Clinical trials: Acute Medical Conditions
Appendicitis Acute, Appendicitis
Safety & Feasibility of PERIsign System in Demonstrating Involuntary Muscle Defense as a Sign of Peritonitis in Subjects With Appendicitis
This will be an explorative, proof-of-principle, open, multi-center investigation. The investigation aims to investigate the safety of the PERIsign system and the ability of physicians to differentiate between healthy individuals…
- Conditions
- Appendicitis Acute, Appendicitis, Abdominal Pain, Peritonitis
- Trial name
- PeriSaFe01 (NCT06296953)
- Testing
- PERIsign examination
- Where
- 2 sites in Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- STB INN AB
Exercise Addiction, Control Condition
Effects of Moderate Exercise And Interval Exercise On Sleep Quality
This study aimed to explore the effects of a single bout of moderate- aerobic continuous exercise (MACE) and high-intensity intermittent exercise (HIIE) on sleep during continuous night shifts in medical shift workers with mild…
- Trial name
- EX&sleep (NCT06638359)
- Testing
- moderate exercise, interval exercise
- Where
- Taiwan
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- National Taiwan Sport University
Coronavirus Disease, COVID-19
The Effect of Smart Sensor Combined With APP for Individualized Precise Exercise Training in Long Covid-19
The coronavirus (COVID -19) has rapidly turned into a global pandemic. For patients diagnosed with COVID-19, it caused severe damage in the upper respiratory system and systemic complications, including the cardiovascular…
- Conditions
- Coronavirus Disease, COVID-19, Long Covid-19, Telerehabilitation
- Trial name
- NCT05922865
- Testing
- KNEESUP smart knee assistive device + KNEESUP care APP, Healthy consulation
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shang-Lin Chiang
Lung Diseases
The Effectiveness of Acupressure for Managing Postoperative Pain and Anxiety in Patients With Thoracoscopic Surgery
The purpose of this study is to explore the effectiveness of acupressure for managing postoperative pain, anxiety, analgesia consumption, early ambulation, and comfort in patients with thoracoscopic surgery.
- Trial name
- NCT04595253
- Testing
- acupressure
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wei-Fen Ma
Scar, Trauma Injury
The Use of Fractional Ablative CO2 Laser vs Control on Acute Traumatic Injuries to Prevent Scar Formation
Surgical standard for treating traumatic burn injury scarring is to wait one year following the initial assault prior to beginning treatment.
- Conditions
- Scar, Trauma Injury, Burns, Wound Heal
- Trial name
- NCT03888703
- Testing
- Fractional ablative CO2 laser
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Miami Dermatology and Laser Institute
Emergency Medical Services, Nursing Care
High-Sensitivity Troponin I in Addition to Guideline-Based Care in EMS
The TIGER study is a study investigating the utlility of a point-of-care blood analyse of Troponin I to help identify patients with heart attacks in the prehospital emergency care.
- Conditions
- Emergency Medical Services, Nursing Care, Cardiology, Myocardial Infarction
- Trial name
- TIGER (NCT07008391)
- Testing
- high sensitivity Troponin I
- Where
- Sweden
- Volunteers
- 1,419 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Maternal, Pediatric Care Emergencies
Does Simulation Scenario Execution Improve Acute Care Skills and Confidence Related to Maternal and Pediatric Care Emergencies?
In Uganda and many countries in Sub-Saharan Africa, health providers have minimal training and intermittent opportunity to maintain skills in managing delivery complications and acute newborn and pediatric conditions.
- Trial name
- SimForLife (NCT03258073)
- Testing
- Medical simulation using scenario execution
- Where
- Uganda
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mbarara University of Science and Technology
Acute Coronary Syndromes, ST Elevation Myocardial Infarction
Smartphone AI Assistance for Prehospital ECG Interpretation
Prehospital providers interpret 12-lead electrocardiograms (ECGs) under time pressure and without immediate expert support. Missed acute coronary occlusion - occlusion myocardial infarction (OMI) - delays reperfusion, while false…
- Conditions
- Acute Coronary Syndromes, ST Elevation Myocardial Infarction, Non-ST Elevated Myocardial Infarction, Myocardial Infarction (MI)
- Trial name
- ECG-IA (NCT07810686)
- Testing
- Smartphone large language model assistance (GPT-4o, version-locked)
- Where
- Switzerland
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- École Supérieure de Soins Ambulanciers - College of Higher Education in Prehospital Care
Knee Arthroscopy, Acute Pain
"Comparison of Intra-articular of 0.2% Ropivacaine vs. 0.75% Ropivacaine in Postoperative of Knee Arthroscopy"
All patients with acute lesions that attend the orthopedic and trauma center of the ABC medical center are invited to participate in the study.
