Clinical trials: Acute Herpes Zoster
Pain, Neuropathic
Stellate Ganglion Block in Herpes Zoster
Patient who will be presented to Tanta University Hospitals complaining of acute herpes zoster with onset of vesicular eruption less than 7 days will be included in this clinical study.
- Trial name
- NCT04188327
- Testing
- Stellate ganglion block
- Where
- 3 sites in Egypt
- Volunteers
- 208 people
- Sponsor
- Tanta University
Herpes Zoster (HZ)
Multimodal Nerve Block and Pulse Radiofrequency for Acute Herpes Zoster Pain
The primary objective of this clinical trial is to evaluate the efficacy of liposomal bupivacaine and ropivacaine in the treatment of pain associated with herpes zoster (shingles).
- Trial name
- NCT06798662
- Testing
- Ultrasound-Guided Pulsed Radiofrequency (PRF), Intercostal nerve block (2% ropivacaine or 133 mg of liposomal bupivacaine), Paravertebral (PVB) Block (2% ropivacaine or 133 mg of liposomal bupivacaine)
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xiaguang Duan
Herpes Zoster, Neuralgia, Postherpetic
Subcutaneous Lidocaine Injection in Acute Herpes Zoster Neuralgia and Post-herpetic Neuralgia
In this study, it was aimed to compare the effect of subcutaneous lidocaine injection, which is routinely applied in pain clinic,in patients who present with pain complaints due to acute herpes zoster and post-herpetic neuralgia…
- Trial name
- SCL-HZ/PHN (NCT06882525)
- Testing
- Lidocaine (drug)
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Ankara City Hospital Bilkent
Zoster Without Complications
Regional Anesthesia to Relief Zoster Pain
Pain in Herpes is a serious issue for patients. at the acute phase it is a moderate to severe pain . 30% patients will develop a post herpetic neuralgia this percentage up to 70 % after 60 years old.
- Trial name
- NCT04133142
- Testing
- peripheral nerve block, inter fascial nerve block
- Where
- Vietnam
- Sponsor
- Vinmec Healthcare System
Herpes Zoster
Efficacy of Pregabalin for the Treatment of Acute Herpetic Neuralgia
All eligible Herpes Zoster patients will be randomized into two groups. Group 1 will be the treatment group receiving Pregabalin 75 mg twice daily for 4 weeks in addition to other routine treatment.
- Trial name
- NCT03809702
- Testing
- Pregabalin
- Where
- Nepal
- Volunteers
- 82 people
- Sponsor
- B.P. Koirala Institute of Health Sciences
Acute Pain in Herpes Zoster
NPC-06 to Acute Pain in Herpes Zoster
The purpose of this trial is to investigate the efficiency of pain relief and the safety of NPC-06 for the acute pain in herpes zoster in the placebo-controlled double-blind parallel group trial, in addition to explore the…
- Trial name
- NCT04139330
- Testing
- NPC-06
- Where
- Japan
- Volunteers
- 16 people
- Sponsor
- Nobelpharma
Herpes Zoster, Local Infiltration
Clinical Efficacy and Safety of Tender Point Infiltration (TPI) for Acute and Subacute Zoster Associated Pain
Herpes zoster (HZ) is a skin infection disease which cause severe zoster-associated pain (ZAP) along sensory nerve in the corresponding segment.
- Conditions
- Herpes Zoster, Local Infiltration, Acute Pain
- Trial name
- NCT06344403
- Testing
- analgesic, Tender point infiltration
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Beijing Tiantan Hospital
Herpes Zoster, Zoster-Associated Pain
Efficacy and Safety of High-Concentration 35 kDa Hyaluronan Gel for Herpes Zoster-Associated Pain
This is a prospective, single-arm, open-label, pilot clinical study to evaluate the efficacy and safety of topical 10% high-concentration 35 kDa hyaluronan (HA35) gel in subjects with herpes zoster-associated pain (ZAP).
- Conditions
- Herpes Zoster, Zoster-Associated Pain, Postherpetic Neuralgia, Neuropathic Pain
- Trial name
- HA35-HZ (NCT07569978)
- Testing
- 10% High-Concentration 35 kDa Hyaluronan (HA35) Topical Analgesic Gel
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Nakhia Impex LLC
Herpes Zoster
Occlusion vs Standard Treatment for the Treatment of Herpes Zoster
This study evaluates the addition of occlusive dressings (hydrocolloids) or topical silicone gel in the treatment of shingles (herpes zoster).
- Trial name
- NCT04258930
- Testing
- Aluminum sulphate and calcium acetate drying soaks, Topical sterile silicone gel for wounds, Hydrocolloid dressing
- Where
- Mexico
- Volunteers
- 36 people
- Sponsor
- Fundación Nacional para la Enseñanza y la Investigación de la Dermatología A.C.
