05337865)
- Testing
- Aerobic exercise test.
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Instituto Brasileiro de Controle do Cancer
B-Cell Acute Lymphoblastic Leukaemia
Blinatumomab Consolidation in Real World
This will be a multi-center registry for patients with B-ALL. Patient data will be collected both retrospectively and prospectively.
- Trial name
- NCT07117136
- Where
- 5 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Recovery Methods, Exercise Training
Effects of Different Recovery Methods on Lactic Acid Removal, Flexibility, Strength, and Endurance
The aim of this study is to compare these three different recovery methods following a single bout high-intensity interval exercise program with each other in terms of blood lactate clearance, muscle flexibility, muscle strength…
- Trial name
- NCT03563430
- Testing
- Active Recovery Group, Self-Massage with Foam Roller Group, Neuromuscular Electrical Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Biruni University
Pneumonia, Acute Respiratory Disease
Effectiveness of the Pneumococcal Polysaccharide Vaccine in Military Recruits
The primary objective is to determine the clinical benefit of employing the 23-valent pneumococcal vaccine among US military trainees. Secondary objectives include: determining the etiology of clinical pneumonia among U.S.
- Trial name
- NCT02079701
- Testing
- 23-valent pneumococcal vaccine
- Where
- 5 sites in United States
- Volunteers
- 152,723 people, healthy volunteers welcome
- Sponsor
- Naval Health Research Center
SARS-CoV Infection
A Feasibility Study Using the CoronaCheck Device to Identify Incident Cases of SARS CoV-2 Covid-19
Point of care testing is urgently required to enable the immediate detection of SARS-CoV-2 infection to allow effective transmission prevention precautions to succeed.
- Trial name
- NCT04742712
- Testing
- CoronaCheck Device
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Portsmouth Hospitals NHS Trust
Interstitial Lung Disease, Chronic Thromboembolic Pulmonary Hypertension
129Xe MRI Cardiopulmonary
The goal of this NIH-sponsored study is to characterize three biomarkers derived from 129Xe gas exchange MRI and to understand how they change in response to interventions.
- Conditions
- Interstitial Lung Disease, Chronic Thromboembolic Pulmonary Hypertension, Acute Pulmonary Embolism, Anemia
- Trial name
- NCT06038630
- Testing
- Hyperpolarized Xe129, Oxygen Administration
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Bastiaan Driehuys
Injury;Sports
Acute Effect of Motor-Cognitive Training
Participants will complete a functional MRI to evaluate brain activation, functional connectivity, and behavioral performance immediately before and after a training program (approximately 30 minutes).
- Trial name
- NCT06017154
- Testing
- Motor-Cognitive Training Program
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Ke'La H Porter
Malnutrition; Protein, Protein Malnutrition
Increase Protein Intake of Older Meal Service Clients With Readymade Protein-rich Meals and Foods
Rationale: Undernutrition risk among community-dwelling older adults in developed countries is shown to be around 24%. Increasing protein intake is a strategy that is feasible as well as efficacious to reduce undernutrition in…
- Trial name
- ConsuMEER (NCT03032237)
- Testing
- Nutritional intervention - protein-rich, Nutritional intervention - standard
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- HAN University of Applied Sciences
Pain, Acute, Edema
Lornoxicam Versus Etodolac After Third Molar Surgery
Our study aimed to compare the effect of lornoxicam and etodolac on postoperative pain, edema and trismus following lower third molar extraction
- Conditions
- Pain, Acute, Edema, Trismus
- Trial name
- NCT05679453
- Testing
- Lornoxicam 8 Mg Oral Tablet
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Gastroenteritis
Bivalent Norovirus Vaccine Study
Randomized, multi-site, dose-escalation study of the safety and immunogenicity of four dosage levels of Intramuscular (IM) Norovirus Bivalent VLP Vaccine adjuvanted with MPL and Al(OH)3 compared to controls.
