Clinical trials: Acute Low Back Pain
Acute Low Back Pain (Low Back Pain for Less Than 3 Months)
Preventing the Transition From Acute to Persistent Disabling Low Back Pain Through Cognitive Functional Therapy
Acute low back pain often resolves spontaneously, but some patients develop persistent pain and disability. The goal of this clinical trial is to determine whether Cognitive Functional Therapy (CFT), compared with usual care, can…
- Trial name
- FIN-BACK (NCT07877454)
- Testing
- Cognitive Functional Therapy (CFT), Usual Care
- Where
- Finland
- Volunteers
- 461 people
- Sponsor
- University of Oulu
Sub-acute Non-specific Low Back Pain
Low Load Blood Flow Restriction Training Versus Traditional Heavy Load Resistance Training in Male Athletes With Sub-acute Non-specific Low Back Pain
his randomized clinical trial aims to compare the effects of low-load blood flow restriction (LL-BFR) training and traditional heavy-load resistance training (HL-RT) on male athletes with sub-acute non-specific low back pain.
- Trial name
- NCT07480759
- Testing
- Low Load Blood Flow Restriction Training (LL-BFR), Traditional Heavy Load Resistance Training (HL-RT)
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- University of Lahore
Back Pain, Muscle Pain
Transcutaneous Electrical Nerve Stimulation for Back Pain in the Emergency Department (TENS-ED)
The effectiveness of Transcutaneous Electrical Nerve Stimulation (TENS) to reduce pain scores for patients with acute back pain in an ambulatory emergency department (ED) population will be examined in this dual-center, cluster…
- Conditions
- Back Pain, Muscle Pain, Acute Pain, Lower Back Pain
- Trial name
- TENS-ED (NCT05601843)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Sam Brophy
Low Back Pain
Effect of the Hands- on McKenzie Program on Low Back Pain
Low back pain (LBP) is one of most prevalent types of musculoskeletal pain and is strongly related to disability. The McKenzie method is one of most popular treatment options for LBP.
- Trial name
- NCT03066674
- Testing
- McKenzie group, Control group
- Volunteers
- 38 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Non-specific Low Back Pain (NSLBP)
Erector Spinae Plane Block for Acute Low Back Pain
Non-Specific low back pain (NSLB) is an important public health problem with a major economic and social impact. It is defined by the location of pain, between the lower rib margins and the lumbar vertebrae.
- Trial name
- ESP-BACK (NCT07434024)
- Testing
- Erector Spinae Plane Block with isotonic saline, Erector Spinae Plane Block with local anesthetic
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
Low Back Pain
Efficacy of Metamizole Versus Ibuprofen and a Short Educational Intervention Versus Standard Care in Acute Low Back Pain
The EMISI trial is a randomized, double blind, controlled trial (RCT) using a factorial design in patients with a new low back pain episode.
- Trial name
- EMISI (NCT04111315)
- Testing
- Metamizole Sodium, Ibuprofen 600 mg, Patient education
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Back Pain, Acute Pain
Tolperisone in Acute Muscle Spasm of the Back
This is a double-blind, randomized, placebo-controlled, parallel group study of the efficacy and safety of tolperisone (a non-opioid) or placebo administered as multiple doses three times a day (TID) in approximately 400 male and…
- Conditions
- Back Pain, Acute Pain, Back Spasm Upper Back, Back Strain
- Trial name
- STAR (NCT03802565)
- Testing
- Tolperisone
- Where
- 43 sites in United States
- Volunteers
- 415 people
- Sponsor
- Neurana Pharmaceuticals, Inc.
Acute Low Back Pain
A Study to Evaluate the Efficacy and Safety of Fixed Dose Combination of DW340 in Patients With Acute Low Back Pain
A Single-Center, Randomized, Double-Blind, Parallel, Pilot Study to Evaluate the Efficacy and Safety of Fixed Dose Combination of Pelubiprofen/Eperisone in Patients with Acute Low Back Pain
- Trial name
- NCT03424707
- Testing
- DW340(pelubiprofen/eperisone), Pelubi(pelubiprofen)
- Volunteers
- 45 people
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Benign Gynecological Disease
Predicting Acute Postoperative Pain by the Preoperative Lower Back Pain
To investigate if the level of preoperative lower back pain has the effect on the acute postoperative pain after gynecological laparoscopy
- Trial name
- NCT04793191
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- The Catholic University of Korea
Low Back Pain
Effectiveness of Transcutaneous Electrical Nerve Stimulation in Patients With Acute Low Back Pain
Introduction: Low back pain is one of the most common complaints in doctors' offices, and acute low back pain is characterized by episodes of pain with less than three weeks duration.
- Trial name
- NCT02427425
- Testing
- TENS
- Volunteers
- 71 people
- Sponsor
- Federal University of São Paulo
Low Back Pain
The Acute Effect of Kinesio Tape on Pain, Joint Range of Motion and Dynamic Balance in Patients With Low Back Pain
The aim of this study is to evaluate the acute effect of kinesio taping on pain, range of motion and dynamic balance in patients with chronic nonspecific low back pain.
