Clinical trials: Acute Pain, completed
Migraine, Head Pain
A Study Comparing the Effectiveness and Safety of ULTRACET® (Tramadol HCl/Acetaminophen) Versus Placebo for the Treatment of Acute Pain From a Migraine Headache
The purpose of this study is to evaluate the effectiveness and safety of tramadol HCl/acetaminophen as a pain medication compared with placebo in the treatment of acute pain from a migraine headache.
- Conditions
- Migraine, Head Pain, Headache
- Trial name
- NCT00297375
- Testing
- tramadol HCl/acetaminophen
- Volunteers
- 375 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Low Back Pain, Pain, Chronic
Pain Neuroscience Education for Acute and Sub-Acute Low Back Pain
To determine if Pain Neuroscience Education (PNE) would result in positive clinical changes in patients presenting with acute or sub-acute low back pain (LBP).
- Conditions
- Low Back Pain, Pain, Chronic, Pain, Back
- Trial name
- NCT03722394
- Testing
- Pain Neuroscience Education
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Nevada, Las Vegas
Emergencies, Diagnostic Imaging
Abdominal Plain X-ray in the Emergency Departement
There are only few recognized indications for the realization of plain abdominal X-rays in the emergency departement. The objective of this study is to explore the reasons for abdominal plain X-rays prescription in the Emergency…
- Conditions
- Emergencies, Diagnostic Imaging, Abdomen, Acute
- Trial name
- NCT02980081
- Testing
- abdominal plain x-ray
- Where
- Switzerland
- Volunteers
- 1,997 people
- Sponsor
- University Hospital, Geneva
Pain
Intranasal Hydromorphone for the Treatment of Acute Pain in Children: A Pilot Study.
Intranasal hydromorphone has been shown to be effective in reducing acute pain in adults. It has not been previously studied in children, but may be a viable option for effectively and safely reducing pain in children by…
- Trial name
- NCT02437669
- Testing
- Hydromorphone
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Columbia University
Multiple Rib Fractures, Pain, Acute
Ultrasound-guided Deep Versus Superficial Continuous Serratus Anterior Plane Block for Pain Management in Patients With Multiple Rib Fractures
The present clinical study will be undertaken to evaluate the effect of Ultrasound-guided Deep versus Superficial continuous Serratus Anterior Plane Block for pain management in patients with multiple rib fractures.
- Conditions
- Multiple Rib Fractures, Pain, Acute, Serratus Anterior Plane Block
- Trial name
- NCT04575272
- Testing
- Ultrasound-guided continuous serratus anterior plane block
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Assiut University
Musculoskeletal Pain, Acute Pain
A Randomized Trial of NSAID Dosing Strategies
This study will compare the efficacy of two different non-steroidal anti-inflammatory drugs (NSAIDs) ketorolac and ibuprofen for people with acute moderate or severe musculoskeletal pain.
- Trial name
- NCT05239767
- Testing
- NSAID
- Where
- United States
- Volunteers
- 407 people
- Sponsor
- Montefiore Medical Center
Acute Coronary Syndrome, Chest Pain
High-Sensitivity Cardiac Troponin T to OPtimize Chest Pain Risk Stratification
This is a prospective observational cohort study of ED patients with acute chest pain or other symptoms suggestive of ACS. Blood samples will be collected from study participants for High-Sensitivity Cardiac Troponin T (hs-cTnT)…
- Trial name
- STOP CP (NCT02984436)
- Testing
- Blood Sample, HEART Score
- Where
- 6 sites in United States
- Volunteers
- 1,572 people
- Sponsor
- University of Florida
Lordosis, Low Back Pain
Comparing the Effects of Muscle Energy Technique Versus Myofascial Mobilization in Managing Sub-acute Low Back Pain
Institute for Clinical Systems Improvement (ICSI) defines sub-acute low back pain as low back pain lasting between 4 and 12 weeks.
- Trial name
- NCT05428280
- Testing
- Physiotherapy, Muscle Energy technique, Myofacial mobilization
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Dow University of Health Sciences
Opioid Use, Acute Pain
Appropriate Opioid Quantities for Acute Pain - Pharmacist Study
Prescription opioids contribute to opioid related deaths, overdose and addiction. Unused prescribed opioids are not routinely being stored or disposed of appropriately and their availability is associated with harms.