Neuropathic Pain
Vitamin C as add-on Therapy in Patients With Acute Herpes Zoster
To compare the efficacy and tolerability of three different doses of Pascorbin® besides standard medication with placebo and the reduction of herpes zoster-associated clinical symptoms as an add-on therapy for patients suffering…
- Trial name
- NCT05561257
- Testing
- Vitamin C
- Where
- 3 sites in Germany
- Volunteers
- 12 people
- Sponsor
- Pascoe Pharmazeutische Praeparate GmbH
Acute Lymphoblastic Leukemia, Pediatric
Vaccine Immune Recovery After Leukemia
This observational study aims to assess recovery of the immune system and immunity to vaccine-preventable diseases in children, adolescents, and young adults who recently completed treatment for acute lymphoblastic leukemia…
- Trial name
- VIRAL (NCT05622682)
- Testing
- Observational only: Serology and flow cytometry for ALL cohort participants, Observational only: Infection rates
- Where
- 6 sites in United States
- Volunteers
- 89 people
- Sponsor
- Children's Hospital of Philadelphia
Treatment of PHN
3VM1001 Cream for the Treatment of Pain Associated With Post Herpetic Neuralgia (PHN)
Post-herpetic neuralgia (PHN) is pain following acute herpes zoster; defined as pain lasting longer than 3 months. Current first line management consists of tricyclic anti-depressants and anti-convulsants such as gabapentin and…
- Trial name
- PHN (NCT03421613)
- Testing
- 3VM1001
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- CDA Research Group, Inc.
Acute Herpes Zoster Neuropathy
Ultrasound Guided Serratus Anterior Versus Erector Spinae Block in Pain Alleviation in Acute Herpes Zoster
Acute herpes zoster pain is very severe . Conventional analgesics may be of no value. Regional blocks may play a role
- Trial name
- NCT06476080
- Testing
- ultrasound guided erector spine block, Serratus anterior block
- Volunteers
- 120 people
- Sponsor
- Minia University
RENAL INSUFFICIENCY, CHRONIC, LIVER FAILURE, ACUTE
Safety and Efficacy of ProQuad® in Children 6-24 Month Being Evaluated for Solid Organ Transplant
A prospective, multisite study to evaluate the Impact of Measles, Mumps, Rubella and Varicella ProQuad® vaccination in pediatric patients 6-24 months of age who are being considered and/or evaluated for any solid organ transplant…
- Conditions
- RENAL INSUFFICIENCY, CHRONIC, LIVER FAILURE, ACUTE, HEART DISEASE
- Trial name
- ProQuad® (NCT02687763)
- Testing
- ProQuad
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Medical University of South Carolina
Herpes Zoster, Pain
The Analgesic Efficacy and Safety of Venlafaxine for Prevention of Postherpetic Neuralgia in Patients With Acute Herpes Zoster
Postherpetic neuralgia (PHN) is the most common complication of herpes zoster (HZ) and represents a major clinical challenge due to its chronicity and impact on quality of life.
- Conditions
- Herpes Zoster, Pain, Postherpetic Neuralgia
- Trial name
- NCT07361796
- Testing
- Venlafaxine combined conventional therapy, Conventional therapy
- Where
- China
- Volunteers
- 832 people
- Sponsor
- Beijing Tiantan Hospital
Herpes Zoster
Esketamine Combined With PRF of DRG for Acute/Subacute Zoster-associated Pain
To assess the 1-month effects and safety of esketamine - PRF -standardized drug treatment against PRF -standardized drug treatment acute/subacute zoster-associated pain (ZAP) patients.
- Trial name
- NCT06914206
- Testing
- esketamine group, PRF group
- Where
- China
- Volunteers
- 184 people
- Sponsor
- Beijing Tiantan Hospital
Acute Herpes Zoster
A Study Investigating the Pharmacokinetics of FV-100 With and Without Ritonavir in Healthy Volunteers
This study is designed to evaluate the potential for a PK drug-drug interaction between FV-100 and ritonavir. The study is a single-center, open-label, randomized, 2-way crossover design in healthy volunteers.
- Trial name
- NCT02322957
- Testing
- FV-100
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- ContraVir Pharmaceuticals, Inc.
Herpes Zoster
A Phase 2b Trial of EPB-348 for the Treatment of Herpes Zoster
The purpose of this study is to determine the pharmacokinetics and dosage of EPB-348 that best balances safety and efficacy among adult immunocompetent patients with an acute episode of herpes zoster.
- Trial name
- NCT00831103
- Testing
- EPB-348, Valacyclovir
- Where
- United States
- Volunteers
- 373 people
- Sponsor
- Epiphany Biosciences
Acute Herpes Zoster
Efficacy of Electroacupuncture for Acute Herpes Zoster-Associated Pain and Biomarker Evaluation
Background: Herpes zoster (HZ) is an acute dermatological condition caused by the varicella-zoster virus. Its onset is characterized by severe pain, imposing significant physical and psychological burdens on patients.
- Trial name
- NCT07515885
- Testing
- Acupuncture, Valacyclovir, pregabalin and mecobalamin
- Where
- China
- Volunteers
- 228 people
- Sponsor
- Dexiong Han
Alopecia Areata, Depressive Episode
The Epidemiology, Management, and the Associated Burden of Related Conditions in Alopecia Areata
This study series consists of four related studies and aims to explore and describe many important elements of alopecia areata over three key areas: (1) the current epidemiology of alopecia areata, (2) the prevalence and…
- Conditions
- Alopecia Areata, Depressive Episode, Recurrent Depressive Disorder, Anxiety Disorders
- Trial name
- NCT04239521
- Testing
- Exposure of interest (studies 2 & 3).
- Where
- United Kingdom
- Volunteers
- 51,955 people
- Sponsor
- Momentum Data