Clinical trials: Acute Ischemic Stroke Patients
Stroke, Stroke, Acute
Gut Microbiota in Acute Stroke Patients
This study is to find out the significance of gut-microbiota in acute stroke patients, including their neurological, radiological outcomes as well as their stroke mechanisms.
- Conditions
- Stroke, Stroke, Acute, Stroke, Ischemic, Microbiome
- Trial name
- NCT03934021
- Where
- Hong Kong
- Volunteers
- 120 people
- Sponsor
- Chinese University of Hong Kong
Brain Infarction
Continuous Positive Airway Pressure Ventilation After Acute Ischemic Stroke
More than half of all stroke patients have sleep apneas in the acute phase after stroke. Sleep apneas may be associated with higher degrees of disability three months after stroke due to numerous factors associated with sleep…
- Trial name
- NCT00151177
- Testing
- non-invasive continuous positive airway pressure ventilation, CPAP-treatment
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University Hospital Muenster
Stroke
Augmenting Cerebral Blood Flow in Acute Ischemic Stroke
The most common type of stroke is ischemic (lack of blood flow to the brain due to a clot blocking a blood vessel). Time is brain and an average of 1.9 million brain nerve cells per minute are destroyed in patients experiencing a…
- Trial name
- NCT06911385
- Testing
- Arm Remote Ischemic Conditioning plus Pneumatic Compression lower limb
- Volunteers
- 150 people
- Sponsor
- University of Alberta
Stroke, Acute, Blood Pressure
Central and Peripheral Blood Pressure in Stroke
Individuals who experience a stroke or transient ischaemic attack (TIA) are at heightened risk of subsequent vascular events, including heart attacks and secondary stroke/TIA.
- Trial name
- NCT02537652
- Testing
- Blood pressure assessment
- Where
- 2 sites in United Kingdom
- Volunteers
- 29 people
- Sponsor
- Hampshire Hospitals NHS Foundation Trust
Infarction, Middle Cerebral Artery, Infarction, Anterior Cerebral Artery
Effect of Mesenchymal Stem Cells(MSCs) Transplantation for Acute Cerebral Infarction Patients
This is a placebo controlled, randomized, double blinded study including Phase 1 and Phase 2. Phase I study is a safety assessment and Phase 2 study is incline to assess effectiveness of MSCs.
- Conditions
- Infarction, Middle Cerebral Artery, Infarction, Anterior Cerebral Artery, Cerebral Infarction, Stroke, Ischemic
- Trial name
- NCT04093336
- Testing
- human umbilical cord mesenchymal stem cells, standardized treatment
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai East Hospital
Acute Ischemic Stroke
Prospective, Multicentre Study to Evaluate the Thrombectomy System for Stroke: iNedit, iNdeep and iNtercept
First prospective, single-arm, multicentre study to evaluate the safety and efficacy of the overall stroke thrombectomy system: iNedit, iNdeep and iNtercept in patients with acute ischemic stroke.
- Trial name
- SEMTiC (NCT05893719)
- Testing
- iNedit, iNdeep, iNtercept
- Where
- 18 sites in Belgium, Germany and 1 more
- Volunteers
- 175 people
- Sponsor
- iVascular S.L.U.
Acute Coronary Syndrome, Myocardial Infarction
What is the Optimal Antithrombotic Strategy in Patients With Atrial Fibrillation Undergoing PCI?
The optimal antithrombotic management in patients with coronary artery disease (CAD) and concomitant atrial fibrillation (AF) is unknown.
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Atrial Fibrillation, Atrial Flutter
- Trial name
- WOEST-3 (NCT04436978)
- Testing
- 30-day DAPT, Guideline-directed therapy
- Where
- 20 sites in Belgium, Netherlands
- Volunteers
- 2,000 people
- Sponsor
- St. Antonius Hospital
Acute Ischemic Stroke
Anesthesia Technique and Outcomes in Mechanical Thrombectomy for Acute Ischemic Stroke
This retrospective cohort study examined clinical outcomes in patients who underwent mechanical thrombectomy for acute ischemic stroke under general anesthesia or sedoanalgesia.
- Trial name
- NCT07422649
- Testing
- General Anesthesia, Sedoanalgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 481 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Acute Ischemic Stroke Patients
Evaluation of rSO2 Between Frontal Lesion Area and Normal Area of Brain by NIRSITX Using NIRS in Acute Ischemic Stroke Patients.
The clinical trial is for acute ischemic stroke patients measuring cerebral oxygen saturation (rSO2) values using pulse oximeter of near-infrared spectroscopy in the frontal lesion area and normal area of brain.
- Trial name
- fNIRS (NCT06250608)
- Testing
- Pulse oximeter, NIRSITX
- Where
- 2 sites in South Korea
- Volunteers
- 35 people
- Sponsor
- OBELAB, Inc.
Ischemic Stroke
Efficacy of High and Low-Dose Simvastatin on Vascular Oxidative Stress and Neurological Outcome in Patients With AIS
Patients with acute ischemic stroke will be divided into 2 groups by double-blind, randomized, and controlled trial. Personality and past history of the patients will be recorded after the patients signed inform consent.