- Trial name
- NCT06749821
- Testing
- Kinesio Tape, Control (no last irrigation)
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Istanbul Saglik Bilimleri University
Neck Pain, Low Back Pain
Study to Demonstrate That Muscle Pattern Recognition (MPR) is an Effective Evaluation Tool for Musculoskeletal Neck or Back Pain
The investigators hypothesize that non able-bodied participants with reported acute, sub-acute, or chronic symptoms of neck or back pain of a musculoskeletal origin will have magnetic resonance imaging (MRI), X-ray and blood…
- Trial name
- NCT00134225
- Testing
- Muscle Pattern Recognition (MPR)
- Where
- 4 sites in United States, Canada
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- iTech Medical, Inc.
Low Back Pain
Morphine Versus Morphine-promethazine Combination for Acute Low Back Pain Relief in the Adult Emergency Department
Acute low back pain is a common cause for emergency department visits. Controversy remains regarding the optimal medication for acute low back pain relief.
- Trial name
- NCT01129934
- Testing
- Morphine-Promethazine, morphine
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Preventive Medicine
Preventing Chronicity of Sub-acute Low Back Pain by Altering the Neural Emotional Response to Pain
Aim of the study It could be stated that chronification of low back pain in some respects depends on the emotional reactions to the acute pain state.
- Trial name
- NCT05450263
- Testing
- Interoceptive exposure
- Where
- Finland
- Sponsor
- Orton Orthopaedic Hospital
Acute Low Back Pain
A Randomized Study of Three Medication Regimens for Acute Low Back Pain
Low back pain causes 2.4% of visits to US emergency departments (ED) resulting in 2.7 million visits annually. In a general low back pain (LBP) population, prognosis is poor.
- Trial name
- NCT01587274
- Testing
- Naproxen, Cyclobenzaprine, Oxycodone/ acetaminophen
- Where
- United States
- Volunteers
- 323 people
- Sponsor
- Montefiore Medical Center
Postural Low Back Pain, Mechanical Low Back Pain
To Evaluate the Superiority of Fixed Combination (Orfenadrine 35mg, Acetaminophen 325mg, Caffeine 65mg and Diclofenac Sodium 50mg) Compared to Voltaren® (Diclofenac Sodium 50mg) in the Treatment of Acute Postural Low Back Pain.
The purpose of this study is to determine whether the fixed combination of orphenadrine, acetaminophen, caffeine and diclofenac sodium is more effective in the treatment of an acute episode of mechanical postural low back pain…
- Trial name
- Eiffel (NCT02985671)
- Testing
- orphenadrine, acetaminophen, caffeine and diclofenac sodium, Diclofenac Sodium 50 MG
- Volunteers
- 110 people
- Sponsor
- Ache Laboratorios Farmaceuticos S.A.
Acute Muscle Pain
Evaluation of Efficacy and Safety of SPARC1401 in Acute Low Back Pain
A phase 2 randomized clinical trial to evaluate efficacy and safety of SPARC1401 at three dose levels in patients with acute low back pain
- Trial name
- NCT02887534
- Testing
- SPARC1401-low dose, SPARC1401-mid dose, SPARC1401-high dose
- Sponsor
- Sun Pharma Advanced Research Company Limited
Non-traumatic Low Back Pain
Comprehensive Biopsychosocial Approach for Acute Low Back Pain Management in the Emergency Department: a Stepped-wedge Cluster-randomized Clinical Trial
Acute low back pain, the second leading cause of medical consultations in France, poses a major public health challenge, particularly because of its high risk of progressing to chronic low back pain-the leading cause worldwide of…
- Trial name
- CALM-ED (NCT07375914)
- Testing
- Biopsychosocial intervention
- Where
- France
- Volunteers
- 782 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Low Back Pain, Shoulder Pain
An Efficacy and Safety Study of Tramadol Hydrochloride-Paracetamol in Treatment of Moderate to Severe Acute Neck-Shoulder Pain and Low Back Pain
The purpose of this study is to evaluate the efficacy and safety of tramadol hydrochloride-paracetamol tablets in treatment of moderate (medium level of seriousness) to severe (very serious) acute neck, shoulder and low back pain…
- Conditions
- Low Back Pain, Shoulder Pain, Neck Pain
- Trial name
- NCT01843660
- Testing
- Tramadol HCl-Paracetamol
- Volunteers
- 1,059 people
- Sponsor
- Xian-Janssen Pharmaceutical Ltd.
Low Back Pain
Study of the Efficacy of Manual Therapy for a Subgroup of Acute Non-specific Low Back Pain
The purpose of this study is: To validate or not the interest of the classification using the pragmatic application of clinical predictive rule for low back pain to identify patients with good prognosis following a brief spinal…
- Trial name
- NCT01801553
- Testing
- Spinal manipulation, Usual medical care
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Université Catholique de Louvain