- Trial name
- ropivacaine (NCT05807945)
- Testing
- Ropivacaine 0.75% Injectable Solution, Ropivacaine 0.2% Injectable Solution
- Where
- Mexico
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Paola M Zamora Munoz
Pressure Ulcer, Skin Lesion
Prevention of Skin Damage in the Patient in Prone Position: Development of Education Interventions Based on a Training Needs Assessment Study.
This is study 1 of 3 - of the overall project: The ProneTection Quality Improvement Project. The three aims of this study, study 1 are: 1.
- Conditions
- Pressure Ulcer, Skin Lesion, Acute Respiratory Distress Syndrome
- Trial name
- NCT05238870
- Testing
- Interviews for the needs analysis. No intervention.
- Where
- 2 sites in Belgium
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Ghent
Anesthesia, Acute Pain
Construction of Perioperative Medical Data Platform and Its Typical Practice to Predict Postoperative Acute Moderate to Severe Pain With Machine Learning Models
Data intelligence platform was widely used to facilitate the process of clinical research. However, a platform that integrates natural language processing (NLP) and machine learning (ML) algorithms has not been reported in…
- Conditions
- Anesthesia, Acute Pain, Risk Reduction
- Trial name
- NCT05569460
- Testing
- No intervention
- Where
- China
- Volunteers
- 6,500 people, healthy volunteers welcome
- Sponsor
- Guangdong Second Provincial General Hospital
Ambulances, Traumatic Brain Injury
Differences in Mortality and Morbidity in Patients Suffering a Time-critical Condition Between GEMS and HEMS
Introduction: Patients suffering a time-critical medical condition require rapid prehospital assessment and treatment and most often quick transportation to definitive care. This can be decisive for patient outcome.
- Conditions
- Ambulances, Traumatic Brain Injury, Acute Myocardial Infarction
- Trial name
- NCT03940443
- Where
- Sweden
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Dalarna County Council, Sweden
Long-COVID, Post-COVID
ASAP - Assisted Immediate Augmented Post-/Long-COVID Plan for Patients Infected With COVID-19
Post-/long-COVID occurs in patients with severe, moderate, and even mild courses. The symptomatology is multi-layered and complex.
- Conditions
- Long-COVID, Post-COVID, Psychosomatic Disorder, Psychological Distress
- Trial name
- ASAP (NCT05238415)
- Testing
- Psychological and Physiological Assessments
- Where
- Germany
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Sonia Lippke
State Anxiety, Psychological Stress
Can Increased Medical Competence Reduce State Anxiety in Junior Doctors in the Emergency Department?
This randomized controlled trial investigates whether an adaptive e-learning program on acute and time critical medical conditions can reduce state anxiety and improve the competence of junior doctors working in emergency…
- Conditions
- State Anxiety, Psychological Stress, Education, Medical, E-learning
- Trial name
- MINDED (NCT06842394)
- Testing
- Adaptive E-learning
- Where
- Denmark
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
SARS-CoV Infection
COVID-19 Vaccine Response in Chronic Respiratory Conditions
The investigators will assess the antibody, T cell and B cell responses to SARS-CoV-2 vaccination before and every 3 months for 18 months after the initial vaccination or subsequent vaccinations (boosters) in adults and children…
- Trial name
- NCT05313087
- Testing
- COVID-19 vaccine
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- National Jewish Health
Acute Pain, Anxiety
Effects of Complementary Therapies Delivered Via Mobile Technologies
The purpose of this study is to determine the effects of complementary therapies delivered via mobile technologies have a therapeutic effect on surgical patients' anxiety, pain, and self-efficacy in healing reports before…
- Conditions
- Acute Pain, Anxiety, Self Efficacy
- Trial name
- NCT02236455
- Testing
- Audio Relaxation Technique, Medical Music Intervention, Nature Therapy without Music
- Where
- Iceland
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of San Francisco
Emergencies, Tricyclic Antidepressant Poisoning
Medical Checklists in the Emergency Department
This study aims to investigate whether the use of medical checklists in the emergency department can decrease resuscitation time in critically ill patients.
- Conditions
- Emergencies, Tricyclic Antidepressant Poisoning, Tricyclic Antidepressant Toxicity
- Trial name
- NCT05496114
- Testing
- Checklist
- Where
- Netherlands
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Cardiovascular Disease Acute, Emergency Department Patient
Cardiac point-of Care Ultrasound Training Pathway for Emergency Department Advanced Practice Providers
The aim of this study is to assess emergency medicine physician and advanced practice provider (APP) knowledge and technical skill in performance of a point-of-care ultrasound simulation and just-in-time training pathway to…
- Conditions
- Cardiovascular Disease Acute, Emergency Department Patient, Heart Failure Acute, Pulmonary Embolism (Diagnosis)
- Trial name
- NCT07159269
- Testing
- Cardiac point-of-care ultrasound (POCUS) training and clinical pathway
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Duke University