- Trial name
- NCT03402204
- Testing
- Simvastatin 10 mg, Simvastatin 40 mg
- Volunteers
- 64 people
- Sponsor
- Thammasat University
Brain Disease, Ischemic Attack, Transient
Natural History of Stroke: Cause and Development
The purpose of this study is to learn more about stroke and obtain information that may serve as the basis for future investigations.
- Conditions
- Brain Disease, Ischemic Attack, Transient, Cerebrovascular Accident, Cerebrovascular Disorder
- Trial name
- NCT00009243
- Where
- 3 sites in United States
- Volunteers
- 4,000 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke, Acute Ischemic Stroke
Repinotan in Patients With Acute Ischemic Stroke
The purpose of this trial is to evaluate Repinotan HCl in patients with acute ischemic stroke. At study entry patients will be randomized to Repinotan HCl or placebo in a 1:1 ratio. The total treatment period wil be 72 hours.
- Trial name
- NCT00044915
- Testing
- Repinotan HCl (BAYX3702)
- Where
- 119 sites in United States, Australia and 13 more
- Volunteers
- 782 people
- Sponsor
- Bayer
Ischemic Stroke, Acute
Innovative Technologies in Restoring Gait and Balance Funtions in Ischemic Stroke Patients at the Inpatient Stage
The scientific hypothesis was based on data on the effectiveness of the usage of robotic mechanotherapy and virtual reality technologies.
- Trial name
- NCT05423626
- Testing
- technologies of robotic mechanotherapy with FES, biofeedback virtual reality technologies
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- Moscow Scientific and Practical Center of Medical Rehabilitation, Restorative and Sports Medicine
Ischemic Stroke, Neurological Injury
Omega 3 and Ischemic Stroke; Fish Oil as an Option
In this trial, The investigators are going to investigate the improvement of neurological functions and infarced area of the brain in ischemic stroke patients after ingestion of omega 3 products that have high concentrations of…
- Conditions
- Ischemic Stroke, Neurological Injury, Stroke, Acute, Inflammatory Response
- Trial name
- OmegaStroke (NCT04386525)
- Testing
- Omega-3 fish oil
- Volunteers
- 60 people
- Sponsor
- King Fahad Medical City
Stroke, Acute, Stroke, Ischemic
Observational Study of Efficiency of Cytoflavin, in Patients With Ischemic Stroke Not Receiving Reperfusion Therapy
Stroke remains one of the main socially significant problems in the healthcare in the third millennium. The lethality in persons with history of stroke by the end of the 1st year of disease is high.
- Trial name
- NCT06514976
- Testing
- Cytoflavin
- Where
- 17 sites in Russia
- Volunteers
- 562 people
- Sponsor
- POLYSAN Scientific & Technological Pharmaceutical Company
Stroke, Ischemic
Prognostic Factors and Mortality in Older Stroke Patients With Mechanical Thrombectomy
The study focus on the elderly patient (older than 80 years of age) who had acute ischemic stroke and received mechanical thrombectomy.
- Trial name
- NCT04672148
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- Far Eastern Memorial Hospital
Ischemic Stroke, TIA
Apixaban Versus Dual-antiplatelet Therapy (Clopidogrel and Aspirin) in Acute Non-disabling Cerebrovascular Events
Nondisabling cerebrovascular events represent the largest group of cerebrovascular disease with a high risk of recurrent stroke.
- Trial name
- ADANCE (NCT01924325)
- Testing
- Apixaban, Clopidogrel, Aspirin
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Xijing Hospital
Correction of Cancer-related Coagulopathy With Novel Oral Anticoagulant (Edoxaban)
Edoxaban for the Treatment of Coagulopathy in Patients With Active Cancer and Acute Ischemic Stroke: a Pilot Study. (ENCHASE Study)
Purpose: Cancer-related hypercoagulability plays an important role in the development of cancer-related stroke. With rapidly aging population and increasing cancer prevalence, cancer related stroke has become an important stroke…
- Trial name
- ENCHASE (NCT03570281)
- Testing
- Edoxaban, Enoxaparin
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Samsung Medical Center
Ischemic Stroke
Registry for Evaluating Outcome of Acute Ischemic Stroke Patients Treated With Mechanical Thrombectomy.
The Bernese-European RegistrY for ischemic stroke patients treated Outside current guidelines with Neurothrombectomy Devices using the SOLITAIRE™ FR With the Intention For Thrombectomy (BEYOND-SWIFT) is a retrospective…
- Trial name
- BEYOND-SWIFT (NCT03496064)
- Testing
- Successful reperfusion
- Where
- Switzerland
- Volunteers
- 2,000 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Ischemic Stroke, Depression
Dose Milnacipran Prevent Depressive Symptoms in Patients With Acute Stroke?
Depression is one of the important psychiatric sequelae after stroke. The prevalence of post stroke depression (PSD) is approximately 20-40%.
- Trial name
- NCT00606203
- Testing
- milnacipran
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Chang Gung Memorial Hospital