- Trial name
- NCT01168401
- Testing
- NoV GI.1/GII.4 Bivalent VLP Vaccine, Saline
- Where
- 3 sites in United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Takeda
Oral Glucose Tolerance
Coffee Roasting and Glucose Tolerance
Chlorogenic acid (CGA) in coffee may lower the postprandial glucose response. CGA is destroyed by dark roasting. In a controlled crossover trial, 11 healthy fasted volunteers consumed 300 mL of either light (LIR) or dark (DAR)…
- Trial name
- NCT02417519
- Testing
- DAR, LIR, CTR
- Where
- Denmark
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Acute Cholecystitis
Acute Cholecystitis: Early Versus Delayed Laparoscopic Cholecystectomy; Randomized Prospective Study
The best management of the acute cholecystitis is to do laparoscopic cholecystectomy. The hypothesis is that to do it as an early intervention after patient admission is better than delayed cholecystectomy regarding the hospital…
- Trial name
- NCT02130245
- Testing
- Early cholecystectomy, Delayed cholecystectomy
- Where
- Egypt
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Sleep, Emotion
The Effects of Acute vs. Chronic of Screen Illumination on: Sleep Efficacy and Architecture, Physiology, Emotion and Behavior: Possible Effect on Human Health
The human eye has a dual role, which is reflected by the various photo-receptors used for vision of images and colors ,Image forming photoreceptors (IFP) and for entrainment of our "Biological clock" located in the hypothalamus…
- Trial name
- NCT02839395
- Testing
- No intervention- base line, Acute, Chronic
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Assuta Medical Center
Cannabis User
Effect of Acute Exercise on Cognitive Functions and Blood Markers of Brain Plasticity in Regular Chronic Cannabis Users
The endocannabinoid system (ECS) is a complex endogenous signaling system made up of transmembrane cannabinoid receptors (CB1 and CB2 receptors), their endogenous lipid-derived ligands (the endocannabinoids - eCBs), and enzymes…
- Trial name
- CANNABEX (NCT06081218)
- Testing
- activity test
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Acute Ischemic Stroke
COOLing of the Ischemic PENumbra in Patients With Acute Ischemic Stroke.
This study will develop and validate a novel, active/conductive combined head and neck cooling system to selectively cool the ischemic penumbra during the acute phase of stroke, reducing neuronal damage and improving stroke…
- Trial name
- PEN-Cool (NCT07844096)
- Testing
- PEN-Cool Conductive Head-and-Neck Cooling System, Standard Reperfusion Therapy / Routine Care
- Where
- 5 sites in India
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Christian Medical College and Hospital, Ludhiana, India
Stability, Posturography
Acute Effects of Elastic Band Resistance on Postural Stability and Physical Function in Older Adults
Current balance and stability interventions have been shown to improve balance through targeting balance impairments and retraining effects.
- Conditions
- Stability, Posturography, Balance, Old Age; Debility
- Trial name
- NCT05224362
- Testing
- A repeated measures acute study using using elastic resistance bands in older adults to challenge stability.
- Where
- 2 sites in United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Derby
Healthy Young Men
Effect of Acute Grape Seed Extract Supplementation on the Heart Rate Recovery in Young Individuals
This study hypothesized that sustained sympathoexcitation via MMA slows down PHRR and that GSE supplementation is effective at improving PHRR in young individuals.
- Trial name
- NCT07137988
- Testing
- 600 mg grape seed extract, 600 mg Starch
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- California Baptist University
Anesthesia, Opioid Use
Opioid-Free Anesthetic for Tonsillectomy
Prospective randomized controlled trial to determine if opioid-free anesthetic for tonsillectomy is non-inferior to standard opioid-containing anesthetic
- Conditions
- Anesthesia, Opioid Use, Tonsillitis, Sleep Disorder
- Trial name
- NCT04528173
- Testing
- Ketorolac, Dexmedetomidine, Morphine
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Sarcopenia, Functional Decline
Impact of Acute Hospitalisation and Resistance Training on Muscle Architecture and Physical Performance in Older Adults
Sarcopenia characterised by loss of muscle mass, muscle strength and physical performance burdens many older adults since the condition is related to functional decline.
- Conditions
- Sarcopenia, Functional Decline, Muscle Architecture, Gait Speed
- Trial name
- NCT05798169
- Testing
- Resistance training
- Where
- Denmark
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
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