- Trial name
- NCT04484610
- Testing
- Pharmacist Practice Change to Dispense Appropriate Opioid Quantities for Acute Pain
- Where
- Canada
- Volunteers
- 205 people
- Sponsor
- Centre for Addiction and Mental Health
Post-thoracotomy Pain Syndrome
Erector Spinae Plane Block for Post-thoracotomy Pain Control
The thoracic epidural block (TEB) and thoracic paravertebral block (TPVB) are the most commonly used techniques for analgesia after thoracic surgery.Recently, erector spinae plane block (ESPB) was reported as a treatment for…
- Trial name
- NCT04531553
- Testing
- Thoracic epidural analgesia, ESPB with levobupivacaine and dexmedetomedine, ESPB with levobupivacaine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt
Pain, Acute Postoperative, Trauma Injury
Patient-Titrated Automated Intermittent Boluses of Local Anesthetic vs. a Continuous Infusion Via a Perineural Catheter for Postoperative Analgesia
This will be a randomized comparison of continuous local anesthetic infusion with patient controlled boluses (PCA) to patient-titratable automated boluses with patient controlled boluses (PCA) for both infraclavicular and…
- Trial name
- NCT05091905
- Testing
- Continuous Infusion of ropivacaine 0.2%, Titratable Automated Intermittent Boluses of ropivacaine 0.2%
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, San Diego
Bunionectomy, Pain
A Trial to Evaluate CG5503 Efficacy and Safety in Acute Pain After Bunionectomy
The main objective of this trial is to demonstrate the efficacy and safety of multiple-dose application of oral application of CG5503 IR 75mg compared to placebo and to assess safety and tolerability of CG5503 IR 75mg in subjects…
- Conditions
- Bunionectomy, Pain, Postoperative Pain, Acute Pain
- Trial name
- NCT00609466
- Testing
- CG5503 IR, Morphine
- Where
- 6 sites in United States
- Volunteers
- 291 people
- Sponsor
- Grünenthal GmbH
Pain, Acute
Efficacy and Safety of Penthrox® Combined With a Standard Analgesia (SoC) in Adult Patients Admitted to the Emergency Department With Moderate to Severe Pain Associated With Trauma
A phase 4 randomised, double-blind study to assess the efficacy and safety of Penthrox® used from the outset in multimodal analgesia, in combination with the standard analgesic protocol used in the department, for conscious adult…
- Trial name
- Pen ASAP (NCT03798899)
- Testing
- Methoxyflurane, Normal Saline
- Where
- 8 sites in France
- Volunteers
- 360 people
- Sponsor
- Mundipharma SAS
Postoperative Pain After Thoracic Surgery, Postoperative Pain
Comparison of IV Analgesia Protocols After the Regional Block's Effect Diminishes in Thoracic Surgery
The purpose of this study is to compare the effectiveness of three different intravenous (IV) patient-controlled analgesia (PCA) regimens-Fentanyl, Tramadol, and Ibuprofen-in managing postoperative pain and respiratory…
- Conditions
- Postoperative Pain After Thoracic Surgery, Postoperative Pain, Thoracic Surgery, Video Assisted, Patient Controlled Analgesia
- Trial name
- NCT07610408
- Testing
- Fentanyl IV PCA, Tramadol IV PCA, Ibuprofen IV PCA
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Ankara Etlik City Hospital
Acute Pain
Ketamine Versus Morphine Change Pain Profile
The aim of this study is to evaluate the efficacy of intravenous low dose ketamine infusion versus morphine infusion analgesia for pain reduction in Abdominoplasty surgery
- Trial name
- NCT03664622
- Testing
- Ketamine, Morphine
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Cairo University
Osteoarthritis, Rheumatoid Arthritis
A Phase 1 Clinical Trial to Evaluate the Safety and Pharmacokinetic Characteristics of DW1809
Randomized, Open-label, Oral, Single-dose, two-Sequence, four-Period, crossover study
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Back Pain, Acute Upper Respiratory Tract Infection
- Trial name
- NCT05214677
- Testing
- DW1809, DW1809-1
- Where
- South Korea
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Elbow Tendinopathy
Effect of Tissue Flossing on Pain,Function and Movement
The purpose of the current investigation is to examine the effect of tissue-flossing on upper extremity, pain, strength and functional performance in subjects with musculoskeletal-related complaints of pain surrounding the elbow…
- Trial name
- NCT04899375
- Testing
- Floss band, ACE bandage
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- New York Institute of Technology
Diverticulitis, Colonic
Unexpected Diagnosis in Right Lower Quadrant Pain: Right Colon Diverticulitis
BACKGROUND: Acute right lower quadrant pain is a common symptom in emergency departments. The most common etiology is thought to be acute appendicitis. Other etiologies may be overlooked.
- Trial name
- NCT06153030
- Testing
- no intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Haydarpasa Numune Training and Research Hospital
Mobility Limitation, Spinal Fusion
Physical Therapy Using Virtual Reality/Augmented Reality
The purpose of this study is to determine if non-invasive distracting devices (Virtual Reality (VR) headset, Augmented Reality (AR) Headset) are more effective than the standard of care (i.e., no technology-based distraction) for…
- Conditions
- Mobility Limitation, Spinal Fusion, Acute Pain
- Trial name
- NCT03874507
- Testing
- Virtual Reality/Augmented Reality Headset
- Where
- 2 sites in United States
- Volunteers
- 41 people
- Sponsor
- Stanford University
Breast Cancer
Pecs II Block and PaB Could be an Alternative in Breast Surgery
The association between ultrasound-guided Pecs II block and parasternal block can represent a valid alternative in the management of acute and postoperative pain syndrome after quadrantectomy with or without axillary dissection.
- Trial name
- NCT02865265
- Testing
- Pecs II and parasternal blocks
- Volunteers
- 180 people
- Sponsor
- Emiliano Petrucci
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